Frontiers in Pharmacology | Neuropharmacology

Original Research

Published on 27 Nov 2024

Role of Rab10 in cocaine-induced behavioral effects is associated with GABAB receptor membrane expression in the nucleus accumbens

in Neuropharmacology

Zhuoxuan Yu
Qiang Fu
Tianyun Qiu
Caidi Yang
Mingfen Lu
Qinghua Peng
Jianhua Yang
Zhenzhen Hu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1496657

614 views

Original Research

Published on 26 Nov 2024

Correlation of the DRD2 gene polymorphism with psychopathology and predictive antimanic responses in patients with bipolar mania

in Neuropharmacology

Hejian Tao
Haiying Jin
Min Xu
Haihan Chen
Fengli Sun
Weidong Jin

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1465356

468 views

Original Research

Published on 26 Nov 2024

Molecular targets and mechanisms of Sijunzi decoction in the treatment of Parkinson’s disease: evidence from network pharmacology, molecular docking, molecular dynamics simulation, and experimental validation

in Neuropharmacology

Yang Jiang
Wanfeng Wu
Le Xie
Yue Zhou
Kailin Yang
Dahua Wu
Wenfeng Xu
Rui Fang
Jinwen Ge

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1487474

1,806 views

Review

Published on 25 Nov 2024

Therapeutic potential and mechanisms of stem cells in major depressive disorder: a comprehensive review

in Neuropharmacology

Jiaqi Li
Yuqian Wang
Yucheng Zhang
Mengran Liu
Xinao Rong
Jinlan Jiang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1476558

878 views
1 citation

Original Research

Published on 22 Nov 2024

Adverse event profile of lorazepam: a real-world pharmacovigilance study using the FDA adverse event reporting system database

in Neuropharmacology

Zhengkang Su
Zhengwei Huang
Xiaoyu Chen
Xi Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1465245

1,237 views

Original Research

Published on 22 Nov 2024

Chrysophanol attenuates cognitive impairment, neuroinflammation, and oxidative stress by TLR4/NFκB-Nrf2/HO-1 and BDNF/VEGF signaling in stress-intensified PTZ induced epilepsy in mice

in Neuropharmacology

Jehan Zeb Khan
Syeda Rida Zainab
Mujeeb Ur Rehman
Muhammad Abid
Fawad Ali Shah
Najeeb Ur Rehman
Muhammad Khalid Tipu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1446304

1,139 views

Review

Published on 22 Nov 2024

Mirogabalin as a novel calcium channel α2δ ligand for the treatment of neuropathic pain: a review of clinical update

in Neuropharmacology

Fei Yang
Yan Wang
Mingjie Zhang
Shengyuan Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1491570

1,825 views

Original Research

Published on 21 Nov 2024

Effect of melatonin on gut microbiome and metabolomics in diabetic cognitive impairment

in Neuropharmacology

Ming Gao
Jie Li
Xu Han
Beiyao Zhang
Jinting Chen
Jiadong Lang
Qiangqiang Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1489834

1,568 views
3 citations

Original Research

Published on 20 Nov 2024

Fisetin exerts neuroprotective effects in vivo and in vitro by inhibiting ferroptosis and oxidative stress after traumatic brain injury

in Neuropharmacology

Haiyi Yang
Ye Hong
Mingjie Gong
Shihong Cai
Zhongwen Yuan
Senling Feng
Qibo Chen
Xixia Liu
Zhengrong Mei

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1480345

1,350 views
1 citation

Original Research

Published on 15 Nov 2024

Tetramethylpyrazine inhibits ferroptosis in spinal cord injury by regulating iron metabolism through the NRF2/ARE pathway

in Neuropharmacology

Jingwei Tao
Jingya Zhou
Hanjie Zhu
Lin Xu
Jizhou Yang
Xiaohong Mu
Xiao Fan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1503064

