Frontiers in Pharmacology | Neuropharmacology

Original Research

Published on 13 Mar 2025

A real-world safety surveillance study of aducanumab through the FDA adverse event reporting system

in Neuropharmacology

Jingjing Huang
Xiaohong Long
Chunyong Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1522058

101 views

Original Research

Published on 13 Mar 2025

Randomized crossover clinical studies to assess abuse liability and nicotine pharmacokinetics of Velo Oral Nicotine pouches

in Neuropharmacology

Milly N. Kanobe
Christie Y. Powell
Makena Patrudu
Sarah A. Baxter
Melissa A. Tapia
John Darnell
Kristen Prevette
Alison G. Gibson
Sarah A. Ayoku
Leanne Campbell

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1547073

151 views

Review

Published on 13 Mar 2025

Crosstalk between neuroinflammation and ferroptosis: Implications for Parkinson’s disease progression

in Neuropharmacology

Xiangyu Guo
Ran Wei
Xunzhe Yin
Ge Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1528538

Original Research

Published on 12 Mar 2025

Vortioxetine alleviates motor, cognitive and emotional disorders in post-stroke rats by regulating the TLR-2/NF-κB pathway

in Neuropharmacology

Ziqiang Dong
Zhihui Dong
Lili Xu
Jinfeng Zhang
Lin Li
Rongjuan Wang
Xiaoyan Huang
Zhengqiang Zou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1555079

137 views

Original Research

Published on 12 Mar 2025

Assessing the effects of antidepressant use on stroke recurrence and related outcomes in ischemic stroke patients: a propensity score matched analysis

in Neuropharmacology

Faisal F. Alamri
Daniyah A. Almarghalani
Yasser Alatawi
Eman A. Alraddadi
Omar Babateen
Ahmed Alayyafi
Ziyad Almalki
Khaled Alsalhi
Khaled Alzahrani
Ahmed Alghamdi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1558703

142 views

Original Research

Published on 11 Mar 2025

Zingerone alleviates inflammatory pain by reducing the intrinsic excitability of anterior cingulate cortex neurons in a mice model

in Neuropharmacology

Yuanyuan Wang
Lang Dong
Shu Han
Yuehan You
Mingrui Zhang
Bingjing Sun
Hong Ni
Rongjing Ge
Jianhong Liu
Jiandong Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1543594

158 views

Original Research

Accepted on 10 Mar 2025

Brosimine B and the Biphasic Dose-Response: Insights into Hormesis and Retinal Neuroprotection

in Neuropharmacology

Susanne Suely Santos da Fonseca
Natacha Medeiros de Souza Port's
Gisele Priscila Soares de Aguiar
Eliã Pinheiro Botelho
Nádia Miléo Garcês de Couto
Wandson Braamcamp de Souza Pinheiro
André Salim Khayat
Elizabeth Sumi Yamada
Edmar Tavares da Costa
Chubert Bernardo Castro de Sena

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1558726

Review

Accepted on 10 Mar 2025

Natural products protect against spinal cord injury by inhibiting ferroptosis: A literature review

in Neuropharmacology

Wei She
Su Junxiao
Wenji Ma
Guohai Ma
Jianfu Li
Hui Zhang
Cheng Qiu
Xingyong Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1557133

Original Research

Published on 07 Mar 2025

α-Bisabolol alleviates doxorubicin-induced cognitive dysfunction in rats via enhancing the hippocampal BDNF/TrKB signaling and inhibiting neuroinflammation

in Neuropharmacology

Sara T. Elazab
Walter H. Hsu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1549009

214 views

Systematic Review

Accepted on 06 Mar 2025

Neuroprotective effect and possible mechanism of edaravone in rat models of spinal cord injury: a systematic review and network meta-analysis

in Neuropharmacology

Long-yun Zhou
Xiaobo Wang
Xu-qing Chen
Ran Li
Bin-Bin Yu
Meng-Xiao Pan
Lu Fang
Jian Li
Xue-Jun Cui
Min Yao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1538879

