Frontiers in Pharmacology | Experimental Pharmacology and Drug Discovery

Original Research

Published on 06 Aug 2024

Differing temperature dependencies of functional homologs zebrafish Abcb4 and human ABCB1

in Experimental Pharmacology and Drug Discovery

Till Luckenbach
Kathleen Burkhardt-Medicke

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1426040

780 views

Mini Review

Published on 02 Aug 2024

The regulatory mechanisms of cerium oxide nanoparticles in oxidative stress and emerging applications in refractory wound care

in Experimental Pharmacology and Drug Discovery

Lijun Yi
Lijian Yu
Shouying Chen
Delong Huang
Cheng Yang
Hairui Deng
Yiheng Hu
Hui Wang
Zhongjian Wen
Yiren Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1439960

2,344 views
3 citations

Original Research

Published on 02 Aug 2024

Optimization of culture conditions for endophytic bacteria in mangrove plants and isolation and identification of bacteriocin

in Experimental Pharmacology and Drug Discovery

Jinju Peng
Xingpeng Xie
Tingli Fan
Haotian Ma
Yang Li
Shuaishuai Luo
Mengbo Yu
Yuexia Ding
Yi Ma

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1429423

1,108 views
1 citation

Original Research

Published on 02 Aug 2024

Improvement of solubility, dissolution, and bioavailability of phenytoin intercalated in Mg-Al layered double hydroxide

in Experimental Pharmacology and Drug Discovery

Rehab Anwar Bakr
Sabna Kotta
Hibah Mubarak Aldawsari
Lubna Y. Ashri
Shaimaa M. Badr-Eldin
Heba Eltahir
Sameh A. Ahmed
Yaser M. Alahmadi
Mekky Abouzied

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1440361

1,584 views

Original Research

Published on 02 Aug 2024

Oncoproteins E6 and E7 upregulate topoisomerase I to activate the cGAS-PD-L1 pathway in cervical cancer development

in Experimental Pharmacology and Drug Discovery

Ying Luo
Mengda Niu
Yanfei Liu
Miaochang Zhang
Yuanyuan Deng
Dan Mu
Junfen Xu
Shiyuan Hong

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1450875

1,545 views
3 citations

Original Research

Published on 01 Aug 2024

Evodiamine suppresses endometriosis development induced by early EBV exposure through inhibition of ERβ

in Experimental Pharmacology and Drug Discovery

Junling Wang
Yuanqi Liang
Xiaoru Liang
Huijuan Peng
Yongxia Wang
Mingtao Xu
Xuefang Liang
Helen Yao
Xiaohan Liu
Liqin Zeng

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1426660

1,526 views
1 citation

Original Research

Published on 01 Aug 2024

Hydrogen sulfide protects against toxicant acrolein-induced ferroptotic cell death in Sertoli cells

in Experimental Pharmacology and Drug Discovery

Zhimin Mao
Qun Ji
Ping Chen
Kun Zhong
Xuhui Zeng

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1440147

1,361 views

Review

Published on 31 Jul 2024

Therapeutic potential of Chinese medicinal herbs stimulating osteogenic differentiation of bone marrow-derived mesenchymal stem cells in osteoporosis

in Experimental Pharmacology and Drug Discovery

Hui Wang
Kai Shan
Yan Li
Sinuo Wu
Chunman Zhou
Shan Tao
Meijuan Wang
Xiaochun Kang
Liang Zhou
Zhongxi Lyu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1423555

2,080 views

Original Research

Published on 30 Jul 2024

Naringin and temozolomide combination suppressed the growth of glioblastoma cells by promoting cell apoptosis: network pharmacology, in-vitro assays and metabolomics based study

in Experimental Pharmacology and Drug Discovery

Priya Bisht
Surendra Rajit Prasad
Khushboo Choudhary
Ruchi Pandey
Dande Aishwarya
Vulli Aravind
Peraman Ramalingam
Ravichandiran Velayutham
Nitesh Kumar

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1431085

3,622 views
1 citation

Original Research

Published on 30 Jul 2024

Pharmacokinetics and tissue distribution of LN002, a new compound alternative oxidase inhibitor against Cryptosporidium in rats

in Experimental Pharmacology and Drug Discovery

Minglang Ma
Yongxiang Zhang
Yanjun Fang
Yixing Lu
Huiguo Huang
Zhenling Zeng
Dongping Zeng

