Frontiers in Pharmacology | Integrative and Regenerative Pharmacology

Review

Published on 03 Sep 2025

Efficacy of platelet-rich plasma injection with percutaneous endoscopic lumbar discectomy for lumbar disc herniation: a systematic review and meta-analysis

in Integrative and Regenerative Pharmacology

Yu Zhang
Jidong Ju
Jinchun Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1622974

4,811 views
2 citations

Original Research

Published on 28 Aug 2025

A comprehensive bibliometric exploration of hydrogel applications in spinal cord injury

in Integrative and Regenerative Pharmacology

Guosong Han
Huihui Zhang
Zhixiang Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1606186

2,626 views

Original Research

Published on 21 Aug 2025

2′-Fucosyllactose mitigates cognitive deficits in Alzheimer models: targeting amyloid pathology, oxidative stress, and synaptic plasticity

in Integrative and Regenerative Pharmacology

Yeasmin Akter Munni
Khoa Nguyen Tran
Seon-Min Jeon
Meeyul Hwang
Jong-Won Yoon
Young-Ha Song
Tae Woo Oh
Sang Il Gum
In-Jun Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1598030

3,120 views

Original Research

Published on 30 Jun 2025

Narirutin treatment accelerates the process of diabetic wound repair by regulating phenotype switching of macrophages through affecting metabolic reprogramming

in Integrative and Regenerative Pharmacology

Liang Liu
Han Wang
Juan Zhou
Jing Lu
Yan Zhang
Haiyan Liu
Li Lu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1614967

2,995 views
2 citations

Review

Published on 24 Jun 2025

Advances in hydrogel-based materials for breast cancer bone metastasis: from targeted drug delivery to bone microenvironment remodeling

in Integrative and Regenerative Pharmacology

Jiayi Chen
Jun Ma
Zhuoming Xu
Huanhuan Luo
Chenhong Qian

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1627883

2,832 views
1 citation

Review

Published on 24 Jun 2025

The impacts of natural polyphenols and exercise alone or together on microRNAs and angiogenic signaling

in Integrative and Regenerative Pharmacology

Yanna Sun
Linlin Chen
Lili Xiao
Xiaofang Wang
Jamal Hallajzadeh

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1560305

2,338 views

Review

Published on 18 Jun 2025

Recent advances in dermal fibroblast senescence and skin aging: unraveling mechanisms and pioneering therapeutic strategies

in Integrative and Regenerative Pharmacology

Li Nan
Pengchao Guo
Wang Hui
Fang Xia
Chenggang Yi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1592596

11,993 views
14 citations

Correction

Published on 16 Jun 2025

Correction: Biomineralized composite liquid crystal fiber scaffold promotes bone regeneration by enhancement of osteogenesis and angiogenesis

in Integrative and Regenerative Pharmacology

Yi Zhan
Bing Deng
Huixian Wu
Changpeng Xu
Ruiying Wang
Wenqiang Li
Zhixiong Pan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1617849

874 views

Original Research

Published on 04 Jun 2025

BaDuShengJi hydrogel accelerates diabetic wounds healing and regeneration of deep burn injury by anti-bacteria, anti-inflammation and promoting epithelialization

in Integrative and Regenerative Pharmacology

Yuxiang Zhang
Yuanyuan Yu
Lien Yu
Fang Wang
Fuwei Yang
Shiyu Liang
Wen Xu
Mengying Ji
Yinuo Geng
Jingwei Xue

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1580994

2,519 views

Editorial

Published on 30 May 2025

Editorial: Latest advancements in organ-on-a-chip technology

in Integrative and Regenerative Pharmacology

Jareer Kassis
Zhengpeng Wan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1631320

3,564 views
1 citation

Editorial

Published on 30 Apr 2025

Editorial: Integrative pharmacological approaches for regenerating cartilage and bone tissue

in Integrative and Regenerative Pharmacology

Jiahui Tan
Jie Fang
Wen Liao
Lufei Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1613512

1,734 views

Original Research

Published on 30 Apr 2025

Multifunctional PdH-hydride MOFs for synergistic hydrogen and photothermal antibacterial therapy in accelerated wound healing

in Integrative and Regenerative Pharmacology

Qing Wang
Daixing Zhang
Yining Qi
Changbao Huang
Dejun Ding
Chuanliang Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1587890

