Frontiers in Pharmacology | Experimental Pharmacology and Drug Discovery

Original Research

Published on 15 Jul 2024

Detection of muscular system adverse reaction signals in sacubitril/valsartan treatment combined with statins

in Experimental Pharmacology and Drug Discovery

Fukun Zhao
Min Luo
Yuanmin Wang
Mu Su
Fei Tang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1393616

1,175 views

Original Research

Published on 12 Jul 2024

RG7774 (Vicasinabin), an orally bioavailable cannabinoid receptor 2 (CB2R) agonist, decreases retinal vascular permeability, leukocyte adhesion, and ocular inflammation in animal models

in Experimental Pharmacology and Drug Discovery

Uwe Grether
Richard H. Foxton
Sabine Gruener
Claudia Korn
Atsushi Kimbara
Anja Osterwald
Elisabeth Zirwes
Sabine Uhles
Janina Thoele
Nadine Colé

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1426446

3,065 views
5 citations

Editorial

Published on 12 Jul 2024

Editorial: Research and advances on medication for corneal diseases and surgery

in Experimental Pharmacology and Drug Discovery

Nan-Ji Lu
Farhad Hafezi
Carina Koppen
Ioannis M. Aslanides

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1434180

593 views

Editorial

Published on 12 Jul 2024

Editorial: Women in experimental pharmacology and drug discovery 2023

in Experimental Pharmacology and Drug Discovery

Patricia Rijo
Emel Timucin
Maria M. M. Santos
Valeria Bruno

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1439405

525 views

Original Research

Published on 11 Jul 2024

Bioassay-guided isolation of leishmanicidal cucurbitacins from Momordica charantia

in Experimental Pharmacology and Drug Discovery

Maria Carolina Silva Marques
Nídia Cristiane Yoshida
Eduardo Caio Torres-Santos
Fernanda Rodrigues Garcez
Walmir Silva Garcez

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1390715

871 views

Original Research

Published on 11 Jul 2024

Propolis attenuates diabetes-induced testicular injury by protecting against DNA damage and suppressing cellular stress

in Experimental Pharmacology and Drug Discovery

Ahmed M. Ashour

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1416238

1,254 views

Review

Published on 10 Jul 2024

The role of cGAS in epithelial dysregulation in inflammatory bowel disease and gastrointestinal malignancies

in Experimental Pharmacology and Drug Discovery

Anna Ramos
Nazih Bizri
Elizabeth Novak
Kevin Mollen
Sidrah Khan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1409683

1,539 views
2 citations

Original Research

Published on 10 Jul 2024

Anti-hyperglycemic effects of Cissus quadrangularis extract via regulation of gluconeogenesis in type 2 diabetic db/db mice

in Experimental Pharmacology and Drug Discovery

Jeong-Won Kim
Ji-Soo Jeong
Jin-Hwa Kim
Eun-Hye Chung
Chang-Yeop Kim
Dong-Ryung Lee
Bong-Keun Choi
Jong-Hwan Lim
Je-Won Ko
Tae-Won Kim

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1415670

1,934 views

Original Research

Published on 10 Jul 2024

Exploring the mechanisms of Qingdu Fang for the treatment of cervical HR-HPV using UPLC-QTOF-MS, network pharmacology, and cell experimentation

in Experimental Pharmacology and Drug Discovery

Shanyun Wang
Guangru Li
Zhuqiang Wang
Qing Luo
Jianfeng Zeng
Jing Xiao

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1415422

1,186 views

Original Research

Published on 10 Jul 2024

Pharmacokinetic study of Q808 in rhesus monkey using liquid chromatography–tandem mass spectrometry

in Experimental Pharmacology and Drug Discovery

Ning Xiao
Xiang Li
Wei Li
Jialin Zhao
Yingnan Li
Limei Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1433043

