Frontiers in Pharmacology | Neuropharmacology

Original Research

Published on 19 Dec 2024

Progressive iron overload in middle-aged mice impairs olfactory function, triggers lipid oxidation and induces apoptosis

in Neuropharmacology

Lin Deng
Qihui Luo
Yucong Liu
Yao Wang
Zongliang Xiong
Hongping Wang
Lu Zhao
Lanlan Jia
Riyi Shi
Chao Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1506944

675 views

Original Research

Published on 19 Dec 2024

Catalpol promotes hippocampal neurogenesis and synaptogenesis in rats after multiple cerebral infarctions by mitochondrial regulation: involvement of the Shh signaling pathway

in Neuropharmacology

Zishan Huang
Feng Li
Xiaoyu Zheng
Jiarui Zheng
Yilei Dong
Zhao Ding
Huanyu Gou
Mingjiang Yao
Jianxun Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1461279

837 views

Brief Research Report

Published on 18 Dec 2024

Slick potassium channels limit TRPM3-mediated activation of sensory neurons

in Neuropharmacology

Patrick Engel
Fangyuan Zhou
Bang Tam Thi Tran
Achim Schmidtko
Ruirui Lu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1459735

860 views

Systematic Review

Published on 18 Dec 2024

Role of memantine in adult migraine: a systematic review and network meta-analysis to compare memantine with existing migraine preventive medications

in Neuropharmacology

Guanglu Li
Baoquan Qu
Tao Zheng
Shaojie Duan
Lei Liu
Zunjing Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1496621

1,145 views

Clinical Trial

Published on 16 Dec 2024

Determining the effective dose of esketamine combined with propofol for painless hysteroscopy: a prospective dose-finding study

in Neuropharmacology

Zhimin Sheng
Xiang Liu
Kang Lin
Jie Liu
Junqin Mao
Xiaowei Qian

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1419732

507 views

Original Research

Published on 13 Dec 2024

Anesthetic spindles serve as EEG markers of the depth variations in anesthesia induced by multifarious general anesthetics in mouse experiments

in Neuropharmacology

Ying You
Hui Liu
Zhanfei Yang
Yuxuan Chen
Fei Yang
Tian Yu
Yu Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1474923

581 views

Correction

Published on 11 Dec 2024

Corrigendum: Edaravone dexborneol treatment attenuates neuronal apoptosis and improves neurological function by suppressing 4-HNE-associated oxidative stress after subarachnoid hemorrhage

in Neuropharmacology

Qian Chen
Yichen Cai
Xiaoyu Zhu
Jing Wang
Feng Gao
Mingfeng Yang
Leilei Mao
Zongyong Zhang
Baoliang Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1508703

485 views

Original Research

Published on 10 Dec 2024

The fruit fly Drosophila melanogaster as a screening model for antiseizure medications

in Neuropharmacology

Florian P. Fischer
Robin A. Karge
Henner Koch
Aaron Voigt
Yvonne G. Weber
Stefan Wolking

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1489888

1,332 views

Original Research

Published on 06 Dec 2024

Pharmacological inhibition of receptor protein tyrosine phosphatase β/ζ decreases Aβ plaques and neuroinflammation in the hippocampus of APP/PS1 mice

in Neuropharmacology

Teresa Fontán-Baselga
Héctor Cañeque-Rufo
Elisa Rivera-Illades
Esther Gramage
José María Zapico
Beatriz de Pascual-Teresa
María Del Pilar Ramos-Álvarez
Gonzalo Herradón
Marta Vicente-Rodríguez

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1506049

1,078 views

Original Research

Published on 05 Dec 2024

A functional unbalance of TRPM8 and Kv1 channels underlies orofacial cold allodynia induced by peripheral nerve damage

in Neuropharmacology

Ricardo Piña
Gonzalo Ugarte
Camilo Guevara
Richard Pino
Katherine Valdebenito
Sofía Romero
Ana Gómez del Campo
Víctor Hugo Cornejo
María Pertusa
Rodolfo Madrid

