Frontiers in Pharmacology | Pharmacoepidemiology

Original Research

Published on 19 Nov 2025

Ivabradine, atrial fibrillation and stroke: a combined meta-analysis and FAERS disproportionality analysis

in Pharmacoepidemiology

Alberto Spadotto
Michele Fusaroli
Maria Carelli
Elena Nardi
Martina Amadori
Giulia Massaro
Veronica De Angelis
Milo Gatti
Valerio Ciubine
Emanuel Raschi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1638923

919 views

Original Research

Published on 18 Nov 2025

Constructing an evaluation framework for primary pharmacovigilance systems in developing countries: a case study from China

in Pharmacoepidemiology

Shuang Lei
Shuzhi Lin
Xiaoying Zhu
Wei Liu
Qian Liu
Lin Yin
Bianling Feng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1657574

709 views

Original Research

Accepted on 14 Nov 2025

Pharmacovigilance Study on Neurological Adverse Reactions of Proteasome Inhibitors in the FDA Adverse Event Reporting System

in Pharmacoepidemiology

Shuyue Li
Tao Ling
Yan Liu
Jun Li

Frontiers in Pharmacology

244 views

Original Research

Published on 13 Nov 2025

Evaluation of standard use of intravenous infusion in 25 general hospitals in Shanxi province based on factor analysis and cluster analysis

in Pharmacoepidemiology

Lin Chen
Song Wang
Jinju Duan
Rong Yu
Ruigang Hou
Donghong Yin

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1708461

633 views

Original Research

Published on 12 Nov 2025

Comparative safety analysis of Riluzole, Edaravone and Tofersen in ALS management: insights from FAERS database

in Pharmacoepidemiology

Shuang Guan
Sicun Wang
Yinli Shi
Yuanyuan Leng
Yu Ming
Zhiyong Hou
Yanan Yu
Zhong Wang
Jun Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1687698

2,712 views

Original Research

Published on 11 Nov 2025

HPV vaccine-related thyroid adverse events: temporal patterns and reporting trends

in Pharmacoepidemiology

Liying Song
Jingkai Di
Jiaolin Fan
Rongrong Xi
Siyu Liang
Guosheng Duan
Yuanzheng Ding
Shuai Hao
Jing Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1664697

3,255 views

Original Research

Published on 11 Nov 2025

A real-world pharmacovigilance study of FDA adverse event reporting system (FAERS) events for etrasimod

in Pharmacoepidemiology

Yingxiu Wu
Wei Ke
Huibiao Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1693090

1,515 views

Original Research

Published on 10 Nov 2025

The real-world safety profile of ranolazine: pharmacovigilance analysis of the FAERS database

in Pharmacoepidemiology

Zujun Wen
Xiang Liu
Yanbin Yi
Gengliang Lin
Peng Liu
Tingting Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1702875

1,319 views

Original Research

Published on 10 Nov 2025

The correlation between the use of ondansetron and mortality in sepsis associated encephalopathy patients: a retrospective ICU cohort study

in Pharmacoepidemiology

Shuo Yang
Yi-Qu Wei
Ya-Zhou Liu
Xiao-Lin Wang
Jin-Xia Gao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1712328

1,138 views

Original Research

Published on 10 Nov 2025

Disproportionality evaluation of adverse effects and suicide/self-injury risk factors associated with vortioxetine: a large-scale pharmacovigilance study

in Pharmacoepidemiology

Xiangyu Li
Fang Yang
Lingjing Yuan
Li Ma

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1689634

1,148 views

Original Research

Accepted on 06 Nov 2025

Pharmacovigilance Signal Detection of Psychiatric Adverse Events Induced by Third-Generation Antiepileptic Drugs in Children

in Pharmacoepidemiology

Wenfang Sun
Hua Chen
Yali Li
Binbin Xia
Liushui Li
Jing Chen
Yang Liu
Jingyao Pang
Fang Liu

