Frontiers in Pharmacology | Ethnopharmacology

Original Research

Published on 21 Jan 2026

Ginsenoside Rk1 alleviates lipopolysaccharide (LPS)-induced cognitive impairment by modulating synaptic plasticity

in Ethnopharmacology

Xuesong Zhang
Funan Ning
Biqun Zhang
Jiaqi Ji
Junzuo Zheng
Xiaosong Hu
Zhiang Liu
Li Ding
Ping Wang
Zhou Lan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1747574

638 views

Review

Published on 21 Jan 2026

Astragaloside IV is a potential natural neuroprotective agent for stroke: a review

in Ethnopharmacology

Qiao-Li Zhang
Wen-Xiu Qin
Xiu-Juan Li
Yun-Bo Zhang
Ming Li
Jun-Feng Xu
Zhong-Nan Mao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1718700

754 views

Original Research

Published on 21 Jan 2026

Mechanism of Yiqi Huoxue Granule in promoting angiogenesis of skin lesion tissue by increasing CSF2 to reduce mesenchymal stem cell apoptosis

in Ethnopharmacology

Weili Shi
Shuhui Wang
Shanshan Liu
Zhen Lei
Peishuo Yan
Xinzhou Wang
Chaoqun Lu
Nan Qin
Pengfei Lu

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1649017

905 views

Original Research

Published on 21 Jan 2026

Differences in the content of five bioactive components in Dendropanax dentiger (Harms) Merr. from different production areas and their correlation with geographic distribution and climatic factors

in Ethnopharmacology

Lan Lan
Jiale Mao
Weiqun Chen
Shuang Liu
Tao Li
Xiaohui Zhou
Tongtong Chen
Zhouxin Yuan
Houxing Lei
Zhen Hu

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1702672

395 views

Original Research

Published on 21 Jan 2026

Gingerenone A attenuates diabetic vascular remodeling through AMPK/mTOR/S6K1 signaling

in Ethnopharmacology

Meixian Chen
Daqian Gu
Yi Lin
Junwei Zhou
Wansheng Lin
Zhi Chen
Zhurong Luo
Pin Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1706103

631 views

Original Research

Published on 21 Jan 2026

Pharmacological effects and phytochemical profile of methanolic Odontosoria biflora (Kaulf.) C.Chr. [Lindsaeaceae] extract in Caenorhabditis elegans models of Parkinson’s disease

in Ethnopharmacology

Meysam Hamel Darbandi
Leslie Michelle M. Dalmacio
Jose Ma M. Angeles

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1662877

3,130 views

Systematic Review

Accepted on 20 Jan 2026

Effect of compound kushen injection on immune function in patients with primary liver cancer: a systematic review and meta-analysis

in Ethnopharmacology

Yu Xiong
Yutong Cai
Chenxi Li
Qian Yan
Xiongwen Wang
Xiaoying Zhang

Frontiers in Pharmacology

171 views

Original Research

Accepted on 20 Jan 2026

Formulation and In vitro Evaluation of an Anti-inflammatory Herbal Suppository containing Peperomia pellucida

in Ethnopharmacology

W. A. D. J. Thanishka
D. M. W. L. Dassanayake
D. M. S. R. Dimbulgahamada
W. D. U. S. Fernando
N. T. B. Dias
H. H. V. K. N. De Silva
B. L. C. Samanmali

Frontiers in Pharmacology

253 views

Correction

Published on 20 Jan 2026

Correction: Cannabis-based extract for managing pain in dogs with osteoarthritis: efficacy and safety assessment

in Ethnopharmacology

Neide Maria Griebeler
Ricardo Penayo Cremonese
Yasmin Rafaela Fakih Correa
Priscila Romero Mazzini Pereira
Amanda Furjan Rial
Emanuela Leite
Maria Victoria Luz Gonçalves
Luiz Renato Marques das Almas
Nedice Borges Cardoso
Fernando Cezar-dos-Santos

