Frontiers in Pharmacology | Pharmacogenetics and Pharmacogenomics

Perspective

Published on 22 Apr 2021

CYP2D6 Reduced Function Variants and Genotype/Phenotype Translations of CYP2D6 Intermediate Metabolizers: Implications for Personalized Drug Dosing in Psychiatry

in Pharmacogenetics and Pharmacogenomics

Espen Molden
Marin M. Jukić

Frontiers in Pharmacology

doi 10.3389/fphar.2021.650750

21,367 views
32 citations

Original Research

Published on 20 Apr 2021

CYP2D6 Genetic Variation and Its Implication for Vivax Malaria Treatment in Madagascar

in Pharmacogenetics and Pharmacogenomics

Rajeev K. Mehlotra
Andrea Gaedigk
Rosalind E. Howes
Tovonahary A. Rakotomanga
Arsene C. Ratsimbasoa
Peter A. Zimmerman

Frontiers in Pharmacology

doi 10.3389/fphar.2021.654054

4,946 views
8 citations

Original Research

Published on 16 Apr 2021

Clozapine Metabolism is Associated With Absolute Neutrophil Count in Individuals With Treatment-Resistant Schizophrenia

in Pharmacogenetics and Pharmacogenomics

Isabella R. Willcocks
Sophie E. Legge
Mariana Nalmpanti
Lucy Mazzeo
Adrian King
John Jansen
Marinka Helthuis
Michael J. Owen
Michael C. O’Donovan
James T. R. Walters

Frontiers in Pharmacology

doi 10.3389/fphar.2021.658734

9,768 views
18 citations

Brief Research Report

Published on 15 Apr 2021

Pharmacogenetics in Psychiatry: Perceived Value and Opinions in a Chilean Sample of Practitioners

in Pharmacogenetics and Pharmacogenomics

Juan Undurraga
Ignacio Bórquez-Infante
Nicolás A. Crossley
Miguel L. Prieto
Gabriela M. Repetto

Frontiers in Pharmacology

doi 10.3389/fphar.2021.657985

4,294 views
8 citations

Clinical Trial

Published on 15 Apr 2021

Multifocal Analysis of Acute Pain After Third Molar Removal

in Pharmacogenetics and Pharmacogenomics

Giovana Maria Weckwerth
Thiago José Dionísio
Yuri Martins Costa
Paulo Zupelari-Gonçalves
Gabriela Moraes Oliveira
Elza Araújo Torres
Leonardo Rigoldi Bonjardim
Flavio Augusto Cardoso Faria
Adriana Maria Calvo
Troy Moore

Frontiers in Pharmacology

doi 10.3389/fphar.2021.643874

4,639 views
9 citations

Brief Research Report

Published on 14 Apr 2021

Detection of EGFR Mutations From Plasma of NSCLC Patients Using an Automatic Cartridge-Based PCR System

in Pharmacogenetics and Pharmacogenomics

Simon Heeke
Véronique Hofman
Jonathan Benzaquen
Josiane Otto
Virginie Tanga
Katia Zahaf
Maryline Allegra
Elodie Long-Mira
Sandra Lassalle
Charles-Hugo Marquette

Frontiers in Pharmacology

doi 10.3389/fphar.2021.657743

4,608 views
17 citations

Original Research

Published on 13 Apr 2021

MGA Mutation as a Novel Biomarker for Immune Checkpoint Therapies in Non-Squamous Non-Small Cell Lung Cancer

in Pharmacogenetics and Pharmacogenomics

Lei Sun
Man Li
Ling Deng
Yuchun Niu
Yichun Tang
Yu Wang
Linlang Guo

Frontiers in Pharmacology

doi 10.3389/fphar.2021.625593

6,479 views
14 citations

Review

Published on 12 Apr 2021

Policy and Practice Review: A First Guideline on the Use of Pharmacogenetics in Clinical Psychiatric Practice

in Pharmacogenetics and Pharmacogenomics

R. van Westrhenen
R. H. N. van Schaik
T. van Gelder
T. K. Birkenhager
P. R. Bakker
E. J. F. Houwink
P. M. Bet
W. J. G. Hoogendijk
M. J. M. van Weelden-Hulshof