Frontiers in Pharmacology

265 views

Original Research

Published on 03 Nov 2025

Medical dispensation in La Rioja, Spain: epidemiology and its relationship with social determinants: a descriptive study

in Pharmacoepidemiology

Gonzalo Aparicio-Rodríguez
Raúl Juárez-Vela
Amaya Burgos-Esteban
Consuelo Sancho-Sánchez
José Ángel Santos-Sanchez
Noelia Navas-Echazarreta
Ana Cobos-Rincón
Antonio Cardoso-Muñoz
Regina Ruiz de Viñaspre-Hernández
Ignacio M. Larrayoz

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1667148

1,233 views

Original Research

Published on 29 Oct 2025

Implementation of pharmacist recommendations following medication reviews in aged care

in Pharmacoepidemiology

Noah C. Ramsey
Gregory M. Peterson
Corinne Mirkazemi
Mohammed S. Salahudeen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1690600

1,178 views

Original Research

Published on 23 Oct 2025

Implementation and impact analysis of a clinical pharmacy ambulatory: a two-year experience

in Pharmacoepidemiology

Daniele Mengato
Laura Camuffo
Federica Todino
Luisella Cordiano
Domenica Condello
Catia Bucciol
Franca Benini
Francesco Paolo Russo
Alberto Cipriani
Stefano Sartori

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1706056

1,197 views

Original Research

Published on 21 Oct 2025

Drug-associated serotonin syndrome in elderly patients: a comprehensive disproportionality analysis based on the FAERS database

in Pharmacoepidemiology

Xiaozhi Li
Xiaofen Wen
Hongbo Fu
Xiaobing Hong
Danxia Lin
Xiaoyan Li
Zhikun Liang
Mengna Wang
Xihui Yu
Yanqiong Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1700469

1,488 views

Original Research

Published on 20 Oct 2025

Real-world feasibility of co-administration of RSV, COVID-19, and influenza vaccines in older adults: a VAERS-based analysis

in Pharmacoepidemiology

Zhen Wei
Shilun Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1682119

2,448 views

Original Research

Published on 16 Oct 2025

Personalizing voriconazole dosing in Chinese hematological patients: CYP2C19 phenotype and albumin-bilirubin grade as key predictors of trough concentrations

in Pharmacoepidemiology

Lin Hu
Xi Tang
Yanfei Li
Juanjuan Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1667461

854 views

Original Research

Published on 16 Oct 2025

Prediction of long-term adherence to direct oral anti-coagulants in patients with atrial fibrillation using first-order Markov models

in Pharmacoepidemiology

Elias Edward Tannous
Shlomo Selitzky
Shlomo Vinker
Nicola Toukan
David Stepensky
Eyal Schwarzberg

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1673919

936 views

Original Research

Published on 08 Oct 2025

Prevalence and patterns of dietary supplement use and potential drug interactions among older adults in Saudi Arabia

in Pharmacoepidemiology

Wael Y. Khawagi
Majd M. Alghamdi
Laila M. Alfalqi
Atheer A. Alzahrani
Sara K. Alotaibi
Joud J. Alsuwat
Fahad H. Baali
Wadia S. Alruqayb
Sofa D. Alfian
Abdullah A. Alshehri

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1654337

2,298 views

Original Research

Published on 08 Oct 2025

Integrated pharmacovigilance of fentanyl: multinational analysis reveals novel safety signals and demographic-specific risk profiles

in Pharmacoepidemiology

Junge Zhang
Wenxin Wang
Zihui Lu
Changshun Huang
Hehe Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1700112

1,737 views

Original Research

Published on 02 Oct 2025

A comprehensive analysis of adverse drug reactions in 2020–2023: case studies

in Pharmacoepidemiology

Jinghui Zhai
Hongzhe Yan
Jinping Zhang
Huiyu Yan
Jie Ma
Sixi Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1628347