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1758996

497 views

Systematic Review

Published on 20 Jan 2026

The effect of plant active substances on cognitive function in healthy older adults: a systematic review and network meta-analysis of randomized controlled trials

in Ethnopharmacology

Xueyan Feng
Shuangbo Fan
Fengqin Wei

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1672171

1,215 views

Systematic Review

Published on 20 Jan 2026

Traditional herbal medicine for obesity-related polycystic ovary syndrome: a meta-analysis and data mining study

in Ethnopharmacology

Lei Tang
Haijuan Liu
Ying Pang
Guohua Wang
Zheng Wang
Tianyao Lv

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1738172

1,203 views

Review

Accepted on 19 Jan 2026

Efficacy and Safety of Common Chinese Herbal Medicines in Treating Psoriasis: A Systematic Review and Meta-Analysis

in Ethnopharmacology

Meng-yun ZHOU
Yang SUN
Tian-hong XU
Hui Zhang
Xiujiao Xia

Frontiers in Pharmacology

545 views

Original Research

Accepted on 19 Jan 2026

Effect of Shugan Jieyu capsule combined with group psychological counseling on alexithymia in hemodialysis patients

in Ethnopharmacology

Xiaojie Gao
Xiaoling Li
Cuiying Yang

Frontiers in Pharmacology

172 views

Systematic Review

Accepted on 16 Jan 2026

Preclinical Evidence of the Therapeutic Effect of Moringa oleifera in Peptic Ulcer Disease: A Systematic Review and Meta-Analysis

in Ethnopharmacology

Saheed Olatunbosun Akiode
Adeoti Gbemisola Adeniran
Oyedayo Phillips Akano
Kamoru Abdulazeez Adeniyi
Ayokunmi Stephen Olusa
Oghale Oghenefego Ovuakporie-Uvo
Uwaisu Iliyasu
Olunike Abodunrin
Folahanmi Akinsolu
Olajide Odunayo Sobande

Frontiers in Pharmacology

365 views

Systematic Review

Published on 16 Jan 2026

Traditional herbal medicine for opioid-induced constipation in patients with cancer: a systematic review and meta-analysis of randomized controlled trials

in Ethnopharmacology

Su Hyeon Lee
Hayun Jin
Eun Hye Kim
Seong Woo Yoon

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1716974

666 views

Mini Review

Published on 16 Jan 2026

Fucoidan as a renal protectant: mechanistic insights and therapeutic implications of endothelial glycocalyx targeting

in Ethnopharmacology

Ping Xin
Chengqiao Ge
Yufan Tang
Yifan He
Bin Fu

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1749109

913 views

Original Research

Published on 16 Jan 2026

Yangjing Shugan decoction targets the Sirt1/Nrf2 antioxidant pathway and gut microbiota-metabolite axis to protect against premature ovarian failure

in Ethnopharmacology

Ling Yang
Li Liu
Junbo Liu
Meng Ran Xu
Jing Ren
Bo Li
Lili Jiao
Yunyan Wei
Jing Wang
Yi Guo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1722692

802 views

Systematic Review

Published on 15 Jan 2026

Comparative effectiveness of ten traditional Chinese herbal formulas for acute exacerbation of chronic obstructive pulmonary disease: a systematic review and Bayesian network meta-analysis

in Ethnopharmacology

Enze Yu
Chunyan Tian
Pengna Jiang
Xingyi Wang
Yuting Yin
Zhuying Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1585150

1,353 views

Original Research

Published on 15 Jan 2026

Neuroprotective and anti-inflammatory activity of Wyethia species: therapeutic potential for neurodegenerative diseases

in Ethnopharmacology

Idowu Jonas Sagbo
David Soriano-Castell
Jon Rebman
Pamela Maher

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1740121

700 views

Original Research

Published on 15 Jan 2026

Bushen Huoxue decoction alleviates bisphenol a-induced infertility through the PMK-1 mitogen-activated protein kinases signaling pathway and downstream mitochondrial unfolded protein response in Caenorhabditis elegans

in Ethnopharmacology

Linlin Chen
Kanglu Wu
Chenyi Shou
Lijun Zhang
Mengya Tu
Borui Wang
Yun Cai
Zihui Zheng
Jia Sun
Qinli Ruan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1713681

830 views

Review

Accepted on 14 Jan 2026

Multi-Target Intervention Mechanisms and Prospects of the Traditional Chinese Medicine Scutellaria baicalensis Georgi in Alzheimer's Disease

in Ethnopharmacology

MingHao Zhao
Miao Zhang
SiQi Zhang
GuoCheng Xue
XuanTong Hou
HuiHui Wang
YuBo Yang
XinYu Yan

