Frontiers in Pharmacology | Experimental Pharmacology and Drug Discovery

Systematic Review

Published on 02 Jun 2025

Mesenchymal stem cell-derived exosomes for the treatment of knee osteoarthritis: a systematic review and meta-analysis based on rat model

in Experimental Pharmacology and Drug Discovery

Zhe Wang
Zihao Hu
Lin Niu
Yongsheng Xu
Yansong Qi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1588841

1,421 views

Original Research

Published on 02 Jun 2025

Identification of compounds to promote diabetic wound healing based on transcriptome signature

in Experimental Pharmacology and Drug Discovery

Jiamin Shang
Zhaoyu Liu
Meidai Liang
Zijie Yin
Zeyu Yang
Xiaomeng Ye
Guanhua Du
Xiuying Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1576056

823 views

Original Research

Published on 02 Jun 2025

Blood metabolites as mediators in erectile dysfunction: insights from a multi-center proteomics and genetic study

in Experimental Pharmacology and Drug Discovery

Junhao Chen
Junxian Zhao
Zhi Zhang
Xingcheng Zhu
Jieming Zuo
Zuqing Nie
Yuanzhi Fu
Haifeng Wang
Mengjun Tang
Shi Fu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1568780

1,117 views

Original Research

Published on 02 Jun 2025

The protective role of vitamin C against linezolid-induced hepato-renal toxicity in a rat model

in Experimental Pharmacology and Drug Discovery

Shaimaa M. Azzam
Hend Mohamed Anwar
Ahmed H. Abd El-Slam
Marwa S. M. Diab
Halima Mohamed Ibrahim
Abdalrahman Mohammed Yousef
Fatma Mahmoud Sabry
Ibrahim A. Darwish
Kalidasan Kaliyamoorthy
Gad Elsayed Mohamed Salem

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1551062

850 views

Original Research

Published on 30 May 2025

Enhanced resistance to Listeria infection in mice surviving sepsis: the role of lipid metabolism and myeloid cell reprogramming

in Experimental Pharmacology and Drug Discovery

Haruki Watanabe
Tengfei Song
Jaewoo Choi
Moses Lee
Kwangmin Choi
Junhwan Kim
Barbara Sherry
Betty Diamond
Yong-Rui Zou
Myoungsun Son

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1588987

917 views

Original Research

Published on 30 May 2025

Protective effects of shikimic acid against thioacetamide-induced hepatic fibrosis: role of Nrf2/NF-κB signaling pathways

in Experimental Pharmacology and Drug Discovery

Ashraf Albrakati

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1609711

672 views

Original Research

Published on 30 May 2025

Network-based analysis and experimental validation of identified natural compounds from Yinchen Wuling San for acute myeloid leukemia

in Experimental Pharmacology and Drug Discovery

Biyu Zhang
Denggang Fu
Xin Wang
Xuelei Hu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1591164

1,120 views

Original Research

Published on 30 May 2025

Ursolic acid drug-drug nanocrystals ameliorate cholestatic liver injury via inhibiting oxidative stress and regulating bile acid metabolism

in Experimental Pharmacology and Drug Discovery

Manhang Hu
Xiaolu Hua
Wei Xiong
Enhui Zheng
Xingyue Yang
Yu Lu
Bing He
Xiaolin Zhong
Zongzhe Jiang
Qingbi Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1586141

760 views

Original Research

Published on 30 May 2025

Perfusion pressure as a determinant of respiratory function outcomes in unilateral biportal lumbar endoscopic procedures

in Experimental Pharmacology and Drug Discovery

Liang Zhang
Han Zheng
Yan Fu
Wenbo Li
Jianlong Lang
Yi Wang
Weibin Ren

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1593118

610 views

Original Research

Published on 30 May 2025

7-α-O-Methylmorroniside ameliorated brain injury in 5×FAD mice by regulating the gut microbiome and NMDAR2B

in Experimental Pharmacology and Drug Discovery

Fengxiao Hao
Mengnan Zeng
Bing Cao
Xiwen Liang
Zhiyou Hao
Kaili Ye
Xinmian Jiao
Weisheng Feng
Xiaoke Zheng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1545566

533 views

Original Research

Published on 30 May 2025

Multimodal endovascular management of traumatic carotid-cavernous fistulas: case series and lessons learned

in Experimental Pharmacology and Drug Discovery

Shangdi Yang
Richao Chen
Mingjia Yi
Chuangnan Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1602971

406 views

Original Research

Published on 30 May 2025

Vitexicarpin suppresses colorectal and non-small cell lung cancer via selective inhibition of Anoctamin 1

in Experimental Pharmacology and Drug Discovery

Yohan Seo
Sion Lee
Raju Das
Sung Baek Jeong
Chul Soon Park
Minuk Kim
Deok Kyu Yoon
Armin Sultana
Kantu Das
Jae-Eon Lee

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1557193

773 views

Original Research

Published on 29 May 2025

Deep learning-based action recognition for analyzing drug-induced bone remodeling mechanisms

in Experimental Pharmacology and Drug Discovery

Li Qinsheng
Li Ming
Li Yuening
Zhao Xiufeng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1564157

581 views

Original Research

Published on 23 May 2025

Identification of biomarkers and potential drug targets in DFU based on fundamental experiments and multi-omics joint analysis

in Experimental Pharmacology and Drug Discovery

Xudong Xin
Haidong Zhou
Song Huang
Wenzhao Zhang
Jiahou Xu
Wei Wang
Jihua Wei
Liqing Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1561179

1,720 views

Review

Published on 23 May 2025

Research progress in the treatment of non-scarring alopecia: mechanism and treatment

in Experimental Pharmacology and Drug Discovery

Rui-Xian Guo
Yong-Kang Zhao
Ke-Jian Hu
Kun-Mu Jia
Wei Shi
Yan-Xiao Yi
Hai-Ying Gong
Jia-Bo Wang
Yuan Gao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1544068

1,609 views

Original Research

Published on 23 May 2025

No significant gender differences in driving-related skills following alcohol mixed with energy drinks during an experimental binge-drinking episode

in Experimental Pharmacology and Drug Discovery

Olga Hladun
Esther Papaseit
Lourdes Poyatos
Soraya Martín
Ana Pilar Pérez-Acevedo
Ana Maria Barriocanal
Tatiana Bustos-Cardona
Susana Malumbres
Rafael De La Torre
Klaus Langohr

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1581229

1,057 views