3,300 views
2 citations

Original Research

Published on 29 Sep 2025

The safety and efficacy of long-term use of calcitonin analogs in the treatment of osteoporosis in the elderly: a pharmacovigilance and RCT meta-analysis

in Pharmacoepidemiology

Lingjie Tan
Bin Sheng
Sui Deng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1514387

3,811 views
1 citation

Original Research

Published on 25 Sep 2025

Profiles and influencing factors of pulmonary fibrosis associated with biologic and conventional disease-modifying antirheumatic drugs for autoimmune diseases: a disproportionality study based on FAERS and VigiAccess

in Pharmacoepidemiology

Xinyue Zhang
Xinhui Wu
Cheng Luo
Chun Yang
Nan Jia
Jiayi He
Qian Chen
Fei Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1604895

2,427 views

Systematic Review

Published on 24 Sep 2025

Pharmacogenetics of metamizole-induced agranulocytosis: a systematic review and drug regulation implications

in Pharmacoepidemiology

Giovana Fernanda Santos Fidelis
Carolina Dagli-Hernandez
Romina P. Martinelli
Jefman Efendi Marzuki
Baharuddin Baharuddin
Qun-Ying Yue
Brian Edwards
Eder de Carvalho Pincinato
Patricia Moriel

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1624044

3,172 views

571 articles

articles

Ivabradine, atrial fibrillation and stroke: a combined meta-analysis and FAERS disproportionality analysis

Constructing an evaluation framework for primary pharmacovigilance systems in developing countries: a case study from China

Pharmacovigilance Study on Neurological Adverse Reactions of Proteasome Inhibitors in the FDA Adverse Event Reporting System

Evaluation of standard use of intravenous infusion in 25 general hospitals in Shanxi province based on factor analysis and cluster analysis

Comparative safety analysis of Riluzole, Edaravone and Tofersen in ALS management: insights from FAERS database

HPV vaccine-related thyroid adverse events: temporal patterns and reporting trends

A real-world pharmacovigilance study of FDA adverse event reporting system (FAERS) events for etrasimod

The real-world safety profile of ranolazine: pharmacovigilance analysis of the FAERS database

The correlation between the use of ondansetron and mortality in sepsis associated encephalopathy patients: a retrospective ICU cohort study

Disproportionality evaluation of adverse effects and suicide/self-injury risk factors associated with vortioxetine: a large-scale pharmacovigilance study

Pharmacovigilance Signal Detection of Psychiatric Adverse Events Induced by Third-Generation Antiepileptic Drugs in Children

Medical dispensation in La Rioja, Spain: epidemiology and its relationship with social determinants: a descriptive study

Implementation of pharmacist recommendations following medication reviews in aged care

Implementation and impact analysis of a clinical pharmacy ambulatory: a two-year experience

Drug-associated serotonin syndrome in elderly patients: a comprehensive disproportionality analysis based on the FAERS database

Real-world feasibility of co-administration of RSV, COVID-19, and influenza vaccines in older adults: a VAERS-based analysis

Personalizing voriconazole dosing in Chinese hematological patients: CYP2C19 phenotype and albumin-bilirubin grade as key predictors of trough concentrations

Prediction of long-term adherence to direct oral anti-coagulants in patients with atrial fibrillation using first-order Markov models

Prevalence and patterns of dietary supplement use and potential drug interactions among older adults in Saudi Arabia

Integrated pharmacovigilance of fentanyl: multinational analysis reveals novel safety signals and demographic-specific risk profiles

A comprehensive analysis of adverse drug reactions in 2020–2023: case studies

The safety and efficacy of long-term use of calcitonin analogs in the treatment of osteoporosis in the elderly: a pharmacovigilance and RCT meta-analysis

Profiles and influencing factors of pulmonary fibrosis associated with biologic and conventional disease-modifying antirheumatic drugs for autoimmune diseases: a disproportionality study based on FAERS and VigiAccess

Pharmacogenetics of metamizole-induced agranulocytosis: a systematic review and drug regulation implications