Frontiers in Pharmacology | Ethnopharmacology

Systematic Review

Accepted on 28 Nov 2025

Neuroprotective effects of traditional Chinese medicine formulas in animal models of retinal degenerative diseases: A systematic review and meta-analysis

in Ethnopharmacology

Yunxi Xu
Qindong Mi
Qi Yong
Chao Xu
Dingmeng Zhao
Chuning Wang
Zhongshan Jiang
Chenghao Yu
Hejiang Ye

Frontiers in Pharmacology

240 views

Original Research

Accepted on 28 Nov 2025

Elucidating the Mechanism of Moluodan in Treating Chronic Non-Atrophic Gastritis: An Integrated Approach Combining Clinical Proteomics, Network Pharmacology, and Experimental Validation

in Ethnopharmacology

Yuetian Xu
Feiyue Zhao
He Jiang
Qichao Liu
Menglei Wang
Pengchao Bai
Huiyun Liu
Ruikang Jia

Frontiers in Pharmacology

204 views

Systematic Review

Published on 28 Nov 2025

Efficacy and safety of the commercial Chinese polyherbal preparation Liu Shen Wan as an adjunctive treatment for herpes zoster and postherpetic neuralgia: a systematic review and meta-analysis

in Ethnopharmacology

Yajing Li
Le Zhang
Wenya Wang
Hui Zhao
Xing Liao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1698753

979 views

Original Research

Published on 28 Nov 2025

Electrostatically driven fluorescent sensor for rapid detection of AChE activity and organophosphate pesticides via dual-enzyme cascade amplification

in Ethnopharmacology

Xiaoyi Liu
Kunhui Sun
Sitong Lai
Guojing Liu
Meifang Li
Ping Wang
Shuhong Wang
Lan Ma
Xie-An Yu
Wei Lei

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1679948

504 views

Original Research

Published on 28 Nov 2025

Balanophora polysaccharide improves renal injury and fibrosis in db/db diabetic nephropathy mice via NLRP3 inflammasome mediated inflammation

in Ethnopharmacology

Chaoxi Tian
Aolong Ma
Tianying Song
Fangyu Zhao
Jing Huang
Jianhong Gao
Honglin Yan
Xianbing Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1671678

756 views

Original Research

Accepted on 27 Nov 2025

Data Mining Historical Chinese Medical Recipe Collections and Nuclear Receptor Profiling Identify Plant Fractions that Modulate Glucocorticoid Receptor Activity

in Ethnopharmacology

Joachim Prackwieser
René Houtman
Tim Kievitz
Diana Melchers
Haifeng Guan
Georg Johannes Seifert
Frank Konietschke
Kai Lamottke
Paul Ulrich Unschuld
Nalini Kirk

Frontiers in Pharmacology

175 views

Original Research

Published on 27 Nov 2025

Shaoyao gancao decoction induces autophagy by modulating miR-21 and inhibiting the AKT/mTOR signaling pathway in adenomyosis-derived ectopic endometrial stromal cells

in Ethnopharmacology

Huijie Lai
Jinjin Jia
Zijun Kuang
Jie Lu
Yuyan Zeng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1665911

709 views

Review

Published on 27 Nov 2025

Silymarin as a phytopharmaceutical agent: advances in mechanistic insights, formulation strategies, and pre-clinical applications

in Ethnopharmacology

Mahewish Sayyad
Ashish Dilip Sutar
Kamini Shivhare
Rahul Shukla
Swaran J. S. Flora

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1711653

1,130 views

Review

Published on 27 Nov 2025

Evaluation of natural products bioactivity in cardiovascular diseases utilizing zebrafish models: a comprehensive review

in Ethnopharmacology

Yiming Wang
Xiang Meng
Xuting Song
Lulu Wang
Xianghe Meng
Xiaoya Du
Ziyoviddin Yusupov
Komiljon Tojibaev
Yunpeng Wang
Min He

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1713417

665 views

Original Research

Published on 27 Nov 2025

Polyphenol-rich Morus nigra L. extract mitigates neuroinflammation and cognitive impairment through gut–brain axis modulation in an Alzheimer’s disease rat model

in Ethnopharmacology

Yue Li
Yangyi Zhang
Mengwen Liu
Tuerxunayi Dawuti
Xuanshi Chen
Hui Xiao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1695768

