Frontiers in Pharmacology | Neuropharmacology

Review

Published on 25 Jun 2025

Gut-brain axis in post-traumatic stress disorder: microbial - mediated mechanisms and new therapeutic approaches - A narrative review

in Neuropharmacology

Jiayue Pan
Shuairong Lin
Qiuling Qian
Shanni Fu
Xiaoliu Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1621678

3,895 views
2 citations

Editorial

Published on 25 Jun 2025

Editorial: Innovative therapies against neurodegenerative disorders: from new active molecules to novel drug delivery systems

in Neuropharmacology

Panoraia I. Siafaka
Mehmet Evren Okur
Neslihan Üstündağ Okur

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1640758

1,512 views

Review

Published on 25 Jun 2025

Ketogenic therapy for schizophrenia: evidence, mechanisms, and clinical perspectives

in Neuropharmacology

Cristiano Chaves
Jennifer Fabe
Fabiano A. Gomes
Heather McNeely
Massimo Tusconi
Mauro Giovanni Carta
Serdar M. Dursun
Jaime E. C. Hallak
Elisa Brietzke

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1603722

5,692 views
2 citations

Mini Review

Published on 24 Jun 2025

Research on the effects of GLP-1 receptor agonists in treating cognitive dysfunction and gait disorders in elderly patients with diabetes

in Neuropharmacology

Yang Yang
Lifeng Chen
Yanjun Zhang
Wenqian Fu
Dandan Liu
Tianyu Jiang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1607443

2,713 views
1 citation

Review

Published on 23 Jun 2025

Unveiling the therapeutic potential of natural products in Alzheimer’s disease: insights from in vitro, in vivo, and clinical studies

in Neuropharmacology

Nahida Aktary
Yerim Jeong
Seungji Oh
Yeju Shin
Yoonsoo Sung
Muntajin Rahman
Livia Ramos Santiago
Jinwon Choi
Han Gyeul Song
Fahrul Nurkolis

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1601712

9,162 views
6 citations

Original Research

Published on 20 Jun 2025

Network pharmacology-based prediction and “gut microbiota-inflammation-brain axis” validation of the active ingredients and potential mechanisms of Plantagins Herba for treating diabetes-related cognitive dysfunction

in Neuropharmacology

Zhixuan Huang
Jian Liu
Hui Li
Yangwen Ai
Dongyue Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1601689

2,649 views
1 citation

Original Research

Published on 20 Jun 2025

Age-specific effects of synthetic cannabinoids on cognitive function and hippocampal gene expression in mice: insights from behavioral and molecular correlates

in Neuropharmacology

Kaixi Li
Yuanyuan Chen
Yawen Xu
Yuan Pang
Yongli Bao
Simeng Zhang
Xuesong Shi
Jingzhi Ran
Yanling Qiao
Yizhao Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1618929

2,563 views
1 citation

Review

Published on 19 Jun 2025

Plant-derived polyphenolic compounds for managing schizophrenia: mechanisms and therapeutic potential

in Neuropharmacology

Xiaolin Ji
Jianbo Chai
Sihan Zhao
Yonghou Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1605027

3,141 views
4 citations

Review

Published on 18 Jun 2025

Therapeutic potential of natural products in ischemic stroke: targeting angiogenesis

in Neuropharmacology

WenQiang Li
E. Liu
YiHao Zhou
ZhiChao Liao
DongYan Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1579172

4,384 views
2 citations

Correction

Published on 18 Jun 2025

Correction: Preventive strategies for reducing intraoperative awareness due to errors in anesthetic drug delivery systems: a narrative review

in Neuropharmacology

Qisheng Chen
Shixuan Peng
Wenjun Luo
Shuzhai Li
Zhiming Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1641124

