Frontiers in Pharmacology | Neuropharmacology

Systematic Review

Published on 25 Apr 2025

Effectiveness and safety of single anti-seizure medication as adjunctive therapy for drug-resistant focal epilepsy based on network meta-analysis

in Neuropharmacology

Nian-Jia Deng
Xin-Yi Li
Zhi-Xin Zhang
Chen-Yang Xian-Yu
Yu-Ting Tao
Yu-Tong Ma
Hui-Jun Li
Teng-Yu Gao
Xin Liu
Jie Luo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1500475

6,291 views
3 citations

Original Research

Published on 25 Apr 2025

Suicidal thoughts and behaviors associated with fluoroquinolone antibiotics: a real-world pharmacovigilance analysis

in Neuropharmacology

Lijuan Yang
Congqin Chen
Lingqing Ding
Tingting Lu
Xiwen Li
Jie Xiao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1556159

3,664 views

Mini Review

Published on 25 Apr 2025

Trace amine-associated receptors as potential targets for the treatment of anxiety and depression

in Neuropharmacology

Zelong Li
Luoting Wan
Jing Dong
Jinquan Li
Jianfeng Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1598048

3,100 views
2 citations

Original Research

Published on 25 Apr 2025

In vitro and in-vivo exploration of physostigmine analogues to understand the mechanistic crosstalk between Klotho and targets for epilepsy

in Neuropharmacology

Mansi Dahalia
Haya Majid
Mohd Junaid Khan
Akshat Rathi
Mohd Ashif Khan
Imran Ahmd Khan
Mohammed Samim
Sayeed Ur Rehman
Md Salik Noorani
Divya Vohora

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1580943

3,285 views
3 citations

Original Research

Published on 25 Apr 2025

Edaravone dexborneol protected neurological function by targeting NRF2/ARE and NF-κB/AIM2 pathways in cerebral ischemia/reperfusion injury

in Neuropharmacology

Hui Zhang
Can Zhu
Xingyu Zhou
Laifa Wang
Ling Deng
Binsheng He
Jianming Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1581320

4,538 views
15 citations

Original Research

Published on 24 Apr 2025

Multi-target neuroprotection by dl-PHPB in APP/PS1 mice: a proteomic analysis

in Neuropharmacology

Yingni Sun
Guoliang Bai
Kangmin Yang
Yong Feng
Hongmei Sun
Li Xian
Hongwei Gao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1554168

1,887 views
1 citation

Original Research

Published on 24 Apr 2025

Exploring the diagnostic potential of IL1R1 in depression and its association with lipid metabolism

in Neuropharmacology

Yao Gao
Xiao-Na Song
Nan Zhang
Huang-Hui Liu
Jian-Zhen Hu
Xin-Zhe Du
Guo-Hua Song
Sha Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1519287

2,774 views

Systematic Review

Published on 24 Apr 2025

Tailoring dual antiplatelet therapy for stroke prevention: a meta-analysis of timing, duration, regimen, and stroke subtypes

in Neuropharmacology

Naif M. Alhawiti
Sherouk Fouda
Naser D. Alotaibi
Hassan A. Madkhali
Fahad K. Alsharef
Jamal M. Alhawiti
Ashraf El-Metwally

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1516402

5,032 views
1 citation

Original Research

Published on 23 Apr 2025

Lateral habenula astroglia modulate the potentiating antidepressant-like effects of bright light stimulation in intractable depression

in Neuropharmacology

Sarah Delcourte
Amel Bouloufa
Renaud Rovera
Elie Brunet
Hiep D. Le
April E. Williams
Satchidananda Panda
Rihab Azmani
Olivier Raineteau
Ouria Dkhissi-Benyahya

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1592909

2,549 views
1 citation

Original Research

Published on 23 Apr 2025

Plasticity of ventral tegmental area disturbance during abstinence after repeated amphetamine exposure: restoration by selective activation of group II metabotropic glutamate receptors

in Neuropharmacology

Ornella Valenti
Katarzyna Anna Rekawek
Sophie Wieser
Hilal Bulut
Petra Scholze
Stefan Boehm

