Frontiers in Pharmacology | Neuropharmacology

Original Research

Published on 06 Aug 2025

DMH1-loaded peptide nanomicelles restore myelin and attenuate neuroinflammation in trigeminal neuralgia via CCL5 suppression

in Neuropharmacology

Shuangyin Xia
Xiunan Qin
Yaping Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1590624

3,957 views

Original Research

Published on 05 Aug 2025

Ineffectiveness of tirzepatide in mitigating Doxorubicin-induced oxidative stress and cognitive deficits in a rat model

in Neuropharmacology

Salma A. Alolayan
Ahmad H. Alhowail

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1638527

2,187 views
1 citation

Original Research

Published on 01 Aug 2025

Neurological adverse events associated with antidepressants: a comprehensive 22-year analysis of the FDA adverse event reporting system

in Neuropharmacology

Qian Yu
Jingyang Yao
Enping Li
Mingkai Xia
Ziang Hu
Yun Xiao
Jianliang Huang
Mingsheng Lei

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1644241

4,558 views
3 citations

Review

Published on 01 Aug 2025

Dexmedetomidine and the glymphatic system: a new perspective in managing postoperative cognitive dysfunction

in Neuropharmacology

Sha-Sha Zhang
Fan-Geng Meng
Yuan-Yuan Rong
Yi-Wen Zhang
Hua-Qin Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1648308

4,029 views
3 citations

Original Research

Published on 31 Jul 2025

α-Lipoic acid mitigates age-related macular degeneration via ferroptosis: integrative multi-omics and network pharmacology

in Neuropharmacology

Yaqiong Zhang
Yuanyuan Chen
Chenglin Sun
Fang Li
Yin Shen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1626907

3,403 views
1 citation

Original Research

Published on 30 Jul 2025

Identification of potential drug-induced neuralgia signals through disproportionality analysis of the FAERS database

in Neuropharmacology

Yating An
Ying Zheng
Ziwei Jiang
Meng Meng
Jintuo Yin
Yahui An

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1645114

2,522 views

Original Research

Published on 28 Jul 2025

The SAP130/Mincle axis was involved in sevoflurane-induced neuronal death and microglial activation in juvenile mice

in Neuropharmacology

Zi-Heng Zhou
Xiao-Xiang Chen
Wen Zhang
Bin Shu
Ying Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1647329

1,507 views

Case Report

Published on 25 Jul 2025

Case Report: Successful treatment of spondyloenchondrodysplasia with immune dysregulation using tofacitinib and ruxolitinib: a report of two pediatric cases

in Neuropharmacology

Chengzhu Liu
Zhiwei Xie
Min Wang
Jinhua Chu
Linhai Yang
Kunlong Zhang
Lingling Huang
Songji Tu
Huaju Cai
Zhengyu Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1588003

1,792 views

Original Research

Published on 25 Jul 2025

Assessment of drug-related migraine in a real-world large-scale database

in Neuropharmacology

Fan Wu
Ao Liu
Zhenyuan Jiang
Zhonglin Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1647088

2,484 views

Original Research

Published on 23 Jul 2025

The effect of oral administration of NXP032 equivalent to intraperitoneal administration in an Alzheimer’s disease model

in Neuropharmacology

Jae Min Lee
You Jung Choi
Da-Eun Sung
Tae Hyeok Sim
So Hee Kim
Seung Geun Yeo
Youn-Jung Kim

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1632640

1,711 views

Original Research

Published on 23 Jul 2025

Synergistic effects of combined hypnotic drugs on sleep in mice

in Neuropharmacology

Rui Bai
Chu Wang
Fanghui Wu
Yifeng Yin
Yanli Liu
Yuan Gao
Yunyang Song

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1596813

2,732 views

Original Research

Published on 23 Jul 2025

S-ketamine facilitates motor function recovery after brachial plexus root avulsion and reimplantation in mice

in Neuropharmacology

Ronghua Huang
Bingbiao Lin
Lingtai Yu
Qichen Luo
Hongyan Tian
Chenrui Li
Naili Wei
Shaohui Zhuang
Jian Chen
Yalan Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1630158

2,448 views
1 citation

Review

Published on 23 Jul 2025

Harnessing nanotechnology for stem-cell therapies: revolutionizing neurodegenerative disorder treatments – a state-of-the-art update

in Neuropharmacology

Neevashini Chengebroyen
Anmol Seelan
Kamal Yoonus Thajudeen
Saad Ali Alshehri
Aritra Biswas
Israrahmed Adur
Vino Sundararajan
Sajitha Lulu Sudhakaran
Harpreet Singh

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1630475

4,310 views

Original Research

Published on 22 Jul 2025

Cannabidiol reduces synaptic strength and neuronal firing in layer V pyramidal neurons of the human cortex with drug-resistant epilepsy

in Neuropharmacology

Vladimir A. Martinez-Rojas
Luis A. Márquez
Christopher Martinez-Aguirre
Isabel Sollozo-Dupont
Félix Iván López Preza
Monserrat Fuentes Mejía
Mario Alonso
Luisa Rocha
Emilio J. Galván

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1627465

2,822 views
3 citations

Original Research

Published on 21 Jul 2025

Preclinical pharmacology of alogabat: a novel GABAA-α5 positive allosteric modulator targeting neurodevelopmental disorders with impaired GABAA signaling

in Neuropharmacology

Giuseppe Cecere
Theresa M. Ballard
Frederic Knoflach
Michael Honer
Joerg F. Hipp
Pilar Garces
Thomas Mueggler
Basil Künnecke
Andreas Bruns
Eric P. Prinssen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1626078

