Frontiers in Pharmacology | Inflammation Pharmacology

Original Research

Published on 25 Jun 2025

Dexmedetomidine reduces acute lung injury caused by LPS through the SIRT3 signaling pathway in vivo

in Inflammation Pharmacology

Jian Chen
Yang Cai
Xiaochun Peng
Yuanling Xu
Liying Chen
Xinxin Pan
Yingying Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1524219

1,755 views

Systematic Review

Published on 23 Jun 2025

Safety profile and dose-dependent adverse events of upadacitinib in randomized clinical trials: a systematic review and meta-analysis

in Inflammation Pharmacology

Cong Zhang
Zhiwen Fu
Jinmei Liu
Shijun Li
Xu Chen
Yi Zhang
Jiyi Xie

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1598972

5,949 views
4 citations

Editorial

Published on 19 Jun 2025

Editorial: Purinergic signaling in metabolic diseases and inflammation pharmacology

in Inflammation Pharmacology

Alejandro Sánchez-Melgar
Juana Maria Sanz
Anna Lisa Giuliani

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1631388

1,882 views
1 citation

Original Research

Published on 18 Jun 2025

Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition

in Inflammation Pharmacology

Yuhui Zhang
Qiguang Wu
Yanjin Pan
Min Xin
Wenbo Wang
Xiaoya Zhai
Peiquan Zhou
Chong Zhang
Yong Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1596087

3,499 views
2 citations

Original Research

Published on 18 Jun 2025

SIRT2-dependent CPT1A deacetylation in macrophages inhibits periodontitis

in Inflammation Pharmacology

Yixuan Jiang
Xiu Yao
Zhizhong Jiang
Xiaomeng Liu
Boyuan Sun
Zhengyu Guan
Lin Zhou
Hongjiao Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1574141

2,800 views

Correction

Published on 17 Jun 2025

Correction: Ginsenoside compound K attenuates Ox-LDL-mediated macrophage inflammation and foam cell formation via autophagy induction and modulating NF-κB, p38, and JNK MAPK signaling

in Inflammation Pharmacology

Shan Lu
Yun Luo
GuiBo Sun
XiaoBo Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1499242

1,683 views

Original Research

Published on 13 Jun 2025

AduCPI2 alleviates MSU-induced acute gouty arthritis in mice by inhibiting cathepsin S and the C5a-C5aR1 axis

in Inflammation Pharmacology

Sijing Liu
Yongli Situ
Li Deng
Meng Liang
Haoyuan He
Zheng Shao
Lifei Peng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1604329

2,539 views

Review

Published on 13 Jun 2025

Salt sensitivity and myocardial fibrosis: unraveling the silent cardiovascular remodeling

in Inflammation Pharmacology

Katongo Hope Mutengo
Owen Ngalamika
Annet Kirabo
Sepiso K. Masenga

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1626492

3,706 views
3 citations

Original Research

Published on 11 Jun 2025

Urinary urodilatin levels in patients with renal salt wasting syndrome as a possible new diagnostic marker. A pilot study

in Inflammation Pharmacology

Vittoriano Della Corte
Luisa Agnello
Rosario Norrito
Marco Cataldi
Fabio Del Ben
Rosaria Pecoraro
Carlo Maida
Caterina Maria Gambino
Mario Daidone
Rosaria Vincenza Giglio

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1579699

1,684 views

Mini Review

Published on 10 Jun 2025

Cytokine release syndrome and CAR T Cell therapy: Modulating the intensity of the inflammatory response and resolution within the tumor microenvironment

in Inflammation Pharmacology

David F. Driscoll
Bruce R. Bistrian

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1615526

3,587 views
3 citations

Systematic Review

Published on 10 Jun 2025

Effects of dupilumab on quality of life in patients with atopic dermatitis: a systematic review and meta-analysis of randomized controlled trials

in Inflammation Pharmacology

Yunqing Sun
Haibo Liu
Yingjun Gao
Hong Sang
Qingtao Kong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1587977

5,370 views
7 citations

Systematic Review

Published on 09 Jun 2025

Comparative effectiveness and safety of tofacitinib vs. adalimumab in patients with rheumatoid arthritis: A systematic review and meta-analysis

in Inflammation Pharmacology

Chunyan Zhu
Yibo Zheng
Zilu Wang
Guozong Chen
Yushi Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1524214

3,777 views

Review

Published on 09 Jun 2025

Targeting the cGAS-STING pathway: emerging strategies and challenges for the treatment of inflammatory skin diseases

in Inflammation Pharmacology

Haoyun Luo
Tian Tian
Chenmin Hu
Fei Hao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1597443

4,612 views
4 citations

Original Research

Published on 05 Jun 2025

Erdafitinib diminishes LPS-mediated neuroinflammatory responses through NLRP3 in wild-type mice

in Inflammation Pharmacology

Hyun-ju Lee
Se Ha Kim
Tae-Mi Jung
Yu-Jin Kim
Chan-Hu Gu
Yoo Joo Jeong
Jeong-Heon Song
Hyang-Sook Hoe

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1572604

3,887 views
1 citation

Original Research

Published on 30 May 2025

Biodegradable sustained-release microneedle patch loaded with clindamycin hydrochloride: a breakthrough in acne management

in Inflammation Pharmacology

Haomei Fan
Ruohan Liao
Yiling Yang
Yan Xing
Chengdong Zhang
Xuwei Luo
Chao Pu
Liling Wu
Xingping Li
Juhua Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1575635