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1534101

1,795 views

Review

Published on 23 Apr 2025

Efficacy, safety, and tolerability of soticlestat (TAK-935) as adjunctive therapy in pediatric patients with dravet syndrome and Lennox–Gastaut syndrome: a meta-analysis of 3 randomized controlled trials

in Neuropharmacology

Zhang Lanlan
Jiang Nana
Wang Chengzhong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1586098

2,824 views
1 citation

Original Research

Published on 22 Apr 2025

GluN2B influences the progression of status epilepticus by modulating calcium ion homeostasis through its interaction with CaMKIIα

in Neuropharmacology

Lin Zhang
Youshi Meng
Chaoning Liu
Lei Wei
Yuling Lu
Shouhuan Zheng
Donghua Zou
Yuan Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1550879

2,321 views

Systematic Review

Published on 22 Apr 2025

Curcumin as a potential therapeutic agent for Parkinson’s disease: a systematic review

in Neuropharmacology

Yu-Hsien Chang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1593191

5,770 views
3 citations

Review

Published on 16 Apr 2025

Ginsenoside Rg1 in Parkinson’s disease: from basic research to clinical applications

in Neuropharmacology

Qianyan Wang
Lei Wei
Guanghui Chen
Qiang Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1490480

2,891 views

Systematic Review

Published on 16 Apr 2025

Re-evaluation of the efficacy and safety of anti-Aβ monoclonal antibodies (lecanemab/donanemab) in the treatment of early Alzheimer’s disease

in Neuropharmacology

Haoyang Wang
Junying Pan
Mingming Zhang
Zengde Tan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1599048

9,663 views
5 citations

Original Research

Published on 16 Apr 2025

Significant hindlimb static weight-bearing asymmetry persists for 40-weeks in a longitudinal study in two widely used rat models of surgically induced osteoarthritis knee pain

in Neuropharmacology

A. Kuo
A. Raboczyj
J. R. Nicholson
L. Corradini
M. T. Smith

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1560265

1,499 views
1 citation

Review

Published on 14 Apr 2025

Integrative approaches to depression in end-stage renal disease: insights into mechanisms, impacts, and pharmacological strategies

in Neuropharmacology

Cheng Yuan
Fengpei Chang
Hongfu Zhai
Jiayin Du
Danqin Lu
Haoli Ma
Xiaoyan Wu
Ping Gao
Lihua Ni

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1559038

4,083 views
2 citations

Editorial

Published on 14 Apr 2025

Editorial: Exploring the key targets and compounds that manipulate brain neurocircuits against mental disorders and psychiatric volume II

in Neuropharmacology

Weijie Xie
Yuan Li
Song Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1601881

1,380 views
1 citation

Systematic Review

Published on 11 Apr 2025

Research trends on neutrophil extracellular traps in ischemic stroke: a scientific metrology study

in Neuropharmacology

Yaji Xu
Xingyu Gong
Yilin Wang
Xinyu Liu
Haomou Pu
Hongjie Jiang
Xiaoping Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1537566

4,751 views
2 citations

Original Research

Published on 11 Apr 2025

Social hierarchy modulates drug reinforcement and protein phosphorylation in the nucleus accumbens

in Neuropharmacology

Liang Xu
Ruiyi Zhou
Jiafeng Zhong
Yina Huang
Yingjie Zhu
Wei Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1537131

2,202 views

Original Research

Published on 10 Apr 2025

Contextual and experiential aspects of the psychedelic experience predicting improvement in subjective wellbeing: results from a Norwegian internet convenience sample

in Neuropharmacology

Paula Aarseth Tunstad
Tor-Morten Kvam
Malin V. Uthaug
Lowan H. Stewart
Kristoffer A. A. Andersen
Cato Grønnerød

