Frontiers in Pharmacology | Ethnopharmacology

Original Research

Published on 02 Dec 2025

TCMRGAT: Relational graph attention networks for predicting stroke treatment efficacy of traditional Chinese medicine prescriptions

in Ethnopharmacology

Ning Cheng
Changsong Ding
Xuekun Song

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1570094

1,072 views

Original Research

Accepted on 01 Dec 2025

An ethnopharmacological assessment of medicinal plants in Malanje municipality, Angola

in Ethnopharmacology

Agostinho António Barroso
André Alberto Martins
Agostinho Morais
Bernardo Nicodemo Chimbuco
Peterson Catenda
Yanelis Saucedo Hernández
Dany Siverio Mota
Mateus Ferreira Gonçalves
Venancio Ribalta Ribalta
Mateus Sebastião

Frontiers in Pharmacology

363 views

Correction

Published on 01 Dec 2025

Correction: Geniposide plus chlorogenic acid reverses non-alcoholic steatohepatitis via regulation of gut microbiota and bile acid signaling in a mouse model in vivo

in Ethnopharmacology

Hongshan Li
Yingfei Xi
Xin Xin
Qin Feng
Yiyang Hu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1657343

1,181 views

Review

Accepted on 30 Nov 2025

Pharmacological potential of Chinese botanical drugs in managing chronic kidney disease by targeting mitochondrial quality control

in Ethnopharmacology

Hongyu Liu
Shumin Huang
Shichun Chen
Shuzhen Liang
Minying Huang
Shiyu Li
Yongxiang Xu
Baocheng Xie

Frontiers in Pharmacology

253 views

Systematic Review

Published on 28 Nov 2025

Efficacy and safety of the commercial Chinese polyherbal preparation Liu Shen Wan as an adjunctive treatment for herpes zoster and postherpetic neuralgia: a systematic review and meta-analysis

in Ethnopharmacology

Yajing Li
Le Zhang
Wenya Wang
Hui Zhao
Xing Liao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1698753

1,374 views

Original Research

Published on 28 Nov 2025

Electrostatically driven fluorescent sensor for rapid detection of AChE activity and organophosphate pesticides via dual-enzyme cascade amplification

in Ethnopharmacology

Xiaoyi Liu
Kunhui Sun
Sitong Lai
Guojing Liu
Meifang Li
Ping Wang
Shuhong Wang
Lan Ma
Xie-An Yu
Wei Lei

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1679948

813 views

Original Research

Published on 28 Nov 2025

Balanophora polysaccharide improves renal injury and fibrosis in db/db diabetic nephropathy mice via NLRP3 inflammasome mediated inflammation

in Ethnopharmacology

Chaoxi Tian
Aolong Ma
Tianying Song
Fangyu Zhao
Jing Huang
Jianhong Gao
Honglin Yan
Xianbing Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1671678

1,140 views

Original Research

Published on 27 Nov 2025

Shaoyao gancao decoction induces autophagy by modulating miR-21 and inhibiting the AKT/mTOR signaling pathway in adenomyosis-derived ectopic endometrial stromal cells

in Ethnopharmacology

Huijie Lai
Jinjin Jia
Zijun Kuang
Jie Lu
Yuyan Zeng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1665911

1,301 views

Review

Published on 27 Nov 2025

Silymarin as a phytopharmaceutical agent: advances in mechanistic insights, formulation strategies, and pre-clinical applications

in Ethnopharmacology

Mahewish Sayyad
Ashish Dilip Sutar
Kamini Shivhare
Rahul Shukla
Swaran J. S. Flora

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1711653

2,775 views

Review

Published on 27 Nov 2025

Evaluation of natural products bioactivity in cardiovascular diseases utilizing zebrafish models: a comprehensive review

in Ethnopharmacology

Yiming Wang
Xiang Meng
Xuting Song
Lulu Wang
Xianghe Meng
Xiaoya Du
Ziyoviddin Yusupov
Komiljon Tojibaev
Yunpeng Wang
Min He