Frontiers in Pharmacology

doi 10.3389/fphar.2021.640032

9,887 views
36 citations

Original Research

Published on 12 Apr 2021

A New Insight for the Identification of Oncogenic Variants in Breast and Prostate Cancers in Diverse Human Populations, With a Focus on Latinos

in Pharmacogenetics and Pharmacogenomics

Nelson M. Varela
Patricia Guevara-Ramírez
Cristian Acevedo
Tomás Zambrano
Isaac Armendáriz-Castillo
Santiago Guerrero
Luis A. Quiñones
Andrés López-Cortés

Frontiers in Pharmacology

doi 10.3389/fphar.2021.630658

5,561 views
8 citations

Review

Published on 25 Mar 2021

The Genetics of Response to and Side Effects of Lithium Treatment in Bipolar Disorder: Future Research Perspectives

in Pharmacogenetics and Pharmacogenomics

Fanny Senner
Mojtaba Oraki Kohshour
Safa Abdalla
Sergi Papiol
Thomas G. Schulze

Frontiers in Pharmacology

doi 10.3389/fphar.2021.638882

13,265 views
28 citations

Opinion

Published on 19 Mar 2021

The Urgent Need for Management of Biological Samples and Data Accessibility in Latin America

in Pharmacogenetics and Pharmacogenomics

Rodrigo José Vargas
Oscar M. Cobar

Frontiers in Pharmacology

doi 10.3389/fphar.2021.620043

2,954 views
6 citations

Technology and Code

Published on 18 Mar 2021

Sequence2Script: A Web-Based Tool for Translation of Pharmacogenetic Data Into Evidence-Based Prescribing Recommendations

in Pharmacogenetics and Pharmacogenomics

Chad A. Bousman
Patrick Wu
Katherine J. Aitchison
Tony Cheng

Frontiers in Pharmacology

doi 10.3389/fphar.2021.636650

9,459 views
34 citations

Review

Published on 15 Mar 2021

G6PD Variants and Haemolytic Sensitivity to Primaquine and Other Drugs

in Pharmacogenetics and Pharmacogenomics

Germana Bancone
Cindy S. Chu

Frontiers in Pharmacology

doi 10.3389/fphar.2021.638885

20,116 views
43 citations

Original Research

Published on 10 Mar 2021

Pharmacogenetics–Based Preliminary Algorithm to Predict the Incidence of Infection in Patients Receiving Cytotoxic Chemotherapy for Hematological Malignancies: A Discovery Cohort

in Pharmacogenetics and Pharmacogenomics

Matias F. Martinez
Enzo Alveal
Tomas G. Soto
Eva I. Bustamante
Fernanda Ávila
Shrikant I. Bangdiwala
Ivonne Flores
Claudia Monterrosa
Ricardo Morales
Nelson M. Varela

Frontiers in Pharmacology

doi 10.3389/fphar.2021.602676

3,974 views
6 citations

Systematic Review

Published on 08 Mar 2021

Meta-Analysis of ABCG2 and ABCB1 Polymorphisms With Sunitinib-Induced Toxicity and Efficacy in Renal Cell Carcinoma

in Pharmacogenetics and Pharmacogenomics

Fengjun Sun
Zhuo Chen
Pu Yao
Bangbi Weng
Zhirui Liu
Lin Cheng

Frontiers in Pharmacology

doi 10.3389/fphar.2021.641075

4,116 views
16 citations

Original Research

Published on 08 Mar 2021

Cinical, Metabolic, and Genetic Analysis and Follow-Up of Eight Patients With HIBCH Mutations Presenting With Leigh/Leigh-Like Syndrome

in Pharmacogenetics and Pharmacogenomics

Junling Wang
Zhimei Liu
Manting Xu
Xiaodi Han
Changhong Ren
Xinying Yang
Chunhua Zhang
Fang Fang

