Frontiers in Pharmacology | Ethnopharmacology

Original Research

Published on 05 Jan 2026

Phytochemical characterization and pharmacological evaluation of aerial and root parts of Dalea pazensis Rusby [Fabaceae]

in Ethnopharmacology

Mariana Andrea Peralta
Einy Nallybe Bedoya Aguirre
Melisa Fabiana Negro
Javier Echeverría
Maria Daniela Santi
Maria Gabriela Ortega

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1717359

576 views

Systematic Review

Published on 05 Jan 2026

A critical review of systematic reviews and meta-analyses of curcumin for knee osteoarthritis

in Ethnopharmacology

Jixin Chen
Qinxin Zhou
Weijie Yu
Dongdong Cao
Yingzhou Li
Jianliang Chen
Feng Ye

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1664319

1,352 views

Original Research

Published on 05 Jan 2026

Comparison of granule and traditional decoction of Gancao Xiexin for cold-heat complex pattern recurrent oral ulcer: a randomized controlled trial

in Ethnopharmacology

Si-Run Liu
Hai-Tao Zhu
Pei-Chi Chen
Yu-Yu Zeng
Rui-Min Wang
Hua-Chong Xu
Ze-Jian Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1668985

948 views

Original Research

Published on 05 Jan 2026

Harnessing red grape pomace extract for sustainable broad-spectrum photoprotection in a reconstructed human epidermis model

in Ethnopharmacology

Antonella Smeriglio
Marta Mangano
Mariarosaria Ingegneri
Annarita La Neve
Chiara Brenna
Luca Mastracci
Francesco Merlino
Giancarlo Tonon
Diego Bosco
Domenico Trombetta

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1744377

549 views

Original Research

Published on 05 Jan 2026

Natural product extracts for ischemic stroke: a methodological evaluation and meta-epidemiological analysis

in Ethnopharmacology

Sijin Wang
Minghui Zhang
Yao Lu
Peipei Du
Ziwen Xu
Xu Pang
Jierong Gao
Li Li
Chi Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1730699

925 views

Original Research

Published on 05 Jan 2026

Wound healing and photodynamic potential of Adiantum capillus-veneris L. (Pteridaceae): an evaluation of the cellular effects and molecular insights

in Ethnopharmacology

Linru Mou
Banaz Jalil
Francesca Scotti
Majella E. Lane
Bernd L. Fiebich
Lu Sun
Caroline Maake
Michael Heinrich

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1729572

932 views

Original Research

Published on 02 Jan 2026

Cedrol ameliorates inflammatory bowel disease via mitochondrial biogenesis, gut microbiota restoration, and intestinal barrier repair

in Ethnopharmacology

Mo-Rong Xu
Chia-Hsin Lin
Chung-Hsuan Wang
Sheng-Yang Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1619537

1,085 views

Systematic Review

Published on 02 Jan 2026

Efficacy and safety of Chinese herbal medicine for metabolic conditions: a systematic review and meta-analysis of randomised controlled trials

in Ethnopharmacology

Yinglin Liang
Hongshen Yu
Jie Ren
Jiayi Ren
Guanlin Chen
Yikai Zhang
Yefeng Cai
Xiaojia Ni

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1644950

1,616 views

Systematic Review

Published on 02 Jan 2026

Effects of modified Soyo-san (Xiao-yao-san, Shoyo-san) combined with antidepressants on post-stroke depression and functional recovery: a systematic review and meta-analysis

in Ethnopharmacology

Jeongrim Bak
Hyowon Jin
Jong-Min Yun
Jungtae Leem

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1651831

963 views

Review

Published on 02 Jan 2026

Evidence-based production framework for herbal medicine regulation in Indonesia

in Ethnopharmacology

Mohamad Kashuri
Taruna Ikrar
Sutriyo
Abdul Mun’im
Arry Yanuar

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1730273

1,435 views

Review

Accepted on 30 Dec 2025

Pharmacological Advances in Multi-Targeted Strategies for Type 2 Diabetes Mellitus: A Systematic Perspective Based on Traditional Chinese Medicine

in Ethnopharmacology

Yanli Zhao
Jiabao Liao
Panpan Pang
JingYuan Li
Suocai Su
Mengqiu Shao
Weibo Wen
Furong Xu

