Frontiers in Pharmacology | Ethnopharmacology

Original Research

Published on 26 Jun 2025

Geum japonicum Thunb. exhibits anti-platelet activity via the regulation of cyclic guanosine monophosphate

in Ethnopharmacology

Yuan Yee Lee
Abdul Wahab Akram
Young-Hee Kim
Muhammad Irfan
Sung Dae Kim
Evelyn Saba
Tae Wan Kim
Bong-Sik Yun
Man Hee Rhee

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1538417

270 views

Original Research

Published on 26 Jun 2025

Baicalein from Scutellaria baicalensis mitigates oxidative stress through the IIS pathway in a C. elegans model of ulcerative colitis

in Ethnopharmacology

Wei Wang
Xiaoyu Fu
Jianing Xu
Weiguang Lv
Shengnan Han
Yi Wang
Yu Xia
Jing Han
Ke Li
Chenggang Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1592244

328 views

Original Research

Published on 26 Jun 2025

Effects of Dendrobium officinale Kimura & Migo flower flavonoids on cognitive function by regulating gut microbiota

in Ethnopharmacology

Nanzhi Hu
Kaiyue Wang
Xing Ge
Xin Zhang
Xiaojie Zheng
Shifang Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1562775

363 views

Original Research

Published on 26 Jun 2025

In vitro antimicrobial and cytotoxic evaluation of leaf, root, and stem extracts of Solanum dasyphyllum and root and stem extracts of Dovyalis abyssinica

in Ethnopharmacology

Dereilo Bekere Belitibo
Asfaw Meressa
Temesgen Negassa
Abiy Abebe
Sileshi Degu
Milkyas Endale
Frehiwot Teka Assamo
Temesgen Abdisa Ayana
Getahun Tadesse Gurmessa
Negera Abdissa

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1529854

445 views

Original Research

Published on 26 Jun 2025

Mechanisms of Lushi Runzao decoction in Treating Sjögren’s syndrome by remodeling gut flora to regulate bile acid and short-chain fatty acid metabolism

in Ethnopharmacology

Fengtao Pang
Quan Jiang
Xiaopo Tang
Kesong Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1505642

322 views

Original Research

Published on 26 Jun 2025

Molecular mechanisms underlying Fagopyrum dibotrys-derived nanovesicles induced ferroptosis in hepatocellular carcinoma: a dual-pathway analysis of lipid peroxidation and mitochondrial damage

in Ethnopharmacology

Ling Wu
Hongyao Chen
Jingting Zhang
Jincheng Tang
Zhibin Wang
Peisen Xue
Wenhui Gao
Renyi Yang
Puhua Zeng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1636149

303 views

Original Research

Published on 26 Jun 2025

Tanshinone I promotes angiogenesis and improves ventricular remodeling post-myocardial infarction via ALDH2 signaling-mediated ferroptosis inhibition

in Ethnopharmacology

Feng Zhang
Lei Li
Qian Liu
Wen-Long Wang
Zhi-Xin Wang
Rong-Qiang Song
Jian Sun
Yi-Yi Zhang
Xin-Chen Ren
Dong Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1601017

237 views

Original Research

Accepted on 25 Jun 2025

Exosomal miR-93-3p Targets EIF4EBP1 to Regulate Macrophage Polarization and Accelerate Wound Healing Post-anal Fistula Surgery

in Ethnopharmacology

Wenzhe Feng
Wei Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1599633

Original Research

Accepted on 25 Jun 2025

Therapeutic Efficacy of Rhoifolin in Type 2 Diabetes Mellitus: Effects on Metabolic Parameters, Hepatic Function, and Oxidative Stress: A Dose-Dependent Study

in Ethnopharmacology

Sndos Z Fattiny
Manal Abdulaziz Binobead
Abu ElGasim Yagoub
Ghedeir Alshammari
Ali Saleh
Mohammed Abdo Yahya

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1595323

Original Research

Accepted on 25 Jun 2025

The active components of Eucommia ulmoides leaves alleviates atherosclerosis induced by high-fat diet and VD3 in rats

in Ethnopharmacology

Man Gong
Lili Zhu
Bingdi Cui
Cong Ling
Xiaoqian Liu
Zhimin Wang
Liping Dai

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1625200

165 views

Systematic Review

Accepted on 25 Jun 2025

Protective effects of curcumin on epileptic rodent models by alleviating oxidative stress and inflammation: a meta-analysis and mechanism exploration

in Ethnopharmacology

Peng Dai
Lingyu Xu
Peng Zhang
Zheng Liang
Yunhang Chu
Ziqiao Yu
Lin Cao
Peng Sun
Xia Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1602716

Original Research

Accepted on 25 Jun 2025

Multi-omics reveals Abelmoschus manihot (L.) Medik. flavonoids ameliorate MAFLD via PI3K/AKT/mTOR-mediated autophagy

in Ethnopharmacology

Chao Lv
Lei Zhao
Jiani Hou
Hongyin Sun
Zhongsha Li
Yuesong Wu
Peizheng Shi
Yaping Xiao
Yunjin Xie
Wei Su

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1601707

Original Research

Published on 25 Jun 2025

Shi Wei Ru Xiang pill alleviates acute gouty arthritis through suppressing NLRP3 inflammasome activation

in Ethnopharmacology

Na Wang
Puchen Zhao
Qin Yin
Lizi Li
Haiqi Xu
Can Yang
Yanbei Tu
Yanfang Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1595578

358 views

Original Research

Published on 25 Jun 2025

Pterostilbene mitigates experimental pulmonary arterial hypertension by inhibiting endothelial-to-mesenchymal transition

in Ethnopharmacology

Jie Wang
Yu Zhang
Junjun Liu
Fan Jiang
Xiaopei Cui
Weida Lu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1621700

396 views

Original Research

Published on 25 Jun 2025

Targeting mitophagy in diabetic retinopathy: novel insights into SQSTM1/BNIP3L pathway regulated by luteolin

in Ethnopharmacology

Shuyan Zhang
Jiajun Wu
Yinjian Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1593213

297 views

Original Research

Accepted on 24 Jun 2025

Iridoids derived from Valeriana jatamansi Jones alleviates neuroinflammation and blood spinal cord barrier permeability after spinal cord injury by activating the Nrf2/HO-1 signaling pathway

in Ethnopharmacology

Yongzhi He
Jiachun Lu
Rizhao Pang
Lijuan Ding
Yunyun Wang
Hua Xiao
Chao Cheng
Yushan Luo
Xiaomin Hu
Wenchun Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1597719

169 views