Frontiers in Pharmacology | Neuropharmacology

Original Research

Published on 04 Jun 2025

Early statin use might reduce the hemorrhagic transformation among acute ischemic stroke patients with recanalization therapy: a retrospective cohort study

in Neuropharmacology

Boyan Pan
Jiaying Lan
Xiaojun Li
Haoxuan Chen
Luankun Weng
Haoyou Xu
Yuanqi Zhao
Min Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1533905

1,839 views

Review

Published on 04 Jun 2025

Preventive strategies for reducing intraoperative awareness due to errors in anesthetic drug delivery systems: a narrative review

in Neuropharmacology

Qisheng Chen
Shixuan Peng
Wenjun Luo
Shuzhai Li
Zhiming Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1566185

3,877 views

Review

Published on 04 Jun 2025

Edaravone dexborneol compared to edaravone in the treatment of acute cerebral infarction: A meta-analysis

in Neuropharmacology

Yanshuo Shi
Yuanyuan Yue
Mi Wang
Huizhen Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1579742

2,551 views

Review

Published on 03 Jun 2025

Molecular mechanisms of neuroprotective effect of rutin

in Neuropharmacology

Zhang Chunmei
Wang Shuai

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1599167

4,906 views
7 citations

Original Research

Published on 03 Jun 2025

Functional ultrasound imaging and prewhitening analysis reveal MK-801-induced disruption of brain network connectivity

in Neuropharmacology

Erik Hakopian
Argishti E. Stepanian
Shan Zhong
Kofi A. Agyeman
Nancy Zepeda
Kevin Wu
Charles Liu
Darrin J. Lee
Vassilios Christopoulos

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1562102

2,182 views
3 citations

Correction

Published on 02 Jun 2025

Corrigendum: FGF21 inhibits ferroptosis caused by mitochondrial damage to promote the repair of peripheral nerve injury

in Neuropharmacology

Yao Yan
Xinyu Ran
Zihan Zhou
Yuting Gu
Rendu Wang
Chuanqi Qiu
Yinuo Sun
Jifeng Wang
Jian Xiao
Yingfeng Lu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1584515

1,399 views
1 citation

Study Protocol

Published on 30 May 2025

Effects of intravenous propofol combined with opioids on euphoria in patients undergoing painless gastrointestinal endoscopy: protocol for a randomized double-blind placebo-controlled trial

in Neuropharmacology

Youjia Yu
Qingfang Ma
Fengxia Du
Xiang Zhang
Chunyan Shao
Yan Li
Chuntao Ma

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1599684

2,447 views

Mini Review

Published on 30 May 2025

Research progress of quercetin on anti-anxiety and anti-depression

in Neuropharmacology

Teng Teng
Chunhong Song

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1621510

5,362 views
2 citations

Original Research

Published on 30 May 2025

Comparison of safety of lecanemab and aducanumab: a real-world disproportionality analysis using the FDA adverse event reporting system

in Neuropharmacology

Lingti Kong
Xiaohu Yang
Jian Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1593989

4,160 views
1 citation

Original Research

Published on 30 May 2025

Cisplatin induces hippocampal neurotoxicity and cognitive impairment in rats through neuroinflammation, oxidative stress, and overexpression of glutamatergic receptors mRNA

in Neuropharmacology

Ahmad Hamad Alhowail

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1592511

2,645 views
9 citations

Original Research

Published on 30 May 2025

Prenatal modulation of NADPH-oxidase reverses the deranged GABA switch and rescues behavioral deficits in valproate ASD rat model

in Neuropharmacology

Basma A. Yasseen
Hadeer Abdelkhalek
Sara Gohar
Yasmin Hatem
Hajar El-Sayed
Aya A. Elkhodiry
Aya Galal
Aya Samir
Nouran Al-Shehaby
Malak W. Elbenhawi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1571008

3,369 views

Editorial

Published on 27 May 2025

Editorial: Potential therapeutic approaches of female hormones in the brain

in Neuropharmacology

Pelin Kelicen Ugur
Mariagiovanna Cantone

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1617394

1,028 views

Original Research

Published on 27 May 2025

Tetramethylpyrazine enhances neuroprotection and plasticity in cerebral ischemia-reperfusion injury via RhoA/ROCK2 pathway inhibition

in Neuropharmacology

Yixin Zhang
Xin Zhang
Xiaocheng Shi
Weijing Liao
Junbin Lin

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1594283

2,913 views
2 citations

Review

Published on 26 May 2025

Brain injury biomarkers as targets for drugs development and personalized treatment for traumatic brain injury patients

in Neuropharmacology

Melissa Sandler
Sulaiman Almohaish
Gretchen M. Brophy

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1606174

1,928 views
1 citation

Original Research

Published on 23 May 2025

Therapeutic potential of a rhein-loaded self-nano-emulsifying drug delivery system in ameliorating LPS-induced depression: mechanistic insights and behavioral outcomes

in Neuropharmacology

Sachin More
Md Abdur Rashid
Prashant Kumar Tiwari
Rohini Kharwade
Yahya Alhamhoom
Turky Omar Asar
Mohammed Kaleem
Nilesh Mahajan
Ajay Pise
Kishor Danao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1577080

2,047 views
3 citations

Original Research

Published on 22 May 2025

Mangiferin mitigates neurological deficits and ferroptosis via NRF2/ARE pathway activation in cerebral ischemia-reperfusion rats

in Neuropharmacology

Chenjia Peng
Yang Zhang
Jiaqing Chai
Hengbo Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1577954

4,139 views
1 citation

Case Report

Published on 21 May 2025

Case Report: Pharmacokinetics of ceftazidime and avibactam during and after CRRT in an elderly patient and their associations with CNS adverse effects

in Neuropharmacology

Haiying Huang
Yun Han
Yinshan Wu
Feng Guo
Zhenwei Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1569715

