Frontiers in Pharmacology | Pharmacoepidemiology

Original Research

Published on 16 Oct 2025

Prediction of long-term adherence to direct oral anti-coagulants in patients with atrial fibrillation using first-order Markov models

in Pharmacoepidemiology

Elias Edward Tannous
Shlomo Selitzky
Shlomo Vinker
Nicola Toukan
David Stepensky
Eyal Schwarzberg

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1673919

1,134 views

Original Research

Published on 08 Oct 2025

Prevalence and patterns of dietary supplement use and potential drug interactions among older adults in Saudi Arabia

in Pharmacoepidemiology

Wael Y. Khawagi
Majd M. Alghamdi
Laila M. Alfalqi
Atheer A. Alzahrani
Sara K. Alotaibi
Joud J. Alsuwat
Fahad H. Baali
Wadia S. Alruqayb
Sofa D. Alfian
Abdullah A. Alshehri

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1654337

2,965 views

Original Research

Published on 08 Oct 2025

Integrated pharmacovigilance of fentanyl: multinational analysis reveals novel safety signals and demographic-specific risk profiles

in Pharmacoepidemiology

Junge Zhang
Wenxin Wang
Zihui Lu
Changshun Huang
Hehe Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1700112

2,097 views

Original Research

Published on 02 Oct 2025

A comprehensive analysis of adverse drug reactions in 2020–2023: case studies

in Pharmacoepidemiology

Jinghui Zhai
Hongzhe Yan
Jinping Zhang
Huiyu Yan
Jie Ma
Sixi Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1628347

4,189 views
2 citations

Original Research

Published on 29 Sep 2025

The safety and efficacy of long-term use of calcitonin analogs in the treatment of osteoporosis in the elderly: a pharmacovigilance and RCT meta-analysis

in Pharmacoepidemiology

Lingjie Tan
Bin Sheng
Sui Deng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1514387

4,423 views
4 citations

Original Research

Published on 25 Sep 2025

Profiles and influencing factors of pulmonary fibrosis associated with biologic and conventional disease-modifying antirheumatic drugs for autoimmune diseases: a disproportionality study based on FAERS and VigiAccess

in Pharmacoepidemiology

Xinyue Zhang
Xinhui Wu
Cheng Luo
Chun Yang
Nan Jia
Jiayi He
Qian Chen
Fei Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1604895

2,732 views

Systematic Review

Published on 24 Sep 2025

Pharmacogenetics of metamizole-induced agranulocytosis: a systematic review and drug regulation implications

in Pharmacoepidemiology

Giovana Fernanda Santos Fidelis
Carolina Dagli-Hernandez
Romina P. Martinelli
Jefman Efendi Marzuki
Baharuddin Baharuddin
Qun-Ying Yue
Brian Edwards
Eder de Carvalho Pincinato
Patricia Moriel

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1624044

3,990 views

Systematic Review

Published on 24 Sep 2025

Dental safety of short-term doxycycline use in children under 8 years: a systematic review and meta-analysis

in Pharmacoepidemiology

Anusiga Sigamani Rajan
Muthu Gopal
Madhumidha Periyathambi
Vijesh Sreedhar Kuttiatt

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1646638

3,606 views

Original Research

Published on 23 Sep 2025

Impact of post-admission changes in potentially inappropriate medication use on risk of subsequent hospitalization among nursing home residents

in Pharmacoepidemiology

Jing Zhao
Hyunwoo Chae
Young-Mi Ah
Kwanghee Jun
Ju-Yeun Lee

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1655681

2,196 views
1 citation

Systematic Review

Published on 22 Sep 2025

Efficacy and safety of aldosterone synthase inhibitors for uncontrolled hypertension: a meta-analysis of randomized controlled trials and systematic review

in Pharmacoepidemiology

Yifan Gao
Xu Mu
Xingxue Pang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1664810

