Frontiers in Pharmacology | Inflammation Pharmacology

Original Research

Published on 30 May 2025

Biodegradable sustained-release microneedle patch loaded with clindamycin hydrochloride: a breakthrough in acne management

in Inflammation Pharmacology

Haomei Fan
Ruohan Liao
Yiling Yang
Yan Xing
Chengdong Zhang
Xuwei Luo
Chao Pu
Liling Wu
Xingping Li
Juhua Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1575635

4,243 views
1 citation

Original Research

Published on 30 May 2025

Determination of nine prostaglandins in the arachidonic acid metabolic pathway with UHPLC-QQQ-MS/MS and application to in vitro and in vivo inflammation models

in Inflammation Pharmacology

Yufeng Huang
Mengxian Wang
Ziqi Yang
Xiaotong Wang
Xinxin Wang
Fan He

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1595059

2,470 views

Review

Published on 30 May 2025

Blockade of IL-1 family cytokines in the treatment of rheumatoid arthritis

in Inflammation Pharmacology

Kexin Wang
Haoge Luo
Liping Liu
Hang Gao
Yanyan Song
Dong Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1577628

5,274 views
5 citations

Review

Published on 23 May 2025

Macrophage polarization in disease therapy: insights from astragaloside IV and cycloastragenol

in Inflammation Pharmacology

Bei-Bei Xiong
Yu-Mei Zhuo
Huan Wang
Qiao-Ling Zheng
Feng Tang
Qun Huang
Man Yao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1598022

4,273 views
4 citations

Review

Published on 19 May 2025

The key players of inflammasomes and pyroptosis in sepsis-induced pathogenesis and organ dysfunction

in Inflammation Pharmacology

Lujian Zhu
Minli Hu
Haoming Xu
Hanglu Xu
Binbin Ren
Ruiyan Xu
Maodong Guo
Haijun Chen
Dehe Zhang
Hao Fang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1586364

3,299 views
3 citations

Review

Published on 19 May 2025

Immunopharmacology of gastric cancer–deciphering immune cell subset responses and nanoparticle-mediated targeting

in Inflammation Pharmacology

Yanting Wang
Ning Ding
Lina Qi
Wenwen Chen
Panyisha Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1611234

2,540 views
3 citations

Editorial

Published on 16 May 2025

Editorial: Inflammation and lipid signaling in disease pathogenesis

in Inflammation Pharmacology

Paola Patrignani
Bernhard Brüne
Angelo Sala
Pietro Minuz
Dieter Steinhilber

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1623707

1,730 views

Original Research

Published on 14 May 2025

Associations between ionomic profile and metabolic abnormalities in a murine model of sodium sulfide induced alopecia areata

in Inflammation Pharmacology

Luning Li
Zhen Sun
Wenxue Sun
Yujuan Zhai
Na Ding
Wei Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1507348

2,324 views

Original Research

Published on 14 May 2025

The green tea component (−)-epigallocatechin-3-gallate protects against cytokine-induced epithelial barrier damage in intestinal epithelial cells

in Inflammation Pharmacology

Rita Rosenthal
Anne Waesch
Kopano Valerie Masete
Alain S. Massarani
Jörg-Dieter Schulzke
Nina A. Hering

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1559812

3,829 views
3 citations

Correction

Published on 13 May 2025

Corrigendum: C16 peptide promotes vascular growth and reduces inflammation in a neuromyelitis optica model

in Inflammation Pharmacology

Haohao Chen
Xiaoxiao Fu
Jinzhan Jiang
Shu Han

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1611115

1,317 views

Original Research

Published on 12 May 2025

Esmolol improves sepsis outcomes through cardiovascular and immune modulation

in Inflammation Pharmacology

Da Jing
Li Xiong
Rong Zhang
Hong Fang
Lin Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1498227

1,873 views
2 citations

Original Research

Published on 09 May 2025

Suppressing chondrocyte cuproptosis by syringaresinol-4-O-β-d-glucoside alleviates gouty arthritis

in Inflammation Pharmacology

Shaotian Fu
Han Du
Xiao Ling
Hanyi Wang
Jianan Chen
Hang Zhang
Wugui Chen
Chengzhao Liu
Hailong Ma
Chengshou Lin

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1565422

3,299 views
3 citations

Review

Published on 09 May 2025

Natural saponins and macrophage polarization: Mechanistic insights and therapeutic perspectives in disease management

in Inflammation Pharmacology

Beibei Xiong
Huan Wang
Yi-Xuan Song
Wen-Ying Lan
Jiangtao Li
Fang Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1584035

3,733 views
3 citations

Original Research

Published on 08 May 2025

Rutin ameliorates LPS-induced acute lung injury in mice by inhibiting the cGAS-STING-NLRP3 signaling pathway

in Inflammation Pharmacology

Xin Zhou
Zhibin Wang
Yuting Wang
Guofeng Xu
Min Luo
Mengwei Zhang
Yuying Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1590096

5,028 views
2 citations

Review

Published on 06 May 2025

Curcumin: a potential anti-photoaging agent

in Inflammation Pharmacology

Yuhong Nie
Yiming Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1559032

7,665 views
8 citations

Original Research

Published on 30 Apr 2025

Effect of methotrexate/dexamethasone combination on epithelial-mesenchymal transition and inflammation gene expression of human RPE cells in-vitro

in Inflammation Pharmacology

Fatemeh Sanie-Jahromi
Mahdi Ravankhah
Hossein Shafi Khani
Seyed Ahmad Razavizadegan
M. Hossein Nowroozzadeh

