Frontiers in Pharmacology | Pharmacogenetics and Pharmacogenomics

Review

Published on 28 Jun 2021

Pharmacogenomics of Impaired Tyrosine Kinase Inhibitor Response: Lessons Learned From Chronic Myelogenous Leukemia

in Pharmacogenetics and Pharmacogenomics

Meike Kaehler
Ingolf Cascorbi

Frontiers in Pharmacology

doi 10.3389/fphar.2021.696960

5,472 views
29 citations

Original Research

Published on 28 Jun 2021

Pharmacogenomics Implementation Training Improves Self-Efficacy and Competency to Drive Adoption in Clinical Practice

in Pharmacogenetics and Pharmacogenomics

Fadhli Adesta
Caroline Mahendra
Kathleen Irena Junusmin
Arya Melissa Selva Rajah
Sharon Goh
Levana Sani
Alexandre Chan
Astrid Irwanto

Frontiers in Pharmacology

doi 10.3389/fphar.2021.684907

3,848 views
10 citations

Mini Review

Published on 21 Jun 2021

Pharmacogenomics of NSAID-Induced Upper Gastrointestinal Toxicity

in Pharmacogenetics and Pharmacogenomics

L. McEvoy
D. F. Carr
M. Pirmohamed

Frontiers in Pharmacology

doi 10.3389/fphar.2021.684162

25,057 views
53 citations

Brief Research Report

Published on 16 Jun 2021

ABCB1 and ABCG2 Together Limit the Distribution of ABCB1/ABCG2 Substrates to the Human Retina and the ABCG2 Single Nucleotide Polymorphism Q141K (c.421C> A) May Lead to Increased Drug Exposure

in Pharmacogenetics and Pharmacogenomics

Myriam El Biali
Rudolf Karch
Cécile Philippe
Helmuth Haslacher
Nicolas Tournier
Marcus Hacker
Markus Zeitlinger
Doreen Schmidl
Oliver Langer
Martin Bauer

Frontiers in Pharmacology

doi 10.3389/fphar.2021.698966

3,239 views
6 citations

Correction

Published on 10 Jun 2021

Corrigendum: Cinical, Metabolic, and Genetic Analysis and Follow-Up of Eight Patients With HIBCH Mutations Presenting With Leigh/Leigh-Like Syndrome

in Pharmacogenetics and Pharmacogenomics

Junling Wang
Zhimei Liu
Manting Xu
Xiaodi Han
Changhong Ren
Xinying Yang
Chunhua Zhang
Fang Fang

Frontiers in Pharmacology

doi 10.3389/fphar.2021.686933

1,377 views

Original Research

Published on 09 Jun 2021

Role of Common Genetic Variants for Drug-Resistance to Specific Anti-Seizure Medications

in Pharmacogenetics and Pharmacogenomics

Stefan Wolking
Ciarán Campbell
Caragh Stapleton
Mark McCormack
Norman Delanty
Chantal Depondt
Michael R. Johnson
Bobby P. C. Koeleman
Roland Krause
Wolfram S. Kunz

Frontiers in Pharmacology

doi 10.3389/fphar.2021.688386

7,551 views
13 citations

Review

Published on 09 Jun 2021

From Genome to Drugs: New Approaches in Antimicrobial Discovery

in Pharmacogenetics and Pharmacogenomics

Federico Serral
Florencia A. Castello
Ezequiel J. Sosa
Agustín M. Pardo
Miranda Clara Palumbo
Carlos Modenutti
María Mercedes Palomino
Alberto Lazarowski
Jerónimo Auzmendi
Pablo Ivan P. Ramos

Frontiers in Pharmacology

doi 10.3389/fphar.2021.647060

12,568 views
34 citations

Original Research

Published on 07 Jun 2021

Comparative Analysis for the Performance of Long-Read-Based Structural Variation Detection Pipelines in Tandem Repeat Regions

in Pharmacogenetics and Pharmacogenomics

Mingkun Guo
Shihai Li
Yifan Zhou
Menglong Li
Zhining Wen

Frontiers in Pharmacology

doi 10.3389/fphar.2021.658072

2,820 views
3 citations

Original Research

Published on 03 Jun 2021

Theragnosis for Duchenne Muscular Dystrophy

in Pharmacogenetics and Pharmacogenomics

Leonela Luce
Micaela Carcione
Chiara Mazzanti
Paula I. Buonfiglio
Viviana Dalamón
Lilia Mesa
Alberto Dubrovsky
José Corderí
Florencia Giliberto

Frontiers in Pharmacology

doi 10.3389/fphar.2021.648390

5,561 views
6 citations

Case Report

Published on 28 May 2021

Case Report of Novel Genetic Variant in KCNT1 Channel and Pharmacological Treatment With Quinidine. Precision Medicine in Refractory Epilepsy

in Pharmacogenetics and Pharmacogenomics

M. C. Kravetz
M. S. Viola
J. Prenz
M. Curi
G. F. Bramuglia
S. Tenembaum

Frontiers in Pharmacology

doi 10.3389/fphar.2021.648519

4,373 views
6 citations

Original Research

Published on 26 May 2021

HLA Risk Alleles in Aromatic Antiepileptic Drug-Induced Maculopapular Exanthema

in Pharmacogenetics and Pharmacogenomics

Yi-Wu Shi
Jie Wang
Fu-Li Min
Wen-Jun Bian
Bi-Jun Mao
Yong Mao
Bing Qin
Bing-Mei Li
Yang-Mei Ou
Yun-Qi Hou