892 views

Systematic Review

Published on 18 Jun 2025

Effectiveness and impact of intravenous magnesium sulfate in spinal surgery systematic review and meta-analysis

in Neuropharmacology

Zhaoguo Jin
Jianyong Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1624119

2,662 views
2 citations

Original Research

Published on 17 Jun 2025

Effects of previous steroid treatment on ischemic stroke outcomes: a propensity score-matched hospital analysis

in Neuropharmacology

Yasser Alatawi
Eman A. Alraddadi
Abdullah A. Alhifany
Faisal E. Alzahrani
Saud M. Alknawy
Nawaf M. Aljohani
Husun K. Kecheck
Alanoud K. Alaslab
Aser F. Alamri
Ahmed Aljabri

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1615170

2,435 views

Review

Published on 13 Jun 2025

Guarding minds: a narrative review on how n-acetylcyteine and ketones could shield sensitive patients from antibiotic neurotoxicity

in Neuropharmacology

Astrid Lounici

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1613152

2,426 views

Original Research

Published on 12 Jun 2025

Mitochondrial fission inhibitor Mdivi-1 alleviates lipopolysaccharide-induced parvalbumin interneurons dysregulation and cognitive impairments in a mouse model of sepsis-associated encephalopathy

in Neuropharmacology

Lei Dai
Shuxin Gu
Yibao Zhang
Siqi Ma
Peishan Wang
Jingyun Zhang
Cai Wang
Gaowei Su
Qun Fu
Wei Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1525028

2,191 views

Original Research

Published on 11 Jun 2025

Neuroprotective potential of quercetin in Alzheimer’s disease: targeting oxidative stress, mitochondrial dysfunction, and amyloid-β aggregation

in Neuropharmacology

Mohd Adnan
Arif Jamal Siddiqui
Fevzi Bardakci
Malvi Surti
Riadh Badraoui
Mitesh Patel

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1593264

4,778 views
7 citations

Original Research

Published on 11 Jun 2025

Association between SGLT-2 inhibitors and suicide risk in type 2 diabetes and bipolar: a real-world cohort study

in Neuropharmacology

En-Wei Chang
Jing-Yang Huang
Shih-Chang Lo
Chien-Ning Huang
Yi-Sun Yang
Edy Kornelius

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1601118

3,738 views

Review

Published on 10 Jun 2025

The role of the tryptophan metabolites in gut microbiota-brain axis and potential treatments: a focus on ischemic stroke

in Neuropharmacology

Na Qin
Xiaodi Xie
Rong Deng
Shiman Gao
Ting Zhu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1578018

4,469 views
6 citations

Original Research

Published on 10 Jun 2025

Kininogen enhances seizure susceptibility in mice possibly through bradykinin-induced modulation of calcium transients in glutamatergic and GABAergic neurons

in Neuropharmacology

Arijit Ghosh
Jiwen Huang
Qian Wang
Yanling Gong
Srishti Jain
Abhimanyu Thakur
Amiyangshu De
Meixi Gong
Yoshie Kiyohara
Jingtai Hu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1509837

3,242 views

General Commentary

Published on 09 Jun 2025

Commentary: Tauroursodeoxycholic acid regulates macrophage/monocyte distribution and improves spinal microenvironment to promote nerve regeneration through inhibiting NF-κB signaling pathway in spinal cord injury

in Neuropharmacology

Yi Chen
Lei Wu
Ruijie Ma

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1620107

1,610 views

Mini Review

Published on 09 Jun 2025

The role of Poly-ADP ribose polymerase (PARP) enzymes in chemotherapy-induced cognitive impairments – parallels with other neurodegenerative disorders

in Neuropharmacology

Dahlia A. Ordaz
Kalpna Gupta
Daniela A. Bota

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1615843

2,877 views
3 citations

Systematic Review

Published on 06 Jun 2025

Bibliometric analysis of NMDA receptors: 2015–2024

in Neuropharmacology

Yunsheng Liu
Yanyan Jia
Zengwei Kou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1614831

2,967 views
7 citations

Original Research

Published on 05 Jun 2025

Zileuton protects against arachidonic acid/5-lipoxygenase/leukotriene axis-mediated neuroinflammation in experimental traumatic brain injury

in Neuropharmacology

Xiaofeng Xu
Yan Wang
Xiaomei Li
Yang Yang
Dianxu Yang
Wenqi Tang
Jin Lu
Fang Yuan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1516836

