Frontiers in Pharmacology | Inflammation Pharmacology

Systematic Review

Published on 05 Jan 2026

Comparative efficacy and safety of imrecoxib versus celecoxib: a systematic review and meta-analysis

in Inflammation Pharmacology

Xian Zeng
Lilin Dai
Zude Li
Xiaomin Dong
Zengzhen Liao
Liji Chen
Yuan Tan
Wei Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1707079

905 views

Review

Published on 05 Jan 2026

Molecular insights into NLRP3 inflammasome and miRNA modulation in oral cancer

in Inflammation Pharmacology

Deborah Mannino
Morena D’Ariano
Ivana Bello
Irene Paterniti
Giovanna Casili
Elisabetta Panza

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1713259

1,069 views

Original Research

Published on 05 Jan 2026

A real-world pharmacovigilance study of FDA adverse event reporting system (FAERS) events for bimekizumab

in Inflammation Pharmacology

Zhuomiao Lin
Xihui Yu
Meiqing Yang
Jialan Xu
Jiahong Zhong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1714173

1,415 views

General Commentary

Published on 05 Jan 2026

Commentary: CU06-1004 inhibits the progression of chronic colitis and colitis-associated colorectal cancer by suppressing inflammation

in Inflammation Pharmacology

Wentao Guo
Yun Wang
Danqin Fang
Zhihui Zeng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1750070

515 views

Original Research

Published on 02 Jan 2026

Neoantigen immune responses in healthy volunteers: insights from multiple integrated keyhole limpet hemocyanin challenge studies on repeated immunization and response covariates

in Inflammation Pharmacology

Micha N. Ronner
Marieke L. De Kam
Silke Van Reeuwijk
Jacobus Burggraaf
Manon A. A. Jansen
Matthijs Moerland

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1717333

985 views

Review

Accepted on 24 Dec 2025

MOLECULAR AND PATHOPHYSIOLOGICAL INTERSECTIONS BETWEEN ARTERIAL HYPERTENSION, PULMONARY INFLAMMATION AND DIABETES MELLITUS

in Inflammation Pharmacology

Higo José Neri da Silva
Antônio Carlos Melo Lima Filho
Ester Miranda Pereira
Ian Jhemes Oliveira Sousa
Francisco Valmor Macedo Cunha
Massimo Lucarini
Alessandra Durazzo
Leonardo da Rocha Sousa
Daniel Dias Rufino Arcanjo

Frontiers in Pharmacology

204 views

Original Research

Published on 19 Dec 2025

Oleanolic acid cubic liquid crystal nanoparticle-based thermosensitive gel attenuates knee osteoarthritis symptoms in rats

in Inflammation Pharmacology

Zhiqi Shi
Fan Jia
Xiaoyu Tang
Qing Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1730566

1,534 views

Original Research

Published on 18 Dec 2025

Inflammatory response in CF airway epithelial cells: a comparative study of modulators and wild-type CFTR rescue

in Inflammation Pharmacology

Amal Kouadri
Camille Lyko
Carine El Hajjar
Johanna Cormenier
Kevin Kevin Gemy
Nadia Alfaidy
Mohamed Benharouga

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1657688

937 views

Original Research

Published on 10 Dec 2025

Isoliensinine confers neuroprotection and alleviates LPS-induced neuroinflammation in microglia by regulating the MAPK/NF-κB signaling

in Inflammation Pharmacology

Mengqin Yuan
Jinda Hu
Lichen Gao
Wei Long
Sirui Wang
Xinyue Tan
Jinyue Hu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1675865

1,208 views

Review

Published on 10 Dec 2025

Immune modulation in inflammatory bowel disease: therapeutic promise of baicalein

in Inflammation Pharmacology

Yang Wang
Luyao Zeng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1723606

1,572 views

Systematic Review

Published on 04 Dec 2025

Effectiveness and safety of tocilizumab in refractory noninfectious uveitis: a systematic review and meta-analysis

in Inflammation Pharmacology

Huanmin Kang
Xue Wu
Hanyue Xu
Yufan Huang
Ming Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1694311