763 views

Original Research

Published on 10 Jul 2024

COE targets EphA2 to inhibit vasculogenic mimicry formation induced by hypoxia in hepatocellular carcinoma

in Experimental Pharmacology and Drug Discovery

Jue Chen
Shu-Ying Dai
Su Wu
Meng-Ke Wu
Ke-Ke Yu
Jun-Chi Liu
Jia-Yu Chang
Yan-Qing Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1421470

1,304 views

Editorial

Published on 10 Jul 2024

Editorial: Oral mucosa and disorders: from drug discovery to development and translation

in Experimental Pharmacology and Drug Discovery

Vivek Ghate
Mohammed S. Alqahtani
Harsh Shah
K. M. Veena

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1445126

586 views

Original Research

Published on 08 Jul 2024

Single-cell RNA sequencing uncovers cellular heterogeneity and the progression of heterotopic ossification of the elbow

in Experimental Pharmacology and Drug Discovery

Chi Zhang
Dan Xiao
Li Shu
Maoqi Gong
Xinghua Liu
Xieyuan Jiang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1434146

2,225 views
1 citation

Review

Published on 08 Jul 2024

Cyclophilin inhibition as a strategy for the treatment of human disease

in Experimental Pharmacology and Drug Discovery

Winston T. Stauffer
Asha Z. Goodman
Philippe A. Gallay

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1417945

1,968 views
3 citations

Correction

Published on 08 Jul 2024

Corrigendum: Network pharmacology-based exploration identified the antiviral efficacy of Quercetin isolated from mulberry leaves against enterovirus 71 via the NF-κB signaling pathway

in Experimental Pharmacology and Drug Discovery

Tianrun Liu
Yingyu Li
Lumeng Wang
Xiaomeng Zhang
Yuxuan Zhang
Xuejie Gai
Li Chen
Lei Liu
Limin Yang
Baixin Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1421483

580 views
1 citation

Original Research

Published on 08 Jul 2024

Wogonin protects against bleomycin-induced mouse pulmonary fibrosis via the inhibition of CDK9/p53-mediated cell senescence

in Experimental Pharmacology and Drug Discovery

Libo Wang
Fei Lin
Youli Liu
Wei Li
Qingjie Ding
Xulei Duan
Lin Yang
Zhengyu Bai
Min Zhang
Yuming Guo

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1407891

1,965 views

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Articles

Detection of muscular system adverse reaction signals in sacubitril/valsartan treatment combined with statins

RG7774 (Vicasinabin), an orally bioavailable cannabinoid receptor 2 (CB2R) agonist, decreases retinal vascular permeability, leukocyte adhesion, and ocular inflammation in animal models

Editorial: Research and advances on medication for corneal diseases and surgery

Editorial: Women in experimental pharmacology and drug discovery 2023

Bioassay-guided isolation of leishmanicidal cucurbitacins from Momordica charantia

Propolis attenuates diabetes-induced testicular injury by protecting against DNA damage and suppressing cellular stress

The role of cGAS in epithelial dysregulation in inflammatory bowel disease and gastrointestinal malignancies

Anti-hyperglycemic effects of Cissus quadrangularis extract via regulation of gluconeogenesis in type 2 diabetic db/db mice

Exploring the mechanisms of Qingdu Fang for the treatment of cervical HR-HPV using UPLC-QTOF-MS, network pharmacology, and cell experimentation

Pharmacokinetic study of Q808 in rhesus monkey using liquid chromatography–tandem mass spectrometry

COE targets EphA2 to inhibit vasculogenic mimicry formation induced by hypoxia in hepatocellular carcinoma

Editorial: Oral mucosa and disorders: from drug discovery to development and translation

Single-cell RNA sequencing uncovers cellular heterogeneity and the progression of heterotopic ossification of the elbow

Cyclophilin inhibition as a strategy for the treatment of human disease

Corrigendum: Network pharmacology-based exploration identified the antiviral efficacy of Quercetin isolated from mulberry leaves against enterovirus 71 via the NF-κB signaling pathway

Wogonin protects against bleomycin-induced mouse pulmonary fibrosis via the inhibition of CDK9/p53-mediated cell senescence