Frontiers in Pharmacology | Inflammation Pharmacology

Original Research

Published on 29 Sep 2025

Targeted ferroptosis of myofibroblasts by tubeimoside I attenuates hypertrophic scar formation

in Inflammation Pharmacology

Jianzhang Wang
Chen Wang
Yulei Jia
Fengchao Chen
Youbin Wang
Juan Du

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1654108

1,820 views

Original Research

Published on 26 Sep 2025

Prostaglandin E2 stimulates opposing effects on inner and outer blood-retina barrier function

in Inflammation Pharmacology

Amy K. Stark
Anna R. Gilmartin
Cayla D. Ontko
Taylor E. Smith
Amanda L. Beall
Gary W. McCollum
John S. Penn

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1608376

1,746 views

Review

Published on 26 Sep 2025

The regulatory effects of luteolin, calycosin, and formononetin on the NLRP3/IL-33/ILC2s axis in the treatment of allergic rhinitis: mechanistic analysis and therapeutic potential

in Inflammation Pharmacology

Meng Jia
Xiaochun Lei
Fuwei Jiang
Detang Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1658772

3,786 views

Mini Review

Published on 16 Sep 2025

Promising therapeutics of enterovirus 71 infection: sunshine behind cloud

in Inflammation Pharmacology

Sheng-Yu You
Shun-Hua Chen
Shih-Min Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1652159

2,341 views
1 citation

Original Research

Published on 15 Sep 2025

Association of dexmedetomidine with short-term outcome in patients with cardiogenic shock: a retrospective propensity score-matched cohort study from MIMIC-IV

in Inflammation Pharmacology

Linfeng Xie
Jing Chen
Bryan Richard Sasmita
Yuanzhu Li
Suxin Luo
Bi Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1644635

3,016 views

Review

Published on 12 Sep 2025

Role of N6-Methyladenosine (m6A) epitranscriptomic mark in regulating viral infections and target for antiviral development

in Inflammation Pharmacology

Mahmoud Bayoumi
Vidya Manju
Luis Martinez-Sobrido
Muhammad Munir

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1667283

2,528 views
1 citation

Review

Published on 11 Sep 2025

GLP-1 receptor agonists: exploration of transformation from metabolic regulation to multi-organ therapy

in Inflammation Pharmacology

Bing Gong
Couwen Li
Zhuang’e Shi
FuPing Wang
Ruanxian Dai
Guobing Chen
Heng Su

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1675552

7,029 views
2 citations

Original Research

Published on 10 Sep 2025

Inhibition of soluble epoxide hydrolase in endotoxin induced pig lung injury

in Inflammation Pharmacology

Niklas Larsson
Cindy B. McReynolds
Sung Hee Hwang
Debin Wan
Jun Yang
Richard Lindberg
Stefan Lehtipalo
Jonas Claesson
Amanda Irgum Liljeström
Alicia Lind

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1652349

2,009 views

Correction

Published on 09 Sep 2025

Correction: Research progress in treatment of rheumatoid arthritis with Sinomenine and related formulations based on different administration routes

in Inflammation Pharmacology

Wenya Wang
Zihui Wang
Aixia Ling
Chunyan Zhang
Mei Lv
Lufen Huang
Yanlian Niu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1685111

1,215 views

Original Research

Published on 08 Sep 2025

Empagliflozin targeting STAT3/Akt/Nrf2 axis promoting diabetic wound healing in rat model

in Inflammation Pharmacology

Rania Magadmi
Dalal Alfawaz
Ahmed Bakhshwin
Fatmah Binzomah Alghamdi
Sultan A. Alfawaz
Duaa M. Bakhshwin
Maha H. Jamal
Roba A. Sofi
Ahmed Esmat

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1678552

2,146 views

Original Research

Published on 04 Sep 2025

Mitochondria-target ubiquinone attenuates bleomycin-induced pulmonary fibrosis

in Inflammation Pharmacology

Ying Jiang
Zhenghui Huang
Ting Zhou
Mi Wu
Juan Zhao
Zheyi Xiong
Rui Wang
Limin Chen
Xiufang Weng
Lan Lin

