Frontiers in Pharmacology | Experimental Pharmacology and Drug Discovery

Original Research

Published on 05 Jul 2024

PTGES2 and RNASET2 identified as novel potential biomarkers and therapeutic targets for basal cell carcinoma: insights from proteome-wide mendelian randomization, colocalization, and MR-PheWAS analyses

in Experimental Pharmacology and Drug Discovery

Qiu-Ju Han
Yi-Pan Zhu
Jing Sun
Xin-Yu Ding
Xiuyu Wang
Qiang-Zhe Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1418560

4,056 views

Correction

Published on 05 Jul 2024

Corrigendum: Anti-inflammatory and antioxidant effects of flavonoid-rich fraction of bergamot juice (BJe) in a mouse model of intestinal ischemia/reperfusion injury

in Experimental Pharmacology and Drug Discovery

Daniela Impellizzeri
Marika Cordaro
Michela Campolo
Enrico Gugliandolo
Emanuela Esposito
Filippo Benedetto
Salvatore Cuzzocrea
Michele Navarra

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1434215

536 views

Review

Published on 04 Jul 2024

The potential application of fermented tea as a drink for regulating bone mass

in Experimental Pharmacology and Drug Discovery

Qiaolu Xu
Yikang Yu
Ke Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1353811

1,665 views

Original Research

Published on 04 Jul 2024

Long Mu Qing Xin mixture improves behavioral performance in spontaneously hypertensive rats (SHR/NCrl) by upregulating catecholamine neurotransmitters in prefrontal cortex and striatum via DRD1/cAMP/PKA-CREB signaling pathway

in Experimental Pharmacology and Drug Discovery

Xuejun Li
Zhen Xiao
Zhiyan Jiang
Wenyan Pu
Xiufeng Chen
Shumin Wang
Anqi Liu
Hongyu Zhang
Zihao Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1387359

1,922 views

Systematic Review

Published on 03 Jul 2024

Intravenous esketamine as an adjuvant for sedation/analgesia outside the operating room: a systematic review and meta-analysis

in Experimental Pharmacology and Drug Discovery

Ziheng Kan
Weixiang Min
Yuee Dai
Peng Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1287761

1,699 views
1 citation

Original Research

Published on 02 Jul 2024

Virtual screening, molecular docking, MD simulation studies, DFT calculations, ADMET, and drug likeness of Diaza-adamantane as potential MAPKERK inhibitors

in Experimental Pharmacology and Drug Discovery

Davood Gheidari
Morteza Mehrdad
Foroozan Hoseini

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1360226

2,204 views
3 citations

Original Research

Published on 01 Jul 2024

In Vitro evaluation of the anti-pancreatic cancer activity of epimedium herb

in Experimental Pharmacology and Drug Discovery

Yangfeng Chen
Han Xia
Xiaohong Zhong

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1389221

1,506 views

Original Research

Published on 28 Jun 2024

Structure-based screening of FDA-approved drugs identifies potential histone deacetylase 3 repurposed inhibitor: molecular docking and molecular dynamic simulation approaches

in Experimental Pharmacology and Drug Discovery

Anas Shamsi
Mohd Shahnawaz Khan
Dharmendra Kumar Yadav
Moyad Shahwan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1424175

1,697 views
3 citations

Original Research

Published on 26 Jun 2024

Huangqin Qingre Chubi Capsule inhibits rheumatoid arthritis by regulating intestinal flora and improving intestinal barrier

in Experimental Pharmacology and Drug Discovery

Yanhui Peng
Yurong Huang
Hui Li
Chen Li
Yajie Wu
Zhe-Sheng Chen
Xiao Wang
Faxue Liao
Chenggui Miao