4,972 views
1 citation

Original Research

Published on 30 May 2025

Determination of nine prostaglandins in the arachidonic acid metabolic pathway with UHPLC-QQQ-MS/MS and application to in vitro and in vivo inflammation models

in Inflammation Pharmacology

Yufeng Huang
Mengxian Wang
Ziqi Yang
Xiaotong Wang
Xinxin Wang
Fan He

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1595059

2,926 views

Review

Published on 30 May 2025

Blockade of IL-1 family cytokines in the treatment of rheumatoid arthritis

in Inflammation Pharmacology

Kexin Wang
Haoge Luo
Liping Liu
Hang Gao
Yanyan Song
Dong Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1577628

6,112 views
11 citations

Review

Published on 23 May 2025

Macrophage polarization in disease therapy: insights from astragaloside IV and cycloastragenol

in Inflammation Pharmacology

Bei-Bei Xiong
Yu-Mei Zhuo
Huan Wang
Qiao-Ling Zheng
Feng Tang
Qun Huang
Man Yao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1598022

4,927 views
5 citations

Review

Published on 19 May 2025

The key players of inflammasomes and pyroptosis in sepsis-induced pathogenesis and organ dysfunction

in Inflammation Pharmacology

Lujian Zhu
Minli Hu
Haoming Xu
Hanglu Xu
Binbin Ren
Ruiyan Xu
Maodong Guo
Haijun Chen
Dehe Zhang
Hao Fang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1586364

3,851 views
3 citations

Review

Published on 19 May 2025

Immunopharmacology of gastric cancer–deciphering immune cell subset responses and nanoparticle-mediated targeting

in Inflammation Pharmacology

Yanting Wang
Ning Ding
Lina Qi
Wenwen Chen
Panyisha Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1611234

2,801 views
3 citations

Editorial

Published on 16 May 2025

Editorial: Inflammation and lipid signaling in disease pathogenesis

in Inflammation Pharmacology

Paola Patrignani
Bernhard Brüne
Angelo Sala
Pietro Minuz
Dieter Steinhilber

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1623707

1,911 views

Original Research

Published on 14 May 2025

The green tea component (−)-epigallocatechin-3-gallate protects against cytokine-induced epithelial barrier damage in intestinal epithelial cells

in Inflammation Pharmacology

Rita Rosenthal
Anne Waesch
Kopano Valerie Masete
Alain S. Massarani
Jörg-Dieter Schulzke
Nina A. Hering

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1559812

4,337 views
4 citations

Original Research

Published on 14 May 2025

Associations between ionomic profile and metabolic abnormalities in a murine model of sodium sulfide induced alopecia areata

in Inflammation Pharmacology

Luning Li
Zhen Sun
Wenxue Sun
Yujuan Zhai
Na Ding
Wei Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1507348

2,555 views

Correction

Published on 13 May 2025

Corrigendum: C16 peptide promotes vascular growth and reduces inflammation in a neuromyelitis optica model

in Inflammation Pharmacology

Haohao Chen
Xiaoxiao Fu
Jinzhan Jiang
Shu Han

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1611115

1,456 views

1,846 articles

articles

Dexmedetomidine reduces acute lung injury caused by LPS through the SIRT3 signaling pathway in vivo

Safety profile and dose-dependent adverse events of upadacitinib in randomized clinical trials: a systematic review and meta-analysis

Editorial: Purinergic signaling in metabolic diseases and inflammation pharmacology

Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition

SIRT2-dependent CPT1A deacetylation in macrophages inhibits periodontitis

Correction: Ginsenoside compound K attenuates Ox-LDL-mediated macrophage inflammation and foam cell formation via autophagy induction and modulating NF-κB, p38, and JNK MAPK signaling

AduCPI2 alleviates MSU-induced acute gouty arthritis in mice by inhibiting cathepsin S and the C5a-C5aR1 axis

Salt sensitivity and myocardial fibrosis: unraveling the silent cardiovascular remodeling

Urinary urodilatin levels in patients with renal salt wasting syndrome as a possible new diagnostic marker. A pilot study

Cytokine release syndrome and CAR T Cell therapy: Modulating the intensity of the inflammatory response and resolution within the tumor microenvironment

Effects of dupilumab on quality of life in patients with atopic dermatitis: a systematic review and meta-analysis of randomized controlled trials

Comparative effectiveness and safety of tofacitinib vs. adalimumab in patients with rheumatoid arthritis: A systematic review and meta-analysis

Targeting the cGAS-STING pathway: emerging strategies and challenges for the treatment of inflammatory skin diseases

Erdafitinib diminishes LPS-mediated neuroinflammatory responses through NLRP3 in wild-type mice

Biodegradable sustained-release microneedle patch loaded with clindamycin hydrochloride: a breakthrough in acne management

Determination of nine prostaglandins in the arachidonic acid metabolic pathway with UHPLC-QQQ-MS/MS and application to in vitro and in vivo inflammation models

Blockade of IL-1 family cytokines in the treatment of rheumatoid arthritis

Macrophage polarization in disease therapy: insights from astragaloside IV and cycloastragenol

The key players of inflammasomes and pyroptosis in sepsis-induced pathogenesis and organ dysfunction

Immunopharmacology of gastric cancer–deciphering immune cell subset responses and nanoparticle-mediated targeting

Editorial: Inflammation and lipid signaling in disease pathogenesis

The green tea component (−)-epigallocatechin-3-gallate protects against cytokine-induced epithelial barrier damage in intestinal epithelial cells

Associations between ionomic profile and metabolic abnormalities in a murine model of sodium sulfide induced alopecia areata

Corrigendum: C16 peptide promotes vascular growth and reduces inflammation in a neuromyelitis optica model