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1661644

2,537 views

Original Research

Published on 02 Sep 2025

In situ sustained release of icariin from injectable thermosensitive PLGA-PEG-PLGA hydrogels combined with core decompression for steroid-induced osteonecrosis of femoral head

in Inflammation Pharmacology

Yingxing Xu
Kaige Xu
Zehua Wang
Xinyu Tang
Yaping Jiang
Tao Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1643316

2,286 views

Original Research

Published on 01 Sep 2025

Exploring the potential of a thermosensitive in situ gel with Periplaneta americana extracts for efficient wound healing

in Inflammation Pharmacology

Shuai Liu
Shuohan Xu
Hang Lu
Xueyu Gong
Huaipeng Li
Xinyu Fan
Hongwei Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1672818

1,546 views

Original Research

Published on 28 Aug 2025

Opposing profiles of Netrin-1 and adiponectin in metabolic inflammation and insulin resistance

in Inflammation Pharmacology

María Guadalupe Ramos-Zavala
Jesús Jonathan García-Galindo
Alberto Beltrán-Ramírez
Luis Ricardo Balleza-Alejandri
Emiliano Peña-Durán
Alfredo Huerta-Huerta
Edy David Rubio-Arellano
Luis Daniel López-Murillo
Sara Pascoe-Gonzalez
Tannia Isabel Campos-Bayardo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1632956

2,396 views

Review

Published on 21 Aug 2025

Apremilast treatment of immune-mediated inflammatory skin diseases: a narrative review

in Inflammation Pharmacology

Xiaoqian Liang
Jiecheng Zheng
Xueyi Huang
Min Tan
Jia Liao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1633426

3,502 views
1 citation

Systematic Review

Published on 21 Aug 2025

Efficacy and safety of topical vs. oral calcium channel blockers for chronic anal fissures: a systematic review and meta-analysis

in Inflammation Pharmacology

Tianshuo Li
Pengfei Ye
Xinli He
Chen Li
Lanlan Xi
Zuowu Xi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1642347

2,011 views

Correction

Published on 21 Aug 2025

Correction: α-Mangostin alleviated inflammation in rats with adjuvant-induced arthritis by disrupting adipocytes-mediated metabolism-immune feedback

in Inflammation Pharmacology

Ying-Hao Hu
Jun Han
Lin Wang
Chao Shi
Yan Li
Opeyemi Joshua Olatunji
Xiu Wang
Jian Zuo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1671368

891 views

Systematic Review

Published on 11 Aug 2025

Safety of oral JAK inhibitors in treating alopecia areata: a systematic review and network meta-analysis

in Inflammation Pharmacology

Ziyu Qi
Yan Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1576553

4,632 views
1 citation

Clinical Trial

Published on 07 Aug 2025

The anti-inflammatory and antioxidant effects of astaxanthin as an adjunctive therapy in community-acquired pneumonia: a randomized controlled trial

in Inflammation Pharmacology

Fatma Makram Youssef
Hayam Ateyya
Amir Eskander Hanna Samy
Eman Mohamed Elmokadem

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1621308

4,727 views
2 citations

Review

Published on 06 Aug 2025

Research progress in treatment of rheumatoid arthritis with Sinomenine and related formulations based on different administration routes

in Inflammation Pharmacology

Wenya Wang
Zihui Wang
Aixia Ling
Chunyan Zhang
Mei Lv
Lufen Huang
Yanlian Niu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1613679