743 views

Original Research

Accepted on 26 Nov 2025

Antioxidant, antiaging and mitochondrial protective effects of JadeAging in Caenorhabditis elegans

in Ethnopharmacology

Bowen Lu
Dongli Yin
Yilei Wang
Xue Wang
Shengcan Zou
Jiacheng Li

Frontiers in Pharmacology

142 views

Mini Review

Published on 26 Nov 2025

Mini-review: The health benefits and applications of allicin

in Ethnopharmacology

Ke-Qian Chen
Hai-Bo Lei
Xiang Liu
Wen-Jing Cao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1715922

1,478 views

Original Research

Published on 26 Nov 2025

Identification, biotransformation, and neuroprotective potential of the ethanol extract of Alpiniae oxyphyllae fructus in neuroinflammation-related cognitive impairment

in Ethnopharmacology

Zirong Yi
Xinyu Wang
Lin Wang
Renfang Yin
Dongying Qi
Huan Liu
Yuxin Chen
Yamei Xie
Yuming Ma
Mengqi Hu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1714500

611 views

Clinical Trial

Published on 26 Nov 2025

Efficacy and safety of Centella asiatica (L.) Urb. [Apiaceae] as a dietary supplement for glycemic control and lipid regulation in patients with type 2 diabetes: a randomized controlled trial in Thailand

in Ethnopharmacology

Weeratian Tawanwongsri
Auemphon Mordmuang
Tharin Phenwan
Doungkamol Siri-archawawat

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1680647

601 views

Mini Review

Published on 26 Nov 2025

Botanical drug preparations for alleviating hair loss in menopausal women: a global ethnopharmacological mini-review

in Ethnopharmacology

Zhuo Huang
Wen-Jie Zhao
Yong-Jie Gao
Zhi-Rong Huang
Qing-Rui Huang
Sui-Zhen Cai
Ming-Hui Bi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1725691

1,271 views

Review

Published on 26 Nov 2025

Natural products intervene in non-alcoholic fatty liver disease by regulating the AMPK signaling pathway: preclinical evidence and mechanism

in Ethnopharmacology

Chuyue Zhang
Jianing Shi
Lijun Shi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1696506

943 views

Original Research

Accepted on 25 Nov 2025

Wound healing and photodynamic potential of Adiantum capillus-veneris L. (Pteridaceae): An evaluation of the cellular effects and molecular insights

in Ethnopharmacology

Linru Mou
Banaz Jalil
Francesca Scotti
Majella E. Lane
Bernd L. Fiebich
Lu Sun
Caroline Maake
Michael Heinrich

Frontiers in Pharmacology

166 views

Original Research

Accepted on 25 Nov 2025

Yangjing Shugan Decoction targets the Sirt1/Nrf2 antioxidant pathway and gut microbiota-metabolite axis to protect against premature ovarian failure

in Ethnopharmacology

Ling Yang
Li Liu
Junbo Liu
Meng Ran Xu
Jing Ren
Bo Li
Lili Jiao
Yunyan Wei
Jing Wang
Yi Guo

Frontiers in Pharmacology

106 views

Original Research

Accepted on 25 Nov 2025

The role of total polysaccharides from Sonchus arvensis L. for the prevention and treatment of colitis via regulating gut microbiota and metabolites

in Ethnopharmacology

Yachao Ren
shenghua hou
guoyou chen
Yulong Zhou

Frontiers in Pharmacology

106 views

Review

Published on 25 Nov 2025

Therapeutic efficacy and mechanisms of gentiopicroside in various diseases

in Ethnopharmacology

Ling Kui
Guoyun Wang
Jinqun Huang
Xiaonan Yang
Jinshi Yu
Xi Li
Huaming Peng
Bingfeng Leng
Yinming Jiao
Zhanjiang Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1634722

1,718 views

Clinical Trial

Published on 25 Nov 2025

Clinical efficacy and metabolomics profiling of dachaihu decoction for patients with septic liver injury: a randomized controlled trial

in Ethnopharmacology

Zhen Yang
Xingyu Kao
Tianwei Zhu
Junna Lei
Na Huang
Jingli Chen
Mingfeng He
Qi Tang
Zhangrong Liang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1671732

