Frontiers in Pharmacology | Inflammation Pharmacology

Original Research

Published on 29 Feb 2024

Modification of 4-(4-chlorothiophen-2-yl)thiazol-2-amine derivatives for the treatment of analgesia and inflammation: synthesis and in vitro, in vivo, and in silico studies

in Inflammation Pharmacology

Mater H. Mahnashi
Umer Rashid
Hassan Hussain Almasoudi
Mohammed H. Nahari
Imran Ahmad
Abdulkarim S. Binshaya
Osama Abdulaziz
Meshari A. Alsuwat
Muhammad Saeed Jan
Abdul Sadiq

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1366695

7,966 views
9 citations

Review

Published on 23 Feb 2024

Lipotoxicity and immunometabolism in ischemic acute kidney injury: current perspectives and future directions

in Inflammation Pharmacology

Afolarin A. Otunla
Kumaran Shanmugarajah
Alun H. Davies
Joseph Shalhoub

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1355674

4,736 views
10 citations

Original Research

Published on 21 Feb 2024

Capsaicin ameliorate pulmonary fibrosis via antioxidant Nrf-2/ PPAR- γ pathway activation and inflammatory TGF-β1/ NF-κB/COX II pathway inhibition

in Inflammation Pharmacology

Wesam H. Abdulaal
Hani Z. Asfour
Nawal Helmi
Hadeel Al Sadoun
Basmah Eldakhakhny
Nabil A. Alhakamy
Hani Mohammed Alqarni
Saeed Ali Mohammed Alzahrani
Mohamed A. El-Moselhy
Sara S. Sharkawi

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1333715

5,978 views
12 citations

Review

Published on 15 Feb 2024

Regulation of inflammation during wound healing: the function of mesenchymal stem cells and strategies for therapeutic enhancement

in Inflammation Pharmacology

Mingnan Gao
Han Guo
Xuan Dong
Zimao Wang
Zheng Yang
Qiaoli Shang
Qiying Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1345779

15,418 views
63 citations

Original Research

Published on 15 Feb 2024

Hyaluronic acid-ibuprofen conjugation: a novel ototherapeutic approach protecting inner ear cells from inflammation-mediated damage

in Inflammation Pharmacology

Bhaskar Birru
Joachim G. S. Veit
Elizabeth M. Arrigali
Jack Van Tine
Emma Barrett-Catton
Zachary Tonnerre
Philippe Diaz
Monica A. Serban

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1355283

3,568 views
4 citations

Original Research

Published on 13 Feb 2024

Melittin promotes dexamethasone in the treatment of adjuvant rheumatoid arthritis in rats

in Inflammation Pharmacology

Linfu Yang
Xiying He
Dandan Zhi
Yunfei Xue
Xueyang Gong
Kun Dong
Yakai Tian

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1338432

4,246 views
10 citations

Systematic Review

Published on 07 Feb 2024

Efficacy of hyaluronic acid in the treatment of nasal inflammatory diseases: a systematic review and meta-analysis

in Inflammation Pharmacology

Huixia Liu
Yue Chen
Huan Wang
Xinyi Luo
Dengpiao Xie
Qing Ji
Li Tian

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1350063

9,015 views
7 citations

Perspective

Published on 07 Feb 2024

Pharmacological targeting of the hyper-inflammatory response to SARS-CoV-2-infected K18-hACE2 mice using a cluster of differentiation 36 receptor modulator

in Inflammation Pharmacology

Jade Gauvin
David N. Huynh
Isabelle Dubuc
Catherine Lê
Rafaela Tugores
Nicolas Flamand
Louis Flamand
William D. Lubell
Huy Ong
Sylvie Marleau

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1303342

2,225 views
2 citations

Review

Published on 02 Feb 2024

Therapeutic potential of hydrogen sulfide in osteoarthritis development

in Inflammation Pharmacology

Yunjia Song
Siyu Wu
Rong Zhang
Qing Zhong
Xuanming Zhang
Xutao Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1336693