3,764 views
1 citation

Review

Published on 06 Aug 2025

Exploring dupilumab for asthma: from mechanistic insights to clinical outcomes, safety, and cost-effectiveness

in Inflammation Pharmacology

Omar Z. Ameer
Ghaith K. Mansour
Raghad S. Al-Amoudi
Fahmi M. Abu‐Owaimer

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1631321

8,059 views
2 citations

Original Research

Published on 25 Jul 2025

Unique compound with anti-allergic action: inhibition of Lyn kinase activity by KIRA6

in Inflammation Pharmacology

Goshi Matsushima
Yuri Matsui
Hanano Okamoto
Nagisa Umeda
Mai Kakimoto
Megumi Mino
Tadashi Nakagawa
Kaori Ishii
Yoshimi Matsuo
Daiki Matsubara

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1625798

2,111 views
1 citation

Original Research

Published on 23 Jul 2025

Degradation of IRAK4 for the treatment of lipopolysaccharide-induced acute lung injury in mice

in Inflammation Pharmacology

Bijun Ye
Shiyan Chen
Xiaohao Huang
Yinhong Qiu
Ruixiang Luo
Lulu Zheng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1609923

3,265 views

Original Research

Published on 21 Jul 2025

Role of homovanillic acid esters in the regulation of skin inflammatory pathways and their effect on tight junction protein expression

in Inflammation Pharmacology

Maria Fernanda Cervantes Recalde
Elena Zoe Bogensperger
Joachim Hans
Dominik Stuhlmann
Veronika Somoza
Barbara Lieder

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1629941

1,253 views

1,831 articles

articles

Targeted ferroptosis of myofibroblasts by tubeimoside I attenuates hypertrophic scar formation

Prostaglandin E2 stimulates opposing effects on inner and outer blood-retina barrier function

The regulatory effects of luteolin, calycosin, and formononetin on the NLRP3/IL-33/ILC2s axis in the treatment of allergic rhinitis: mechanistic analysis and therapeutic potential

Promising therapeutics of enterovirus 71 infection: sunshine behind cloud

Association of dexmedetomidine with short-term outcome in patients with cardiogenic shock: a retrospective propensity score-matched cohort study from MIMIC-IV

Role of N6-Methyladenosine (m6A) epitranscriptomic mark in regulating viral infections and target for antiviral development

GLP-1 receptor agonists: exploration of transformation from metabolic regulation to multi-organ therapy

Inhibition of soluble epoxide hydrolase in endotoxin induced pig lung injury

Correction: Research progress in treatment of rheumatoid arthritis with Sinomenine and related formulations based on different administration routes

Empagliflozin targeting STAT3/Akt/Nrf2 axis promoting diabetic wound healing in rat model

Mitochondria-target ubiquinone attenuates bleomycin-induced pulmonary fibrosis

In situ sustained release of icariin from injectable thermosensitive PLGA-PEG-PLGA hydrogels combined with core decompression for steroid-induced osteonecrosis of femoral head

Exploring the potential of a thermosensitive in situ gel with Periplaneta americana extracts for efficient wound healing

Opposing profiles of Netrin-1 and adiponectin in metabolic inflammation and insulin resistance

Apremilast treatment of immune-mediated inflammatory skin diseases: a narrative review

Efficacy and safety of topical vs. oral calcium channel blockers for chronic anal fissures: a systematic review and meta-analysis

Correction: α-Mangostin alleviated inflammation in rats with adjuvant-induced arthritis by disrupting adipocytes-mediated metabolism-immune feedback

Safety of oral JAK inhibitors in treating alopecia areata: a systematic review and network meta-analysis

The anti-inflammatory and antioxidant effects of astaxanthin as an adjunctive therapy in community-acquired pneumonia: a randomized controlled trial

Research progress in treatment of rheumatoid arthritis with Sinomenine and related formulations based on different administration routes

Exploring dupilumab for asthma: from mechanistic insights to clinical outcomes, safety, and cost-effectiveness

Unique compound with anti-allergic action: inhibition of Lyn kinase activity by KIRA6

Degradation of IRAK4 for the treatment of lipopolysaccharide-induced acute lung injury in mice

Role of homovanillic acid esters in the regulation of skin inflammatory pathways and their effect on tight junction protein expression