Frontiers in Pharmacology | Ethnopharmacology

Original Research

Accepted on 22 Dec 2025

Mechanisms and safety evaluation of stir-fried Atractylodis Macrocephalae Rhizoma with Aurantii Fructus in the treatment of inflammatory bowel disease: a study based on organ-on-a-chip model

in Ethnopharmacology

Weidong Zhang
Chanming Liu
Wei Chen
Yueqin Zhu
Zhengrong Gu
Ping Xue
Xin Zhuang
Yuan Wei
Jiexian Ye
Xi Xu

Frontiers in Pharmacology

111 views

Original Research

Accepted on 22 Dec 2025

Study on the effect and mechanism of Ershiyiwei Lvronghao Concentrated Pills in the treatment of nonalcoholic fatty liver disease

in Ethnopharmacology

Yexin Wu
Bin Chen
Jintao Long
Mingxin Pai
Zhiyong Xiao
Qun Huang
Kang Li
Bengui Ye

Frontiers in Pharmacology

Review

Accepted on 22 Dec 2025

Targeting Lipophagy and Nuclear Receptors in Metabolic-Associated Fatty Liver Disease: Insights from Traditional Chinese Medicine

in Ethnopharmacology

Ting Yue
Nafei Huang
Ziming Zhao
YU LILI
Xiaoming He
Xiao Yu
YI ZHENG

Frontiers in Pharmacology

Review

Accepted on 22 Dec 2025

Oleaceae Plants: A Source of Metabolites with Atheroprotective Potential

in Ethnopharmacology

Agnieszka Anna Filipek
Edyta Czepielewska

Frontiers in Pharmacology

106 views

Review

Accepted on 22 Dec 2025

Ethnopharmacological Considerations of Plants Traditionally Used by Local Communities to Manage Maternal Conditions in Tanzania: A Scoping Review

in Ethnopharmacology

Mwanaidi Omary
Maryyusta Nguyamu
Jackline Nkoma
Hamisi Japhari
Obadia K. Bishoge
Emanuel L. Peter

Frontiers in Pharmacology

Original Research

Accepted on 19 Dec 2025

A Significant Gap between Inadequate Pharmacotherapy and Substantial Unmet Needs in Palmar Hyperhidrosis Management in China: Insights from a Questionnaire-Based Survey among Outpatients

in Ethnopharmacology

Ning Pang
Yi Liu
Chaoqun Ma
Yingkun Liu
Lin Huang
Xiaohong Zhang
Yanguo Liu

Frontiers in Pharmacology

778 views

Systematic Review

Accepted on 19 Dec 2025

Glycyrrhizic acid and glycyrrhetinic acid, natural products of Glycyrrhiza uralensis Fisch.: pharmacological and biological activities, pharmacokinetics, toxicological effects, and clinical applications to diseases

in Ethnopharmacology

HUA ZHANG
Chun-li Wu
Ruoyu Chao
Xiang-yu Zhao
Yan-wei Zhang
Qinwei Fu
Qinxiu Zhang
Jianlin WU

Frontiers in Pharmacology

194 views

Review

Published on 19 Dec 2025

Recent advances in natural polysaccharides for type 2 diabetes management: sources, structural characteristics, and mechanistic insights

in Ethnopharmacology

Zexiang Liu
Hanlong Wang
Xiujuan Gong
Xiao Jiang
Kangyi Yang
Linfang Jiang
Zhihui Wang
Qiaozhen Tong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1705122

687 views

Clinical Trial

Published on 19 Dec 2025

Effects and safety of a CBD-rich Cannabis sativa oil in knee osteoarthritis: a double-blind, randomized, placebo-controlled trial – CANOA – cannabis for osteoarthritis

in Ethnopharmacology

Andrés Mojoli
Osvaldo Haider
Yasmin Fakih
Maria Victoria Luz Gonçalves
Bruno Zepeda Rojas
Giovanna Xaia
Emanuelly Krefta
Maíra Assunção Bicca
Thiago Lopes de Mari
Charles Francisco Ferreira

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1657065

792 views

Systematic Review

Published on 19 Dec 2025

Effectiveness and safety of Ayurvedic intervention in essential hypertension: a systematic review with meta-analysis

in Ethnopharmacology

Saylee Deshmukh
Kuldeep Choudhary
Azeem Ahmad
Govind Reddy
B. C. S. Rao
Narayanam Srikanth
Rabinarayan Acharya