2,140 views

Original Research

Published on 28 Apr 2025

The impact of remimazolam sedation during neuraxial anesthesia on perioperative cognitive function in elderly patients: a multicenter randomized controlled study

in Integrative and Regenerative Pharmacology

Dan Qiao
Jia-Min Kang
Rui Zhang
Lin-Yue Zong
Ying Xu
Wei-Wei Zhang
Qi Zhou
Yan Li
Tao Han
Yue-Ming Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1504813

2,817 views
1 citation

Original Research

Published on 23 Apr 2025

LL37 promotes angiogenesis: a potential therapeutic strategy for lower limb ischemic diseases

in Integrative and Regenerative Pharmacology

Yingying Yang
Gang Wu
Yini Wang
Qiancheng Mao
Dongxu Zhang
Jitao Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1587351

2,777 views
3 citations

Editorial

Published on 22 Apr 2025

Editorial: Mobilization of hematopoietic cells from the bone marrow to the peripheral blood: Challenges and new therapeutic targets

in Integrative and Regenerative Pharmacology

Agata Szade
Gunsagar S. Gulati
Agnieszka D. Czechowicz

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1592559

2,024 views

Review

Published on 16 Apr 2025

Natural small molecules regulating the mitophagy pathway counteract the pathogenesis of diabetes and chronic complications

in Integrative and Regenerative Pharmacology

Du Ye
Junping Zhu
Siya Su
Yunfeng Yu
Jun Zhang
Yuman Yin
Chuanquan Lin
Xuejiao Xie
Qin Xiang
Rong Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1571767

4,656 views
4 citations

Original Research

Published on 09 Apr 2025

Microfluidic chip-based co-culture system for modeling human joint inflammation in osteoarthritis research

in Integrative and Regenerative Pharmacology

Hosein Mirazi
Scott T. Wood

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1579228

3,478 views
5 citations

Review

Published on 31 Mar 2025

The status and hotspot analysis of research on extracellular vesicles and osteoarthritis: a bibliometric analysis

in Integrative and Regenerative Pharmacology

Wen Hao Zhang
Wen Yuan Xiang
Lin Yi
Rui Fang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1484437

3,548 views
2 citations

Original Research

Published on 27 Mar 2025

Silk fibroin–collagen hydrogel loaded with IGF1-CESCs attenuates intervertebral disk degeneration by accelerating annulus fibrosus healing in rats

in Integrative and Regenerative Pharmacology

Zhiqiang Tian
Zigang Shen
Hong Chen
Ping Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1552174

3,081 views
3 citations

Original Research

Published on 25 Mar 2025

Thymoquinone alleviates the accumulation of ROS and pyroptosis and promotes perforator skin flap survival through SIRT1/NF-κB pathway

in Integrative and Regenerative Pharmacology

Jianxin Yang
Haojie Zhang
Libin Ni
Jun He

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1567762

1,897 views
1 citation

Original Research

Published on 18 Mar 2025

Rapid in situ formation of a double cross-linked network hydrogels for wound healing promotion

in Integrative and Regenerative Pharmacology

Yifan Liu
Ye Zhang
Qianqian Jia
Xiaoyun Liang
Kejin Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1562264

2,718 views
1 citation

Original Research

Published on 13 Mar 2025

A bibliometric and visualized analysis of extracellular vesicles in degenerative musculoskeletal diseases (from 2006 to 2024)

in Integrative and Regenerative Pharmacology

Jun-Jie Yang
Sha-Qi He
Bei Huang
Peng-Xin Wang
Feng Xu
Xiao Lin
Jun Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1550208

3,106 views
1 citation

Review

Published on 13 Mar 2025

Engineered stromal vascular fraction for tissue regeneration

in Integrative and Regenerative Pharmacology

Jianfeng Liu
Yiwei Li
Yanan Zhang
Zhiwei Zhao
Bin Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1510508

4,007 views
4 citations

Original Research

Published on 10 Mar 2025

Sodium alginate hydrogel loaded with upconversion nanoparticles and magnesium ions enhances bone regeneration and photodynamic tumor therapy

in Integrative and Regenerative Pharmacology

Siyu Song
Xirao Sun
Yanfu Wang
Meng Wang
Zheng Shi
Danfang Sun
Dan Li
Jianduo Chen
Chengyue Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1543678

2,406 views
1 citation