Frontiers in Pharmacology | Ethnopharmacology

Original Research

Published on 20 Nov 2025

Evaluation of long-term safety profile of an EU-GMP certified Cannabis sativa L. strain in a naturally aging preclinical model

in Ethnopharmacology

Gabriela-Dumitrita Stanciu
Ivona Costachescu
Daniela-Carmen Ababei
Andrei Szilagyi
Raluca-Maria Gogu
Vlad-Constantin Craciun
Andrei-Daniel Timofte
Irina-Draga Caruntu
Cristina-Elena Dobre
Bogdan-Ionel Tamba

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1716366

762 views

Original Research

Published on 20 Nov 2025

Full-spectrum cannabis extracts for women with chronic pain syndromes: a real-life retrospective report of multi-symptomatic benefits after treatment with individually tailored dosage schemes

in Ethnopharmacology

Patrícia Montagner Soares Silva
Wesley Medeiros
Clarissa Nogueira Borges
Joaquim P. Brasil-Neto
Wilson Lessa Jr.
Ricardo Ferreira de Oliveira e Silva
Fabio V. Caixeta
Renato Malcher-Lopes

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1538518

2,284 views

Original Research

Published on 20 Nov 2025

Effects of Ophiopogon japonicus oligosaccharides on type 2 diabetes in rats via modulation of gut microbiota and metabolites

in Ethnopharmacology

Tingyu Yang
Baoting Chen
Jia Fang
Zilin Li
Yiming Liu
Aihua Lin

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1710883

1,110 views

Systematic Review

Published on 20 Nov 2025

Cardioprotective Chinese herbs and antiretroviral drug metabolism: a systematic review of in vitro evidence

in Ethnopharmacology

Wan-Jung Cheng
Anthony Jaworowski
Janine M. Trevillyan
Anna C. Hearps
Charlie C. Xue
Anthony L. Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1627058

892 views

Systematic Review

Published on 20 Nov 2025

Quercetin exhibits multi-target anti-allergic effects in animal models: a systematic review and meta-analysis of preclinical studies

in Ethnopharmacology

Zeyi Lv
Zhuo Pan
Yue Huang
Hao Yang
Xinrong Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1673712

1,630 views

Systematic Review

Published on 19 Nov 2025

Qianyang Yuyin Granules for vascular damage in mild-to-moderate hypertensive patients: a systematic review with meta-analysis and trial sequential analysis

in Ethnopharmacology

Shidian Zhu
Qiannong Wu
Yanlin Liu
Fuming Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1612508

1,014 views

Original Research

Published on 19 Nov 2025

Nettle (Urtica cannabina L.) polysaccharides as a novel dietary supplement: enhancing systemic antioxidant status via modulation of the gut–liver axis

in Ethnopharmacology

Jize Zhang
Qian Zhang
Xiaoqing Zhang
Jiang Qiao
Jingwei Wang
Yang Gao
Ping Dong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1692189

852 views

Systematic Review

Published on 19 Nov 2025

Chinese herbal injections combined with EGFR-TKIs for intervention of non-small cell lung cancer: a systematic review and meta-analysis

in Ethnopharmacology

Zichun Yuan
Mei Yan
Tongtong Wu
Ganlin Zhang
Guowang Yang
Xiaomin Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1670501

1,194 views

Systematic Review

Published on 19 Nov 2025

Effect of Sihogyeji-tang on functional dyspepsia: a systematic review and meta-analysis

in Ethnopharmacology

Hanbum Bae
Jinsung Kim
Soyeon Kim

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1689132

1,452 views

Original Research

Published on 19 Nov 2025

Protective effects of Angelica sinensis polysaccharide on chemotherapy-injured rats with premature ovarian insufficiency and its impact on gut microbiota

in Ethnopharmacology

Maoyuan Wu
Haixia Shu
Min Wang
Yan Xu
Yunhan Zhang
Xiaoling Jiang
Lixia Zhang
Xuemei Chen
Lianli He