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1713417

1,184 views

Original Research

Published on 27 Nov 2025

Polyphenol-rich Morus nigra L. extract mitigates neuroinflammation and cognitive impairment through gut–brain axis modulation in an Alzheimer’s disease rat model

in Ethnopharmacology

Yue Li
Yangyi Zhang
Mengwen Liu
Tuerxunayi Dawuti
Xuanshi Chen
Hui Xiao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1695768

1,460 views

Mini Review

Published on 26 Nov 2025

Mini-review: The health benefits and applications of allicin

in Ethnopharmacology

Ke-Qian Chen
Hai-Bo Lei
Xiang Liu
Wen-Jing Cao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1715922

2,603 views

Original Research

Published on 26 Nov 2025

Identification, biotransformation, and neuroprotective potential of the ethanol extract of Alpiniae oxyphyllae fructus in neuroinflammation-related cognitive impairment

in Ethnopharmacology

Zirong Yi
Xinyu Wang
Lin Wang
Renfang Yin
Dongying Qi
Huan Liu
Yuxin Chen
Yamei Xie
Yuming Ma
Mengqi Hu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1714500

841 views

Clinical Trial

Published on 26 Nov 2025

Efficacy and safety of Centella asiatica (L.) Urb. [Apiaceae] as a dietary supplement for glycemic control and lipid regulation in patients with type 2 diabetes: a randomized controlled trial in Thailand

in Ethnopharmacology

Weeratian Tawanwongsri
Auemphon Mordmuang
Tharin Phenwan
Doungkamol Siri-archawawat

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1680647

1,094 views

Review

Published on 26 Nov 2025

Natural products intervene in non-alcoholic fatty liver disease by regulating the AMPK signaling pathway: preclinical evidence and mechanism

in Ethnopharmacology

Chuyue Zhang
Jianing Shi
Lijun Shi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1696506

2,143 views
1 citation

Mini Review

Published on 26 Nov 2025

Botanical drug preparations for alleviating hair loss in menopausal women: a global ethnopharmacological mini-review

in Ethnopharmacology

Zhuo Huang
Wen-Jie Zhao
Yong-Jie Gao
Zhi-Rong Huang
Qing-Rui Huang
Sui-Zhen Cai
Ming-Hui Bi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1725691

2,250 views

Clinical Trial

Published on 25 Nov 2025

Clinical efficacy and metabolomics profiling of dachaihu decoction for patients with septic liver injury: a randomized controlled trial

in Ethnopharmacology

Zhen Yang
Xingyu Kao
Tianwei Zhu
Junna Lei
Na Huang
Jingli Chen
Mingfeng He
Qi Tang
Zhangrong Liang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1671732

1,496 views

Review

Published on 25 Nov 2025

Therapeutic efficacy and mechanisms of gentiopicroside in various diseases

in Ethnopharmacology

Ling Kui
Guoyun Wang
Jinqun Huang
Xiaonan Yang
Jinshi Yu
Xi Li
Huaming Peng
Bingfeng Leng
Yinming Jiao
Zhanjiang Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1634722

2,570 views

Original Research

Published on 25 Nov 2025

Identification of active metabolites from Gentiana scabra Bunge ethanol-water extract for chicken metatarsal fracture repair

in Ethnopharmacology

Yi Jiang Liu
Yue Min Wang
Bin Jiang
Hou Qiang Luo
Su Zhen Liu
Shuai Luo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1706754

843 views
1 citation

Mini Review

Published on 25 Nov 2025

Harnessing marine algal polysaccharides for combination cancer therapy: pharmacological mechanisms and clinical perspectives

in Ethnopharmacology

Jing Zhong
Sookja Kim Chung
Xiaoling Han
Riming Huang
Baojun Xu
Io Nam Wong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1682025