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1695614

1,626 views

Original Research

Published on 19 Dec 2025

Emodin and physcion alleviate cholestatic liver injury by targeting FXR: hepatoprotective components identified in processed Polygonum multiflorum Thunb. using a comprehensive two-dimensional biochromatography system

in Ethnopharmacology

Zhihui Li
Yanqiu Gu
Jianbo Yang
Shaozhan Wang
Shengnan Li
Panpan Chen
Ru Yao
Fangbin Liu
Ying Wang
Rong Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1706401

658 views

Mini Review

Published on 19 Dec 2025

Abhraka Bhasma (mica based nanomedicine): an ayurvedic herbomineral perspective in breast cancer management

in Ethnopharmacology

Dhanya Soman Pillai
Amarnath Karavettekudy Ranjit

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1656846

717 views

Review

Accepted on 18 Dec 2025

Plant Polysaccharides in Neuroprotection: Mechanistic Insights Across Central Nervous System Disorders.

in Ethnopharmacology

Qiyue Yu
Hui Chen
Zhuofeng Qu
Jialin Qu
Yan Wang
Lina Liang
Shouyu Hu

Frontiers in Pharmacology

Systematic Review

Published on 18 Dec 2025

Synergistic antitumor effects of astragalus polysaccharide: a preclinical systematic review and meta-analysis

in Ethnopharmacology

Ruo Zhang
Qian Yang
Zhi Chen
Jianming Huang
Guonan Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1672450

695 views

Original Research

Published on 18 Dec 2025

A warming-yang herbal decoction protects against high-altitude hypoxia–induced osteoblast injury through modulation of HIF-1 signaling

in Ethnopharmacology

Xuehai Liu
Yaqian Qi
Rui Zhao
Binkui Jia
Xilin Lei
Hongfan Li
Di Wang
Haoling Zhang
Wei Wang
Zhijing Song

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1673146

426 views

Original Research

Published on 18 Dec 2025

Harnessing natural terpenes via PEGylated mucoadhesive vesicles for improved urinary bladder delivery: from in vitro evaluation to in vivo assessment

in Ethnopharmacology

Hayder A. Hammoodi
Rofida Albash
Mohammed I. A. Hamed
Khaled M. Darwish
Amira B. Kassem
Asmaa Saleh
Jawaher Abdullah Alamoudi
Noha M. Badawi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1685423

420 views

Original Research

Published on 18 Dec 2025

Anti-inflammatory effect of a pimarane diterpenoid isolated from Nepeta adenophyta Hedge based on a network analysis approach and experimental assessment

in Ethnopharmacology

Wei Zhao
Meng Li
Chuanqing Jia
Iftikhar Ali
Long Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1652902

506 views

Original Research

Accepted on 17 Dec 2025

Benefit-risk Assessment of the use of toxic botanical drugs in superiority field: A case study on Aconitum carmichaeli Debx

in Ethnopharmacology

Xiaomeng Zhang
Bing Zhang
Jintao Lyv
Zhijian Lin
Xinlong Liu

Frontiers in Pharmacology

Review

Accepted on 17 Dec 2025

Metabolite and Gut Microbiota Co-Biomarkers in Danggui Shaoyao San: Insights into a Shared Therapeutic Approach

in Ethnopharmacology

Xin Fu
Dinghan Peng
Yang Yu
Mingguo Cao
Xin Zheng
Songquan Wu

Frontiers in Pharmacology

Review

Accepted on 16 Dec 2025

Harnessing Curcumin in Oral Medicine: Mechanisms, Therapeutic Potential, and Future Innovations

in Ethnopharmacology

Chengchen Hu
Shengguo Wang
Zhi Gao
Maofeng Qing
Lian Tan
Lu Yang
Fang Li

Frontiers in Pharmacology

225 views

Review

Accepted on 16 Dec 2025

Policy and Legal Perspectives on the Traditional Chinese Medicine Varietal Protection System (TCMVPS): Reform or Abolition?

in Ethnopharmacology

Yanhui Wang
Ke Sun
Dong Hua

Frontiers in Pharmacology

313 views

Systematic Review

Accepted on 16 Dec 2025

Preclinical evidence of ginkgo biloba extract on diabetic nephropathy: A systematic review and meta-analysis

in Ethnopharmacology

Jiangteng Liu
Ying Tang
Zhixun Guo
Zhichao Ruan
Yexin Chen
Yuanyuan Lin
Xingru Pan
Weijun Huang
Jinxi Zhao