977 views

Original Research

Published on 14 Nov 2024

Bmal1 haploinsufficiency impairs fear memory and modulates neuroinflammation via the 5-HT2C receptor

in Neuropharmacology

Weifen Li
Shengnan Mou
Tahir Ali
Tianxiang Li
Yan Liu
Shupeng Li
Xiaoming Yu
Zhi-Jian Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1422693

1,132 views

Original Research

Published on 13 Nov 2024

Cannabidiol inhibits transient receptor potential canonical 4 and modulates excitability of pyramidal neurons in mPFC

in Neuropharmacology

Yujun Han
Shuting Wang
Yu Xiang
Liuliu Chang
Xian Wang
Shimin Ren
Fei Guo
Tianyu Li
Zhiqiang Liu
Yang Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1431758

1,284 views

Brief Research Report

Published on 12 Nov 2024

OATP1A2 mediates Aβ1-42 transport and may be a novel target for the treatment of Alzheimer’s disease

in Neuropharmacology

Jinhua Wen
Menghua Zhao
Yuwei Xiao
Sihong Li
Weiqiang Hu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1443789

631 views

Original Research

Published on 12 Nov 2024

Effect of NLRP3 inflammasome induced astrocyte phenotype alteration in morphine tolerance

in Neuropharmacology

Zhenyu Yuan
Boxuan Lu
Meiling Zhang
Yinxiao Lu
Zhihui Wang
Wenhao Zhang
Hao Cheng
Zhifang Wu
Qing Ji

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1434295

801 views

Original Research

Published on 11 Nov 2024

Evaluation of pitolisant, sodium oxybate, solriamfetol, and modafinil for the management of narcolepsy: a retrospective analysis of the FAERS database

in Neuropharmacology

Xiaodan Zhou
Jia Chen
Bangtian Xu
Li Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1415918

2,484 views
1 citation

Systematic Review

Published on 07 Nov 2024

Efficacy analysis of neuroprotective drugs in patients with acute ischemic stroke based on network meta-analysis

in Neuropharmacology

Mei Li
Xianhao Huo
Qing Chang
Xiaozhuo Liu
Jianning Zhang
Zhiqi Mao

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1475021

1,834 views

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Articles

Role of Rab10 in cocaine-induced behavioral effects is associated with GABAB receptor membrane expression in the nucleus accumbens

Correlation of the DRD2 gene polymorphism with psychopathology and predictive antimanic responses in patients with bipolar mania

Molecular targets and mechanisms of Sijunzi decoction in the treatment of Parkinson’s disease: evidence from network pharmacology, molecular docking, molecular dynamics simulation, and experimental validation

Therapeutic potential and mechanisms of stem cells in major depressive disorder: a comprehensive review

Adverse event profile of lorazepam: a real-world pharmacovigilance study using the FDA adverse event reporting system database

Chrysophanol attenuates cognitive impairment, neuroinflammation, and oxidative stress by TLR4/NFκB-Nrf2/HO-1 and BDNF/VEGF signaling in stress-intensified PTZ induced epilepsy in mice

Mirogabalin as a novel calcium channel α2δ ligand for the treatment of neuropathic pain: a review of clinical update

Effect of melatonin on gut microbiome and metabolomics in diabetic cognitive impairment

Fisetin exerts neuroprotective effects in vivo and in vitro by inhibiting ferroptosis and oxidative stress after traumatic brain injury

Tetramethylpyrazine inhibits ferroptosis in spinal cord injury by regulating iron metabolism through the NRF2/ARE pathway

Bmal1 haploinsufficiency impairs fear memory and modulates neuroinflammation via the 5-HT2C receptor

Cannabidiol inhibits transient receptor potential canonical 4 and modulates excitability of pyramidal neurons in mPFC

OATP1A2 mediates Aβ1-42 transport and may be a novel target for the treatment of Alzheimer’s disease

Effect of NLRP3 inflammasome induced astrocyte phenotype alteration in morphine tolerance

Evaluation of pitolisant, sodium oxybate, solriamfetol, and modafinil for the management of narcolepsy: a retrospective analysis of the FAERS database

Efficacy analysis of neuroprotective drugs in patients with acute ischemic stroke based on network meta-analysis