Frontiers in Pharmacology

doi 10.3389/fphar.2021.605803

7,813 views
18 citations

Original Research

Published on 25 Feb 2021

Common Endothelial Nitric Oxide Synthase Single Nucleotide Polymorphisms are not Related With the Risk for Restless Legs Syndrome

in Pharmacogenetics and Pharmacogenomics

Félix Javier Jiménez-Jiménez
Blanca G. Agúndez
Javier Gómez-Tabales
Hortensia Alonso-Navarro
Laura Turpín-Fenoll
Jorge Millán-Pascual
Mónica Díez-Fairén
Ignacio Álvarez
Pau Pastor
Marisol Calleja

Frontiers in Pharmacology

doi 10.3389/fphar.2021.618989

3,414 views
4 citations

Original Research

Published on 24 Feb 2021

The NTCP p.Ser267Phe Variant Is Associated With a Faster Anti-HBV Effect on First-Line Nucleos(t)ide Analog Treatment

in Pharmacogenetics and Pharmacogenomics

Lina Wu
Wenxiong Xu
Xuejun Li
Ying Liu
Lu Wang
Shu Zhu
Fangji Yang
Chan Xie
Liang Peng

Frontiers in Pharmacology

doi 10.3389/fphar.2021.616858

3,164 views
10 citations

General Commentary

Published on 23 Feb 2021

Commentary: The Clinical Impact of the C0/D Ratio and the CYP3A5 Genotype on Outcome in Tacrolimus Treated Kidney Transplant Recipients

in Pharmacogenetics and Pharmacogenomics

Gerold Thölking
Stefan Reuter

Frontiers in Pharmacology

doi 10.3389/fphar.2021.603345

2,328 views
2 citations

Original Research

Published on 16 Feb 2021

Obesity Connected Metabolic Changes in Type 2 Diabetic Patients Treated With Metformin

in Pharmacogenetics and Pharmacogenomics

Shereen M. Aleidi
Lina A. Dahabiyeh
Xinyun Gu
Mohammed Al Dubayee
Awad Alshahrani
Hicham Benabdelkamel
Muhammad Mujammami
Liang Li
Ahmad Aljada
Anas M. Abdel Rahman

Frontiers in Pharmacology

doi 10.3389/fphar.2020.616157

7,445 views
33 citations

Original Research

Published on 11 Feb 2021

Identification and Enzymatic Activity Evaluation of a Novel CYP2C9 Allelic Variant Discovered in a Patient

in Pharmacogenetics and Pharmacogenomics

Xiao-Yang Zhou
Xiang-Ran Lu
Ying-Hui Li
Ya-Qing Ma
Shi-Wen Zhao
Fang Wang
Ren-Ai Xu
Guo-Xin Hu
Jian-Ping Cai

Frontiers in Pharmacology

doi 10.3389/fphar.2021.619339

4,546 views
2 citations

Original Research

Published on 09 Feb 2021

Diffusion Mechanism Modeling of Metformin in Human Organic Cationic Amino Acid Transporter one and Functional Impact of S189L, R206C, and G401S Mutation

in Pharmacogenetics and Pharmacogenomics

Leydy Cano
Alejandro Soto-Ospina
Pedronel Araque
Maria Antonieta Caro-Gomez
Maria Victoria Parra-Marin
Gabriel Bedoya
Constanza Duque

Frontiers in Pharmacology

doi 10.3389/fphar.2020.587590

6,126 views
10 citations

Correction

Published on 08 Feb 2021

Corrigendum: COVIEdb: A Database for Potential Immune Epitopes of Coronaviruses

in Pharmacogenetics and Pharmacogenomics

Jingcheng Wu
Wenfan Chen
Jingjing Zhou
Wenyi Zhao
Yisheng Sun
Hanping Zhu
Pingping Yao
Shuqing Chen
Jianmin Jiang
Zhan Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2020.646111