Frontiers in Pharmacology

253 views

Systematic Review

Accepted on 19 Dec 2025

Glycyrrhizic acid and glycyrrhetinic acid, natural products of Glycyrrhiza uralensis Fisch.: pharmacological and biological activities, pharmacokinetics, toxicological effects, and clinical applications to diseases

in Ethnopharmacology

HUA ZHANG
Chun-li Wu
Ruoyu Chao
Xiang-yu Zhao
Yan-wei Zhang
Qinwei Fu
Qinxiu Zhang
Jianlin WU

Frontiers in Pharmacology

346 views

Review

Published on 19 Dec 2025

Recent advances in natural polysaccharides for type 2 diabetes management: sources, structural characteristics, and mechanistic insights

in Ethnopharmacology

Zexiang Liu
Hanlong Wang
Xiujuan Gong
Xiao Jiang
Kangyi Yang
Linfang Jiang
Zhihui Wang
Qiaozhen Tong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1705122

1,515 views

Systematic Review

Published on 19 Dec 2025

Effectiveness and safety of Ayurvedic intervention in essential hypertension: a systematic review with meta-analysis

in Ethnopharmacology

Saylee Deshmukh
Kuldeep Choudhary
Azeem Ahmad
Govind Reddy
B. C. S. Rao
Narayanam Srikanth
Rabinarayan Acharya

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1695614

2,837 views

Clinical Trial

Published on 19 Dec 2025

Effects and safety of a CBD-rich Cannabis sativa oil in knee osteoarthritis: a double-blind, randomized, placebo-controlled trial – CANOA – cannabis for osteoarthritis

in Ethnopharmacology

Andrés Mojoli
Osvaldo Haider
Yasmin Fakih
Maria Victoria Luz Gonçalves
Bruno Zepeda Rojas
Giovanna Xaia
Emanuelly Krefta
Maíra Assunção Bicca
Thiago Lopes de Mari
Charles Francisco Ferreira

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1657065

2,159 views

Mini Review

Published on 19 Dec 2025

Abhraka Bhasma (mica based nanomedicine): an ayurvedic herbomineral perspective in breast cancer management

in Ethnopharmacology

Dhanya Soman Pillai
Amarnath Karavettekudy Ranjit

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1656846

1,650 views

Original Research

Published on 19 Dec 2025

Emodin and physcion alleviate cholestatic liver injury by targeting FXR: hepatoprotective components identified in processed Polygonum multiflorum Thunb. using a comprehensive two-dimensional biochromatography system

in Ethnopharmacology

Zhihui Li
Yanqiu Gu
Jianbo Yang
Shaozhan Wang
Shengnan Li
Panpan Chen
Ru Yao
Fangbin Liu
Ying Wang
Rong Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1706401

1,603 views

Systematic Review

Published on 18 Dec 2025

Synergistic antitumor effects of astragalus polysaccharide: a preclinical systematic review and meta-analysis

in Ethnopharmacology

Ruo Zhang
Qian Yang
Zhi Chen
Jianming Huang
Guonan Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1672450

1,622 views

Original Research

Published on 18 Dec 2025

A warming-yang herbal decoction protects against high-altitude hypoxia–induced osteoblast injury through modulation of HIF-1 signaling

in Ethnopharmacology

Xuehai Liu
Yaqian Qi
Rui Zhao
Binkui Jia
Xilin Lei
Hongfan Li
Di Wang
Haoling Zhang
Wei Wang
Zhijing Song

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1673146

1,216 views

Original Research

Published on 18 Dec 2025

Anti-inflammatory effect of a pimarane diterpenoid isolated from Nepeta adenophyta Hedge based on a network analysis approach and experimental assessment

in Ethnopharmacology

Wei Zhao
Meng Li
Chuanqing Jia
Iftikhar Ali
Long Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1652902

1,149 views

Original Research

Published on 18 Dec 2025

Harnessing natural terpenes via PEGylated mucoadhesive vesicles for improved urinary bladder delivery: from in vitro evaluation to in vivo assessment

in Ethnopharmacology

Hayder A. Hammoodi
Rofida Albash
Mohammed I. A. Hamed
Khaled M. Darwish
Amira B. Kassem
Asmaa Saleh
Jawaher Abdullah Alamoudi
Noha M. Badawi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1685423

