Frontiers in Pharmacology | Neuropharmacology

Original Research

Published on 18 Feb 2026

Peripheral blood RNA-seq analysis in bipolar and schizophrenia spectrum disorders: modest influence of antipsychotic treatment

in Neuropharmacology

Yosra Bejaoui
Suhaila Ghuloum
Teena John
Gaurav Thareja
Tanwir Habib
Karsten Suhre
Hassen Al-Amin

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1745052

240 views

Original Research

Published on 18 Feb 2026

Nervonic acid confers neuroprotection in a zebrafish model of diabetic neuropathy by promoting myelin repair and metabolic modulation

in Neuropharmacology

Huan Ge
Mingzhu Dai
Qinwen Wang
Bingbing Cao
Ximin Zhu
Jie Guo
Tao Zhang
Shasha Wang
Yiqiao Xu
Lushan Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1721486

193 views

Review

Published on 17 Feb 2026

Disruption of estrogen signaling by developmental exposure to BPA and TBT causes long term functional deficits in zebrafish retina

in Neuropharmacology

J. S. Jensen
L. Ouellette
R. Harris
P. Owrang
V. P. Connaughton

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1750796

237 views

Original Research

Accepted on 16 Feb 2026

Comparative pharmacovigilance of non-benzodiazepine receptor agonists versus dual orexin receptor antagonists for insomnia in older adults

in Neuropharmacology

Shuqing Gao
Xiaotang Feng
Qi Li
Jingyi Fan

Frontiers in Pharmacology

Original Research

Accepted on 13 Feb 2026

Antidepressant-like effects of Rg1 by Mycn: promotion of neurogenesis in the hippocampus

in Neuropharmacology

enzhe Shi
yiwei zhang
yan yan Fan
Jiang Fan Chen
linfeng xu
Jiao Chen

Frontiers in Pharmacology

134 views

Editorial

Published on 13 Feb 2026

Editorial: Model organisms in neuropharmacology 2024

in Neuropharmacology

Veronica Rivi
Attila Sik
Cristina Benatti
Alejandra M. Pacchioni

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1800010

250 views

Review

Published on 12 Feb 2026

Dimethyl fumarate and mitochondrial physiology: implications for neurological disorders

in Neuropharmacology

Marcos Roberto de Oliveira

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1748360

378 views

Original Research

Published on 12 Feb 2026

Parabrachial calcitonin gene-related peptide neurons sex-specifically modulate behavior in anxiety assays during alcohol withdrawal

in Neuropharmacology

C. E. Van Doorn
J. B. Tyree
A. A. Jaramillo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1750956

422 views

Mini Review

Accepted on 11 Feb 2026

Bridging the Translational Gap in Systems Neuroscience: From 1 Circuit Mechanisms to Clinical Therapeutics

in Neuropharmacology

Anyin Wang
Jiale Ye
Jie Li
Xiaoqin Chen
Qiaoyan Wang
Kunwei Wu

Frontiers in Pharmacology

225 views

Review

Accepted on 11 Feb 2026

Review of Clinical Advances in the Procedural Sedation Application of Remimazolam

in Neuropharmacology

Shuancheng Bai
奇伟王

Frontiers in Pharmacology

Original Research

Accepted on 11 Feb 2026

Trazodone effectiveness in depression (TED): a comparative evaluation of effect sizes trazodone extended release and SSRIs in the treatment of major depressive disorder

in Neuropharmacology

Dominika Dudek
Adrian Andrzej Chrobak
Karolina Podkowa
Anna Julia Krupa
Aleksandra Gorostowicz
Rafał Jaeschke
Andrzej Juryk
Marcin Siwek

Frontiers in Pharmacology

120 views

Mini Review

Published on 11 Feb 2026

From dopamine to muscarine: xanomeline-trospium (KarXT) as a novel direction in the psychopharmacotherapy of schizophrenia

in Neuropharmacology

Kacper Żełabowski
Wojciech Pichowicz
Julia Dembowska
Maciej Szwajkowski
Daria Mykhailova
Grzegorz Wurm
Kamil Biedka
Katarzyna Błaszczyk
Patryk Piotrowski

