Frontiers in Pharmacology | Neuropharmacology

Review

Published on 09 Apr 2025

The roles of extracellular vesicles in mental disorders: information carriers, biomarkers, therapeutic agents

in Neuropharmacology

Longkun Wang
Ruixue Liu
Ying Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1591469

2,167 views

Original Research

Published on 09 Apr 2025

Interpreting the clinical significance of multiple large-scale mitochondrial DNA deletions (MLSMD) in skeletal muscle tissue in the diagnostic evaluation of primary mitochondrial disease

in Neuropharmacology

Jing Wang
James T. Peterson
Joaquim Diego D. Santos
Ada J. S. Chan
Maria Alejandra Diaz-Miranda
Imon Rahaman
Jean Flickinger
Amy Goldstein
Emily Bogush
Elizabeth M. McCormick

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1507493

3,059 views

Original Research

Published on 08 Apr 2025

Brosimine B and the biphasic dose-response: insights into hormesis and retinal neuroprotection

in Neuropharmacology

Susanne Suely Santos Fonseca
Natacha M. S. Port’s
Gisele Priscila Soares Aguiar
Eliã P. Botelho
Nádia M. G. Couto
Wandson Braamcamp Souza Pinheiro
André Salim Khayat
Elizabeth S. Yamada
Edmar T. Costa
Chubert Bernardo C. Sena

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1558726

2,251 views
4 citations

Original Research

Published on 08 Apr 2025

Computational drug repurposing in Parkinson’s disease: Omaveloxolone and cyproheptadine as promising therapeutic candidates

in Neuropharmacology

Xin Guo
Jie Wang
Hongyang Fan
Wanying Tao
Zijing Ren
Xingyue Li
Suyu Liu
Peiyang Zhou
Yingzhu Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1539032

3,976 views
2 citations

Original Research

Published on 08 Apr 2025

Protective effects of 4-HBd on blood–brain barrier integrity in MCAO/R model rats based on brain pharmacokinetic characteristics

in Neuropharmacology

Jin Feng
Qian Yang
Ming Chen
Yan Wang
Dan Luo
Dongxiong Hu
Jianjun Cheng
Xuelan Song
Xiaonan Zhou
Qingting Meng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1528839

2,555 views
1 citation

Editorial

Published on 08 Apr 2025

Editorial: Neuropharmacological intervention for severe mental illness and suicide prevention

in Neuropharmacology

Ewa Litwa
Stefano Comai
Agnieszka Zelek-Molik

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1599083

1,486 views

Original Research

Published on 07 Apr 2025

Global research trends in biomarkers, therapeutic targets, and drugs for amyotrophic lateral sclerosis: a bibliometric and visualization analysis

in Neuropharmacology

Na Guo
Weicheng Huang
Jianliang Huang
Ying Liu
Kai Zhu
Wei Gao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1588968

5,008 views
3 citations

Systematic Review

Published on 07 Apr 2025

Neuroprotective effect and possible mechanism of edaravone in rat models of spinal cord injury: a systematic review and network meta-analysis

in Neuropharmacology

Long-yun Zhou
Xiao-bo Wang
Xu-qing Chen
Ran Li
Bin-bin Yu
Meng-xiao Pan
Lu Fang
Jian Li
Xue-jun Cui
Min Yao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1538879

2,656 views

Review

Published on 03 Apr 2025

Engineered nanoparticles for the treatment of Alzheimer’s disease

in Neuropharmacology

Jia Jia
Shuang Zhao
Jinghan Zhao
Yun Gao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1510798

4,588 views
4 citations

Review

Published on 03 Apr 2025

Natural products protect against spinal cord injury by inhibiting ferroptosis: a literature review

in Neuropharmacology

Wei She
Junxiao Su
Wenji Ma
Guohai Ma
Jianfu Li
Hui Zhang
Cheng Qiu
Xingyong Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1557133

4,871 views
4 citations

Review

Published on 02 Apr 2025

Global research frontiers and thematic trends in opioid-free anesthesia over the past 20 years: a bibliometric analysis

in Neuropharmacology

Junchen He
Rong Huang
Yingzhu Liu
Ying Chen
Min Zhong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1562765

4,733 views
2 citations

Original Research

Published on 02 Apr 2025

A real-world disproportionality analysis of FDA adverse event reporting system (FAERS) events for lecanemab

in Neuropharmacology

Linlin Yan
Linhai Zhang
Zucai Xu
Zhong Luo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1559447