4,296 views

Mini Review

Published on 21 Jul 2025

Pharmacogenetics or predictive genetics? APOE testing blurs the lines

in Neuropharmacology

Stefania Zampatti
Cristina Peconi
Juliette Farro
Fabrizio Piras
Clelia Pellicano
Carlo Caltagirone
Emiliano Giardina

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1627239

2,981 views

Opinion

Published on 18 Jul 2025

Several endocannabinoids and amino acids may be biosynthetically converted to catecholamines in vivo

in Neuropharmacology

Paul J. Fitzgerald

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1614460

2,146 views
1 citation

Correction

Published on 18 Jul 2025

Correction: The antipsychotics functional index (AFI) in schizophrenia

in Neuropharmacology

Gabriel-Cristian Marinescu
Petru Iulian Ifteni
Andreea Teodorescu
Radu Georgescu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1662228

854 views

Review

Published on 18 Jul 2025

Genetic implication of GABAB receptors in the etiology of neurological and psychiatric disorders

in Neuropharmacology

Martin Gassmann
Michal Stawarski
Stylianos E. Antonarakis
Bernhard Bettler

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1634128

3,798 views

Review

Published on 16 Jul 2025

Pharmacological mechanisms and potential clinical applications of Dihydromyricetin in neurological disorders

in Neuropharmacology

Yike Zhang
Tingting Zhang
Manli Zhao
Peichun Li
Tao Liu
Jiangbo Xie

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1618623

2,894 views

Review

Published on 16 Jul 2025

Cerebral ischemia-reperfusion injury: mechanisms and promising therapies

in Neuropharmacology

Mingming Yang
Boya Liu
Bingqian Chen
Yuntian Shen
Guangliang Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1613464

9,079 views
9 citations

Original Research

Published on 11 Jul 2025

Ursolic acid ameliorates cerebral ischemia-reperfusion injury by inhibiting NF-κB/NLRP3-mediated microglia pyroptosis and neuroinflammation

in Neuropharmacology

Junbin Liu
Xiaoting Zhang
Jingpei Guo
Yun Zhang
Jinming Fan
Junfeng Liu
Jiawen Chen
Jiawei Jiang
Benshuai Yu
Ke Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1622131

4,179 views
3 citations

Correction

Published on 11 Jul 2025

Correction: Novel multitarget analgesic candidate SZV-1287 demonstrates potential disease-modifying effects in the monoiodoacetate-induced osteoarthritis mouse model

in Neuropharmacology

Ádám István Horváth
Kata Bölcskei
Nikolett Szentes
Éva Borbély
Valéria Tékus
Bálint Botz
Kitti Rusznák
Anett Futácsi
Boldizsár Czéh
Péter Mátyus

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1646562

1,402 views
1 citation

Original Research

Published on 11 Jul 2025

Ramipril and ketogenic diet response in cognitive dysfunction of insulin-resistant rats

in Neuropharmacology

Nancy M. Abdel-Kareem
Shimaa M. Elshazly
May A. Abd El Fattah
Sawsan A. Zaitone
Thanaa A. Elmasry
Asmaa Saleh
Enas A. Abd El-Haleim

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1620139

1,949 views

2,654 articles

articles

DMH1-loaded peptide nanomicelles restore myelin and attenuate neuroinflammation in trigeminal neuralgia via CCL5 suppression

Ineffectiveness of tirzepatide in mitigating Doxorubicin-induced oxidative stress and cognitive deficits in a rat model

Neurological adverse events associated with antidepressants: a comprehensive 22-year analysis of the FDA adverse event reporting system

Dexmedetomidine and the glymphatic system: a new perspective in managing postoperative cognitive dysfunction

α-Lipoic acid mitigates age-related macular degeneration via ferroptosis: integrative multi-omics and network pharmacology

Identification of potential drug-induced neuralgia signals through disproportionality analysis of the FAERS database

The SAP130/Mincle axis was involved in sevoflurane-induced neuronal death and microglial activation in juvenile mice

Case Report: Successful treatment of spondyloenchondrodysplasia with immune dysregulation using tofacitinib and ruxolitinib: a report of two pediatric cases

Assessment of drug-related migraine in a real-world large-scale database

The effect of oral administration of NXP032 equivalent to intraperitoneal administration in an Alzheimer’s disease model

Synergistic effects of combined hypnotic drugs on sleep in mice

S-ketamine facilitates motor function recovery after brachial plexus root avulsion and reimplantation in mice

Harnessing nanotechnology for stem-cell therapies: revolutionizing neurodegenerative disorder treatments – a state-of-the-art update

Cannabidiol reduces synaptic strength and neuronal firing in layer V pyramidal neurons of the human cortex with drug-resistant epilepsy

Preclinical pharmacology of alogabat: a novel GABAA-α5 positive allosteric modulator targeting neurodevelopmental disorders with impaired GABAA signaling

Pharmacogenetics or predictive genetics? APOE testing blurs the lines

Several endocannabinoids and amino acids may be biosynthetically converted to catecholamines in vivo

Correction: The antipsychotics functional index (AFI) in schizophrenia

Genetic implication of GABAB receptors in the etiology of neurological and psychiatric disorders

Pharmacological mechanisms and potential clinical applications of Dihydromyricetin in neurological disorders

Cerebral ischemia-reperfusion injury: mechanisms and promising therapies

Ursolic acid ameliorates cerebral ischemia-reperfusion injury by inhibiting NF-κB/NLRP3-mediated microglia pyroptosis and neuroinflammation

Correction: Novel multitarget analgesic candidate SZV-1287 demonstrates potential disease-modifying effects in the monoiodoacetate-induced osteoarthritis mouse model

Ramipril and ketogenic diet response in cognitive dysfunction of insulin-resistant rats