Frontiers in Pharmacology | Experimental Pharmacology and Drug Discovery

Review

Published on 30 Oct 2024

Targeting ferroptosis: a novel therapeutic strategy for the treatment of retinal diseases

in Experimental Pharmacology and Drug Discovery

Xiao-Dan Hao
Wen-Hua Xu
Xiaoping Zhang
Junqiang Xue

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1489877

1,681 views

Review

Published on 30 Oct 2024

The regulating role of galectin-9 in immune cell populations

in Experimental Pharmacology and Drug Discovery

Zhanqi Cao
Ping Leng
Hanlin Xu
Xiangpeng Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1462061

1,002 views
1 citation

Original Research

Published on 30 Oct 2024

Novel N-phenyl-2-(aniline) benzamide hydrochloride salt development for colon cancer therapy

in Experimental Pharmacology and Drug Discovery

Yan Peng
Ying Peng
Wei Zhang
Siyi Zhang
Huiqian Peng
Zhen Li
Bo Li
Linyi Liu
Linsheng Zhuo
Zhen Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1452904

623 views

Original Research

Published on 30 Oct 2024

Identification of novel SARS-CoV-2 3CLpro inhibitors by molecular docking, in vitro assays, molecular dynamics simulations and DFT analyses

in Experimental Pharmacology and Drug Discovery

Keli Zong
Chaochun Wei
Wei Li
Jiajun Ruan
Susu Zhang
Jingjing Li
Xiaojing Liu
Xu Zhao
Ruiyuan Cao
Hong Yan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1494953

911 views
1 citation

Original Research

Published on 30 Oct 2024

Structure–function relationship of dynorphin B variants using naturally occurring amino acid substitutions

in Experimental Pharmacology and Drug Discovery

Luca Zangrandi
Barbara Fogli
Anna Mutti
René Staritzbichler
Victoria Most
Peter W. Hildebrand
Regine Heilbronn
Christoph Schwarzer

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1484730

648 views
1 citation

Original Research

Published on 29 Oct 2024

Anti-inflammatory effects of para-quinone methide derivatives on ulcerative colitis

in Experimental Pharmacology and Drug Discovery

Yue Qiu
Xin Li
Xu Zhang
Xiaotong Wang
Xuekun Wang
Jie Yang
Guoyun Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1474678

843 views

Original Research

Published on 28 Oct 2024

Effects of fermented Arctium lappa L. root by Lactobacillus casei on hyperlipidemic mice

in Experimental Pharmacology and Drug Discovery

MingJu Chen
Yuxiao Wu
Hongxuan Yang
Tianfeng Liu
Tongkun Han
Wangqiang Dai
Junyue Cen
Fan Ouyang
Jingjing Chen
Jianxin Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1447077

928 views

Original Research

Published on 25 Oct 2024

Alisol A inhibits and stabilizes atherosclerotic plaques by protecting vascular endothelial cells

in Experimental Pharmacology and Drug Discovery

Yang Ma
Dingzhong Song
Jie Yuan
Wusi Hao
Jianqiang Xi
Chunping Yuan
Zhihong Cheng

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1493948

743 views

Original Research

Published on 24 Oct 2024

Deciphering quinazoline derivatives’ interactions with EGFR: a computational quest for advanced cancer therapy through 3D-QSAR, virtual screening, and MD simulations

in Experimental Pharmacology and Drug Discovery

Sirajudheen Anwar
Jowaher Alanazi
Nafees Ahemad
Shafaq Raza
Tahir Ali Chohan
Hammad Saleem

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1399372

1,037 views
1 citation

Review

Published on 24 Oct 2024

Recent advances in the structures and bioactivities of benzopyrans derived from marine fungi: a review

in Experimental Pharmacology and Drug Discovery

Yidan Xi
Huannan Wang
Lixiang Sun
Xueyang Ma
Shuncun Zhang
Zhen Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1482316

