Frontiers in Pharmacology | Integrative and Regenerative Pharmacology

Original Research

Published on 17 Jun 2022

Valorization of Polysaccharides From Benincasa hispida: Physicochemical, Moisturizing, and Antioxidant Skincare Properties

in Integrative and Regenerative Pharmacology

Qian Wang
Xiaoyan Yang
Changwei Zhu
Guodong Liu
Weili Han
Yujun Sun
Lisheng Qian

Frontiers in Pharmacology

doi 10.3389/fphar.2022.912382

7,138 views
15 citations

Original Research

Published on 15 Jun 2022

Antisense Oligonucleotide-Based Therapy on miR-181a-5p Alleviates Cartilage Degradation of Temporomandibular Joint Osteoarthritis via Promoting SIRT1

in Integrative and Regenerative Pharmacology

Hexu Qi
Zhenxing Zhao
Lin Xu
Yue Zhang
Yifei Li
Li Xiao
Yu Li
Zhihe Zhao
Jie Fang

Frontiers in Pharmacology

doi 10.3389/fphar.2022.898334

4,596 views
10 citations

Original Research

Published on 27 May 2022

Hyaluronic Acid Hydrogels Hybridized With Au-Triptolide Nanoparticles for Intraarticular Targeted Multi-Therapy of Rheumatoid Arthritis

in Integrative and Regenerative Pharmacology

Chenxi Li
Rui Liu
Yurong Song
Youwen Chen
Dongjie Zhu
Liuchunyang Yu
Qingcai Huang
Zhengjia Zhang
Zeyu Xue
Zhenglai Hua

Frontiers in Pharmacology

doi 10.3389/fphar.2022.849101

5,781 views
20 citations

Review

Published on 20 May 2022

The Prospective Application of Melatonin in Treating Epigenetic Dysfunctional Diseases

in Integrative and Regenerative Pharmacology

Seth Mikaye Monayo
Xin Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2022.867500

5,928 views
14 citations

Review

Published on 11 May 2022

Assessment of the Therapeutic Potential of Melatonin for the Treatment of Osteoporosis Through a Narrative Review of Its Signaling and Preclinical and Clinical Studies

in Integrative and Regenerative Pharmacology

Yongchao Zhao
Guoxi Shao
Xingang Liu
Zhengwei Li

Frontiers in Pharmacology

doi 10.3389/fphar.2022.866625

8,966 views
16 citations

Review

Published on 04 May 2022

The Role of Geranylgeraniol in Managing Bisphosphonate-Related Osteonecrosis of the Jaw

in Integrative and Regenerative Pharmacology

Kok-Yong Chin
Sophia Ogechi Ekeuku
Anne Trias

Frontiers in Pharmacology

doi 10.3389/fphar.2022.878556

6,695 views
11 citations

Original Research

Published on 06 Apr 2022

Evaluating Osteogenic Differentiation of Osteoblastic Precursors Upon Intermittent Administration of PTH/IGFBP7

in Integrative and Regenerative Pharmacology

Han Xia
Yueyang Tian
Yile Lin
Qia Huang
Yuan Xue

Frontiers in Pharmacology

doi 10.3389/fphar.2022.839035

3,065 views
9 citations

Original Research

Published on 31 Mar 2022

Hormone Therapy: A Potential Risk Factor Affecting Survival and Functional Restoration of Transplanted Lymph Nodes

in Integrative and Regenerative Pharmacology

Dong Dong
Heng Wang
Liang Chen
Wei Wang
Tianyi Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2022.853859

4,292 views
1 citation

Original Research

Published on 23 Mar 2022

Chrysin Protects Against Titanium Particle-Induced Osteolysis by Attenuating Osteoclast Formation and Function by Inhibiting NF-κB and MAPK Signaling

in Integrative and Regenerative Pharmacology

Zuoxing Wu
Chen Li
Yu Chen
Qian Liu
Na Li
Xuemei He
Weibin Li
Rong Shen
Li Li
Chenming Wei

Frontiers in Pharmacology

doi 10.3389/fphar.2022.793087

5,342 views
24 citations

Original Research

Published on 22 Mar 2022

Therapeutic Efficacy of Intravesical Platelet-Rich Plasma Injections for Interstitial Cystitis/Bladder Pain Syndrome—A Comparative Study of Different Injection Number, Additives and Concentrations

in Integrative and Regenerative Pharmacology

Yuan-Hong Jiang
Jia-Fong Jhang
Teng-Yi Lin
Han-Chen Ho
Yung-Hsiang Hsu
Hann-Chorng Kuo

Frontiers in Pharmacology

doi 10.3389/fphar.2022.853776

9,352 views
15 citations

Original Research

Published on 21 Mar 2022

Intra-Articular Injection of Adipose-Derived Stem Cells Ameliorates Pain and Cartilage Anabolism/Catabolism in Osteoarthritis: Preclinical and Clinical Evidences

in Integrative and Regenerative Pharmacology

Bo Yan
Shuaijie Lv
Peijian Tong
Li Yan
Zuxiang Chen
Li Zhou
Qiang Yuan
Le Guo
Letian Shan

Frontiers in Pharmacology

doi 10.3389/fphar.2022.854025

9,238 views
30 citations

Original Research

Published on 14 Mar 2022

Urolithin A Promotes Angiogenesis and Tissue Regeneration in a Full-Thickness Cutaneous Wound Model

in Integrative and Regenerative Pharmacology

Zhen-hua Feng
Jia Chen
Pu-tao Yuan
Zhong-yin Ji
Si-yue Tao
Lin Zheng
Xiao-an Wei
Ze-yu Zheng
Bing-jie Zheng
Bin Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2022.806284