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1556299

3,128 views
2 citations

Original Research

Published on 10 Apr 2025

Tauroursodeoxycholic acid regulates macrophage/monocyte distribution and improves spinal microenvironment to promote nerve regeneration through inhibiting NF-κB signaling pathway in spinal cord injury

in Neuropharmacology

Yonghui Hou
Yage Zhang
Lin Ma
Dan Luo
Wanshun Wang
Shunmei E.
Chengxi Huang
Yu Hou
Shudong Chen
Jiheng Zhan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1554945

2,465 views
1 citation

Review

Published on 09 Apr 2025

Role of Achyranthes aspera in neurodegenerative diseases: current evidence and future directions

in Neuropharmacology

Huaiqing Luo
Siwen Wei
Shujun Fu
Li Han

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1511011

2,693 views
7 citations

Case Report

Published on 09 Apr 2025

Case Report: Neurofilament light chain in the follow up of progressive multifocal leukoencephalopathy in a patient with multiple sclerosis treated with ocrelizumab

in Neuropharmacology

Raquel Piñar-Morales
Raquel Calle-Calle
Maria Carrasco-Garcia
Cristina Davila-Arias
Luisa Maria Villar-Guimerans
Francisco J. Barrero Hernandez

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1571699

1,916 views

2,620 articles

articles

Effectiveness and safety of single anti-seizure medication as adjunctive therapy for drug-resistant focal epilepsy based on network meta-analysis

Suicidal thoughts and behaviors associated with fluoroquinolone antibiotics: a real-world pharmacovigilance analysis

Trace amine-associated receptors as potential targets for the treatment of anxiety and depression

In vitro and in-vivo exploration of physostigmine analogues to understand the mechanistic crosstalk between Klotho and targets for epilepsy

Edaravone dexborneol protected neurological function by targeting NRF2/ARE and NF-κB/AIM2 pathways in cerebral ischemia/reperfusion injury

Multi-target neuroprotection by dl-PHPB in APP/PS1 mice: a proteomic analysis

Exploring the diagnostic potential of IL1R1 in depression and its association with lipid metabolism

Tailoring dual antiplatelet therapy for stroke prevention: a meta-analysis of timing, duration, regimen, and stroke subtypes

Lateral habenula astroglia modulate the potentiating antidepressant-like effects of bright light stimulation in intractable depression

Plasticity of ventral tegmental area disturbance during abstinence after repeated amphetamine exposure: restoration by selective activation of group II metabotropic glutamate receptors

Efficacy, safety, and tolerability of soticlestat (TAK-935) as adjunctive therapy in pediatric patients with dravet syndrome and Lennox–Gastaut syndrome: a meta-analysis of 3 randomized controlled trials

GluN2B influences the progression of status epilepticus by modulating calcium ion homeostasis through its interaction with CaMKIIα

Curcumin as a potential therapeutic agent for Parkinson’s disease: a systematic review

Ginsenoside Rg1 in Parkinson’s disease: from basic research to clinical applications

Re-evaluation of the efficacy and safety of anti-Aβ monoclonal antibodies (lecanemab/donanemab) in the treatment of early Alzheimer’s disease

Significant hindlimb static weight-bearing asymmetry persists for 40-weeks in a longitudinal study in two widely used rat models of surgically induced osteoarthritis knee pain

Integrative approaches to depression in end-stage renal disease: insights into mechanisms, impacts, and pharmacological strategies

Editorial: Exploring the key targets and compounds that manipulate brain neurocircuits against mental disorders and psychiatric volume II

Research trends on neutrophil extracellular traps in ischemic stroke: a scientific metrology study

Social hierarchy modulates drug reinforcement and protein phosphorylation in the nucleus accumbens

Contextual and experiential aspects of the psychedelic experience predicting improvement in subjective wellbeing: results from a Norwegian internet convenience sample

Tauroursodeoxycholic acid regulates macrophage/monocyte distribution and improves spinal microenvironment to promote nerve regeneration through inhibiting NF-κB signaling pathway in spinal cord injury

Role of Achyranthes aspera in neurodegenerative diseases: current evidence and future directions

Case Report: Neurofilament light chain in the follow up of progressive multifocal leukoencephalopathy in a patient with multiple sclerosis treated with ocrelizumab