6,929 views
15 citations

Original Research

Published on 23 Jan 2024

Mechanistic evaluation of antiarthritic and anti-inflammatory effect of campesterol ester derivatives in complete Freund’s adjuvant-induced arthritic rats

in Inflammation Pharmacology

Sarwat Nazir
Ishtiaq Ahmad
Aisha Mobashar
Ali Sharif
Arham Shabbir
Waqas Ashraf Chaudhary

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1346054

6,891 views
20 citations

Systematic Review

Published on 19 Jan 2024

Denosumab, teriparatide and bisphosphonates for glucocorticoid-induced osteoporosis: a Bayesian network meta-analysis

in Inflammation Pharmacology

Liang Dong
Lianghai Jiang
Zhengwei Xu
Xiaobo Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1336075

8,073 views
8 citations

Original Research

Published on 15 Jan 2024

Valsartan attenuates LPS-induced ALI by modulating NF-κB and MAPK pathways

in Inflammation Pharmacology

Mi Zhou
Ling Meng
Qinke He
Chunguang Ren
Changyi Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1321095

11,151 views
23 citations

Correction

Published on 11 Jan 2024

Corrigendum: Sorafenib increases cytochrome P450 lipid metabolites in patient with hepatocellular carcinoma

in Inflammation Pharmacology

Can G. Leineweber
Miriam Rabehl
Anne Pietzner
Nadine Rohwer
Michael Rothe
Maciej Pech
Bruno Sangro
Rohini Sharma
Chris Verslype
Bristi Basu

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1354581

1,684 views

Original Research

Published on 09 Jan 2024

Agranulocytosis and secondary infection related to JAK inhibitors and IL-6 receptor blockers: a disproportionality analysis using the US Food and drug administration adverse event reporting system

in Inflammation Pharmacology

Chunyan Wei
Wanhong Yin
Tingting Hu
Jingyi Zhang
Huifang Dan
Bin Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1323240

3,934 views
3 citations

Review

Published on 08 Jan 2024

Pterostilbene in the treatment of inflammatory and oncological diseases

in Inflammation Pharmacology

Peijun Liu
Weihua Tang
Kali Xiang
Guangcai Li

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1323377

24,741 views
37 citations

Mini Review

Published on 03 Jan 2024

Potential applications of JAK inhibitors, clinically approved drugs against autoimmune diseases, in cancer therapy

in Inflammation Pharmacology

Xiao-Huan Wei
Yuan-Yuan Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1326281

10,230 views
17 citations

Editorial

Published on 14 Dec 2023

Editorial: Implication of oxidative, inflammatory, apoptotic and autophagy pathways in colitis

in Inflammation Pharmacology

Hanan M. Hassan
Mohamed M. Salama

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1326176

1,863 views

Systematic Review

Published on 07 Dec 2023

Efficacy and safety of iguratimod in the treatment of rheumatic and autoimmune diseases: a meta-analysis and systematic review of 84 randomized controlled trials

in Inflammation Pharmacology

Liuting Zeng
Qi He
Ying Deng
Yuwei Li
Junpeng Chen
Kailin Yang
Yanfang Luo
Anqi Ge
Xiaofei Zhu
Zhiyong Long

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1189142

7,609 views
8 citations

Original Research

Published on 07 Dec 2023

A real-world disproportionality analysis of mepolizumab based on the FDA adverse event reporting system

in Inflammation Pharmacology

Huqun Li
Chongshu Wang
Aiping Deng
Cuilian Guo

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1280490

4,296 views
9 citations

Editorial

Published on 06 Dec 2023

Editorial: Lipidomics of oxylipins in biological systems

in Inflammation Pharmacology

Paola Patrignani
Nils Helge Schebb
Oliver Werz
Dieter Steinhilber

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1342596

2,793 views

Original Research

Published on 29 Nov 2023

ACT001 improved cardiovascular function in septic mice by inhibiting the production of proinflammatory cytokines and the expression of JAK-STAT signaling pathway

in Inflammation Pharmacology

Zhen Peng
Xiaolong Lv
Xintong Wang
Ting Shang
Jing Chang
Khalid Salahdiin
Yue Guo
Zhisen Zhang
Ru Shen
Ming Lyu

