Frontiers in Pharmacology | Inflammation Pharmacology

Original Research

Published on 25 Mar 2025

Phenylethyl isothiocyanate mitigates drug-induced liver injury in mice by inhibiting hepatocyte pyroptosis through the NLRP3-caspase-1-GSDMD pathway

in Inflammation Pharmacology

Ning An
Xiaoru Wang
Jia Qin
Meng Cheng
Mei Bai
Jingcai Cheng
Qiang Xu
Xuefeng Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1539934

217 views

Review

Accepted on 24 Mar 2025

Research progress on the mechanism of curcumin anti-oxidative stress based on signaling pathway

in Inflammation Pharmacology

Jie Cui
Haonan Li
Tianyi Zhang
Fengli Lin
Meiyuun Chen
Guimin Zhang
Zhong Feng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1548073

Review

Accepted on 24 Mar 2025

Natural Saponins and Macrophage Polarization: Mechanistic Insights and Therapeutic Perspectives in Disease Management

in Inflammation Pharmacology

Beibei Xiong
Huan Wang
Yi-Xuan Song
Wen-Ying Lan
Jiangtao Li
Fang Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1584035

Review

Accepted on 24 Mar 2025

Oxidative stress in vascular surgical diseases: mechanisms, impacts and therapeutic perspectives

in Inflammation Pharmacology

Haosen Xu
Jin Yang
Zhanhui Wei
Shijie Bao
Zhuo Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1527684

Review

Published on 21 Mar 2025

Cell death in acute lung injury: caspase-regulated apoptosis, pyroptosis, necroptosis, and PANoptosis

in Inflammation Pharmacology

Jun Xiao
Lichuan Wang
Bohan Zhang
Ana Hou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1559659

240 views

Original Research

Published on 20 Mar 2025

Inflammation and platelet hyperresponsiveness in coronary artery disease and the influence of Talin-1/αIIbβ3-mediated bidirectional signaling pathway

in Inflammation Pharmacology

Shengnan Shi
Jiaming Gao
Yehao Zhang
Min Zhan
Zhanfei Tan
Peili Wang
Jianhua Fu
Jianxun Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1535182

203 views

Review

Accepted on 19 Mar 2025

Paeoniflorin: A Review of Its Pharmacology, Pharmacokinetics and Toxicity in Diabetes

in Inflammation Pharmacology

Xue Ou
Zhijie Yu
Chuanyu Pan
Xi Zheng
Dandan Li
Zhenzhen Qiao
Xiaoyuan Zheng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1551368

Mini Review

Published on 19 Mar 2025

Interplay between endogenous hormones and immune systems in human metapneumovirus pathogenesis and management

in Inflammation Pharmacology

Viviana A. Ruiz-Pozo
Santiago Cadena-Ullauri
Rafael Tamayo-Trujillo
Patricia Guevara-Ramírez
Elius Paz-Cruz
Mayra A. Castañeda Cataña
Ana Karina Zambrano

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1568828

266 views

Original Research

Published on 19 Mar 2025

Effect of anti-interleukin-5 antibody on development of vasculitis in an ovalbumin-induced eosinophilic vasculitis mouse model

in Inflammation Pharmacology

Kiyoto Kageyama
Eri Kikuchi
Nao Hoshino

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1546785

202 views

Review

Published on 18 Mar 2025

Ferroptosis and hyperoxic lung injury: insights into pathophysiology and treatment approaches

in Inflammation Pharmacology

Xiaoqiong Zhou
Lei Tian
Wenyan Xiong
Yulan Li
Qian Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1568246

279 views

Original Research

Published on 18 Mar 2025

The role and impact of the IL-6 mediated JAK2-STAT1/3 signaling pathway in the pathogenesis of gout

in Inflammation Pharmacology

Zeng Zhang
Peng Wang
Tianyi Lei
Jianwei Guo
Yi Jiang
Yanhui Li
Jianxiong Zheng
Shunbing Wang
Haimuzi Xu
Guilin Jian

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1480844

479 views

Review

Accepted on 13 Mar 2025

Anti-inflammatory Drugs as Potential Antimicrobial Agents: A Review

in Inflammation Pharmacology

Onyedika Emmanuel Okpala
Johana Rondevaldova
Ladislav Kokoska

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1557333

150 views

Original Research

Published on 13 Mar 2025

Mechanism of nimodipine in treating neurodegenerative diseases: in silico target identification and molecular dynamic simulation

in Inflammation Pharmacology

Shuang Zheng
Yin Wang
Shuainan Tang
Yuntao Guo
Duan Ma
Xin Jiang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1549953

396 views

Original Research

Published on 12 Mar 2025

Deciphering the role of IGFBP5 in delaying fibrosis and sarcopenia in aging skeletal muscle: therapeutic implications and molecular mechanisms

in Inflammation Pharmacology

Luze Shi
Zheci Ding
Jiwu Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1557703

506 views

Mini Review

Published on 12 Mar 2025

Salt-sensitive hypertension: role of endothelial and vascular dysfunction and sex

in Inflammation Pharmacology

Helen M. Butler
Marice K. McCrorey
Lada Palygina
Ryan Lacey
Justin P. Van Beusecum

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1565962

477 views

Brief Research Report

Published on 07 Mar 2025

Efficacy and safety of conventional disease-modifying antirheumatic drugs in VEXAS syndrome: real-world data from the international AIDA network

in Inflammation Pharmacology

Antonio Vitale
Flavia Leone
Valeria Caggiano
Andrea Hinojosa-Azaola
Eduardo Martín-Nares
Guillermo Arturo Guaracha-Basañez
Jiram Torres-Ruiz
Perla Ayumi Kawakami-Campos
Pravin Hissaria
Alicia Callisto

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1539756

795 views