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1774437

679 views

Correction

Published on 11 Feb 2026

Correction: Advances in pharmacokinetic-pharmacodynamic modeling for anesthesia, 1987–2024: a review

in Neuropharmacology

Yara Tulbah
Ibrahim Aljamaan

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1804067

269 views

Review

Published on 11 Feb 2026

Review of neuroprotective potential of natural products against hypoxia-induced neuronal injury

in Neuropharmacology

Yuman Zhang
Xingyu Yi
Dingzhong Wang
Cunlong Kong
Yan Xu
Jianping Xie

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1746683

340 views

Original Research

Published on 10 Feb 2026

Immunosuppressant treatment reduces cocaine-induced behavioral sensitization in mice

in Neuropharmacology

Gabriella Luciana de Oliveira
Maria Carolina Machado da Silva
Giovanni Freitas Gomes
Roberta dos Santos Ribeiro
Gabriela Reis Cussat
Rúbia Aparecida Fernandes
Jorge Lucas Nascimento Souza
Heliana de Barros Fernandes
Aline Silva de Miranda
Victor Rodrigues Santos

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1757023

597 views

Original Research

Published on 10 Feb 2026

Metabolomic analysis of plasma and brain tissues in fentanyl-induced conditioned place preference mice

in Neuropharmacology

Kaili Du
Xiaoyu Ning
Yongze Han
Xiaoyu Jiang
Zhuoyi Wang
Tao Wang
Hongliang Su
Ting Liu
Bin Cong
Caixia Cheng

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1759491

432 views

Original Research

Accepted on 09 Feb 2026

Adenosine A2A Receptors Regulate D2-type Medium Spiny Neurons in the Nucleus Accumbens to Mediate Pain and Depression Comorbidity

in Neuropharmacology

Dongyu Zhou
Xiaona Yang
Lingzhen Song
Mengyu Wu
Hongxing Zhang
Jun-li Cao
Su Min

Frontiers in Pharmacology

Original Research

Accepted on 06 Feb 2026

Intranasal Delivery of the NMDA Receptor Antagonist MK-801 Attenuates Ultra-Acute Excitotoxic Neurochemical Responses After Concussion in Rats: Comparative Pharmacological Evaluation Against Ketamine

in Neuropharmacology

Ian Masse
Luc Moquin
Caroline Bouchard
Laurianne Legroux
Alain Gratton
Louis De Beaumont

Frontiers in Pharmacology

184 views

Clinical Trial

Accepted on 06 Feb 2026

Serum levels of S100B in patients with chronic schizophrenia during treatment augmentation with sarcosine: results of the double-blind, randomized, placebo-controlled PULSAR study

in Neuropharmacology

Agnieszka Pawlak
Adam Wysokinski
Dominik Strzelecki

Frontiers in Pharmacology

129 views

Review

Accepted on 04 Feb 2026

Selective phosphoinositide 3-kinase inhibitors and implication in diabetic retinopathy as pharmacological tools

in Neuropharmacology

Carmela Bonaccorso
Francesca Lazzara
Isabel La Rosa
Cristina Munzone
Alessandro Grasso
Chiara Bianca Maria Platania
Claudio Bucolo

Frontiers in Pharmacology

206 views

Original Research

Published on 03 Feb 2026

Beyond antipsychotic efficacy and toward an individualized therapeutic strategy: analysis of the systemic, metabolic, and inflammatory effects of olanzapine, haloperidol, and their combination in schizophrenic patients

in Neuropharmacology

Nayef Samah Alharbi
Noha Alaa Hamdy
Esam M. Aboubakr
Mansour Alharbi
Mostafa A. Ali
Ghaleb Alharbi
Ahmed Ibrahim ElMallah