1,574 views

Mini Review

Published on 04 Dec 2025

CX3CR1: a potential microglia-specific PET imaging target in Alzheimer’s and Parkinson’s diseases

in Inflammation Pharmacology

Hongzhi Yang
Yanli Wang
Yulong Xu
Changning Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1678159

1,736 views

Original Research

Published on 03 Dec 2025

The clinical value of PLR, NLR, and MLR in predicting mortality risk in hospitalized patients

in Inflammation Pharmacology

Guoxiang Fang
Yunfei Mo
Yangwen Bao
Chunbiao Gao
Qiuya Pan
Tongbo Lu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1736947

1,171 views

Review

Published on 03 Dec 2025

Dapansutrile in multidisciplinary therapeutic applications: mechanisms and clinical perspectives

in Inflammation Pharmacology

Fuwei Bai
Dongyang Wang
Yingying Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1731165

1,979 views

Opinion

Published on 02 Dec 2025

CCR5-targeted γδ CAR-T cells: a rational step toward HIV-resistant allogeneic immunotherapy

in Inflammation Pharmacology

Lina Hu
Haiyan Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1734423

1,105 views

Original Research

Published on 01 Dec 2025

Acetyl-11-keto-beta-boswellic acid ameliorates monosodium iodoacetate-induced osteoarthritis in rats: implications of HMGB1/TLR4/NF-κB and Nrf2/HO-1

in Inflammation Pharmacology

Hagar B. Abo-Zalam
Abdallah M. Gendy
Bassam Mohamed Ali
Ghada M. Ragab
Heba Mohammed Refat M. Selim
Najat O. Hamed
Fatemah A. Alherz
Asmaa Saleh
Einas M. Yousef
Amira A. El-Gazar

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1694803

1,611 views

Original Research

Published on 28 Nov 2025

Omega 3 fatty acid docosahexaenoic acid (DHA) mitigates inflammatory responses in experimental sepsis

in Inflammation Pharmacology

Bianca Portugal Tavares de Moraes
Isabelle Moraes-de-Souza
Gabrielle Lacerda de Souza Gomes-Reis
Marina Ferreira-Costa
Carolina Medina Coeli da Cunha
Matheus Augusto Patrício de Almeida
Vanessa Estato
Kauê Francisco Corrêa Souza e Souza
Francisco da Silva dos Santos
Maria Alice dos Santos Mascarenhas Brito

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1708348

1,876 views

Original Research

Published on 21 Nov 2025

Carnosine as a protective metabolic mediator in inflammatory lung injury by inhibiting macrophage infiltration and M1-like polarization

in Inflammation Pharmacology

Lianjie Ruan
Dekai Lin
Binqin Lin
Qingqing Zhan
Lili Zheng
Dandan Lin
Yaoning Zhuang
Yiming Zeng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1689575

1,188 views

Original Research

Published on 21 Nov 2025

Ivarmacitinib reduces the need for adding/escalating medications in moderate-to-severe rheumatoid arthritis patients: a post hoc analysis from a phase III trial

in Inflammation Pharmacology

Huaxiang Liu
Jie Li
Lijun Song

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1683508

1,156 views

Systematic Review

Published on 20 Nov 2025

Efficacy of pharmacological interventions and therapeutic exercises for rheumatoid arthritis: a systematic review and meta-analysis

in Inflammation Pharmacology

Timothy Adeyemi
Vitalis Ikenna Chukwuike
Motunrayo Adebukunola Oladimeji
Ufuoma Shalom Ahwinahwi
Victor Ayodeji Ayeni
Aisha Adam Abdullahi
Abdulmuminu Isah
Love Bukola Ayamolowo
Oluchukwu Perpetual Okeke
Olunike Abodunrin

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1686128

2,014 views

Original Research

Published on 20 Nov 2025

Ivarmacitinib improves patient-reported outcomes across multiple domains in patients with active ankylosing spondylitis: a post hoc analysis of a phase II/III trial

in Inflammation Pharmacology

Xiaoyan Xu
Hua Wei
Linchen Liu
Rong Yang
Qing Shi
Dandan Pang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1710434