Frontiers in Pharmacology

155 views

Original Research

Accepted on 14 Jan 2026

Exploring the Anti-fibrotic Effects of Safflower in Systemic Sclerosis Based on Metabolomics and Gut Microbiota Analyses

in Ethnopharmacology

YU ZHANG
Xingfeng Ping
Xueyan Zhou
Yi Huang
Kai LI
Junying Lv

Frontiers in Pharmacology

178 views

Review

Published on 14 Jan 2026

Multi-target regulatory mechanisms and clinical assessment of natural products for insomnia: a review

in Ethnopharmacology

Dongchuan Ma
Hao Yang
Maoyuan Zhao
Zhaoliang Luo
Renyi Teng
Xiaofei Huang
Tingting Liu
Shangbin Lv
Mingyu Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1681709

950 views

Review

Published on 14 Jan 2026

The treatment of myocardial ischemia-reperfusion injury: potential roles of natural drug modulating CaMKII

in Ethnopharmacology

Kai Yang
Ping Zhang
Xianshan Hui
Chao Liu
Jun Li
Yongmei Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1718008

833 views

5,867 articles

articles

Ginsenoside Rk1 alleviates lipopolysaccharide (LPS)-induced cognitive impairment by modulating synaptic plasticity

Astragaloside IV is a potential natural neuroprotective agent for stroke: a review

Mechanism of Yiqi Huoxue Granule in promoting angiogenesis of skin lesion tissue by increasing CSF2 to reduce mesenchymal stem cell apoptosis

Differences in the content of five bioactive components in Dendropanax dentiger (Harms) Merr. from different production areas and their correlation with geographic distribution and climatic factors

Gingerenone A attenuates diabetic vascular remodeling through AMPK/mTOR/S6K1 signaling

Pharmacological effects and phytochemical profile of methanolic Odontosoria biflora (Kaulf.) C.Chr. [Lindsaeaceae] extract in Caenorhabditis elegans models of Parkinson’s disease

Effect of compound kushen injection on immune function in patients with primary liver cancer: a systematic review and meta-analysis

Formulation and In vitro Evaluation of an Anti-inflammatory Herbal Suppository containing Peperomia pellucida

Correction: Cannabis-based extract for managing pain in dogs with osteoarthritis: efficacy and safety assessment

The effect of plant active substances on cognitive function in healthy older adults: a systematic review and network meta-analysis of randomized controlled trials

Traditional herbal medicine for obesity-related polycystic ovary syndrome: a meta-analysis and data mining study

Efficacy and Safety of Common Chinese Herbal Medicines in Treating Psoriasis: A Systematic Review and Meta-Analysis

Effect of Shugan Jieyu capsule combined with group psychological counseling on alexithymia in hemodialysis patients

Preclinical Evidence of the Therapeutic Effect of Moringa oleifera in Peptic Ulcer Disease: A Systematic Review and Meta-Analysis

Traditional herbal medicine for opioid-induced constipation in patients with cancer: a systematic review and meta-analysis of randomized controlled trials

Fucoidan as a renal protectant: mechanistic insights and therapeutic implications of endothelial glycocalyx targeting

Yangjing Shugan decoction targets the Sirt1/Nrf2 antioxidant pathway and gut microbiota-metabolite axis to protect against premature ovarian failure

Comparative effectiveness of ten traditional Chinese herbal formulas for acute exacerbation of chronic obstructive pulmonary disease: a systematic review and Bayesian network meta-analysis

Neuroprotective and anti-inflammatory activity of Wyethia species: therapeutic potential for neurodegenerative diseases

Bushen Huoxue decoction alleviates bisphenol a-induced infertility through the PMK-1 mitogen-activated protein kinases signaling pathway and downstream mitochondrial unfolded protein response in Caenorhabditis elegans

Multi-Target Intervention Mechanisms and Prospects of the Traditional Chinese Medicine Scutellaria baicalensis Georgi in Alzheimer's Disease

Exploring the Anti-fibrotic Effects of Safflower in Systemic Sclerosis Based on Metabolomics and Gut Microbiota Analyses

Multi-target regulatory mechanisms and clinical assessment of natural products for insomnia: a review

The treatment of myocardial ischemia-reperfusion injury: potential roles of natural drug modulating CaMKII