Frontiers in Pharmacology | Neuropharmacology

Original Research

Accepted on 17 Feb 2025

α-Bisabolol Alleviates Doxorubicin-Induced Cognitive Dysfunction in Rats Via Enhancing the Hippocampal BDNF/TrKB Signaling and Inhibiting Neuroinflammation

in Neuropharmacology

Sara Taha Elazab
Walter H Hsu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1549009

Review

Published on 17 Feb 2025

Psychological repercussions of PM air pollution in human aging: a comprehensive review of urban and rural environments

in Neuropharmacology

Laura O. Gallardo
Montserrat Aiger Vallés
Blanca Cativiela-Campos
Laura Domingo-Valero
Ángel Barrasa
Matilde Alique
Caridad López-Granero

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1517090

315 views

Review

Published on 17 Feb 2025

Neurotoxicity mechanisms and clinical implications of six common recreational drugs

in Neuropharmacology

Jing Wang
Yulei Hao
Di Ma
Liangshu Feng
Feng Yang
Pingxu An
Xingqi Su
Jiachun Feng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1526270

214 views

Editorial

Accepted on 14 Feb 2025

Editorial: Novel Therapeutic Target and Drug Discovery for Neurological Diseases, Volume II

in Neuropharmacology

Kaiyue Zhao
Zixuan Li
Ting Sun
Qingshan Liu
Yong Cheng
George Barreto
Zhuorong Li
Rui Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1566950

286 views

Original Research

Published on 14 Feb 2025

Methamphetamine self-administration causes neuronal dysfunction in rat medial prefrontal cortex in a sex-specific and withdrawal time-dependent manner

in Neuropharmacology

Lihua Chen
Tabita Kreko-Pierce
Stefanie L. Cassoday
Lena Al-Harthi
Xiu-Ti Hu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1527795

290 views

Original Research

Published on 14 Feb 2025

The effect of cannabinoid type Ⅱ receptor on the excitability of substantia nigra dopaminergic neurons

in Neuropharmacology

Sha Zhao
Shunfeng Liu
Yongxin Gong
Zegang Ma

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1522210

213 views

Original Research

Published on 13 Feb 2025

Medroxyprogesterone promotes neuronal survival after cerebral ischemic stroke by inhibiting PARthanatos

in Neuropharmacology

Chang-Ling Yue
Yan-Xia Ding
Meng Chen
Yu-Xin Shen
Ao-Meng Hu
Hai Huang
Zhao-Huan Zhang
Ying-Xin Zhou
Xiao-Hui Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1487436

221 views

Original Research

Accepted on 12 Feb 2025

Zingerone Alleviates Inflammatory Pain by Reducing The Intrinsic Excitability of Anterior Cingulate Cortex Neurons in a Mice Model

in Neuropharmacology

Yuanyuan Wang
Lang Dong
Shu Han
Yuehan You
Mingrui Zhang
Bingjing Sun
Hong Ni
Rongjing Ge
Jianhong Liu
Jiandong Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1543594

Original Research

Accepted on 12 Feb 2025

Evaluation of the Neuroprotective Potential of Benzylidene Digoxin 15 (BD-15) against Oxidative Stress in a Neuroinflammation Models Induced by Lipopolysaccharide (LPS) and on neuronal differentiation of hippocampal neural precursor cells

in Neuropharmacology

Gilvânia AR Cordeiro
Jessica Alves Faria
Leticia Pavan Anjos
Israel JP Garcia
Eduarda Paula Ferreira Invernizzi Neves
Gustavo Frazão
Hericles Mesquita Campos
Pâmela Yasmin de Oliveira Ferreira
Paulo César Ghedini
Elisa Mitiko Kawamoto

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1537720

Original Research

Accepted on 12 Feb 2025

Vortioxetine alleviates motor, cognitive and emotional disorders in post-stroke rats by regulating the TLR-2/NF-κB pathway

in Neuropharmacology

Zhengqiang Zou
Ziqiang Dong
Zhihui Dong
Lili Xu
Lin Li
Rongjuan Wang
Xiaoyan Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1555079

