Frontiers in Pharmacology | Pharmacogenetics and Pharmacogenomics

Original Research

Published on 21 Sep 2021

Lack of Major Involvement of Common CYP2C Gene Polymorphisms in the Risk of Developing Cross-Hypersensitivity to NSAIDs

in Pharmacogenetics and Pharmacogenomics

Yolanda Macías
Jesús M. García-Menaya
Manuel Martí
Concepción Cordobés
Raquel Jurado-Escobar
José A. Cornejo-García
María J. Torres
Natalia Blanca-López
Gabriela Canto
Miguel Blanca

Frontiers in Pharmacology

doi 10.3389/fphar.2021.648262

3,870 views
3 citations

Perspective

Published on 17 Sep 2021

Adoption of Pharmacogenomic Testing: A Marketing Perspective

in Pharmacogenetics and Pharmacogenomics

Margarita-Ioanna Koufaki
Kariofyllis Karamperis
Polixeni Vitsa
Konstantinos Vasileiou
George P. Patrinos
Christina Mitropoulou

Frontiers in Pharmacology

doi 10.3389/fphar.2021.724311

6,376 views
11 citations

Original Research

Published on 17 Sep 2021

Multi-Omics Approach to Dissect the Mechanisms of Rexinoid Signaling in Myoblast Differentiation

in Pharmacogenetics and Pharmacogenomics

Saadia Khilji
Yuan Li
Jihong Chen
Qiao Li

Frontiers in Pharmacology

doi 10.3389/fphar.2021.746513

2,912 views
4 citations

Original Research

Published on 16 Sep 2021

Non-Coding RNA Polymorphisms (rs2910164 and rs1333049) Associated With Prognosis of Lung Cancer Under Platinum-Based Chemotherapy

in Pharmacogenetics and Pharmacogenomics

Yi-Xin Chen
Juan Chen
Ji-Ye Yin
Hong-Hao Zhou
Bai-Mei He
Zhao-Qian Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2021.709528

2,287 views
7 citations

Original Research

Published on 14 Sep 2021

Organic Anion Transporting Polypeptide 2B1 (OATP2B1) Genetic Variants: In Vitro Functional Characterization and Association With Circulating Concentrations of Endogenous Substrates

in Pharmacogenetics and Pharmacogenomics

Samantha Medwid
Hayley R. Price
Daniel P. Taylor
Jaymie Mailloux
Ute I. Schwarz
Richard B. Kim
Rommel G. Tirona

Frontiers in Pharmacology

doi 10.3389/fphar.2021.713567

6,367 views
19 citations

Original Research

Published on 13 Sep 2021

CircRNA Microarray Profiling Reveals hsa_circ_0058493 as a Novel Biomarker for Imatinib-Resistant CML

in Pharmacogenetics and Pharmacogenomics

An-Ni Zhong
Yi Yin
Bing-Jie Tang
Lei Chen
Hong-Wei Shen
Zhi-Ping Tan
Wen-Qun Li
Qun He
Bao Sun
Yan Zhu

Frontiers in Pharmacology

doi 10.3389/fphar.2021.728916

4,844 views
23 citations

Original Research

Published on 02 Sep 2021

Targeting of Protein’s Messenger RNA for Viral Replication, Assembly and Release in SARS-CoV-2 Using Whole Genomic Data From South Africa: Therapeutic Potentials of Cannabis Sativa L

in Pharmacogenetics and Pharmacogenomics

Ochuko L. Erukainure
Motlalepula G. Matsabisa
Aliyu Muhammad
Musa M. Abarshi
James F. Amaku
Sanusi B. Katsayal
Adeline Lum Nde

Frontiers in Pharmacology

doi 10.3389/fphar.2021.736511

5,261 views
7 citations

Original Research

Published on 31 Aug 2021

Effect of Pharmacogenetics Variations on Praziquantel Plasma Concentrations and Schistosomiasis Treatment Outcomes Among Infected School-Aged Children in Tanzania

in Pharmacogenetics and Pharmacogenomics

Rajabu Hussein Mnkugwe
Omary Minzi
Safari Kinung’hi
Appolinary Kamuhabwa
Eleni Aklillu

Frontiers in Pharmacology

doi 10.3389/fphar.2021.712084

2,839 views
13 citations

Review

Published on 30 Aug 2021

A Review of CYP3A Drug-Drug Interaction Studies: Practical Guidelines for Patients Using Targeted Oral Anticancer Drugs

in Pharmacogenetics and Pharmacogenomics

Laura Molenaar-Kuijsten
Dorieke E. M. Van Balen
Jos H. Beijnen
Neeltje Steeghs
Alwin D. R. Huitema

Frontiers in Pharmacology

doi 10.3389/fphar.2021.670862

16,411 views
28 citations

Original Research

Published on 27 Aug 2021

CYP2C19 Genotyping May Provide a Better Treatment Strategy when Administering Escitalopram in Chinese Population

in Pharmacogenetics and Pharmacogenomics

Xinyi Huang
Chao Li
Chaopeng Li
Zhenyu Li
Xiaohui Li
Jianwei Liao
Tai Rao
Lulu Chen
Lichen Gao
Dongsheng Ouyang

Frontiers in Pharmacology

doi 10.3389/fphar.2021.730461

6,783 views
10 citations

Original Research

Published on 26 Aug 2021

CYP450 Genotype—Phenotype Concordance Using the Geneva Micrococktail in a Clinical Setting

in Pharmacogenetics and Pharmacogenomics

Kuntheavy Ing Lorenzini
Jules Desmeules
Victoria Rollason
Stéphane Bertin
Marie Besson
Youssef Daali
Caroline F. Samer

