Frontiers in Pharmacology | Neuropharmacology

Original Research

Published on 09 Jan 2026

Gender and age variations in neuropsychiatric adverse events of cetirizine and levocetirizine: a disproportionality analysis of ICSRs from FAERS and EudraVigilance data

in Neuropharmacology

Tingting Yang
Xiaoxiao Wu
Xueliang Yi
Chunlin Xiang
Yinping Yang
Chen Yang
Xiaoxia Zheng
Yuhong Han
Yiping Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1737359

1,156 views

Systematic Review

Published on 09 Jan 2026

Rodent models of genetic epilepsy and its association with neurocognitive impairment- a systematic review

in Neuropharmacology

Renee Yan Ni Foo
Ian Juin Liang Chiew
Alina Arulsamy
Vanessa Lin Lin Lee

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1659569

889 views

Clinical Trial

Published on 08 Jan 2026

Effectiveness of diterpene ginkgolides meglumine injection after endovascular therapy for cardioembolic stroke: a randomized controlled trial

in Neuropharmacology

Yiping Li
Kun Zhou
Jianan Wei
Xinmin Fu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1707717

826 views

Original Research

Published on 07 Jan 2026

Cerebrolysin, hemorrhagic transformation, and anticoagulation timing after reperfusion therapy in stroke: post hoc secondary analysis of the CEREHETIS trial

in Neuropharmacology

Mikhail N. Kalinin
Dina R. Khasanova

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1725255

1,875 views

Original Research

Published on 06 Jan 2026

Caffeic acid phenethyl ester alleviates 1,2-dichloroethane-induced toxic cerebral edema: central and peripheral mechanisms

in Neuropharmacology

Yue Sun
Bo Yin
Shubei He
Luxin Miao
Jinhan Yang
Yan Wang
Xiaoxia Jin

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1734227

724 views

Original Research

Published on 06 Jan 2026

Sacubitril/valsartan fails to prevent doxorubicin-induced cognitive impairment and hippocampal oxidative, inflammatory, and apoptotic alterations in rats

in Neuropharmacology

Mohrah Muteb Alresheedi
Maha Abdulrahman Aldubayan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1732842

815 views

Systematic Review

Published on 05 Jan 2026

Optimizing phenytoin therapy: a systematic review of clinically relevant food and herb interactions

in Neuropharmacology

Adriana Monserrath Orellana-Paucar
Erick Thomas Mosquera-Lopez
Nancy Michelle Bustamante-Alvarez
María Gabriela Machado-Orellana
Daniela Alejandra Vintimilla-Rojas
John Diego Atiencia-Palacios
Ana Cristina Espinoza-Fajardo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1676685

1,033 views

Systematic Review

Published on 02 Jan 2026

The potential role of GLP-1 receptor agonists in substance use disorders – a systematic review

in Neuropharmacology

K. M. Völker
B. L. H. Prechtl
N. L. Bormann
D. S. Choi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1702448

2,300 views

Review

Published on 02 Jan 2026

System Xc-pathway as a potential regulatory target in neurological disorders

in Neuropharmacology

Ying Chen
Wei Xiao
Chengli Qian
Linshu Huang
Jianghao Lv
Zhuo Wang
Yi Luo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1701320

1,422 views

Original Research

Published on 19 Dec 2025

Environmental enrichment enhances anesthetic actions in rat amygdala hippocampal circuits in vitro

in Neuropharmacology

Kenta Onishi
Rika Sasaki
Koki Hirota
Tomonori Takazawa

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1732630

1,245 views

Original Research

Published on 12 Dec 2025

Real-world disproportionality analysis of sleep disturbances associated with antiseizure medications in epilepsy: a pharmacovigilance study

in Neuropharmacology

Chen Gou
Mengshi Yang
Qingqing Zhao
Yanbing Han

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1740747

2,153 views

Systematic Review

Published on 09 Dec 2025

Is tranexamic acid effective for all traumatic brain injury patients? a severity based systematic review and meta-analysis

in Neuropharmacology

Wentao Bian
Mengxia Qi
Lu Ding
Yixuan Lu
Kangling Yan
Ziqi Wang
Jiancheng Zhang
Ping Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1677936

1,440 views

Correction

Published on 08 Dec 2025

Correction: Neuroprotective role of carvacrol in ischemic brain injury: a systematic review of preclinical evidence and proposed TRPM7 involvement

in Neuropharmacology

Abdulrahman M. Khojah
Hussain Al Dera

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1751557

667 views

Review

Published on 04 Dec 2025

Application of neural stem cells in the treatment of intracerebral hemorrhage: a systematic review

in Neuropharmacology

Ping Song
Zohaib Shafiq
Hongxiang Jiang
Qiang Cai

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1660614

1,579 views

Hypothesis and Theory

Published on 04 Dec 2025

Ibogaine’s potential role in supporting reward system recovery across diagnostic boundaries

in Neuropharmacology

Mark Nicolas

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1744383

2,811 views

Original Research

Published on 03 Dec 2025

T817MA attenuates oxidative stress and ER stress via the HSP70–HSP90 pathway after brain ischemia in vitro and in vivo

in Neuropharmacology

Tao Wang
Ya-Juan Pan
Mei-Mei Zhang
Xuan Wang
Wei Li
Jian-Meng Lv

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1701967

1,124 views

Correction

Published on 03 Dec 2025

Correction: The role of panax notoginseng saponins in cerebrovascular neurological disorders: an overview of mechanisms and functions

in Neuropharmacology

Bin Wang
Xu Gao
Yali Zhang
Yuhua Xiao
Tong Chen
Zhouying Shi
Yue Yuan
Ping Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1750932