4,151 views
1 citation

Original Research

Published on 22 Sep 2025

Burden of drug use disorders from 1990 to 2021 and projection to 2050 in China: findings from the 2021 global burden of disease study

in Pharmacoepidemiology

Shuzheng Yu
Yanting Chen
Shaohua Huang
Bing Wang
Qingrong Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1625873

2,815 views

Original Research

Published on 22 Sep 2025

Tracing the evolution of polypharmacy and contraindicated drug‒drug interactions in people living with HIV in Belgium

in Pharmacoepidemiology

Victoria Lopez Delhoulle
Li-Cécile Destordeur
Nathalie Maes
Karine Fombellida
Majdouline El Moussaoui
Gilles Darcis

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1632108

1,553 views

Brief Research Report

Published on 19 Sep 2025

Single-versus multiple-inhaler triple therapy in patients with COPD in Spain: a retrospective cohort study comparing adherence, persistence, risk of exacerbations and economic outcomes

in Pharmacoepidemiology

M. Asunción González-González
M. Aránzazu Pedrosa-Naudín
Diego Fernández-Lázaro
Isabel Díaz Planelles
F. Javier Álvarez
Eduardo Gutiérrez-Abejón

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1642470

3,197 views
2 citations

Original Research

Published on 17 Sep 2025

Drug-induced agranulocytosis: a disproportionality analysis and umbrella review

in Pharmacoepidemiology

Yajie Lu
Bin Wu
Kunyu Li
Zhonglin Liu
Yuxi Chen
Ting Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1641747

3,720 views
1 citation

Original Research

Published on 16 Sep 2025

Difference in outcome event coverage between insurance-based and hospital-based databases: a methodological study of diabetes drug use and cardiovascular events in Japan

in Pharmacoepidemiology

Takashi Ando
Tomoaki Hasegawa
Chieko Ishiguro
Jun Komiyama
Toshiki Kuno
Masao Iwagami

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1642522

2,844 views

Original Research

Published on 12 Sep 2025

Global burden and trends of adverse effects of medical treatment, 1990–2021: an analysis from the global burden of disease study 2021

in Pharmacoepidemiology

Keqing Zhang
Yuhai Gao
Yunfei Lu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1655864

3,639 views

Original Research

Published on 09 Sep 2025

Urinary tract infections in women in Catalonia, Spain: a population-based observational cohort study in primary care

in Pharmacoepidemiology

Silvia Fernández-García
Ana Moragas
Maria Giner-Soriano
Rosa Morros
Dan Ouchi
Ana García-Sangenís
Carl Llor

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1593910

2,450 views
1 citation

Brief Research Report

Published on 02 Sep 2025

Trends in the use of validated claims-based algorithms in Japanese post-marketing database studies

in Pharmacoepidemiology

Chieko Ishiguro
Takahiro Nonaka

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1642490

1,427 views

Original Research

Published on 01 Sep 2025

Comparative assessment of antibacterial drugs used at the hospital level before and during COVID-19, according to the WHO AWaRe classification

in Pharmacoepidemiology

Aigerim A. Balapasheva
Gaziza A. Smagulova
Aigul Z. Mussina
Daniyar S. Dilmagambetov
Kalzhan Zh. Yermekbayeva
Mirsaid S. Kelimberdiev
Mariya S. Kulnazarova
Lazzat S. Balymbetova
Liliya E. Ziganshina

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1642830

1,727 views

Original Research

Published on 29 Aug 2025

High persistence of biologic therapy in patients with Psoriatic arthritis: a real-world evidence from a high-complexity hospital in Colombia

in Pharmacoepidemiology

Andrés Hormaza-Jaramillo
Leidy Johanna Hurtado-Bermudez
Daniela Peñaloza Gonzalez
Tatiana Delgado-Mora

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1559168

2,525 views

Opinion

Published on 29 Aug 2025

Is it appropriate to conduct a disproportionality analysis using a spontaneous reporting database to investigate whether drug-related adverse events are dose-dependent?