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1685281

1,037 views

Systematic Review

Published on 19 Nov 2025

Protective effects of salvianolic acid A on ischemic stroke: A meta-analysis of preclinical studies

in Ethnopharmacology

An Liu
Wenjing Li
Hangyao Zhang
Kexin Sun
Yuqian Xiao
Jun Wan
Pin Li
Yan Wang
Sihan Hu
Yanjie Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1629258

1,112 views

Original Research

Published on 19 Nov 2025

Molecular docking and pharmacological investigations of folenolide for its analgesic, anti-inflammatory, and antipyretic applications

in Ethnopharmacology

Faryal Liaqat Ali
Fazli Khuda
Atif Ali Khan Khalil
Asif Jan
Muhammad Asif Khan
Ahmed Nadeem
Abdur Rasheed
Syed Shaukat Ali
Asmat Ullah

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1658610

1,095 views

Original Research

Published on 19 Nov 2025

Six-methoxyflavone suppresses CircPIAS1 biogenesis via targeting PTBP1 and, in combination with IFN-γ, promotes ferroptosis in melanoma

in Ethnopharmacology

Yong-Qi Guo
Xi Wu
Xin Zang
Cheng-Yan Liu
Meng-Yue Wang
Cheng-Mei Xiao
Hui Hou
Li-Fang Zhang
Yuan-Zheng Xia
Ling-Yi Kong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1681890

943 views

Review

Published on 19 Nov 2025

Therapeutic potential of common Phytoestrogens found in traditional Chinese medicine in chronic kidney diseases

in Ethnopharmacology

Tongtong Liu
Minghan Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1599097

1,300 views

Original Research

Published on 19 Nov 2025

Exosomes derived from Panax notoginseng promote osteogenic differentiation of rBMSCs via the PI3K/AKT signaling pathway

in Ethnopharmacology

Nan Wu
Lintao Zhang
Hua Guo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1682548

737 views

Review

Published on 18 Nov 2025

From bench to bedside, boswellic acids in anti-inflammatory therapy — mechanistic insights, bioavailability challenges, and optimization approaches

in Ethnopharmacology

Chuhang Peng
Yujia Yang
Yuzhi Wang
Bao Gong
Xiuting Sun
Xinquan Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1692443

1,841 views

Original Research

Published on 18 Nov 2025

Curcumol alleviates endometriosis via correcting the aberrant activation of Fas/RIPK1-mediated PANoptosis

in Ethnopharmacology

Weiming Ni
Xiaoqin Wu
Li Feng
Min Xu
Yingzhou Tian

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1691279

1,016 views

Review

Published on 17 Nov 2025

Harnessing the multi-targeted potential of rehmanniae radix natural products against renal fibrosis: a mechanistic review

in Ethnopharmacology

Keqin Zhao
Han Zhu
Liping Zheng
Wenru Wang
Peng Liu
Renhuan Yu
Xiaobei Ma

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1690036

1,120 views

Original Research

Published on 17 Nov 2025

Xinli formula’s efficacy in heart failure: analysis via Guangdong TCM hospital database

in Ethnopharmacology

Haiming Cao
Jiongming Zhang
Tong Zhang
Xiankun Chen
Tong Liu
Wenjing Xu
Yi Zhu
Wei Jiang
Weihui Lu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1661625

944 views

Review

Published on 17 Nov 2025

Advances in traditional Chinese medicine for burn treatment: mechanisms, therapeutic approaches, and innovative preparations

in Ethnopharmacology

Ying Liu
Caiyuan Yu
Tong Dou
Yang Shen
He Li
Mengyan Liu
Wenying Xie
Weijia Zeng
Zizhao Feng
Ming Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1651219

1,789 views

Review

Published on 17 Nov 2025

Ethnomedicinal, phytochemical, pharmacological, and conservation studies of an endangered plant: the desert teak (Tecomella undulata (Sm.) Seem.)

in Ethnopharmacology

Sharad Vats
Nikkee Bhandari
Showkat Ahmad Ganie
Mushtaq Ahmad Mir
Nasreena Bashir