1,702 views
1 citation

Original Research

Published on 02 Feb 2021

Genotype Analysis of ABCC1, NCF4 and CBR3 Polymorphism and the Association With Childhood Acute Lymphoblastic Leukemia in Mexican Childhood Population

in Pharmacogenetics and Pharmacogenomics

Jesús Alonso Gándara-Mireles
Ismael Lares-Asseff
Elio Aarón Reyes Espinoza
Javier G. Blanco
Isaias Chairez Hernández
Lourdes Patricia Córdova Hurtado
Verónica Loera Castañeda
Leslie Patrón Romero
Cristina Venzor Sánchez
Hugo Payan Gándara

Frontiers in Pharmacology

doi 10.3389/fphar.2020.616630

3,723 views
5 citations

656 articles

articles

CYP2D6 Reduced Function Variants and Genotype/Phenotype Translations of CYP2D6 Intermediate Metabolizers: Implications for Personalized Drug Dosing in Psychiatry

CYP2D6 Genetic Variation and Its Implication for Vivax Malaria Treatment in Madagascar

Clozapine Metabolism is Associated With Absolute Neutrophil Count in Individuals With Treatment-Resistant Schizophrenia

Pharmacogenetics in Psychiatry: Perceived Value and Opinions in a Chilean Sample of Practitioners

Multifocal Analysis of Acute Pain After Third Molar Removal

Detection of EGFR Mutations From Plasma of NSCLC Patients Using an Automatic Cartridge-Based PCR System

MGA Mutation as a Novel Biomarker for Immune Checkpoint Therapies in Non-Squamous Non-Small Cell Lung Cancer

Policy and Practice Review: A First Guideline on the Use of Pharmacogenetics in Clinical Psychiatric Practice

A New Insight for the Identification of Oncogenic Variants in Breast and Prostate Cancers in Diverse Human Populations, With a Focus on Latinos

The Genetics of Response to and Side Effects of Lithium Treatment in Bipolar Disorder: Future Research Perspectives

The Urgent Need for Management of Biological Samples and Data Accessibility in Latin America

Sequence2Script: A Web-Based Tool for Translation of Pharmacogenetic Data Into Evidence-Based Prescribing Recommendations

G6PD Variants and Haemolytic Sensitivity to Primaquine and Other Drugs

Pharmacogenetics–Based Preliminary Algorithm to Predict the Incidence of Infection in Patients Receiving Cytotoxic Chemotherapy for Hematological Malignancies: A Discovery Cohort

Meta-Analysis of ABCG2 and ABCB1 Polymorphisms With Sunitinib-Induced Toxicity and Efficacy in Renal Cell Carcinoma

Cinical, Metabolic, and Genetic Analysis and Follow-Up of Eight Patients With HIBCH Mutations Presenting With Leigh/Leigh-Like Syndrome

Common Endothelial Nitric Oxide Synthase Single Nucleotide Polymorphisms are not Related With the Risk for Restless Legs Syndrome

The NTCP p.Ser267Phe Variant Is Associated With a Faster Anti-HBV Effect on First-Line Nucleos(t)ide Analog Treatment

Commentary: The Clinical Impact of the C0/D Ratio and the CYP3A5 Genotype on Outcome in Tacrolimus Treated Kidney Transplant Recipients

Obesity Connected Metabolic Changes in Type 2 Diabetic Patients Treated With Metformin

Identification and Enzymatic Activity Evaluation of a Novel CYP2C9 Allelic Variant Discovered in a Patient

Diffusion Mechanism Modeling of Metformin in Human Organic Cationic Amino Acid Transporter one and Functional Impact of S189L, R206C, and G401S Mutation

Corrigendum: COVIEdb: A Database for Potential Immune Epitopes of Coronaviruses

Genotype Analysis of ABCC1, NCF4 and CBR3 Polymorphism and the Association With Childhood Acute Lymphoblastic Leukemia in Mexican Childhood Population