Original Research

Accepted on 11 Feb 2025

Randomized crossover clinical studies to assess abuse liability and nicotine pharmacokinetics of Velo oral nicotine pouches

in Neuropharmacology

Milly Kanobe
Christie Powell
Patrudu Makena
Sarah Baxter
Melissa Tapia
John Darnell
Kristen Prevette
Gwyn Gibson
Sarah Ayoku
Leanne Campbell

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1547073

127 views

Original Research

Accepted on 10 Feb 2025

Marked differences in the effects of levetiracetam and its analogue brivaracetam on microglial, astrocytic-and neuronal density in the rat model of kainic acid-induced temporal lobe epilepsy

in Neuropharmacology

Krisztina Kelemen
Máté Sárosi
Ágnes Csüdör
Károly Orbán-Kis
Hanga Kelemen
László Bába
Zsolt Gall
Eszter Horváth
István Katona
Tibor Szilágyi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1553545

116 views

Editorial

Published on 10 Feb 2025

Editorial: The mechanistic investigation and emerging therapies for Friedreich’s ataxia

in Neuropharmacology

Yina Dong
Vijayendran Chandran
Elisabetta Soragni
David R. Lynch

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1560808

418 views

Systematic Review

Accepted on 06 Feb 2025

Clinical implications of fracture severity risk with pioglitazone: A systematic review and meta-analysis of clinical randomized trials

in Neuropharmacology

Hala Azhari
Jesse Dawson

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1357309

Review

Accepted on 05 Feb 2025

World No-Tobacco: Effects of Second-Hand Smoke (SHS) and vapors on the Developing and Adult Brain

in Neuropharmacology

Jacob Raber
Glen Kisby

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1466332

Original Research

Published on 04 Feb 2025

Impact of fluoxetine exposure on Lymnaea stagnalis and its developing eggs: integrating untargeted lipidomics, targeted metabolomics, and classical risk assessment

in Neuropharmacology

Diana Ilyaskina
Yumi Nakadera
Marja H. Lamoree
Joris M. Koene
Pim E. G. Leonards

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1536438

431 views

Navigation group

Articles

α-Bisabolol Alleviates Doxorubicin-Induced Cognitive Dysfunction in Rats Via Enhancing the Hippocampal BDNF/TrKB Signaling and Inhibiting Neuroinflammation

Psychological repercussions of PM air pollution in human aging: a comprehensive review of urban and rural environments

Neurotoxicity mechanisms and clinical implications of six common recreational drugs

Editorial: Novel Therapeutic Target and Drug Discovery for Neurological Diseases, Volume II

Methamphetamine self-administration causes neuronal dysfunction in rat medial prefrontal cortex in a sex-specific and withdrawal time-dependent manner

The effect of cannabinoid type Ⅱ receptor on the excitability of substantia nigra dopaminergic neurons

Medroxyprogesterone promotes neuronal survival after cerebral ischemic stroke by inhibiting PARthanatos

Zingerone Alleviates Inflammatory Pain by Reducing The Intrinsic Excitability of Anterior Cingulate Cortex Neurons in a Mice Model

Evaluation of the Neuroprotective Potential of Benzylidene Digoxin 15 (BD-15) against Oxidative Stress in a Neuroinflammation Models Induced by Lipopolysaccharide (LPS) and on neuronal differentiation of hippocampal neural precursor cells

Vortioxetine alleviates motor, cognitive and emotional disorders in post-stroke rats by regulating the TLR-2/NF-κB pathway

Randomized crossover clinical studies to assess abuse liability and nicotine pharmacokinetics of Velo oral nicotine pouches

Marked differences in the effects of levetiracetam and its analogue brivaracetam on microglial, astrocytic-and neuronal density in the rat model of kainic acid-induced temporal lobe epilepsy

Editorial: The mechanistic investigation and emerging therapies for Friedreich’s ataxia

Clinical implications of fracture severity risk with pioglitazone: A systematic review and meta-analysis of clinical randomized trials

World No-Tobacco: Effects of Second-Hand Smoke (SHS) and vapors on the Developing and Adult Brain

Impact of fluoxetine exposure on Lymnaea stagnalis and its developing eggs: integrating untargeted lipidomics, targeted metabolomics, and classical risk assessment