Brief Research Report

Accepted on 22 Nov 2024

Clinical implications of a gain of function genetic polymorphism in DPYD (rs4294451) in colorectal cancer patients treated with fluoropyrimidines

in Pharmacogenetics and Pharmacogenomics

Elena De Mattia
Jerry Polesel
Lucia Scarabel
Erika Cecchin

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1516375

Review

Accepted on 20 Nov 2024

Advancements in Precision Medicine: Multi-omics Approach for Tailored Metformin Treatment in Type 2 Diabetes

in Pharmacogenetics and Pharmacogenomics

Najeha Rizwana Anwardeen
Khaled Naja
Mohamed A. Elrayess

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1506767

Original Research

Published on 20 Nov 2024

Metabolic pathways, genomic alterations, and post-translational modifications in pulmonary hypertension and cancer as therapeutic targets and biomarkers

in Pharmacogenetics and Pharmacogenomics

Xiujin Zhang
Zhiqing Fu
Haijun Wang
Li Sheng

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1490892

109 views

Review

Accepted on 19 Nov 2024

Pediatric Flecainide Pharmacogenomics: A Roadmap to Deliver Precision Based Care to Pediatrics Arrhythmias

in Pharmacogenetics and Pharmacogenomics

Jonathan Burton Wagner
Roanld Palmen
Mollie Walton

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1477485

Original Research

Published on 18 Nov 2024

Investigation on regulation of N-acetyltransferase 2 expression by nuclear receptors in human hepatocytes

in Pharmacogenetics and Pharmacogenomics

Kyung U. Hong
Anthony P. Aureliano
Kennedy M. Walls
David W. Hein

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1488367

223 views

Original Research

Published on 15 Nov 2024

Population pharmacokinetic study of the effect of polymorphisms in the ABCB1 and CES1 genes on the pharmacokinetics of dabigatran

in Pharmacogenetics and Pharmacogenomics

Zhuan Yang
Wen Rui Tan
Qin Li
Ying Wang
Shijing Liu
Lu Chen
Yan Zhou
Chen Zeng
Yan Zeng
Yun Xiong

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1454612

156 views

Original Research

Published on 14 Nov 2024

Novel genomic variants influencing methotrexate delayed clearance in pediatric patients with acute lymphoblastic leukemia

in Pharmacogenetics and Pharmacogenomics

Jung Yoon Choi
Hoshik Kwon
Hyery Kim
Kyung Taek Hong
Youngeun Ma
Kyung-Nam Koh
Sunmin Yun
Keon Hee Yoo
Sang Hoon Song
Ho Joon Im

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1480657

169 views

Original Research

Accepted on 13 Nov 2024

Integration of pharmacogenetic data in Epic Genomic Module drives best practice alerts

in Pharmacogenetics and Pharmacogenomics

Kimberly Newsom
Bradley Hall
Katherine Martinez
Scott Nelson
Petr Starostik
Khoa Nguyen

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1458095

140 views

Review

Published on 12 Nov 2024

Tumor microenvironment and cancer metastasis: molecular mechanisms and therapeutic implications

in Pharmacogenetics and Pharmacogenomics

Cigir Biray Avci
Bakiye Goker Bagca
Masoud Nikanfar
Leila Sabour Takanlou
Maryam Sabour Takanlou
Alireza Nourazarian

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1442888

339 views

Original Research

Accepted on 08 Nov 2024

Paromomycin targets HDAC1-mediated SUMOylation and IGF1R translocation in glioblastoma

in Pharmacogenetics and Pharmacogenomics

Yuejie Guo
Zhong Min
Luo Ning

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1490878

Original Research

Accepted on 01 Nov 2024

Comparing Commercial Pharmacogenetic Testing Results and Recommendations for Antidepressants with Established CPIC Guidelines

in Pharmacogenetics and Pharmacogenomics

Tiffany T Nguyen
Emili Jeanne-Watts Leary
Joshua T Lee
Sanjay K Shukla
Sara A Griesbach

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1500235

112 views

Original Research

Published on 01 Nov 2024

Multi-omics association study integrating GWAS and pQTL data revealed MIP-1α as a potential drug target for erectile dysfunction

in Pharmacogenetics and Pharmacogenomics

Jingwen Liu
Renbing Pan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1495970

469 views

Original Research

Published on 01 Nov 2024

Allele frequencies and genotype distribution of three metformin transporter polymorphisms in Mexican population and their application in pharmacogenomics of type 2 diabetes

in Pharmacogenetics and Pharmacogenomics

Oscar I. Chávez-Arreola
Brissia Lazalde
Marisol López-López
Alberto Ortega-Vázquez
Quitzia L. Torres-Salazar

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1466394

351 views

Review

Accepted on 30 Oct 2024

Pharmacogenomics For Neurodegenerative Disorders -A Focused Review

in Pharmacogenetics and Pharmacogenomics

S Rehan Ahmad
Md. Zeyaullah
Mohammad Suhail Khan
Dr Abdullah Alshahrani
Abdelrhman A Galaleldin Altijani
Haroon Ali
Adam Dawria
Ali Mohieldin
Mohammad Shane Alam
Awad Osman Abdalla Mohamed

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1478964

Original Research

Published on 30 Oct 2024

The role of candidate pharmacogenetic variants in determining valproic acid efficacy, toxicity and concentrations in patients with epilepsy

in Pharmacogenetics and Pharmacogenomics

Hady Yazbeck
Joe Youssef
Wassim Nasreddine
Abdullah El Kurdi
Nathalie Zgheib
Ahmad Beydoun

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1483723

355 views

Original Research

Published on 25 Oct 2024

A mathematical model of glomerular fibrosis in diabetic kidney disease to predict therapeutic efficacy

in Pharmacogenetics and Pharmacogenomics

Haryana Y. Thomas
Ashlee N. Ford Versypt

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1481768

402 views

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Articles

Clinical implications of a gain of function genetic polymorphism in DPYD (rs4294451) in colorectal cancer patients treated with fluoropyrimidines

Advancements in Precision Medicine: Multi-omics Approach for Tailored Metformin Treatment in Type 2 Diabetes

Metabolic pathways, genomic alterations, and post-translational modifications in pulmonary hypertension and cancer as therapeutic targets and biomarkers

Pediatric Flecainide Pharmacogenomics: A Roadmap to Deliver Precision Based Care to Pediatrics Arrhythmias

Investigation on regulation of N-acetyltransferase 2 expression by nuclear receptors in human hepatocytes

Population pharmacokinetic study of the effect of polymorphisms in the ABCB1 and CES1 genes on the pharmacokinetics of dabigatran

Novel genomic variants influencing methotrexate delayed clearance in pediatric patients with acute lymphoblastic leukemia

Integration of pharmacogenetic data in Epic Genomic Module drives best practice alerts

Tumor microenvironment and cancer metastasis: molecular mechanisms and therapeutic implications

Paromomycin targets HDAC1-mediated SUMOylation and IGF1R translocation in glioblastoma

Comparing Commercial Pharmacogenetic Testing Results and Recommendations for Antidepressants with Established CPIC Guidelines

Multi-omics association study integrating GWAS and pQTL data revealed MIP-1α as a potential drug target for erectile dysfunction

Allele frequencies and genotype distribution of three metformin transporter polymorphisms in Mexican population and their application in pharmacogenomics of type 2 diabetes

Pharmacogenomics For Neurodegenerative Disorders -A Focused Review

The role of candidate pharmacogenetic variants in determining valproic acid efficacy, toxicity and concentrations in patients with epilepsy

A mathematical model of glomerular fibrosis in diabetic kidney disease to predict therapeutic efficacy