1,074 views

Review

Published on 25 Nov 2025

Integrating clinical evidence with natural product therapies for elderly-onset type 2 diabetes

in Ethnopharmacology

Chae-Eun Kim
Kyong Kim
Eun-Young Park
Yoon Sin Oh

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1658881

1,305 views

Original Research

Published on 25 Nov 2025

Allocryptopine, tetrahydropalmatine, and tetrahydroberberine N-oxide alkaloids alleviate cellular stress by modulating calcium homeostasis and the MAPK and akt/GSK-3β/tau signaling pathways

in Ethnopharmacology

Serap Nigdelioglu Dolanbay
Belma Aslim

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1589390

1,141 views

Original Research

Published on 25 Nov 2025

Selaginella extracts extend lifespan and mitigate oxidative stress in Caenorhabditis elegans

in Ethnopharmacology

Xueqing Chen
Bingjian Yan
Yingmei Wu
Wenjing Quan
Yu Liu
Yaning Huang
Yinjie Shao
Yuan Wang
Qi Zhou
Yifei Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1658991

1,265 views

Original Research

Published on 25 Nov 2025

Sporoderm-removed ganoderma lucidum spore powder (S-GLSP) alleviates neuroinflammation injury by regulating microglial polarization through inhibition of NLRP3 inflammasome activation

in Ethnopharmacology

Wenli Li
Wei Huang
Peng Zhou
Yongchuan Yao
Biao Cai
Shu Ye

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1690192

1,248 views

5,867 articles

articles

TCMRGAT: Relational graph attention networks for predicting stroke treatment efficacy of traditional Chinese medicine prescriptions

An ethnopharmacological assessment of medicinal plants in Malanje municipality, Angola

Correction: Geniposide plus chlorogenic acid reverses non-alcoholic steatohepatitis via regulation of gut microbiota and bile acid signaling in a mouse model in vivo

Pharmacological potential of Chinese botanical drugs in managing chronic kidney disease by targeting mitochondrial quality control

Efficacy and safety of the commercial Chinese polyherbal preparation Liu Shen Wan as an adjunctive treatment for herpes zoster and postherpetic neuralgia: a systematic review and meta-analysis

Electrostatically driven fluorescent sensor for rapid detection of AChE activity and organophosphate pesticides via dual-enzyme cascade amplification

Balanophora polysaccharide improves renal injury and fibrosis in db/db diabetic nephropathy mice via NLRP3 inflammasome mediated inflammation

Shaoyao gancao decoction induces autophagy by modulating miR-21 and inhibiting the AKT/mTOR signaling pathway in adenomyosis-derived ectopic endometrial stromal cells

Silymarin as a phytopharmaceutical agent: advances in mechanistic insights, formulation strategies, and pre-clinical applications

Evaluation of natural products bioactivity in cardiovascular diseases utilizing zebrafish models: a comprehensive review

Polyphenol-rich Morus nigra L. extract mitigates neuroinflammation and cognitive impairment through gut–brain axis modulation in an Alzheimer’s disease rat model

Mini-review: The health benefits and applications of allicin

Identification, biotransformation, and neuroprotective potential of the ethanol extract of Alpiniae oxyphyllae fructus in neuroinflammation-related cognitive impairment

Efficacy and safety of Centella asiatica (L.) Urb. [Apiaceae] as a dietary supplement for glycemic control and lipid regulation in patients with type 2 diabetes: a randomized controlled trial in Thailand

Natural products intervene in non-alcoholic fatty liver disease by regulating the AMPK signaling pathway: preclinical evidence and mechanism

Botanical drug preparations for alleviating hair loss in menopausal women: a global ethnopharmacological mini-review

Clinical efficacy and metabolomics profiling of dachaihu decoction for patients with septic liver injury: a randomized controlled trial

Therapeutic efficacy and mechanisms of gentiopicroside in various diseases

Identification of active metabolites from Gentiana scabra Bunge ethanol-water extract for chicken metatarsal fracture repair

Harnessing marine algal polysaccharides for combination cancer therapy: pharmacological mechanisms and clinical perspectives

Integrating clinical evidence with natural product therapies for elderly-onset type 2 diabetes

Allocryptopine, tetrahydropalmatine, and tetrahydroberberine N-oxide alkaloids alleviate cellular stress by modulating calcium homeostasis and the MAPK and akt/GSK-3β/tau signaling pathways

Selaginella extracts extend lifespan and mitigate oxidative stress in Caenorhabditis elegans

Sporoderm-removed ganoderma lucidum spore powder (S-GLSP) alleviates neuroinflammation injury by regulating microglial polarization through inhibition of NLRP3 inflammasome activation