860 views

Methods

Published on 24 Oct 2024

Effect of 5% lidocaine-medicated plaster in preventing chronic postsurgical pain after knee replacement: protocol for a randomized double-blind placebo-controlled trial

in Experimental Pharmacology and Drug Discovery

Junpeng Yuan
Huichan Xu
Jiongjiong Guo
Yan Li
Youjia Yu
Xiaohong Jin

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1486217

6,972 views

Original Research

Published on 24 Oct 2024

Characteristics of adverse reactions of three anti-glioma drugs in WHO-VigiAccess

in Experimental Pharmacology and Drug Discovery

Huadong Ke
Zicheng Zhang
Zhao Yu
Baiquan Zhang
Rui Chen
Qiang Zhou
Qian Guo
Xiaohui Lou

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1485067

1,141 views

Original Research

Published on 23 Oct 2024

De novo design of mIDH1 inhibitors by integrating deep learning and molecular modeling

in Experimental Pharmacology and Drug Discovery

Dingkang Sun
Lulu Xu
Mengfan Tong
Zhao Wei
Weitong Zhang
Jialong Liang
Xueying Liu
Yuwei Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1491699

748 views

Opinion

Published on 23 Oct 2024

The enigma of small heat shock protein phosphorylation

in Experimental Pharmacology and Drug Discovery

Matthias Gaestel

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1486245

549 views

Original Research

Published on 23 Oct 2024

Antimutagenic and anticoagulant therapeutic effects of Ag/Ag2O nanoparticles from Olea europaea leaf extract: mitigating metribuzin-induced hepato-and nephrotoxicity

in Experimental Pharmacology and Drug Discovery

Manel Azzi
Ibtissam Laib
Abderrhmane Bouafia
Ifriqya Medila
Ali Tliba
Salah Eddine Laouini
Huda Alsaeedi
David Cornu
Mikhael Bechelany
Ahmed Barhoum

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1485525

1,300 views

Original Research

Published on 23 Oct 2024

Clopidogrel ameliorates high-fat diet-induced hepatic steatosis in mice through activation of the AMPK signaling pathway and beyond

in Experimental Pharmacology and Drug Discovery

Ting Tai
Yuan-Yuan Shao
Yu-Qi Zheng
Li-Ping Jiang
Hao-Ru Han
Na Yin
Hao-Dong Li
Jin-Zi Ji
Qiong-Yu Mi
Li Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1496639

2,140 views

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Articles

Targeting ferroptosis: a novel therapeutic strategy for the treatment of retinal diseases

The regulating role of galectin-9 in immune cell populations

Novel N-phenyl-2-(aniline) benzamide hydrochloride salt development for colon cancer therapy

Identification of novel SARS-CoV-2 3CLpro inhibitors by molecular docking, in vitro assays, molecular dynamics simulations and DFT analyses

Structure–function relationship of dynorphin B variants using naturally occurring amino acid substitutions

Anti-inflammatory effects of para-quinone methide derivatives on ulcerative colitis

Effects of fermented Arctium lappa L. root by Lactobacillus casei on hyperlipidemic mice

Alisol A inhibits and stabilizes atherosclerotic plaques by protecting vascular endothelial cells

Deciphering quinazoline derivatives’ interactions with EGFR: a computational quest for advanced cancer therapy through 3D-QSAR, virtual screening, and MD simulations

Recent advances in the structures and bioactivities of benzopyrans derived from marine fungi: a review

Effect of 5% lidocaine-medicated plaster in preventing chronic postsurgical pain after knee replacement: protocol for a randomized double-blind placebo-controlled trial

Characteristics of adverse reactions of three anti-glioma drugs in WHO-VigiAccess

De novo design of mIDH1 inhibitors by integrating deep learning and molecular modeling

The enigma of small heat shock protein phosphorylation

Antimutagenic and anticoagulant therapeutic effects of Ag/Ag2O nanoparticles from Olea europaea leaf extract: mitigating metribuzin-induced hepato-and nephrotoxicity

Clopidogrel ameliorates high-fat diet-induced hepatic steatosis in mice through activation of the AMPK signaling pathway and beyond