4,106 views
2 citations

Case Report

Published on 05 Jun 2025

Case Report: Synergistic central nervous system depression of baclofen and pregabalin: clinical pharmacist-driven case analysis and case review

in Neuropharmacology

Yitong Xie
Danwei Wu
Peihao Jin
Lu Mao
Jiancun Zhen
Wei Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1598971

3,641 views
1 citation

Case Report

Published on 05 Jun 2025

Case Report: long-term clinical outcomes in RANBP2-associated acute necrotizing encephalopathy

in Neuropharmacology

Sonia A. Varghese
Olutayo I. Olubiyi
Irena Dujmovic Basuroski
Jordan Broman-Fulks
Emma B. Cardwell
Stephanie Peck
Qian-Zhou (JoJo) Yang
Sheng-Che Hung
Senyene E. Hunter

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1607682

2,595 views

2,620 articles

articles

Gut-brain axis in post-traumatic stress disorder: microbial - mediated mechanisms and new therapeutic approaches - A narrative review

Editorial: Innovative therapies against neurodegenerative disorders: from new active molecules to novel drug delivery systems

Ketogenic therapy for schizophrenia: evidence, mechanisms, and clinical perspectives

Research on the effects of GLP-1 receptor agonists in treating cognitive dysfunction and gait disorders in elderly patients with diabetes

Unveiling the therapeutic potential of natural products in Alzheimer’s disease: insights from in vitro, in vivo, and clinical studies

Network pharmacology-based prediction and “gut microbiota-inflammation-brain axis” validation of the active ingredients and potential mechanisms of Plantagins Herba for treating diabetes-related cognitive dysfunction

Age-specific effects of synthetic cannabinoids on cognitive function and hippocampal gene expression in mice: insights from behavioral and molecular correlates

Plant-derived polyphenolic compounds for managing schizophrenia: mechanisms and therapeutic potential

Therapeutic potential of natural products in ischemic stroke: targeting angiogenesis

Correction: Preventive strategies for reducing intraoperative awareness due to errors in anesthetic drug delivery systems: a narrative review

Effectiveness and impact of intravenous magnesium sulfate in spinal surgery systematic review and meta-analysis

Effects of previous steroid treatment on ischemic stroke outcomes: a propensity score-matched hospital analysis

Guarding minds: a narrative review on how n-acetylcyteine and ketones could shield sensitive patients from antibiotic neurotoxicity

Mitochondrial fission inhibitor Mdivi-1 alleviates lipopolysaccharide-induced parvalbumin interneurons dysregulation and cognitive impairments in a mouse model of sepsis-associated encephalopathy

Neuroprotective potential of quercetin in Alzheimer’s disease: targeting oxidative stress, mitochondrial dysfunction, and amyloid-β aggregation

Association between SGLT-2 inhibitors and suicide risk in type 2 diabetes and bipolar: a real-world cohort study

The role of the tryptophan metabolites in gut microbiota-brain axis and potential treatments: a focus on ischemic stroke

Kininogen enhances seizure susceptibility in mice possibly through bradykinin-induced modulation of calcium transients in glutamatergic and GABAergic neurons

Commentary: Tauroursodeoxycholic acid regulates macrophage/monocyte distribution and improves spinal microenvironment to promote nerve regeneration through inhibiting NF-κB signaling pathway in spinal cord injury

The role of Poly-ADP ribose polymerase (PARP) enzymes in chemotherapy-induced cognitive impairments – parallels with other neurodegenerative disorders

Bibliometric analysis of NMDA receptors: 2015–2024

Zileuton protects against arachidonic acid/5-lipoxygenase/leukotriene axis-mediated neuroinflammation in experimental traumatic brain injury

Case Report: Synergistic central nervous system depression of baclofen and pregabalin: clinical pharmacist-driven case analysis and case review

Case Report: long-term clinical outcomes in RANBP2-associated acute necrotizing encephalopathy