912 views

Original Research

Published on 25 Nov 2025

Identification of active metabolites from Gentiana scabra Bunge ethanol-water extract for chicken metatarsal fracture repair

in Ethnopharmacology

Yi Jiang Liu
Yue Min Wang
Bin Jiang
Hou Qiang Luo
Su Zhen Liu
Shuai Luo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1706754

442 views

Mini Review

Published on 25 Nov 2025

Harnessing marine algal polysaccharides for combination cancer therapy: pharmacological mechanisms and clinical perspectives

in Ethnopharmacology

Jing Zhong
Sookja Kim Chung
Xiaoling Han
Riming Huang
Baojun Xu
Io Nam Wong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1682025

689 views

Original Research

Published on 25 Nov 2025

Allocryptopine, tetrahydropalmatine, and tetrahydroberberine N-oxide alkaloids alleviate cellular stress by modulating calcium homeostasis and the MAPK and akt/GSK-3β/tau signaling pathways

in Ethnopharmacology

Serap Nigdelioglu Dolanbay
Belma Aslim

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1589390

724 views

5,779 articles

articles

Neuroprotective effects of traditional Chinese medicine formulas in animal models of retinal degenerative diseases: A systematic review and meta-analysis

Elucidating the Mechanism of Moluodan in Treating Chronic Non-Atrophic Gastritis: An Integrated Approach Combining Clinical Proteomics, Network Pharmacology, and Experimental Validation

Efficacy and safety of the commercial Chinese polyherbal preparation Liu Shen Wan as an adjunctive treatment for herpes zoster and postherpetic neuralgia: a systematic review and meta-analysis

Electrostatically driven fluorescent sensor for rapid detection of AChE activity and organophosphate pesticides via dual-enzyme cascade amplification

Balanophora polysaccharide improves renal injury and fibrosis in db/db diabetic nephropathy mice via NLRP3 inflammasome mediated inflammation

Data Mining Historical Chinese Medical Recipe Collections and Nuclear Receptor Profiling Identify Plant Fractions that Modulate Glucocorticoid Receptor Activity

Shaoyao gancao decoction induces autophagy by modulating miR-21 and inhibiting the AKT/mTOR signaling pathway in adenomyosis-derived ectopic endometrial stromal cells

Silymarin as a phytopharmaceutical agent: advances in mechanistic insights, formulation strategies, and pre-clinical applications

Evaluation of natural products bioactivity in cardiovascular diseases utilizing zebrafish models: a comprehensive review

Polyphenol-rich Morus nigra L. extract mitigates neuroinflammation and cognitive impairment through gut–brain axis modulation in an Alzheimer’s disease rat model

Antioxidant, antiaging and mitochondrial protective effects of JadeAging in Caenorhabditis elegans

Mini-review: The health benefits and applications of allicin

Identification, biotransformation, and neuroprotective potential of the ethanol extract of Alpiniae oxyphyllae fructus in neuroinflammation-related cognitive impairment

Efficacy and safety of Centella asiatica (L.) Urb. [Apiaceae] as a dietary supplement for glycemic control and lipid regulation in patients with type 2 diabetes: a randomized controlled trial in Thailand

Botanical drug preparations for alleviating hair loss in menopausal women: a global ethnopharmacological mini-review

Natural products intervene in non-alcoholic fatty liver disease by regulating the AMPK signaling pathway: preclinical evidence and mechanism

Wound healing and photodynamic potential of Adiantum capillus-veneris L. (Pteridaceae): An evaluation of the cellular effects and molecular insights

Yangjing Shugan Decoction targets the Sirt1/Nrf2 antioxidant pathway and gut microbiota-metabolite axis to protect against premature ovarian failure

The role of total polysaccharides from Sonchus arvensis L. for the prevention and treatment of colitis via regulating gut microbiota and metabolites

Therapeutic efficacy and mechanisms of gentiopicroside in various diseases

Clinical efficacy and metabolomics profiling of dachaihu decoction for patients with septic liver injury: a randomized controlled trial

Identification of active metabolites from Gentiana scabra Bunge ethanol-water extract for chicken metatarsal fracture repair

Harnessing marine algal polysaccharides for combination cancer therapy: pharmacological mechanisms and clinical perspectives

Allocryptopine, tetrahydropalmatine, and tetrahydroberberine N-oxide alkaloids alleviate cellular stress by modulating calcium homeostasis and the MAPK and akt/GSK-3β/tau signaling pathways