6,209 views
2 citations

Original Research

Published on 01 Apr 2025

Increase of Brivaracetam serum concentration with introduction of Cenobamate

in Neuropharmacology

Lena Bender
Martin Hirsch
Andreas Schulze-Bonhage

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1571376

2,748 views
2 citations

Original Research

Published on 01 Apr 2025

A novel antidepressant mechanism of baicalin: enhancing KIF5A-mediated axoplasmic transport and vesicular trafficking in glutamatergic neurons

in Neuropharmacology

Shuaifei Lu
Jiduo Shen
Xiaohui Jin
Changjing Zhang
Baoying Wang
Xianghua Liu
Ming Bai
Erping Xu
Xiangli Yan
Yucheng Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1577676

2,954 views

Original Research

Published on 01 Apr 2025

A real-world pharmacovigilance study of adverse drug reactions associated with lecanemab and aducanumab based on WHO-VigiAccess and FAERS databases

in Neuropharmacology

Haoxiang Hu
Yunhan Zhao
Jiesheng Mao
Jianghai He
Yihan Zhang
Hongyu Ye
Xiaokai Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1561020

5,773 views
1 citation

Correction

Published on 31 Mar 2025

Corrigendum: Riluzole attenuates acute neural injury and reactive gliosis, hippocampal-dependent cognitive impairments and spontaneous recurrent generalized seizures in a rat model of temporal lobe epilepsy

in Neuropharmacology

Thomas Kyllo
Dominic Allocco
Laine Vande Hei
Heike Wulff
Jeffrey D. Erickson

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1592653

1,227 views

Original Research

Published on 31 Mar 2025

BAM8-22 targets spinal MrgC receptors to modulate UPRmt activity in the mechanism of bone cancer pain

in Neuropharmacology

Mingming Xie
Dan Li
Haohao Zeng
Yulin Huang
Rui Xu
Zhen Wang
Jiacheng Yu
Yu’e Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1575733

2,620 views

Systematic Review

Published on 28 Mar 2025

Effect and safety of perioperative ketamine/esketamine administration on postoperative pain and depression after breast cancer surgery: a systematic review and meta-analysis

in Neuropharmacology

Xinyi Sun
Chengwei Li
Lin Xu
Xiaojie Lin
Zheng Zhang
Chunlong Lin
Jianjun Li
Penghui Wei

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1532524

4,618 views
3 citations

Systematic Review

Published on 27 Mar 2025

Effects of natural extracts in cognitive function of healthy adults: a systematic review and network meta-analysis

in Neuropharmacology

Zhi-yuan Wang
Ya-lu Deng
Ting-yuan Zhou
Yi Liu
Yu Cao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1573034

14,202 views
2 citations

Review

Published on 26 Mar 2025

Exosomes: an innovative therapeutic target for cerebral ischemia-reperfusion injury

in Neuropharmacology

Yuan Yang
Yushan Duan
Jinxi Yue
Yue Yin
Yiming Ma
Xiaohong Wan
Jianlin Shao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1552500

4,967 views
4 citations

Review

Published on 26 Mar 2025

The role and therapeutic potential of mitophagy in major depressive disorder

in Neuropharmacology

Xin-Nuan Shi
Chen-Yue Liu
Lin Li
Ming-Li Yao
Zhen Zhong
You-Ming Jiang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1564276

2,135 views
1 citation

Systematic Review

Published on 26 Mar 2025

Ticagrelor or dipyridamole plus aspirin may be a promising antiplatelet therapy in patients with minor stroke or transient ischemic attack: a bayesian network meta-analysis

in Neuropharmacology

Shiran Qin
Si Gao
Dandan Xu
Li Zhang
Yanmei Luo
Sitong Guo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1561564

3,266 views

Original Research

Published on 26 Mar 2025

The astrocytic sigma-1 receptor constitutes in the fast antidepressant action of hypidone hydrochloride (YL-0919) in rodents

in Neuropharmacology

Jin-Feng Li
Hai-Xia Chang
Jia-Ning Zhao
Jin-Hao Bao
Wei Dai
Yun-Feng Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1564851

2,382 views
1 citation

Original Research

Published on 26 Mar 2025

Neuroprotective effects of arctigenin on cerebral ischemia-reperfusion injury in rats via the EPO/EPOR-JAK2-STAT5 signaling pathway

in Neuropharmacology

Shanshan Xu
Yuting Chen
Lingling Zhang
Wei Lu
Xu Chen
Ting Wang
Wenjie Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1503971

1,742 views