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1265177

5,879 views
7 citations

Original Research

Published on 20 Nov 2023

IL-37 counteracts inflammatory injury in the temporomandibular joint via the intracellular pathway

in Inflammation Pharmacology

Jun Li
Sisi Peng
Ying Yan
Shan Yan
Xin Cao
Yong Li
Luying Zhu
Jie Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1250216

3,157 views

Review

Published on 16 Nov 2023

Current and promising therapies based on the pathogenesis of Graves’ ophthalmopathy

in Inflammation Pharmacology

Xin Zhang
Qixiang Zhao
Bei Li

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1217253

8,878 views
15 citations

Review

Published on 15 Nov 2023

Immunomodulatory roles of metalloproteinases in rheumatoid arthritis

in Inflammation Pharmacology

Yanqin Bian
Zheng Xiang
Yaofeng Wang
Qing Ren
Guoming Chen
Bei Xiang
Jianye Wang
Chengbo Zhang
Shaoqiang Pei
Shicheng Guo

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1285455

11,681 views
48 citations

1,846 articles

articles

Modification of 4-(4-chlorothiophen-2-yl)thiazol-2-amine derivatives for the treatment of analgesia and inflammation: synthesis and in vitro, in vivo, and in silico studies

Lipotoxicity and immunometabolism in ischemic acute kidney injury: current perspectives and future directions

Capsaicin ameliorate pulmonary fibrosis via antioxidant Nrf-2/ PPAR- γ pathway activation and inflammatory TGF-β1/ NF-κB/COX II pathway inhibition

Regulation of inflammation during wound healing: the function of mesenchymal stem cells and strategies for therapeutic enhancement

Hyaluronic acid-ibuprofen conjugation: a novel ototherapeutic approach protecting inner ear cells from inflammation-mediated damage

Melittin promotes dexamethasone in the treatment of adjuvant rheumatoid arthritis in rats

Efficacy of hyaluronic acid in the treatment of nasal inflammatory diseases: a systematic review and meta-analysis

Pharmacological targeting of the hyper-inflammatory response to SARS-CoV-2-infected K18-hACE2 mice using a cluster of differentiation 36 receptor modulator

Therapeutic potential of hydrogen sulfide in osteoarthritis development

Mechanistic evaluation of antiarthritic and anti-inflammatory effect of campesterol ester derivatives in complete Freund’s adjuvant-induced arthritic rats

Denosumab, teriparatide and bisphosphonates for glucocorticoid-induced osteoporosis: a Bayesian network meta-analysis

Valsartan attenuates LPS-induced ALI by modulating NF-κB and MAPK pathways

Corrigendum: Sorafenib increases cytochrome P450 lipid metabolites in patient with hepatocellular carcinoma

Agranulocytosis and secondary infection related to JAK inhibitors and IL-6 receptor blockers: a disproportionality analysis using the US Food and drug administration adverse event reporting system

Pterostilbene in the treatment of inflammatory and oncological diseases

Potential applications of JAK inhibitors, clinically approved drugs against autoimmune diseases, in cancer therapy

Editorial: Implication of oxidative, inflammatory, apoptotic and autophagy pathways in colitis

Efficacy and safety of iguratimod in the treatment of rheumatic and autoimmune diseases: a meta-analysis and systematic review of 84 randomized controlled trials

A real-world disproportionality analysis of mepolizumab based on the FDA adverse event reporting system

Editorial: Lipidomics of oxylipins in biological systems

ACT001 improved cardiovascular function in septic mice by inhibiting the production of proinflammatory cytokines and the expression of JAK-STAT signaling pathway

IL-37 counteracts inflammatory injury in the temporomandibular joint via the intracellular pathway

Current and promising therapies based on the pathogenesis of Graves’ ophthalmopathy

Immunomodulatory roles of metalloproteinases in rheumatoid arthritis