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1413872

815 views
1 citation

Editorial

Published on 30 Jul 2024

Editorial: The culprit behind some diseases: overexpression/hyperactivity of G6PD

in Experimental Pharmacology and Drug Discovery

Muhammet Karaman
N. Nuray Ulusu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1459741

820 views

Original Research

Published on 29 Jul 2024

Machine learning-based prediction model for the efficacy and safety of statins

in Experimental Pharmacology and Drug Discovery

Yu Xiong
Xiaoyang Liu
Qing Wang
Li Zhao
Xudong Kong
Chunhe Da
Zuohuan Meng
Leilei Qu
Qinfang Xia
Lihong Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1334929

1,907 views

Original Research

Published on 29 Jul 2024

Soloxolone para-methylanilide effectively suppresses aggressive phenotype of glioblastoma cells including TGF-β1-induced glial-mesenchymal transition in vitro and inhibits growth of U87 glioblastoma xenografts in mice

in Experimental Pharmacology and Drug Discovery

Kirill V. Odarenko
Aleksandra V. Sen’kova
Oksana V. Salomatina
Oleg V. Markov
Nariman F. Salakhutdinov
Marina A. Zenkova
Andrey V. Markov

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1428924

1,987 views
2 citations

Original Research

Published on 29 Jul 2024

Melatonin supplementation counteracts fiber loss in knee ligaments of diabetes-induced rats

in Experimental Pharmacology and Drug Discovery

Olga Adamska
Artur Wnuk
Agnieszka Kamińska
Małgorzata Poniatowska
Bartosz Maciąg
Maciej Kamiński
Artur Stolarczyk
Maima Matin
Atanas G. Atanasov
Marcin Łapiński

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1399719

1,883 views

Original Research

Published on 29 Jul 2024

Potential mechanism of Luoshi Neiyi prescription in endometriosis based on serum pharmacochemistry and network pharmacology

in Experimental Pharmacology and Drug Discovery

Lizheng Wu
Shuhong Lin
Yongjun Hu
Shangwen Jing
Bowen Sun
Xiaoxin Chen
Jinjin Jia
Cheng Zeng
Fangli Pei

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1395160

2,419 views

Original Research

Published on 26 Jul 2024

LSD1 inhibition by tranylcypromine hydrochloride reduces alkali burn-induced corneal neovascularization and ferroptosis by suppressing HIF-1α pathway

in Experimental Pharmacology and Drug Discovery

Qian Deng
Yuelan Gao
Yujin Wang
Jiewen Mao
Yulin Yan
Zixian Yang
Yuyu Cong
Yanning Yang
Shanshan Wan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1411513

1,994 views

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Articles

Differing temperature dependencies of functional homologs zebrafish Abcb4 and human ABCB1

The regulatory mechanisms of cerium oxide nanoparticles in oxidative stress and emerging applications in refractory wound care

Optimization of culture conditions for endophytic bacteria in mangrove plants and isolation and identification of bacteriocin

Improvement of solubility, dissolution, and bioavailability of phenytoin intercalated in Mg-Al layered double hydroxide

Oncoproteins E6 and E7 upregulate topoisomerase I to activate the cGAS-PD-L1 pathway in cervical cancer development

Evodiamine suppresses endometriosis development induced by early EBV exposure through inhibition of ERβ

Hydrogen sulfide protects against toxicant acrolein-induced ferroptotic cell death in Sertoli cells

Therapeutic potential of Chinese medicinal herbs stimulating osteogenic differentiation of bone marrow-derived mesenchymal stem cells in osteoporosis

Naringin and temozolomide combination suppressed the growth of glioblastoma cells by promoting cell apoptosis: network pharmacology, in-vitro assays and metabolomics based study

Pharmacokinetics and tissue distribution of LN002, a new compound alternative oxidase inhibitor against Cryptosporidium in rats

Editorial: The culprit behind some diseases: overexpression/hyperactivity of G6PD

Machine learning-based prediction model for the efficacy and safety of statins

Soloxolone para-methylanilide effectively suppresses aggressive phenotype of glioblastoma cells including TGF-β1-induced glial-mesenchymal transition in vitro and inhibits growth of U87 glioblastoma xenografts in mice

Melatonin supplementation counteracts fiber loss in knee ligaments of diabetes-induced rats

Potential mechanism of Luoshi Neiyi prescription in endometriosis based on serum pharmacochemistry and network pharmacology

LSD1 inhibition by tranylcypromine hydrochloride reduces alkali burn-induced corneal neovascularization and ferroptosis by suppressing HIF-1α pathway