in Pharmacoepidemiology

Yoshihiro Noguchi
Tomoya Tachi
Tomoaki Yoshimura

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1563524

1,683 views
1 citation

Brief Research Report

Published on 29 Aug 2025

Perception of falsified and counterfeit medicines among adults living in Mexico City and the metropolitan area: an underappreciated health risk

in Pharmacoepidemiology

Jessica Citlalli Celaya Pérez
Tania Ibargüengoitia Larios
Maria de los Angeles Frías Fernández
Manuel Abraham Gómez Martínez
Kenneth Rubio Carrasco
Raúl Lugo Villegas
Arely Vergara-Castañeda

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1654822

2,032 views

Mini Review

Published on 26 Aug 2025

Polypharmacy driven synergistic toxicities in elderly breast cancer chemotherapy drug management and adverse drug reactions: a mini review

in Pharmacoepidemiology

Xiran Wang
Jin Yang
Jieying Zhang
Hong Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1654353

3,506 views
2 citations

Original Research

Published on 22 Aug 2025

Use of over-the-counter antiallergic products–analysis of sales data in Poland from 2020 to 2023

in Pharmacoepidemiology

Łukasz Dudziński
Marcin Weiner
Tomasz Kubiak
Julia Grochowska
Robert Gałązkowski
Lukasz Czyzewski

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1649349

2,316 views
1 citation

602 articles

articles

Prediction of long-term adherence to direct oral anti-coagulants in patients with atrial fibrillation using first-order Markov models

Prevalence and patterns of dietary supplement use and potential drug interactions among older adults in Saudi Arabia

Integrated pharmacovigilance of fentanyl: multinational analysis reveals novel safety signals and demographic-specific risk profiles

A comprehensive analysis of adverse drug reactions in 2020–2023: case studies

The safety and efficacy of long-term use of calcitonin analogs in the treatment of osteoporosis in the elderly: a pharmacovigilance and RCT meta-analysis

Profiles and influencing factors of pulmonary fibrosis associated with biologic and conventional disease-modifying antirheumatic drugs for autoimmune diseases: a disproportionality study based on FAERS and VigiAccess

Pharmacogenetics of metamizole-induced agranulocytosis: a systematic review and drug regulation implications

Dental safety of short-term doxycycline use in children under 8 years: a systematic review and meta-analysis

Impact of post-admission changes in potentially inappropriate medication use on risk of subsequent hospitalization among nursing home residents

Efficacy and safety of aldosterone synthase inhibitors for uncontrolled hypertension: a meta-analysis of randomized controlled trials and systematic review

Burden of drug use disorders from 1990 to 2021 and projection to 2050 in China: findings from the 2021 global burden of disease study

Tracing the evolution of polypharmacy and contraindicated drug‒drug interactions in people living with HIV in Belgium

Single-versus multiple-inhaler triple therapy in patients with COPD in Spain: a retrospective cohort study comparing adherence, persistence, risk of exacerbations and economic outcomes

Drug-induced agranulocytosis: a disproportionality analysis and umbrella review

Difference in outcome event coverage between insurance-based and hospital-based databases: a methodological study of diabetes drug use and cardiovascular events in Japan

Global burden and trends of adverse effects of medical treatment, 1990–2021: an analysis from the global burden of disease study 2021

Urinary tract infections in women in Catalonia, Spain: a population-based observational cohort study in primary care

Trends in the use of validated claims-based algorithms in Japanese post-marketing database studies

Comparative assessment of antibacterial drugs used at the hospital level before and during COVID-19, according to the WHO AWaRe classification

High persistence of biologic therapy in patients with Psoriatic arthritis: a real-world evidence from a high-complexity hospital in Colombia

Is it appropriate to conduct a disproportionality analysis using a spontaneous reporting database to investigate whether drug-related adverse events are dose-dependent?

Perception of falsified and counterfeit medicines among adults living in Mexico City and the metropolitan area: an underappreciated health risk

Polypharmacy driven synergistic toxicities in elderly breast cancer chemotherapy drug management and adverse drug reactions: a mini review

Use of over-the-counter antiallergic products–analysis of sales data in Poland from 2020 to 2023