Frontiers in Pharmacology

112 views

Review

Accepted on 16 Dec 2025

Exploring cannabinoid modulation on autophagy mechanisms in Alzheimer's disease: A review

in Ethnopharmacology

Claudia Ntsapi
Morne Weyers
Rosa Chinheya
Tsebo Tsebo Jim
Motlalepula Gilbert Matsabisa

Frontiers in Pharmacology

114 views

Original Research

Published on 16 Dec 2025

Integrated gut microbiota and metabolomics analysis reveals the antitumor effects of ergosta-4,6,8(14),22-tetraen-3-one purified from the medicinal fungus pholiota adiposa in tumor-bearing mice

in Ethnopharmacology

Boyuan Liu
Junsen Qin
Shan Zheng
Jiaxin Zhang
Xuemei Hu
Xiaoyan Wang
Yan Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1653035

735 views

5,779 articles

articles

Mechanisms and safety evaluation of stir-fried Atractylodis Macrocephalae Rhizoma with Aurantii Fructus in the treatment of inflammatory bowel disease: a study based on organ-on-a-chip model

Study on the effect and mechanism of Ershiyiwei Lvronghao Concentrated Pills in the treatment of nonalcoholic fatty liver disease

Targeting Lipophagy and Nuclear Receptors in Metabolic-Associated Fatty Liver Disease: Insights from Traditional Chinese Medicine

Oleaceae Plants: A Source of Metabolites with Atheroprotective Potential

Ethnopharmacological Considerations of Plants Traditionally Used by Local Communities to Manage Maternal Conditions in Tanzania: A Scoping Review

A Significant Gap between Inadequate Pharmacotherapy and Substantial Unmet Needs in Palmar Hyperhidrosis Management in China: Insights from a Questionnaire-Based Survey among Outpatients

Glycyrrhizic acid and glycyrrhetinic acid, natural products of Glycyrrhiza uralensis Fisch.: pharmacological and biological activities, pharmacokinetics, toxicological effects, and clinical applications to diseases

Recent advances in natural polysaccharides for type 2 diabetes management: sources, structural characteristics, and mechanistic insights

Effects and safety of a CBD-rich Cannabis sativa oil in knee osteoarthritis: a double-blind, randomized, placebo-controlled trial – CANOA – cannabis for osteoarthritis

Effectiveness and safety of Ayurvedic intervention in essential hypertension: a systematic review with meta-analysis

Emodin and physcion alleviate cholestatic liver injury by targeting FXR: hepatoprotective components identified in processed Polygonum multiflorum Thunb. using a comprehensive two-dimensional biochromatography system

Abhraka Bhasma (mica based nanomedicine): an ayurvedic herbomineral perspective in breast cancer management

Plant Polysaccharides in Neuroprotection: Mechanistic Insights Across Central Nervous System Disorders.

Synergistic antitumor effects of astragalus polysaccharide: a preclinical systematic review and meta-analysis

A warming-yang herbal decoction protects against high-altitude hypoxia–induced osteoblast injury through modulation of HIF-1 signaling

Harnessing natural terpenes via PEGylated mucoadhesive vesicles for improved urinary bladder delivery: from in vitro evaluation to in vivo assessment

Anti-inflammatory effect of a pimarane diterpenoid isolated from Nepeta adenophyta Hedge based on a network analysis approach and experimental assessment

Benefit-risk Assessment of the use of toxic botanical drugs in superiority field: A case study on Aconitum carmichaeli Debx

Metabolite and Gut Microbiota Co-Biomarkers in Danggui Shaoyao San: Insights into a Shared Therapeutic Approach

Harnessing Curcumin in Oral Medicine: Mechanisms, Therapeutic Potential, and Future Innovations

Policy and Legal Perspectives on the Traditional Chinese Medicine Varietal Protection System (TCMVPS): Reform or Abolition?

Preclinical evidence of ginkgo biloba extract on diabetic nephropathy: A systematic review and meta-analysis

Exploring cannabinoid modulation on autophagy mechanisms in Alzheimer's disease: A review

Integrated gut microbiota and metabolomics analysis reveals the antitumor effects of ergosta-4,6,8(14),22-tetraen-3-one purified from the medicinal fungus pholiota adiposa in tumor-bearing mice