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1569703

1,913 views

Original Research

Published on 29 Apr 2025

Irisin restrains neuroinflammation in mouse experimental autoimmune encephalomyelitis via regulating microglia activation

in Inflammation Pharmacology

Qiu-Xia Zhang
Lin-Jie Zhang
Ning Zhao
Li Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1561939

2,046 views
2 citations

Original Research

Published on 28 Apr 2025

Anti-inflammatory effect and mechanism of stytontriterpene D on RAW264.7 cells and zebrafish

in Inflammation Pharmacology

Chuqin Yu
Gao Qiu
Xiangying Liu
Quanwei Xie
Zonghao Lin
Feng Wang
Lei Cai

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1559022

3,698 views
2 citations

Original Research

Published on 25 Apr 2025

The immunostimulatory activity of Epimedium flavonoids involves toll-like receptor 7/8

in Inflammation Pharmacology

Jingyu Wu
Yi Ou
Min Yao
Jiaquan Liu
Hengxing Ran
Zhengrong Wu
Rihui Wu
Lishe Gan
Dongli Li
Jingwei Jin

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1514284

2,325 views
2 citations

Original Research

Published on 25 Apr 2025

Frailty and cardiovascular safety of JAK inhibitors versus TNF inhibitors in rheumatoid arthritis: a real-world comparative study of drug effects and patient profiles

in Inflammation Pharmacology

Ettore Silvagni
Alessandra Bortoluzzi
Giuseppe Occhino
Giuseppe Bellelli
Carlo Garaffoni
Paolo Delvino
Olivia Leoni
Maria Grazia Valsecchi
Carlo Alberto Scirè
Paola Rebora

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1565909

3,676 views
5 citations

Editorial

Published on 25 Apr 2025

Editorial: Targeting neuroinflammation for novel therapeutics in neurodegenerative diseases

in Inflammation Pharmacology

Pukar Khanal
Rupesh Chikhale
Jatin Machhi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1602495

2,963 views

Original Research

Published on 24 Apr 2025

S1PR4-dependent effects of Etrasimod on primary human myeloid immune cell activation

in Inflammation Pharmacology

Fiona K. Sailer
Megan A. Palmer
Blerina Aliraj
Jan Heering
Andreas Brockmann
Mohammed A. F. Elewa
Aissa Röhrig
Ewgenij Proschak
Dariusz T. Stepniak
Simeon Ramsey

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1590816

3,995 views

Original Research

Published on 23 Apr 2025

Tetramethylpyrazine alleviates acute pancreatitis inflammation by inhibiting pyroptosis via the NRF2 pathway

in Inflammation Pharmacology

Huangen Li
Yi Gao
Minglian Huang
Hongling Zhang
Qingqing Wu
Youpei Huang
Xiaotong Ye
Weiwen Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1557681

2,159 views
3 citations

Original Research

Published on 23 Apr 2025

An off-target effect of class A CpG-oligonucleotides on suppressing the cyclic GMP-AMP synthase signaling in fibroblastic reticular cells

in Inflammation Pharmacology

Preethi Jayakumar
Ting Jiang
Hai Huang
Meihong Deng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1576151

1,973 views

1,832 articles

articles

Biodegradable sustained-release microneedle patch loaded with clindamycin hydrochloride: a breakthrough in acne management

Determination of nine prostaglandins in the arachidonic acid metabolic pathway with UHPLC-QQQ-MS/MS and application to in vitro and in vivo inflammation models

Blockade of IL-1 family cytokines in the treatment of rheumatoid arthritis

Macrophage polarization in disease therapy: insights from astragaloside IV and cycloastragenol

The key players of inflammasomes and pyroptosis in sepsis-induced pathogenesis and organ dysfunction

Immunopharmacology of gastric cancer–deciphering immune cell subset responses and nanoparticle-mediated targeting

Editorial: Inflammation and lipid signaling in disease pathogenesis

Associations between ionomic profile and metabolic abnormalities in a murine model of sodium sulfide induced alopecia areata

The green tea component (−)-epigallocatechin-3-gallate protects against cytokine-induced epithelial barrier damage in intestinal epithelial cells

Corrigendum: C16 peptide promotes vascular growth and reduces inflammation in a neuromyelitis optica model

Esmolol improves sepsis outcomes through cardiovascular and immune modulation

Suppressing chondrocyte cuproptosis by syringaresinol-4-O-β-d-glucoside alleviates gouty arthritis

Natural saponins and macrophage polarization: Mechanistic insights and therapeutic perspectives in disease management

Rutin ameliorates LPS-induced acute lung injury in mice by inhibiting the cGAS-STING-NLRP3 signaling pathway

Curcumin: a potential anti-photoaging agent

Effect of methotrexate/dexamethasone combination on epithelial-mesenchymal transition and inflammation gene expression of human RPE cells in-vitro

Irisin restrains neuroinflammation in mouse experimental autoimmune encephalomyelitis via regulating microglia activation

Anti-inflammatory effect and mechanism of stytontriterpene D on RAW264.7 cells and zebrafish

The immunostimulatory activity of Epimedium flavonoids involves toll-like receptor 7/8

Frailty and cardiovascular safety of JAK inhibitors versus TNF inhibitors in rheumatoid arthritis: a real-world comparative study of drug effects and patient profiles

Editorial: Targeting neuroinflammation for novel therapeutics in neurodegenerative diseases

S1PR4-dependent effects of Etrasimod on primary human myeloid immune cell activation

Tetramethylpyrazine alleviates acute pancreatitis inflammation by inhibiting pyroptosis via the NRF2 pathway

An off-target effect of class A CpG-oligonucleotides on suppressing the cyclic GMP-AMP synthase signaling in fibroblastic reticular cells