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1727959

558 views

Review

Published on 02 Feb 2026

Advances in pharmacokinetic-pharmacodynamic modeling for anesthesia, 1987–2024: a review

in Neuropharmacology

Yara Tulbah
Ibrahim Aljamaan

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1741851

745 views

Original Research

Accepted on 30 Jan 2026

Rescue of cognitive and negative-like symptoms by chronic aripiprazole treatment in a 3-hit mouse model of neurodevelopmental disorder

in Neuropharmacology

Imane Mouffok
Noa Roudaut
Cécile Chofflet
Thomas Freret
Michel Boulouard
Valentine Bouet

Frontiers in Pharmacology

414 views

Review

Published on 29 Jan 2026

From venom peptides to neurotherapeutics: BmK defensins and short-chain peptides as modulators of ion channels

in Neuropharmacology

Yin Dong
Jiajun Wang
Yudan Zhu
Lu Zhao
Yunqing Zeng
Lele Tang
Qian Xiao
Jiwei Cheng
Chao Wang
Jie Tao

Frontiers in Pharmacology

doi 10.3389/fphar.2026.1754290

560 views

2,654 articles

articles

Peripheral blood RNA-seq analysis in bipolar and schizophrenia spectrum disorders: modest influence of antipsychotic treatment

Nervonic acid confers neuroprotection in a zebrafish model of diabetic neuropathy by promoting myelin repair and metabolic modulation

Disruption of estrogen signaling by developmental exposure to BPA and TBT causes long term functional deficits in zebrafish retina

Comparative pharmacovigilance of non-benzodiazepine receptor agonists versus dual orexin receptor antagonists for insomnia in older adults

Antidepressant-like effects of Rg1 by Mycn: promotion of neurogenesis in the hippocampus

Editorial: Model organisms in neuropharmacology 2024

Dimethyl fumarate and mitochondrial physiology: implications for neurological disorders

Parabrachial calcitonin gene-related peptide neurons sex-specifically modulate behavior in anxiety assays during alcohol withdrawal

Bridging the Translational Gap in Systems Neuroscience: From 1 Circuit Mechanisms to Clinical Therapeutics

Review of Clinical Advances in the Procedural Sedation Application of Remimazolam

Trazodone effectiveness in depression (TED): a comparative evaluation of effect sizes trazodone extended release and SSRIs in the treatment of major depressive disorder

From dopamine to muscarine: xanomeline-trospium (KarXT) as a novel direction in the psychopharmacotherapy of schizophrenia

Correction: Advances in pharmacokinetic-pharmacodynamic modeling for anesthesia, 1987–2024: a review

Review of neuroprotective potential of natural products against hypoxia-induced neuronal injury

Immunosuppressant treatment reduces cocaine-induced behavioral sensitization in mice

Metabolomic analysis of plasma and brain tissues in fentanyl-induced conditioned place preference mice

Adenosine A2A Receptors Regulate D2-type Medium Spiny Neurons in the Nucleus Accumbens to Mediate Pain and Depression Comorbidity

Intranasal Delivery of the NMDA Receptor Antagonist MK-801 Attenuates Ultra-Acute Excitotoxic Neurochemical Responses After Concussion in Rats: Comparative Pharmacological Evaluation Against Ketamine

Serum levels of S100B in patients with chronic schizophrenia during treatment augmentation with sarcosine: results of the double-blind, randomized, placebo-controlled PULSAR study

Selective phosphoinositide 3-kinase inhibitors and implication in diabetic retinopathy as pharmacological tools

Beyond antipsychotic efficacy and toward an individualized therapeutic strategy: analysis of the systemic, metabolic, and inflammatory effects of olanzapine, haloperidol, and their combination in schizophrenic patients

Advances in pharmacokinetic-pharmacodynamic modeling for anesthesia, 1987–2024: a review

Rescue of cognitive and negative-like symptoms by chronic aripiprazole treatment in a 3-hit mouse model of neurodevelopmental disorder

From venom peptides to neurotherapeutics: BmK defensins and short-chain peptides as modulators of ion channels