Frontiers in Pharmacology | Experimental Pharmacology and Drug Discovery

Original Research

Published on 21 Aug 2024

The therapeutic targets and signaling mechanisms of ondansetron in the treatment of critical illness in the ICU

in Experimental Pharmacology and Drug Discovery

Lili Tao
Zhenhui Zhang
Chuang Li
Minxuan Huang
Ping Chang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1443169

2,133 views

Original Research

Published on 20 Aug 2024

The role of GZMA as a target of cysteine and biomarker in Alzheimer’s disease, pelvic organ prolapse, and tumor progression

in Experimental Pharmacology and Drug Discovery

Yan Li
Zhuo Wang
Min Kong
Yuanyuan Yong
Xin Yang
Chongdong Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1447605

1,512 views

Brief Research Report

Published on 19 Aug 2024

Evaluation of sunobinop for next-day residual effects in healthy participants

in Experimental Pharmacology and Drug Discovery

Alessandra Cipriano
Ram P. Kapil
Mingyan Zhou
Manjunath S. Shet
Stephen C. Harris
Glen Apseloff
Garth T. Whiteside

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1432902

735 views

Original Research

Published on 19 Aug 2024

Astaxanthin activated the SLC7A11/GPX4 pathway to inhibit ferroptosis and enhance autophagy, ameliorating dry eye disease

in Experimental Pharmacology and Drug Discovery

Chenting Hou
Jie Xiao
Youhai Wang
Xinghui Pan
Kangrui Liu
Kang Lu
Qing Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1407659

2,358 views
1 citation

Original Research

Published on 16 Aug 2024

Novel therapeutic targets for primary open-angle glaucoma identified through multicenter proteome-wide mendelian randomization

in Experimental Pharmacology and Drug Discovery

Weichen Yuan
Jun Li
Shang Gao
Wei Sun
Fangkun Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1428472

2,756 views

Mini Review

Published on 15 Aug 2024

Preparation strategies of mussel-inspired chitosan-based biomaterials for hemostasis

in Experimental Pharmacology and Drug Discovery

Guihua Cui
Xiaoyu Guo
Li Deng

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1439036

1,599 views
1 citation

Systematic Review

Published on 15 Aug 2024

Diagnostic lncRNA high expression for liver patients prognosis and medication guidance: a systematic review and meta-analysis

in Experimental Pharmacology and Drug Discovery

Hengzhou Zhu
Haoyan Chen
Xiaodan Zhu
Baonan Zhang
Chunhui Jin

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1462512

813 views

Original Research

Published on 13 Aug 2024

Investigation of METTL3 as an inhibitor of kanamycin-induced ototoxicity via stress granule formation

in Experimental Pharmacology and Drug Discovery

Yan Wu
Yu-Yu Huang
Lu-Yao Wang
Yan Yang
Fei-Lun Cui
Shu-Na Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1430162

1,028 views

Review

Published on 12 Aug 2024

Unlocking the full potential of rare disease drug development: exploring the not-for-profit sector’s contributions to drug development and access

in Experimental Pharmacology and Drug Discovery

Stefano Vavassori
Sean Russell
Celeste Scotti
Stefano Benvenuti

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1441807

2,024 views
1 citation

Review

Published on 12 Aug 2024

Osteoporosis treatment: current drugs and future developments

in Experimental Pharmacology and Drug Discovery

Ya-jing Chen
Li-hua Jia
Tao-hong Han
Zhi-hui Zhao
Jian Yang
Jun-ping Xiao
Hong-Jun Yang
Ke Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1456796

7,296 views
3 citations

Original Research

Published on 09 Aug 2024

The structural characterization and UV-protective properties of an exopolysaccharide from a Paenibacillus isolate

in Experimental Pharmacology and Drug Discovery

Xiaodong Xu
Zhao Ding
Chunlin Pu
Changchang Kong
Shijunyin Chen
Weiling Lu
Jianfa Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1434136

2,050 views
1 citation

Editorial

Published on 09 Aug 2024

Editorial: Advances in novel pharmacotherapeutics and drug discovery: computational, experimental, translational, and clinical models

in Experimental Pharmacology and Drug Discovery

Cristian Sandoval
Francisco Torrens
Vanessa Souza-Mello
Jorge Farías

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1465835

574 views

Correction

Published on 09 Aug 2024

Corrigendum: Pharmacological effects of monoterpene carveol on the neuromuscular system of nematodes and mammals

in Experimental Pharmacology and Drug Discovery

Maja Stojković
Zoran Todorović
Dragana Protic
Strahinja Stevanovic
Dragana Medić
Claude L. Charvet
Elise Courtot
Djordje S. Marjanović
Jelena Nedeljković Trailović
Saša M. Trailović

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1466575

561 views

Editorial

Published on 08 Aug 2024

Editorial: Model organisms in experimental pharmacology and drug discovery 2023: rodent, worm and zebrafish models

in Experimental Pharmacology and Drug Discovery

Kuo-Hui Su
Priscilla Kolibea Mante
Pedro Xavier-Elsas

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1462972

685 views

Original Research

Published on 08 Aug 2024

Identification of miRNAs related to osteoporosis by high-throughput sequencing

in Experimental Pharmacology and Drug Discovery

Jiachun Huang
Haolin Yang
Shuang Chai
Yanping Lin
Zhihai Zhang
Hongxing Huang
Lei Wan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1451695

1,112 views
1 citation

Systematic Review

Published on 08 Aug 2024

Advancing biomedical applications: an in-depth analysis of silver nanoparticles in antimicrobial, anticancer, and wound healing roles

in Experimental Pharmacology and Drug Discovery

Himanshu Jangid
Sudhakar Singh
Piyush Kashyap
Avtar Singh
Gaurav Kumar

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1438227

4,181 views
12 citations

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Articles

The therapeutic targets and signaling mechanisms of ondansetron in the treatment of critical illness in the ICU

The role of GZMA as a target of cysteine and biomarker in Alzheimer’s disease, pelvic organ prolapse, and tumor progression

Evaluation of sunobinop for next-day residual effects in healthy participants

Astaxanthin activated the SLC7A11/GPX4 pathway to inhibit ferroptosis and enhance autophagy, ameliorating dry eye disease

Novel therapeutic targets for primary open-angle glaucoma identified through multicenter proteome-wide mendelian randomization

Preparation strategies of mussel-inspired chitosan-based biomaterials for hemostasis

Diagnostic lncRNA high expression for liver patients prognosis and medication guidance: a systematic review and meta-analysis

Investigation of METTL3 as an inhibitor of kanamycin-induced ototoxicity via stress granule formation

Unlocking the full potential of rare disease drug development: exploring the not-for-profit sector’s contributions to drug development and access

Osteoporosis treatment: current drugs and future developments

The structural characterization and UV-protective properties of an exopolysaccharide from a Paenibacillus isolate

Editorial: Advances in novel pharmacotherapeutics and drug discovery: computational, experimental, translational, and clinical models

Corrigendum: Pharmacological effects of monoterpene carveol on the neuromuscular system of nematodes and mammals

Editorial: Model organisms in experimental pharmacology and drug discovery 2023: rodent, worm and zebrafish models

Identification of miRNAs related to osteoporosis by high-throughput sequencing

Advancing biomedical applications: an in-depth analysis of silver nanoparticles in antimicrobial, anticancer, and wound healing roles