Original Research

Accepted on 06 Mar 2025

Indole-3-acetic acid and chenodeoxycholic acid attenuate TLR4/NF-κB signaling and endoplasmic reticulum stress in valproic acid-induced neurotoxicity

in Neuropharmacology

Wedad S Sarawi
Ahlam Mohammed Alhusaini
Ghada S Barwaished
Myasah M Altamimi
Iman H Hasan
Amjad S Aljarboa
Norah K Algarzae
Saleh A Bakheet
Samiah A Alhabardi
Sheikh F Ahmad

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1570125

Systematic Review

Published on 06 Mar 2025

Clinical implications of fracture severity risk with pioglitazone: a systematic review and meta-analysis of clinical randomized trials

in Neuropharmacology

Hala F. Azhari
Jesse Dawson

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1357309

171 views

Original Research

Published on 06 Mar 2025

Marked differences in the effects of levetiracetam and its analogue brivaracetam on microglial, astrocytic, and neuronal density in the rat model of kainic acid-induced temporal lobe epilepsy

in Neuropharmacology

Krisztina Kelemen
Máté Sárosi
Ágnes Csüdör
Károly Orbán-Kis
Hanga Kelemen
László Bába
Zsolt Gáll
Eszter Horváth
István Katona
Tibor Szilágyi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1553545

464 views

Review

Published on 06 Mar 2025

World no-tobacco: effects of second-hand smoke (SHS) and vapors on the developing and adult brain

in Neuropharmacology

Glen Kisby
Jacob Raber

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1466332

204 views

Original Research

Published on 06 Mar 2025

Levodopa-induced motor complications associated with benserazide and carbidopa in Parkinson’s disease: a disproportionality analysis of the FAERS database

in Neuropharmacology

Huaide Qiu
Cheng Liu
Zhixiang Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1529932

794 views

Review

Published on 06 Mar 2025

Histone deacetylases: the critical enzymes for microglial activation involved in neuropathic pain

in Neuropharmacology

Yi Ding

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1515787

168 views

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Articles

A real-world safety surveillance study of aducanumab through the FDA adverse event reporting system

Randomized crossover clinical studies to assess abuse liability and nicotine pharmacokinetics of Velo Oral Nicotine pouches

Crosstalk between neuroinflammation and ferroptosis: Implications for Parkinson’s disease progression

Vortioxetine alleviates motor, cognitive and emotional disorders in post-stroke rats by regulating the TLR-2/NF-κB pathway

Assessing the effects of antidepressant use on stroke recurrence and related outcomes in ischemic stroke patients: a propensity score matched analysis

Zingerone alleviates inflammatory pain by reducing the intrinsic excitability of anterior cingulate cortex neurons in a mice model

Brosimine B and the Biphasic Dose-Response: Insights into Hormesis and Retinal Neuroprotection

Natural products protect against spinal cord injury by inhibiting ferroptosis: A literature review

α-Bisabolol alleviates doxorubicin-induced cognitive dysfunction in rats via enhancing the hippocampal BDNF/TrKB signaling and inhibiting neuroinflammation

Neuroprotective effect and possible mechanism of edaravone in rat models of spinal cord injury: a systematic review and network meta-analysis

Indole-3-acetic acid and chenodeoxycholic acid attenuate TLR4/NF-κB signaling and endoplasmic reticulum stress in valproic acid-induced neurotoxicity

Clinical implications of fracture severity risk with pioglitazone: a systematic review and meta-analysis of clinical randomized trials

Marked differences in the effects of levetiracetam and its analogue brivaracetam on microglial, astrocytic, and neuronal density in the rat model of kainic acid-induced temporal lobe epilepsy

World no-tobacco: effects of second-hand smoke (SHS) and vapors on the developing and adult brain

Levodopa-induced motor complications associated with benserazide and carbidopa in Parkinson’s disease: a disproportionality analysis of the FAERS database

Histone deacetylases: the critical enzymes for microglial activation involved in neuropathic pain