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1422245

1,912 views
2 citations

Review

Published on 26 Jun 2024

Research progress on the application of organoids in gynecological tumors

in Experimental Pharmacology and Drug Discovery

Ying Shen
Yu Wang
Si-yu Wang
Chan Li
Feng-Juan Han

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1417576

2,195 views
3 citations

Original Research

Published on 26 Jun 2024

Mirogabalin inhibits scratching behavior of spontaneous model mouse of atopic dermatitis

in Experimental Pharmacology and Drug Discovery

Kosuke Matsuda
Yutaka Kitano
Masahito Sawahata
Toshiaki Kume
Daisuke Uta

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1382281

1,936 views

Review

Published on 25 Jun 2024

The application of organoids in colorectal diseases

in Experimental Pharmacology and Drug Discovery

Yanxin Liu
Dongxu Wang
Yanhong Luan
Boqiang Tao
Qirong Li
Qiang Feng
Hengzong Zhou
Jianfeng Mu
Jinhai Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1412489

2,628 views
1 citation

Brief Research Report

Published on 25 Jun 2024

BRCA1 foci test as a predictive biomarker of olaparib response in ovarian cancer patient-derived xenograft models

in Experimental Pharmacology and Drug Discovery

Federica Guffanti
Ilaria Mengoli
Maria Francesca Alvisi
Giulia Dellavedova
Raffaella Giavazzi
Robert Fruscio
Eliana Rulli
Giovanna Damia

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1390116

1,299 views

Perspective

Published on 21 Jun 2024

Possible opportunities and challenges for traditional Chinese medicine research in 2035

in Experimental Pharmacology and Drug Discovery

Nanqu Huang
Wendi Huang
Jingjing Wu
Sheng Long
Yong Luo
Juan Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1426300

4,266 views
7 citations

Systematic Review

Published on 20 Jun 2024

Repurposing effect of cardiovascular-metabolic drug to increase lifespan: a systematic review of animal studies and current clinical trial progress

in Experimental Pharmacology and Drug Discovery

Agian Jeffilano Barinda
Harri Hardi
Melva Louisa
Nurul Gusti Khatimah
Rheza Meida Marliau
Immanuel Felix
Muhamad Rizqy Fadhillah
Arief Kurniawan Jamal

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1373458

2,788 views
1 citation

Original Research

Published on 20 Jun 2024

Integrated analysis of genes shared between type 2 diabetes mellitus and osteoporosis

in Experimental Pharmacology and Drug Discovery

Fangyu Li
Ying Wang
Jie Cao
Qi Chen
Yuanyuan Gao
Rui Li
Li Yuan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1388205

2,814 views
2 citations

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Articles

PTGES2 and RNASET2 identified as novel potential biomarkers and therapeutic targets for basal cell carcinoma: insights from proteome-wide mendelian randomization, colocalization, and MR-PheWAS analyses

Corrigendum: Anti-inflammatory and antioxidant effects of flavonoid-rich fraction of bergamot juice (BJe) in a mouse model of intestinal ischemia/reperfusion injury

The potential application of fermented tea as a drink for regulating bone mass

Long Mu Qing Xin mixture improves behavioral performance in spontaneously hypertensive rats (SHR/NCrl) by upregulating catecholamine neurotransmitters in prefrontal cortex and striatum via DRD1/cAMP/PKA-CREB signaling pathway

Intravenous esketamine as an adjuvant for sedation/analgesia outside the operating room: a systematic review and meta-analysis

Virtual screening, molecular docking, MD simulation studies, DFT calculations, ADMET, and drug likeness of Diaza-adamantane as potential MAPKERK inhibitors

In Vitro evaluation of the anti-pancreatic cancer activity of epimedium herb

Structure-based screening of FDA-approved drugs identifies potential histone deacetylase 3 repurposed inhibitor: molecular docking and molecular dynamic simulation approaches

Huangqin Qingre Chubi Capsule inhibits rheumatoid arthritis by regulating intestinal flora and improving intestinal barrier

Research progress on the application of organoids in gynecological tumors

Mirogabalin inhibits scratching behavior of spontaneous model mouse of atopic dermatitis

The application of organoids in colorectal diseases

BRCA1 foci test as a predictive biomarker of olaparib response in ovarian cancer patient-derived xenograft models

Possible opportunities and challenges for traditional Chinese medicine research in 2035

Repurposing effect of cardiovascular-metabolic drug to increase lifespan: a systematic review of animal studies and current clinical trial progress

Integrated analysis of genes shared between type 2 diabetes mellitus and osteoporosis