1,350 views

Review

Published on 12 Nov 2025

Epigenetic programming reshapes innate immune memory: decoding the molecular imprint of gouty inflammation

in Inflammation Pharmacology

Wenjie Su
Yifan Lu
Zhiqiang Luo
Hui Xiong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1678958

1,940 views

Review

Published on 10 Nov 2025

Decoding the heterogeneity of liver-resident macrophages in chronic liver diseases: therapeutic responses to immunomodulatory strategies

in Inflammation Pharmacology

Renbin Ouyang
Xiaocheng Li
Jianhua Hao
Jie Lin
Hui Lan
Jing Peng
Xinmin Li
Zhiliang Tian
Yu Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1708240

1,719 views

Review

Published on 10 Nov 2025

Recent advances in understanding oxidative stress in sepsis: pathogenic roles and antioxidant therapeutic prospects - a narrative review

in Inflammation Pharmacology

Yijuan Lin
Ahmad Alhaskawi
Lin Chen
Safwat Adel Abdo Moqbel

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1695992

2,026 views
1 citation

1,846 articles

articles

Comparative efficacy and safety of imrecoxib versus celecoxib: a systematic review and meta-analysis

Molecular insights into NLRP3 inflammasome and miRNA modulation in oral cancer

A real-world pharmacovigilance study of FDA adverse event reporting system (FAERS) events for bimekizumab

Commentary: CU06-1004 inhibits the progression of chronic colitis and colitis-associated colorectal cancer by suppressing inflammation

Neoantigen immune responses in healthy volunteers: insights from multiple integrated keyhole limpet hemocyanin challenge studies on repeated immunization and response covariates

MOLECULAR AND PATHOPHYSIOLOGICAL INTERSECTIONS BETWEEN ARTERIAL HYPERTENSION, PULMONARY INFLAMMATION AND DIABETES MELLITUS

Oleanolic acid cubic liquid crystal nanoparticle-based thermosensitive gel attenuates knee osteoarthritis symptoms in rats

Inflammatory response in CF airway epithelial cells: a comparative study of modulators and wild-type CFTR rescue

Isoliensinine confers neuroprotection and alleviates LPS-induced neuroinflammation in microglia by regulating the MAPK/NF-κB signaling

Immune modulation in inflammatory bowel disease: therapeutic promise of baicalein

Effectiveness and safety of tocilizumab in refractory noninfectious uveitis: a systematic review and meta-analysis

CX3CR1: a potential microglia-specific PET imaging target in Alzheimer’s and Parkinson’s diseases

The clinical value of PLR, NLR, and MLR in predicting mortality risk in hospitalized patients

Dapansutrile in multidisciplinary therapeutic applications: mechanisms and clinical perspectives

CCR5-targeted γδ CAR-T cells: a rational step toward HIV-resistant allogeneic immunotherapy

Acetyl-11-keto-beta-boswellic acid ameliorates monosodium iodoacetate-induced osteoarthritis in rats: implications of HMGB1/TLR4/NF-κB and Nrf2/HO-1

Omega 3 fatty acid docosahexaenoic acid (DHA) mitigates inflammatory responses in experimental sepsis

Carnosine as a protective metabolic mediator in inflammatory lung injury by inhibiting macrophage infiltration and M1-like polarization

Ivarmacitinib reduces the need for adding/escalating medications in moderate-to-severe rheumatoid arthritis patients: a post hoc analysis from a phase III trial

Efficacy of pharmacological interventions and therapeutic exercises for rheumatoid arthritis: a systematic review and meta-analysis

Ivarmacitinib improves patient-reported outcomes across multiple domains in patients with active ankylosing spondylitis: a post hoc analysis of a phase II/III trial

Epigenetic programming reshapes innate immune memory: decoding the molecular imprint of gouty inflammation

Decoding the heterogeneity of liver-resident macrophages in chronic liver diseases: therapeutic responses to immunomodulatory strategies

Recent advances in understanding oxidative stress in sepsis: pathogenic roles and antioxidant therapeutic prospects - a narrative review