8,094 views
11 citations

Review

Published on 28 Feb 2022

Roles of MicroRNA-21 in Skin Wound Healing: A Comprehensive Review

in Integrative and Regenerative Pharmacology

Jie Xie
Weizhou Wu
Liying Zheng
Xuesong Lin
Yuncheng Tai
Yajie Wang
Le Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2022.828627

11,738 views
63 citations

Original Research

Published on 22 Feb 2022

Metformin Alleviates Endometriosis and Potentiates Endometrial Receptivity via Decreasing VEGF and MMP9 and Increasing Leukemia Inhibitor Factor and HOXA10

in Integrative and Regenerative Pharmacology

Jing Cheng
Chunyang Li
Yingfen Ying
Jieqiang Lv
Xianqin Qu
Eileen McGowan
Yiguang Lin
Xueqiong Zhu

Frontiers in Pharmacology

doi 10.3389/fphar.2022.750208

13,331 views
33 citations

Original Research

Published on 08 Feb 2022

The Efficacy and Mid-term Durability of Urethral Sphincter Injections of Platelet-Rich Plasma in Treatment of Female Stress Urinary Incontinence

in Integrative and Regenerative Pharmacology

Ching-Hsiang Chiang
Hann-Chorng Kuo

Frontiers in Pharmacology

doi 10.3389/fphar.2022.847520

7,100 views
22 citations

Original Research

Published on 05 Jan 2022

Biphasic Effect of Pirfenidone on Angiogenesis

in Integrative and Regenerative Pharmacology

Donghao Gan
Wenxiang Cheng
Liqing Ke
Antonia RuJia Sun
Qingyun Jia
Jianhai Chen
Zhanwang Xu
Juan Xu
Peng Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2021.804327

4,123 views
14 citations

Original Research

Published on 03 Jan 2022

Mapping Thematic Trends and Analysing Hotspots Concerning the Use of Stem Cells for Cartilage Regeneration: A Bibliometric Analysis From 2010 to 2020

in Integrative and Regenerative Pharmacology

Demeng Xia
Jianghong Wu
Feng Zhou
Sheng Wang
Zhentao Zhang
Panyu Zhou
Shuogui Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2021.737939

6,685 views
13 citations

Original Research

Published on 14 Dec 2021

The Attenuating Effect of Low-Intensity Pulsed Ultrasound on Hypoxia-Induced Rat Chondrocyte Damage in TMJ Osteoarthritis Based on TMT Labeling Quantitative Proteomic Analysis

in Integrative and Regenerative Pharmacology

Sa Du
Chao Liang
Yujie Sun
Bowen Ma
Wenmo Gao
Wei Geng

Frontiers in Pharmacology

doi 10.3389/fphar.2021.752734

5,068 views
8 citations

Original Research

Published on 30 Nov 2021

ERα-Targeting PROTAC as a Chemical Knockdown Tool to Investigate the Estrogen Receptor Function in Rat Menopausal Arthritis

in Integrative and Regenerative Pharmacology

Li Duan
Xiao Xu
Limei Xu
Caining Wen
Kan Ouyang
Zigang Li
Yujie Liang

Frontiers in Pharmacology

doi 10.3389/fphar.2021.764154

4,962 views
6 citations

Original Research

Published on 25 Nov 2021

Anti-Osteogenic Effect of Danshensu in Ankylosing Spondylitis: An in Vitro Study Based on Integrated Network Pharmacology

in Integrative and Regenerative Pharmacology

Jiaxiao Li
Zexin Chen
Hongbo Liao
Yanting Zhong
Junying Hua
Miaoling Su
Jiahao Li
Jinrong Xu
Liao Cui
Yang Cui

Frontiers in Pharmacology

doi 10.3389/fphar.2021.772190

4,015 views
11 citations

Original Research

Published on 24 Nov 2021

A Core Omnigenic Non-coding Trait Governing Dex-Induced Osteoporotic Effects Identified Without DEXA

in Integrative and Regenerative Pharmacology

Li Lu
Yanzhen Cai
Xiaoling Luo
Zhangting Wang
Sin Hang Fung
Huanhuan Jia
Chi Lam Yu
Wai Yee Chan
Kai Kei Miu
Wende Xiao

Frontiers in Pharmacology

doi 10.3389/fphar.2021.750959

3,267 views
2 citations

Review

Published on 23 Nov 2021

Recent Advances in Pharmacological Intervention of Osteoarthritis: A Biological Aspect

in Integrative and Regenerative Pharmacology

Jinxia Deng
Zhixian Zong
Zhanpeng Su
Haicong Chen
Jianping Huang
Yanru Niu
Huan Zhong
Bo Wei

Frontiers in Pharmacology

doi 10.3389/fphar.2021.772678

8,068 views
12 citations

Original Research

Published on 08 Nov 2021

Biomineralized Composite Liquid Crystal Fiber Scaffold Promotes Bone Regeneration by Enhancement of Osteogenesis and Angiogenesis

in Integrative and Regenerative Pharmacology

Yi Zhan
Bing Deng
Huixian Wu
Changpeng Xu
Ruiying Wang
Wenqiang Li
Zhixiong Pan

Frontiers in Pharmacology

doi 10.3389/fphar.2021.736301

3,593 views
8 citations

Original Research

Published on 04 Nov 2021

(-)-Epigallocatechin-3-gallate Ameliorates Intervertebral Disc Degeneration Through Reprogramming of the Circadian Clock

in Integrative and Regenerative Pharmacology

Liangwei Mei
Yi Zheng
Teng Ma
Bing Xia
Xue Gao
Yiming Hao
Zhuojing Luo
Jinghui Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2021.753548

4,670 views
15 citations