Frontiers in Pharmacology

doi 10.3389/fphar.2021.671572

5,542 views
10 citations

Original Research

Published on 21 May 2021

Effects of Genetic Polymorphism in CYP2D6, CYP2C19, and the Organic Cation Transporter OCT1 on Amitriptyline Pharmacokinetics in Healthy Volunteers and Depressive Disorder Patients

in Pharmacogenetics and Pharmacogenomics

Johannes Matthaei
Jürgen Brockmöller
Werner Steimer
Konstanze Pischa
Stefan Leucht
Maria Kullmann
Ole Jensen
Typhaine Ouethy
Mladen Vassilev Tzvetkov
Muhammad Rafehi

Frontiers in Pharmacology

doi 10.3389/fphar.2021.688950

8,542 views
19 citations

Original Research

Published on 21 May 2021

MicroRNA-33b is a Potential Non-Invasive Biomarker for Response to Atorvastatin Treatment in Chilean Subjects With Hypercholesterolemia: A Pilot Study

in Pharmacogenetics and Pharmacogenomics

Carmen Gloria Ubilla
Yalena Prado
Jeremy Angulo
Ignacio Obreque
Isis Paez
Nicolás Saavedra
Kathleen Saavedra
Tomás Zambrano
Luis A. Salazar

Frontiers in Pharmacology

doi 10.3389/fphar.2021.674252

2,605 views
6 citations

Original Research

Published on 19 May 2021

Pharmacogenetic Associations Between Atazanavir/UGT1A1*28 and Efavirenz/rs3745274 (CYP2B6) Account for Specific Adverse Reactions in Chilean Patients Undergoing Antiretroviral Therapy

in Pharmacogenetics and Pharmacogenomics

Daniela Poblete
Fernando Bernal
Gabriel Llull
Sebastian Archiles
Patricia Vasquez
Leonardo Chanqueo
Nicole Soto
María A. Lavanderos
Luis A. Quiñones
Nelson M. Varela

Frontiers in Pharmacology

doi 10.3389/fphar.2021.660965

4,674 views
6 citations

Original Research

Published on 18 May 2021

Association Between Genetic Polymorphisms of Metabolic Enzymes and Azathioprine-Induced Myelosuppression in 1,419 Chinese Patients: A Retrospective Study

in Pharmacogenetics and Pharmacogenomics

Zhao-Yang Chen
Yang-Hui Zhu
Ling-Yan Zhou
Wei-Qiao Shi
Zhou Qin
Bin Wu
Yu Yan
Yu-Wen Pei
Ning-Ning Chao
Rui Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2021.672769

4,606 views
16 citations

Original Research

Published on 07 May 2021

CYP2D6 in the Brain: Potential Impact on Adverse Drug Reactions in the Central Nervous System—Results From the ADRED Study

in Pharmacogenetics and Pharmacogenomics

Katja S. Just
Harald Dormann
Mathias Freitag
Marlen Schurig
Miriam Böhme
Michael Steffens
Catharina Scholl
Thomas Seufferlein
Ingo Graeff
Matthias Schwab

Frontiers in Pharmacology

doi 10.3389/fphar.2021.624104

16,129 views
14 citations

Navigation group

Articles

Pharmacogenomics of Impaired Tyrosine Kinase Inhibitor Response: Lessons Learned From Chronic Myelogenous Leukemia

Pharmacogenomics Implementation Training Improves Self-Efficacy and Competency to Drive Adoption in Clinical Practice

Pharmacogenomics of NSAID-Induced Upper Gastrointestinal Toxicity

ABCB1 and ABCG2 Together Limit the Distribution of ABCB1/ABCG2 Substrates to the Human Retina and the ABCG2 Single Nucleotide Polymorphism Q141K (c.421C> A) May Lead to Increased Drug Exposure

Corrigendum: Cinical, Metabolic, and Genetic Analysis and Follow-Up of Eight Patients With HIBCH Mutations Presenting With Leigh/Leigh-Like Syndrome

Role of Common Genetic Variants for Drug-Resistance to Specific Anti-Seizure Medications

From Genome to Drugs: New Approaches in Antimicrobial Discovery

Comparative Analysis for the Performance of Long-Read-Based Structural Variation Detection Pipelines in Tandem Repeat Regions

Theragnosis for Duchenne Muscular Dystrophy

Case Report of Novel Genetic Variant in KCNT1 Channel and Pharmacological Treatment With Quinidine. Precision Medicine in Refractory Epilepsy

HLA Risk Alleles in Aromatic Antiepileptic Drug-Induced Maculopapular Exanthema

Effects of Genetic Polymorphism in CYP2D6, CYP2C19, and the Organic Cation Transporter OCT1 on Amitriptyline Pharmacokinetics in Healthy Volunteers and Depressive Disorder Patients

MicroRNA-33b is a Potential Non-Invasive Biomarker for Response to Atorvastatin Treatment in Chilean Subjects With Hypercholesterolemia: A Pilot Study

Pharmacogenetic Associations Between Atazanavir/UGT1A1*28 and Efavirenz/rs3745274 (CYP2B6) Account for Specific Adverse Reactions in Chilean Patients Undergoing Antiretroviral Therapy

Association Between Genetic Polymorphisms of Metabolic Enzymes and Azathioprine-Induced Myelosuppression in 1,419 Chinese Patients: A Retrospective Study

CYP2D6 in the Brain: Potential Impact on Adverse Drug Reactions in the Central Nervous System—Results From the ADRED Study