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1665446

1,188 views

Original Research

Published on 17 Nov 2025

Comparative efficacy and safety of botanical drugs for mild cognitive impairment: a systematic review and network meta-analysis

in Ethnopharmacology

Yifan Yang
Haixia Wang
Jianmeng Lü
Hui Zhang
Tao Wang
Yongmei Yan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1657169

1,932 views

Original Research

Published on 17 Nov 2025

Fermented rice bran extract delays skin aging by increasing the synthesis of collagen and elastin

in Ethnopharmacology

Xin Yan
Meiqing Yang
Xuyi Cai
Yiwei Shen
Ruihan Jiang
Rizhong Huang
Huai-Kai Shi
Gregory Cheng
Yiwei Wang
Qian Tan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1692491

1,687 views

Original Research

Published on 17 Nov 2025

Potential anticancer effects of Peganum harmala in human papillomavirus-related cervical and head and neck cancer cells

in Ethnopharmacology

Hiba F. Muddather
Tohfa Nasibova
Gábor J. Szebeni
Nikolett Gémes
Noémi Bózsity
Renáta Minorics
Eldar Garayev
Ilkay Erdogan Orhan
Gaëtan Herbette
Zsuzsanna Schelz

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1668827

1,464 views

5,781 articles

articles

Evaluation of long-term safety profile of an EU-GMP certified Cannabis sativa L. strain in a naturally aging preclinical model

Full-spectrum cannabis extracts for women with chronic pain syndromes: a real-life retrospective report of multi-symptomatic benefits after treatment with individually tailored dosage schemes

Effects of Ophiopogon japonicus oligosaccharides on type 2 diabetes in rats via modulation of gut microbiota and metabolites

Cardioprotective Chinese herbs and antiretroviral drug metabolism: a systematic review of in vitro evidence

Quercetin exhibits multi-target anti-allergic effects in animal models: a systematic review and meta-analysis of preclinical studies

Qianyang Yuyin Granules for vascular damage in mild-to-moderate hypertensive patients: a systematic review with meta-analysis and trial sequential analysis

Nettle (Urtica cannabina L.) polysaccharides as a novel dietary supplement: enhancing systemic antioxidant status via modulation of the gut–liver axis

Chinese herbal injections combined with EGFR-TKIs for intervention of non-small cell lung cancer: a systematic review and meta-analysis

Effect of Sihogyeji-tang on functional dyspepsia: a systematic review and meta-analysis

Protective effects of Angelica sinensis polysaccharide on chemotherapy-injured rats with premature ovarian insufficiency and its impact on gut microbiota

Protective effects of salvianolic acid A on ischemic stroke: A meta-analysis of preclinical studies

Molecular docking and pharmacological investigations of folenolide for its analgesic, anti-inflammatory, and antipyretic applications

Six-methoxyflavone suppresses CircPIAS1 biogenesis via targeting PTBP1 and, in combination with IFN-γ, promotes ferroptosis in melanoma

Therapeutic potential of common Phytoestrogens found in traditional Chinese medicine in chronic kidney diseases

Exosomes derived from Panax notoginseng promote osteogenic differentiation of rBMSCs via the PI3K/AKT signaling pathway

From bench to bedside, boswellic acids in anti-inflammatory therapy — mechanistic insights, bioavailability challenges, and optimization approaches

Curcumol alleviates endometriosis via correcting the aberrant activation of Fas/RIPK1-mediated PANoptosis

Harnessing the multi-targeted potential of rehmanniae radix natural products against renal fibrosis: a mechanistic review

Xinli formula’s efficacy in heart failure: analysis via Guangdong TCM hospital database

Advances in traditional Chinese medicine for burn treatment: mechanisms, therapeutic approaches, and innovative preparations

Ethnomedicinal, phytochemical, pharmacological, and conservation studies of an endangered plant: the desert teak (Tecomella undulata (Sm.) Seem.)

Comparative efficacy and safety of botanical drugs for mild cognitive impairment: a systematic review and network meta-analysis

Fermented rice bran extract delays skin aging by increasing the synthesis of collagen and elastin

Potential anticancer effects of Peganum harmala in human papillomavirus-related cervical and head and neck cancer cells