Frontiers in Pharmacology

doi 10.3389/fphar.2021.730637

6,513 views
19 citations

Review

Published on 25 Aug 2021

Applying Next-Generation Sequencing Platforms for Pharmacogenomic Testing in Clinical Practice

in Pharmacogenetics and Pharmacogenomics

Alireza Tafazoli
Henk-Jan Guchelaar
Wojciech Miltyk
Adam J. Kretowski
Jesse J. Swen

Frontiers in Pharmacology

doi 10.3389/fphar.2021.693453

17,556 views
44 citations

Original Research

Published on 18 Aug 2021

Predicting Drug-Induced Liver Injury Using Machine Learning on a Diverse Set of Predictors

in Pharmacogenetics and Pharmacogenomics

Temidayo Adeluwa
Brett A. McGregor
Kai Guo
Junguk Hur

Frontiers in Pharmacology

doi 10.3389/fphar.2021.648805

7,195 views
16 citations

Original Research

Published on 13 Aug 2021

Identification of EP300 as a Key Gene Involved in Antipsychotic-Induced Metabolic Dysregulation Based on Integrative Bioinformatics Analysis of Multi-Tissue Gene Expression Data

in Pharmacogenetics and Pharmacogenomics

Albert Martínez-Pinteño
Patricia Gassó
Llucia Prohens
Alex G. Segura
Mara Parellada
Jerónimo Saiz-Ruiz
Manuel J. Cuesta
Miguel Bernardo
Amalia Lafuente
Sergi Mas

Frontiers in Pharmacology

doi 10.3389/fphar.2021.729474

6,019 views
3 citations

Original Research

Published on 26 Jul 2021

Validation of Single Nucleotide Variant Assays for Human Leukocyte Antigen Haplotypes HLA-B15:02 and HLA-A31:01 Across Diverse Ancestral Backgrounds

in Pharmacogenetics and Pharmacogenomics

Amanda Buchner
Xiuying Hu
Katherine J. Aitchison

Frontiers in Pharmacology

doi 10.3389/fphar.2021.713178

6,120 views
3 citations

Brief Research Report

Published on 23 Jul 2021

CYP2D6 Allele Frequency in Five Malaria Vivax Endemic Areas From Brazilian Amazon Region

in Pharmacogenetics and Pharmacogenomics

Paula Ferreira Salles
Daiana Souza Perce-da-Silva
Atila Duque Rossi
Luisa Riehl Raposo
Aina Danaisa Ramirez Ramirez
Otílio Machado Pereira Bastos
Lilian Rose Pratt-Riccio
Gustavo Capatti Cassiano
Andrea Regina Souza Baptista
Cynthia Chester Cardoso

Frontiers in Pharmacology

doi 10.3389/fphar.2021.542342

3,044 views
3 citations

Lack of Major Involvement of Common CYP2C Gene Polymorphisms in the Risk of Developing Cross-Hypersensitivity to NSAIDs

Adoption of Pharmacogenomic Testing: A Marketing Perspective

Multi-Omics Approach to Dissect the Mechanisms of Rexinoid Signaling in Myoblast Differentiation

Non-Coding RNA Polymorphisms (rs2910164 and rs1333049) Associated With Prognosis of Lung Cancer Under Platinum-Based Chemotherapy

Organic Anion Transporting Polypeptide 2B1 (OATP2B1) Genetic Variants: In Vitro Functional Characterization and Association With Circulating Concentrations of Endogenous Substrates

CircRNA Microarray Profiling Reveals hsa_circ_0058493 as a Novel Biomarker for Imatinib-Resistant CML

Targeting of Protein’s Messenger RNA for Viral Replication, Assembly and Release in SARS-CoV-2 Using Whole Genomic Data From South Africa: Therapeutic Potentials of Cannabis Sativa L

Effect of Pharmacogenetics Variations on Praziquantel Plasma Concentrations and Schistosomiasis Treatment Outcomes Among Infected School-Aged Children in Tanzania

A Review of CYP3A Drug-Drug Interaction Studies: Practical Guidelines for Patients Using Targeted Oral Anticancer Drugs

CYP2C19 Genotyping May Provide a Better Treatment Strategy when Administering Escitalopram in Chinese Population

CYP450 Genotype—Phenotype Concordance Using the Geneva Micrococktail in a Clinical Setting

Applying Next-Generation Sequencing Platforms for Pharmacogenomic Testing in Clinical Practice

Predicting Drug-Induced Liver Injury Using Machine Learning on a Diverse Set of Predictors

Identification of EP300 as a Key Gene Involved in Antipsychotic-Induced Metabolic Dysregulation Based on Integrative Bioinformatics Analysis of Multi-Tissue Gene Expression Data

Validation of Single Nucleotide Variant Assays for Human Leukocyte Antigen Haplotypes HLA-B*15:02 and HLA-A*31:01 Across Diverse Ancestral Backgrounds

CYP2D6 Allele Frequency in Five Malaria Vivax Endemic Areas From Brazilian Amazon Region

Validation of Single Nucleotide Variant Assays for Human Leukocyte Antigen Haplotypes HLA-B15:02 and HLA-A31:01 Across Diverse Ancestral Backgrounds