2,830 views
1 citation

Perspective

Published on 20 May 2025

Benzodiazepine use in Spain: risks and perspectives on the current situation and proposals for their rational use

in Neuropharmacology

Carlos Roncero
Lorenzo Armenteros
Carmen Bellido-Cambrón
Amparo Bonilla-Guijarro
Emilio Gómez-Cibeira

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1547488

6,536 views
1 citation

Review

Published on 19 May 2025

Post stroke depression: pathogenesis and molecular mechanisms of natural product-based interventions

in Neuropharmacology

Haonan Gao
Yanyan Sai
Ruirui Shang
Xia Zhong
Linghui Kong
Jie Liu
Kedong Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1595160

4,111 views
6 citations

Original Research

Published on 16 May 2025

The regulation and mechanism of the cAMP-PKA pathway on PTSD-like behaviors exacerbated by alcohol exposure

in Neuropharmacology

Shuang Zhao
Wei Zhao
Ziqi Wang
Xiaofei Chen
Fangjiao Zong
Hanting Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1592187

2,588 views
1 citation

Original Research

Published on 16 May 2025

Tetramethylpyrazine attenuates the blood-brain barrier damage against ischemic stroke by targeting endothelin-1/Akt pathway in astrocytes

in Neuropharmacology

Minzhen Deng
Yuefang Cai
Yu Wang
Dafeng Hu
Yan Li
Zhenqiu Ning
Chengyi Wang
Sookja Kim Chung
Yan Huang
Jingbo Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1571552

2,267 views
2 citations

Original Research

Published on 15 May 2025

Comparative safety analysis of bevacizumab and alkylating agent in glioblastoma management – What have we learned recently?

in Neuropharmacology

Zhizhao Qu
Jiajia Zhao
Liu Yang
Yuanwei Fu
Rui Bai
Jinchuan Li
Hongqin Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1595642

2,312 views

Original Research

Published on 15 May 2025

Chronic administration of prebiotics and probiotics prevent pathophysiological hallmarks of Alzheimer’s disease in the cortex of APP/PS1 mice

in Neuropharmacology

Giorgia Sarti
Chiara Traini
Giada Magni
Selene Attorre
Giorgio Tognozzi
Edoardo Calussi
Maria Grazia Giovannini
Maria Giuliana Vannucchi
Daniele Lana

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1596469

3,276 views
2 citations

Original Research

Published on 14 May 2025

A ROS-responsive, aptamer-targeted graphene oxide nanocomposite for site-specific glutathione release in cerebral ischemia-reperfusion injury

in Neuropharmacology

Meiying Li
Lili Wei
Wenxu Liu
Jiawen Wang
Qiujie Lu
Xianjue Chen
Lee Yong Lim
Jingxin Mo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1543870

2,068 views
2 citations

2,620 articles

articles

Early statin use might reduce the hemorrhagic transformation among acute ischemic stroke patients with recanalization therapy: a retrospective cohort study

Preventive strategies for reducing intraoperative awareness due to errors in anesthetic drug delivery systems: a narrative review

Edaravone dexborneol compared to edaravone in the treatment of acute cerebral infarction: A meta-analysis

Molecular mechanisms of neuroprotective effect of rutin

Functional ultrasound imaging and prewhitening analysis reveal MK-801-induced disruption of brain network connectivity

Corrigendum: FGF21 inhibits ferroptosis caused by mitochondrial damage to promote the repair of peripheral nerve injury

Effects of intravenous propofol combined with opioids on euphoria in patients undergoing painless gastrointestinal endoscopy: protocol for a randomized double-blind placebo-controlled trial

Research progress of quercetin on anti-anxiety and anti-depression

Comparison of safety of lecanemab and aducanumab: a real-world disproportionality analysis using the FDA adverse event reporting system

Cisplatin induces hippocampal neurotoxicity and cognitive impairment in rats through neuroinflammation, oxidative stress, and overexpression of glutamatergic receptors mRNA

Prenatal modulation of NADPH-oxidase reverses the deranged GABA switch and rescues behavioral deficits in valproate ASD rat model

Editorial: Potential therapeutic approaches of female hormones in the brain

Tetramethylpyrazine enhances neuroprotection and plasticity in cerebral ischemia-reperfusion injury via RhoA/ROCK2 pathway inhibition

Brain injury biomarkers as targets for drugs development and personalized treatment for traumatic brain injury patients

Therapeutic potential of a rhein-loaded self-nano-emulsifying drug delivery system in ameliorating LPS-induced depression: mechanistic insights and behavioral outcomes

Mangiferin mitigates neurological deficits and ferroptosis via NRF2/ARE pathway activation in cerebral ischemia-reperfusion rats

Case Report: Pharmacokinetics of ceftazidime and avibactam during and after CRRT in an elderly patient and their associations with CNS adverse effects

Benzodiazepine use in Spain: risks and perspectives on the current situation and proposals for their rational use

Post stroke depression: pathogenesis and molecular mechanisms of natural product-based interventions

The regulation and mechanism of the cAMP-PKA pathway on PTSD-like behaviors exacerbated by alcohol exposure

Tetramethylpyrazine attenuates the blood-brain barrier damage against ischemic stroke by targeting endothelin-1/Akt pathway in astrocytes

Comparative safety analysis of bevacizumab and alkylating agent in glioblastoma management – What have we learned recently?

Chronic administration of prebiotics and probiotics prevent pathophysiological hallmarks of Alzheimer’s disease in the cortex of APP/PS1 mice

A ROS-responsive, aptamer-targeted graphene oxide nanocomposite for site-specific glutathione release in cerebral ischemia-reperfusion injury