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1484387

1,280 views

Original Research

Published on 05 Dec 2024

Integrated bioinformatics and interaction analysis to advance chronotherapies for mental disorders

in Neuropharmacology

Apoorva Bhatnagar
Gupta Raj
Sandip Das
Arpita Kannihali
Eerappa Rajakumara
Greg Murray
Sandipan Ray

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1444342

981 views

Original Research

Published on 04 Dec 2024

Deep brain stimulation combined with morroniside promotes neural plasticity and motor functional recovery after ischemic stroke

in Neuropharmacology

Yanxi Chen
Zhidong Xu
Yifu Ma
Tingting Liu
Xin Tian
Zixin Zhu
Wenrong Zheng
Yufeng Wang
Ruifang Zheng
Jianguo Xing

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1457309

650 views

Original Research

Published on 03 Dec 2024

Prefrontal serotonin depletion delays reversal learning and increases theta synchronization of the infralimbic-prelimbic-orbitofrontal prefrontal cortex circuit

in Neuropharmacology

Yoana Estrada-Reyes
José Miguel Cervantes-Alfaro
Miguel Ángel López-Vázquez
María Esther Olvera-Cortés

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1501896

769 views

Mini Review

Published on 02 Dec 2024

Mitigating neurodegenerative diseases: the protective influence of baicalin and baicalein through neuroinflammation regulation

in Neuropharmacology

Rui Yang
Ranran Wang
Ajing Xu
Jian Zhang
Jing Ma

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1425731

1,188 views

Original Research

Published on 29 Nov 2024

Overexpression of endothelial S1pr2 promotes blood–brain barrier disruption via JNK/c-Jun/MMP-9 pathway after traumatic brain injury in both in vivo and in vitro models

in Neuropharmacology

Hongbo Cheng
Yijiao Men
Yaqing An
Jiegang Yu
Gengshen Zhang
Jiaming Li
Xiaoliang Wang
Guozhu Sun
Yang Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1448570

1,085 views

Review

Published on 27 Nov 2024

Microglia in morphine tolerance: cellular and molecular mechanisms and therapeutic potential

in Neuropharmacology

Xiangning Zhang
Tingting Jin
Haixia Wang
Shuai Han
Yongxin Liang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1499799

790 views

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Articles

Progressive iron overload in middle-aged mice impairs olfactory function, triggers lipid oxidation and induces apoptosis

Catalpol promotes hippocampal neurogenesis and synaptogenesis in rats after multiple cerebral infarctions by mitochondrial regulation: involvement of the Shh signaling pathway

Slick potassium channels limit TRPM3-mediated activation of sensory neurons

Role of memantine in adult migraine: a systematic review and network meta-analysis to compare memantine with existing migraine preventive medications

Determining the effective dose of esketamine combined with propofol for painless hysteroscopy: a prospective dose-finding study

Anesthetic spindles serve as EEG markers of the depth variations in anesthesia induced by multifarious general anesthetics in mouse experiments

Corrigendum: Edaravone dexborneol treatment attenuates neuronal apoptosis and improves neurological function by suppressing 4-HNE-associated oxidative stress after subarachnoid hemorrhage

The fruit fly Drosophila melanogaster as a screening model for antiseizure medications

Pharmacological inhibition of receptor protein tyrosine phosphatase β/ζ decreases Aβ plaques and neuroinflammation in the hippocampus of APP/PS1 mice

A functional unbalance of TRPM8 and Kv1 channels underlies orofacial cold allodynia induced by peripheral nerve damage

Integrated bioinformatics and interaction analysis to advance chronotherapies for mental disorders

Deep brain stimulation combined with morroniside promotes neural plasticity and motor functional recovery after ischemic stroke

Prefrontal serotonin depletion delays reversal learning and increases theta synchronization of the infralimbic-prelimbic-orbitofrontal prefrontal cortex circuit

Mitigating neurodegenerative diseases: the protective influence of baicalin and baicalein through neuroinflammation regulation

Overexpression of endothelial S1pr2 promotes blood–brain barrier disruption via JNK/c-Jun/MMP-9 pathway after traumatic brain injury in both in vivo and in vitro models

Microglia in morphine tolerance: cellular and molecular mechanisms and therapeutic potential