760 views

Original Research

Accepted on 17 Dec 2025

Benefit-risk Assessment of the use of toxic botanical drugs in superiority field: A case study on Aconitum carmichaeli Debx

in Ethnopharmacology

Xiaomeng Zhang
Bing Zhang
Jintao Lyv
Zhijian Lin
Xinlong Liu

Frontiers in Pharmacology

160 views

Review

Accepted on 16 Dec 2025

Harnessing Curcumin in Oral Medicine: Mechanisms, Therapeutic Potential, and Future Innovations

in Ethnopharmacology

Chengchen Hu
Shengguo Wang
Zhi Gao
Maofeng Qing
Lian Tan
Lu Yang
Fang Li

Frontiers in Pharmacology

428 views

Original Research

Published on 16 Dec 2025

Integrated gut microbiota and metabolomics analysis reveals the antitumor effects of ergosta-4,6,8(14),22-tetraen-3-one purified from the medicinal fungus pholiota adiposa in tumor-bearing mice

in Ethnopharmacology

Boyuan Liu
Junsen Qin
Shan Zheng
Jiaxin Zhang
Xuemei Hu
Xiaoyan Wang
Yan Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1653035

1,285 views

5,871 articles

articles

Phytochemical characterization and pharmacological evaluation of aerial and root parts of Dalea pazensis Rusby [Fabaceae]

A critical review of systematic reviews and meta-analyses of curcumin for knee osteoarthritis

Comparison of granule and traditional decoction of Gancao Xiexin for cold-heat complex pattern recurrent oral ulcer: a randomized controlled trial

Harnessing red grape pomace extract for sustainable broad-spectrum photoprotection in a reconstructed human epidermis model

Natural product extracts for ischemic stroke: a methodological evaluation and meta-epidemiological analysis

Wound healing and photodynamic potential of Adiantum capillus-veneris L. (Pteridaceae): an evaluation of the cellular effects and molecular insights

Cedrol ameliorates inflammatory bowel disease via mitochondrial biogenesis, gut microbiota restoration, and intestinal barrier repair

Efficacy and safety of Chinese herbal medicine for metabolic conditions: a systematic review and meta-analysis of randomised controlled trials

Effects of modified Soyo-san (Xiao-yao-san, Shoyo-san) combined with antidepressants on post-stroke depression and functional recovery: a systematic review and meta-analysis

Evidence-based production framework for herbal medicine regulation in Indonesia

Pharmacological Advances in Multi-Targeted Strategies for Type 2 Diabetes Mellitus: A Systematic Perspective Based on Traditional Chinese Medicine

Glycyrrhizic acid and glycyrrhetinic acid, natural products of Glycyrrhiza uralensis Fisch.: pharmacological and biological activities, pharmacokinetics, toxicological effects, and clinical applications to diseases

Recent advances in natural polysaccharides for type 2 diabetes management: sources, structural characteristics, and mechanistic insights

Effectiveness and safety of Ayurvedic intervention in essential hypertension: a systematic review with meta-analysis

Effects and safety of a CBD-rich Cannabis sativa oil in knee osteoarthritis: a double-blind, randomized, placebo-controlled trial – CANOA – cannabis for osteoarthritis

Abhraka Bhasma (mica based nanomedicine): an ayurvedic herbomineral perspective in breast cancer management

Emodin and physcion alleviate cholestatic liver injury by targeting FXR: hepatoprotective components identified in processed Polygonum multiflorum Thunb. using a comprehensive two-dimensional biochromatography system

Synergistic antitumor effects of astragalus polysaccharide: a preclinical systematic review and meta-analysis

A warming-yang herbal decoction protects against high-altitude hypoxia–induced osteoblast injury through modulation of HIF-1 signaling

Anti-inflammatory effect of a pimarane diterpenoid isolated from Nepeta adenophyta Hedge based on a network analysis approach and experimental assessment

Harnessing natural terpenes via PEGylated mucoadhesive vesicles for improved urinary bladder delivery: from in vitro evaluation to in vivo assessment

Benefit-risk Assessment of the use of toxic botanical drugs in superiority field: A case study on Aconitum carmichaeli Debx

Harnessing Curcumin in Oral Medicine: Mechanisms, Therapeutic Potential, and Future Innovations

Integrated gut microbiota and metabolomics analysis reveals the antitumor effects of ergosta-4,6,8(14),22-tetraen-3-one purified from the medicinal fungus pholiota adiposa in tumor-bearing mice