754 views

Original Research

Published on 01 Dec 2025

Striatal M4 muscarinic receptors determine the biological rhythm of activity, with a supportive role of M1 muscarinic receptors

in Neuropharmacology

Katerina Janisova
Monika Uhlirova
Sandor Forczek
Jaromir Myslivecek

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1691118

876 views
1 citation

Systematic Review

Published on 01 Dec 2025

Efficacy and safety of esketamine for pain control after cesarean delivery: a systematic review and meta-analysis of randomized controlled trials

in Neuropharmacology

Tingyu Jiang
Rui Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1708221

1,331 views

Original Research

Published on 28 Nov 2025

Kappa-opioid receptor gene (OPRK1) variations associated with opioid abstinence behaviors among chronic heroin users

in Neuropharmacology

Mark K. Greenwald
Catherine Demery
Tabitha E. H. Moses
Margit Burmeister

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1714546

1,107 views

Original Research

Published on 27 Nov 2025

Functional interaction between orexin/dynorphin transmission in the posterior paraventricular nucleus of the thalamus following alcohol dependence: mediation of alcohol-seeking behavior

in Neuropharmacology

Francisco J. Flores-Ramirez
Glenn Pascasio
Rémi Martin-Fardon

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1718540

1,755 views
1 citation

Correction

Published on 26 Nov 2025

Correction: Lack of the Nlrp3 inflammasome improves mice recovery following traumatic brain injury

in Neuropharmacology

Natasha Irrera
Gabriele Pizzino
Margherita Calò
Giovanni Pallio
Federica Mannino
Fausto Famà
Vincenzo Arcoraci
Vincenzo Fodale
Antonio David
Francesca Cosentino

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1733683

570 views

Review

Published on 26 Nov 2025

Bortezomib-induced peripheral neuropathy: from molecular mechanisms to clinical management

in Neuropharmacology

Yuting Yan
Yanqi Song
Quan Zhang
Lingwei Hu
Aidi Wang
Honglei Guo
Zhen Wang
Lin Ma
Baoshan Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1719384

2,014 views

Review

Published on 26 Nov 2025

Signal transduction, dimerization, and therapeutic targeting of Orexin and receptor systems

in Neuropharmacology

Shengnan Zhang
Peixiang Wang
Bingyuan Ji
Yuming Shao
Sen Hou
Jing Chen
Chunmei Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1697406

1,995 views
2 citations

2,654 articles

articles

Gender and age variations in neuropsychiatric adverse events of cetirizine and levocetirizine: a disproportionality analysis of ICSRs from FAERS and EudraVigilance data

Rodent models of genetic epilepsy and its association with neurocognitive impairment- a systematic review

Effectiveness of diterpene ginkgolides meglumine injection after endovascular therapy for cardioembolic stroke: a randomized controlled trial

Cerebrolysin, hemorrhagic transformation, and anticoagulation timing after reperfusion therapy in stroke: post hoc secondary analysis of the CEREHETIS trial

Caffeic acid phenethyl ester alleviates 1,2-dichloroethane-induced toxic cerebral edema: central and peripheral mechanisms

Sacubitril/valsartan fails to prevent doxorubicin-induced cognitive impairment and hippocampal oxidative, inflammatory, and apoptotic alterations in rats

Optimizing phenytoin therapy: a systematic review of clinically relevant food and herb interactions

The potential role of GLP-1 receptor agonists in substance use disorders – a systematic review

System Xc-pathway as a potential regulatory target in neurological disorders

Environmental enrichment enhances anesthetic actions in rat amygdala hippocampal circuits in vitro

Real-world disproportionality analysis of sleep disturbances associated with antiseizure medications in epilepsy: a pharmacovigilance study

Is tranexamic acid effective for all traumatic brain injury patients? a severity based systematic review and meta-analysis

Correction: Neuroprotective role of carvacrol in ischemic brain injury: a systematic review of preclinical evidence and proposed TRPM7 involvement

Application of neural stem cells in the treatment of intracerebral hemorrhage: a systematic review

Ibogaine’s potential role in supporting reward system recovery across diagnostic boundaries

T817MA attenuates oxidative stress and ER stress via the HSP70–HSP90 pathway after brain ischemia in vitro and in vivo

Correction: The role of panax notoginseng saponins in cerebrovascular neurological disorders: an overview of mechanisms and functions

Striatal M4 muscarinic receptors determine the biological rhythm of activity, with a supportive role of M1 muscarinic receptors

Efficacy and safety of esketamine for pain control after cesarean delivery: a systematic review and meta-analysis of randomized controlled trials

Kappa-opioid receptor gene (OPRK1) variations associated with opioid abstinence behaviors among chronic heroin users

Functional interaction between orexin/dynorphin transmission in the posterior paraventricular nucleus of the thalamus following alcohol dependence: mediation of alcohol-seeking behavior

Correction: Lack of the Nlrp3 inflammasome improves mice recovery following traumatic brain injury

Bortezomib-induced peripheral neuropathy: from molecular mechanisms to clinical management

Signal transduction, dimerization, and therapeutic targeting of Orexin and receptor systems