Frontiers in Pharmacology | Pharmacoepidemiology

Review

Published on 18 Aug 2025

Metformin in polycystic ovary syndrome: unraveling multi-stage therapeutic mechanisms from puberty to long-term health outcomes

in Pharmacoepidemiology

Weiwei Zeng
Yuning Luo
Juanfeng Ou
Dali Gan
Min Huang
Brian Tomlinson
Yiming Jiang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1654372

158 views

Original Research

Published on 18 Aug 2025

Trends in prescription opioid use in Europe: A DARWIN EU® multinational cohort study including seven European countries

in Pharmacoepidemiology

Junqing Xie
Mike Du
Yuchen Guo
Cesar Barboza
James T. Brash
Antonella Delmestri
Talita Duarte-Salles
Jasmine Gratton
Romain Griffier
Raivo Kolde

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1608051

172 views

Brief Research Report

Accepted on 14 Aug 2025

Trends in the Use of Validated Claims-Based Algorithms in Japanese Post-Marketing Database Studies

in Pharmacoepidemiology

Chieko Ishiguro
Takahiro Nonaka

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1642490

Original Research

Published on 13 Aug 2025

Statins for polycystic ovary syndrome in varying resource settings: a phenome-wide association study and evidence synthesis

in Pharmacoepidemiology

Laura A. Zahn
Taylor D. Budine
Jana K. Shirey-Rice
Meghan M. Joly
Robert S. Wallis
Gordon R. Bernard
Kenneth J. Holroyd
Jill M. Pulley
Rebecca N. Jerome

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1562587

479 views

Original Research

Published on 13 Aug 2025

Unveiling the hidden risk of caspofungin: insights from three adverse event reporting systems and network pharmacology integration

in Pharmacoepidemiology

Zhengfu Li
Zhiwei Cui
De Xie
Fan Zou
Chengyu Zhu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1632488

305 views

Original Research

Published on 13 Aug 2025

Incident gabapentin prescribing associated with opioid and benzodiazepine/Z-drug prescribing – a population-based longitudinal study in primary care

in Pharmacoepidemiology

Kristjan Linnet
Bjarni Pall Linnet Runolfsson
Johann Agust Sigurdsson
Larus Steinthor Gudmundsson

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1583415

466 views

Original Research

Accepted on 12 Aug 2025

Use of Over-the-Counter Antiallergic Products -Analysis of Sales Data in Poland from 2020 to 2023

in Pharmacoepidemiology

Łukasz Dudziński
Marcin Weiner
Tomasz Kubiak
Julia Grochowska
Robert Gałązkowski
Lukasz Czyzewski

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1649349

119 views

Original Research

Accepted on 12 Aug 2025

Tracing the evolution of polypharmacy and contraindicated drug‒drug interactions in people living with HIV in Belgium

in Pharmacoepidemiology

Victoria Lopez Delhoulle
Li-Cécile Destordeur
Nathalie Maes
Karine Fombellida
Majdouline El Moussaoui
Gilles Darcis

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1632108

Original Research

Published on 08 Aug 2025

Knowledge and usage patterns of clotrimazole vaginal cream and tablet amongst females: a cross-sectional study

in Pharmacoepidemiology

Obi Peter Adigwe
Godspower Onavbavba
Chiamaka Frances Okeke

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1484238

578 views

Original Research

Published on 08 Aug 2025

Sex-specific risk signals and onset patterns of drug-induced peripheral neuralgia: a 20-year pharmacovigilance analysis based on FAERS real-world dat

in Pharmacoepidemiology

Xianyan Wang
Min Deng
Wanjun Liao
Yiwen Quan
Xiaoxue Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1628362

446 views

Mini Review

Accepted on 05 Aug 2025

Polypharmacy Driven Synergistic Toxicities in Elderly Breast Cancer Chemotherapy Drug management and adverse drug reactions: A mini review

in Pharmacoepidemiology

Xiran Wang
Jin Yang
Jieying Zhang
Hong Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1654353

164 views

Original Research

Accepted on 05 Aug 2025

Cost-effectiveness analysis of pembrolizumab plus chemotherapy versus placebo plus chemotherapy for patients with previously untreated locally recurrent inoperable or metastatic triple-negative breast cancer in China

in Pharmacoepidemiology

Yibing Hou
Shuo Yang
Xiaohui Wang
Shan Zhao
Huanlong Liu
Shuo Kang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1654177

189 views

Original Research

Published on 05 Aug 2025

Mining and evaluation of security alert signals of neuroprotective agents based on the Jinan adverse event reporting system database: a retrospective study

in Pharmacoepidemiology

Yu-yao Guan
Jing Yang
Ying-mei Qi
Chao Song
Lei Zheng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1529923

372 views

Original Research

Published on 05 Aug 2025

The AMerican PREGNANcy Mother–Child CohorT: description and prevalence of baseline outcomes and medication dispensing

in Pharmacoepidemiology

Lisiane F. Leal
Odile Sheehy
Jessica Gorgui
Anick Bérard

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1608403

538 views

Brief Research Report

Published on 01 Aug 2025

Adefovir dipivoxil-associated Fanconi syndrome combined with peripheral neuropathy: a case report and literature review

in Pharmacoepidemiology

Shanshan Fu
Guanao Wu
Yuanqi Zhao
Min Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1585126

457 views

Original Research

Published on 01 Aug 2025

Comparative clinical outcomes of acenocoumarol versus direct oral anticoagulants (DOACs) and warfarin in patients with atrial fibrillation: real-world-evidence (SIESTA-A study)

in Pharmacoepidemiology

Ma Carmen Montero-Balosa
Juan A. Limón-Mora
Ana Leal-Atienza
Beatriz García-Robredo
Pablo Sánchez-Villegas
Rebeca Isabel-Gómez
Ma José Aguado-Romeo
Luis Gabriel Luque Romero
Ma Teresa Molina-López

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1548298

516 views