Frontiers in Pharmacology | Ethnopharmacology

Mini Review

Published on 11 Jun 2025

Protective effects of medicinal plant-derived metabolites on slow transit constipation via the ENS-ICC-SMC pathway

in Ethnopharmacology

Zu Gao
Liwen Fu
Wenjun Bai
Junwei Liang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1598806

741 views

Original Research

Published on 11 Jun 2025

Polymethoxyflavones extracted from Bauhinia championii alleviate LPS-induced acute lung injury by ameliorating endoplasmic reticulum stress

in Ethnopharmacology

Yuanyuan Li
Xiaolan Yang
Wenjing Ye
Junsong Jing
Ranran Chen
Lianhao Wu
Zhenqiang You
Sheng Zhang
Jing Shi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1544916

678 views

Original Research

Accepted on 10 Jun 2025

Red Yeast Rice Extract Improves Lipid Metabolism by Modulating Gut Microbiota in High-Fat Diet Mice

in Ethnopharmacology

Peng Hu
Li Zhang
Hongtao Hu
Di Wang
Jenny Chan
Jinghuan Xiao
Hang Wu
Luming Qi
Kaihua Qin
Xiaohong Zuo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1608582

174 views

Original Research

Accepted on 10 Jun 2025

Esculetin inhibited PI3K/Akt/mTOR pathway and enhances anti-colorectal cancer activity via binding to ENO1

in Ethnopharmacology

Jianing Ma
Shulipan Mulat
Miaomiao Zhang
Nabi Xinhua
Weiyi Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1627114

147 views

Original Research

Published on 10 Jun 2025

Integrated metabolomic, transcriptomic and network analysis elucidates therapeutic mechanisms of Ganoderma lucidum spore oil against granulomatous pulmonary nodules

in Ethnopharmacology

Ya Liu
Wendong Xu
Kexin Wang
Zhiye You
Xiaohong Chen
Huihui Ti
Xiaoli Liang
Lin Cao
Hongfei Cai
Juyan Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1612043

1,187 views

Original Research

Published on 10 Jun 2025

Schaftoside contributed to anti-inflammatory activity of Clinacanthus nutans extract in lipopolysaccharide-induced RAW 264.7 cells

in Ethnopharmacology

Saruda Thongyim
Pachara Sattayawat
Wittaya Pongamornkul
Siriphorn Jangsutthivorawat
Yingmanee Tragoolpua
Aussara Panya

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1584620

699 views

Review

Published on 10 Jun 2025

Gut microbiota modulation by Traditional Chinese Medicine: a translational strategy for metabolic dysfunction-associated steatotic liver disease

in Ethnopharmacology

Ting Zhou
Ziwen Jin
Rilei Jiang
Weiwei Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1600439

998 views

Original Research

Accepted on 09 Jun 2025

Ethyl acetate extract of Knoxia roxburghii (Rubiaceae) down-regulates ECHDC1, CAMK2D, DDB1, UBA6, BIRC6, and HK1 proteins and ameliorates the symptoms of diabetes mellitus

in Ethnopharmacology

Xinge Wang
Xiaoqiao Tian
Yang Xu
Rong Li
Gusha Qumo
Jingping Li
Niman Bao
Maoru Li
Bin Qiu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1587858

165 views

Review

Published on 09 Jun 2025

Clinical and basic research advances on Jinlong capsule for the prevention and treatment of liver cancer

in Ethnopharmacology

Liyuan Lv
Simeng Ren
Zunyi Zhang
Hongsheng Lin
Jie Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1522945

922 views

Original Research

Published on 09 Jun 2025

Gandouling ameliorates Wilson’s disease-associated liver fibrosis in mice with associated faecal microbiome and metabolome remodeling

in Ethnopharmacology

Lulu Tang
Wei Dong
Danqing Liu
Chenling Zhao
Jie Chen
Yuya Wen
Jingyu Zeng
Ting Dong
Wenming Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1586171

854 views

Review

Published on 09 Jun 2025

Targeting the gut microbiota and lipid metabolism: potential mechanisms of natural products for the treatment of non-alcoholic fatty liver disease

in Ethnopharmacology

Yutian Zhang
Tianlin Wang
Junquan Han
Jielin Song
Chaoshuai Yang
Lei Liang
Huizhen Li
Hong Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1610498

1,141 views

Original Research

Published on 09 Jun 2025

Astragalus membranaceus extract attenuates ulcerative colitis by integrating multiomics and the PI3K/AKT signaling pathway

in Ethnopharmacology

Jiaying Zhu
Chenhuan Shentu
Qingling Meng
Sen Fan
Yunjia Tang
Mingjiang Mao
Xiaofeng Yuan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1585748

1,037 views

Original Research

Published on 06 Jun 2025

Hydroxysafflor yellow A alleviates oxidative stress and inflammatory damage in the livers of mice with nonalcoholic fatty liver disease and modulates gut microbiota

in Ethnopharmacology

Liang Wu
Xueyun Dong
Wen Sun
Tan Jiajun
Asmaa Ali
Jiayuan He
Pingping Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1568608

1,201 views

Original Research

Published on 06 Jun 2025

Efficacy of indigo naturalis nanofibrous patches in the treatment of chronic plaque psoriasis: a 4-week prospective, randomized, semi-compartmental paired, positive drug-controlled trial

in Ethnopharmacology

Yuechun Zhao
Jiaqi Li
Ningxin Zhang
Mingyue Liu
Pengyu Wang
Ning Li
Ruodan Xu
Ping Song

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1595019

1,041 views

Review

Published on 06 Jun 2025

Regulation of transient receptor potential ankyrin 1 by traditional Chinese medicine drugs and their active ingredients

in Ethnopharmacology

Yunlong Fang
Chunxin Lei
Zihan Wang
Longxiao Liu
Yanyu Chen
Feng Chen
Jingxuan Li
Zhikun Tu
Qingwen Tao
Yuan Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1604765

1,101 views

Original Research

Accepted on 05 Jun 2025

The Phenology of Epilobium hirsutum L.: Assessing Marker Compounds Variability of a Pharmaceutically Important Plant Remedy

in Ethnopharmacology

Olha Mykhailenko
Banaz Jalil
Zigmantas Gudžinskas
Kateryna Uminska
Liudas Ivanauskas
Michael Heinrich

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1602819

142 views