Frontiers in Pharmacology | Inflammation Pharmacology

Review

Published on 12 Nov 2025

Epigenetic programming reshapes innate immune memory: decoding the molecular imprint of gouty inflammation

in Inflammation Pharmacology

Wenjie Su
Yifan Lu
Zhiqiang Luo
Hui Xiong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1678958

529 views

Systematic Review

Accepted on 11 Nov 2025

Effectiveness and Safety of Tocilizumab in Refractory Non-Infectious Uveitis: A Systematic Review and Meta-analysis

in Inflammation Pharmacology

Huanmin Kang
Xue Wu
Hanyue Xu
Yufan Huang
Ming Zhang

Frontiers in Pharmacology

Review

Published on 10 Nov 2025

Decoding the heterogeneity of liver-resident macrophages in chronic liver diseases: therapeutic responses to immunomodulatory strategies

in Inflammation Pharmacology

Renbin Ouyang
Xiaocheng Li
Jianhua Hao
Jie Lin
Hui Lan
Jing Peng
Xinmin Li
Zhiliang Tian
Yu Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1708240

372 views

Review

Published on 10 Nov 2025

Recent advances in understanding oxidative stress in sepsis: pathogenic roles and antioxidant therapeutic prospects - a narrative review

in Inflammation Pharmacology

Yijuan Lin
Ahmad Alhaskawi
Lin Chen
Safwat Adel Abdo Moqbel

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1695992

404 views

Original Research

Published on 10 Nov 2025

Modulation of TNFα-driven neuroinflammation by Gardenin A: insights from in vitro, in vivo, and in silico studies

in Inflammation Pharmacology

Prashsti Chadha
Hiral Aghara
Harshrajsinh Solanki
Manali Patel
Dhrubjyoti Sharma
Vijay Thiruvenkatam
Palash Mandal

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1681403

911 views

Review

Published on 07 Nov 2025

AMPK signaling in osteoarthritis: from mechanisms to targeted therapeutics

in Inflammation Pharmacology

Lin Chen
Xiu-Hua Hu
Xin-Yi Wu
Xin Zhang
Yu-Xin Han
Yi Liu
Guang-Yao Chen
Qing-Wen Tao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1681610

390 views

Systematic Review

Published on 06 Nov 2025

Clinical benefits and complication profile of IL-23 inhibitors in patients with psoriatic arthritis: a systematic review and meta-analysis

in Inflammation Pharmacology

Jingxin Zeng
Ling Lin
Wei Li
Xinjing Gao
Qian Li
Xin Zhou
Weiyu Liu
Xuelian Zhong
Yunqing Yang
Xibao Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1669786

427 views

Original Research

Accepted on 05 Nov 2025

Omega 3 fatty acid Docosahexaenoic Acid (DHA) mitigates inflammatory responses in experimental sepsis

in Inflammation Pharmacology

Bianca Portugal Tavares de Moraes
Isabelle de Moraes Souza
Gabrielle Lacerda de Souza Gomes
Marina Ferreira Costa
Carolina Medina Coeli da Cunha
Matheus Augusto Patrício de Almeida
Vanessa Estato
Kaue Souza
Francisco da Silva dos Santos
Maria Alice Santos-Mascarenhas

Frontiers in Pharmacology

218 views

Original Research

Accepted on 03 Nov 2025

Ivarmacitinib improves patient-reported outcomes across multiple domains in patients with active ankylosing spondylitis: a post hoc analysis of a phase II/III trial

in Inflammation Pharmacology

Xiaoyan Xu
Hua Wei
Linchen Liu
Rong Yang
Qing Shi
Dandan Pang

Frontiers in Pharmacology

101 views

Original Research

Accepted on 30 Oct 2025

Ivarmacitinib reduces the need for adding/escalating medications in moderate-to-severe rheumatoid arthritis patients: a post-hoc analysis from a phase III trial

in Inflammation Pharmacology

Huaxiang Liu
Jie Li
Lijun Song

Frontiers in Pharmacology

Original Research

Published on 30 Oct 2025

1-stearoyl-2-arachidonoyl-driven B Cell metabolic dysregulation in chronic rhinosinusitis with nasal polyps: insights from Mendelian randomization and single-cell RNA sequencing

in Inflammation Pharmacology

Jian Wu
Yifang Sun
Shuyue Wang
Qian Zhang
Ying Lin
Caipeng Liu
Maomao Ai
Feng Yu
Lei Cao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1719897

508 views

Original Research

Published on 28 Oct 2025

Regulation of inflammatory pathways by cannabigerol in the collagen induced arthritis model in rats

in Inflammation Pharmacology

Monika Šteigerová
Michaela Sklenárová
Mykhaylo Bazyuk
Luděk Záveský
Petr Jelínek
Mahak Arora
Daniel Stránský
Tomáš Kučera
Bruno Sepodes
Miroslav Šoóš

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1705962

677 views

Original Research

Accepted on 27 Oct 2025

A real-world pharmacovigilance study of FDA Adverse Event Reporting System (FAERS) events for bimekizumab

in Inflammation Pharmacology

Zhuomiao Lin
Xihui Yu
Mei Qing Yang
Jialan Xu
Jiahong Zhong

Frontiers in Pharmacology

269 views

Original Research

Accepted on 27 Oct 2025

Carnosine as a Protective Metabolic Mediator in Inflammatory Lung Injury by Inhibiting Macrophage Infiltration and M1-like Polarization

in Inflammation Pharmacology

Lianjie Ruan
Binqin Lin
Qingqing Zhan
Dekai Lin
Lili Zheng
Dandan Lin
Yaoning Zhuang
Yiming Zeng

Frontiers in Pharmacology

157 views

Systematic Review

Published on 27 Oct 2025

Comparison of multiple doses of corticosteroids in Kawasaki disease: a Bayesian network analysis

in Inflammation Pharmacology

Xuan Li
Xuan Tang
Daoping Yang
Miao Hou
Qiuqin Xu
Yunjia Tang
Bo Wang
Hongbiao Huang
Ye Chen
Zhiheng Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1661380

1,308 views

Original Research

Published on 22 Oct 2025

CU06-1004 inhibits the progression of chronic colitis and colitis-associated colorectal cancer by suppressing inflammation

in Inflammation Pharmacology

Dongyeop Kim
Yeomyeong Kim
Haiying Zhang
Ye-Seul Kim
Minyoung Noh
Cho-Rong Bae
Young-Guen Kwon
Sang-Jun Ha

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1684870

1,067 views