Frontiers in Pharmacology | Pharmacogenetics and Pharmacogenomics

Review

Published on 07 Aug 2025

Global variation in antibiotic prescribing guidelines and the implications for decreasing AMR in the future

in Pharmacogenetics and Pharmacogenomics

Emmama Jamil
Zikria Saleem
Brian Godman
Matti Ullah
Afreenish Amir
Abdul Haseeb
Johanna C. Meyer
Muhammad Usman Qamar
Safa S. Almarzoky Abuhussain

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1600787

6,477 views
9 citations

Clinical Trial

Published on 07 Aug 2025

Clinicians’ experience on the effectiveness of pharmacotherapy in patients with first-episode depression: a randomized controlled trial based on pharmacogenomics

in Pharmacogenetics and Pharmacogenomics

Jie Tong
Jie Yuan
Yu Qin
Na Zhu
Tingting Zhang
Xiaochun Zhu
Yuanyuan Xu
Meilin Liu
Jie Zhang
Xirong Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1626654

1,878 views

Review

Published on 07 Aug 2025

The role and challenges of intratumoral microbiota in colorectal cancer immunotherapy

in Pharmacogenetics and Pharmacogenomics

Miao Hao
Haiming Xu
Min Li
Dan Jiao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1634703

3,024 views
2 citations

Original Research

Published on 21 Jul 2025

Clinical significance and gene prediction of a novel classification system based on tacrolimus concentration-to-dose ratio in the early post-liver transplant period

in Pharmacogenetics and Pharmacogenomics

Junwei Fan
Peihao Wen
Liyun Yuan
Yan Xia
Shijie Hu
Xiaoqing Zhang
Zhihai Peng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1614753

2,129 views

Mini Review

Published on 17 Jul 2025

Statins and their impact on epigenetic regulation: insights into disease

in Pharmacogenetics and Pharmacogenomics

Rafael Tamayo-Trujillo
Patricia Guevara-Ramírez
Santiago Cadena-Ullauri
Viviana A. Ruiz Pozo
Elius Paz-Cruz
Ana Karina Zambrano

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1621163

3,501 views
3 citations

Systematic Review

Published on 16 Jul 2025

Polymorphisms in CYP3A5, CYP3A4, and ABCB1 genes: implications for calcineurin inhibitors therapy in hematopoietic cell transplantation recipients—a systematic review

in Pharmacogenetics and Pharmacogenomics

Luiz Carlos da Costa-Junior
Daniely Regina Freitas-Alves
Amanda Melo Leite Leão
Hayra de Andrade Vieira Monteiro
Rita de Cássia Barbosa da Silva Tavares
Maria Claudia Rodrigues Moreira
Marília Berlofa Visacri
Teresa de Souza Fernandez
Paulo Caleb Júnior de Lima Santos

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1569353

2,763 views
2 citations

Review

Published on 16 Jul 2025

Epigenetic modifications of gut microbiota and their potential role in atherosclerosis

in Pharmacogenetics and Pharmacogenomics

Shuang Guo
Junlai Zhao
Rongrong Zhu
Zhi Fan
Shibiao Liu
Weiwei Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1638240

2,889 views

Systematic Review

Published on 16 Jul 2025

Clinical and cost-effectiveness of pharmacogenomic testing for anthracycline-induced cardiotoxicity in childhood cancer: a systematic review and meta-analysis

in Pharmacogenetics and Pharmacogenomics

Ling Yin Fritz Wong
Alastair G. Sutcliffe
Carmen Lok Tung Ho
Yan Lu
Carrie L. Williams
Faiza Afzal
Mitana Purkayastha

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1568320

4,179 views
1 citation

Editorial

Published on 15 Jul 2025

Editorial: Editor’s feature: negative findings in pharmacogenetics and pharmacogenomics volume II

in Pharmacogenetics and Pharmacogenomics

José A. G. Agúndez
Elena García-Martín
Luis Abel Quiñones

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1658876

1,321 views

Editorial

Published on 07 Jul 2025

Editorial: Post-translational modifications in human cancer: pharmacological insights and therapeutic opportunities

in Pharmacogenetics and Pharmacogenomics

Yongzhi Chen
Angelina W. Fan
Lei Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1654659

2,094 views
4 citations

Original Research

Published on 04 Jul 2025

Exploring biomarkers for noise-induced hearing loss through mitochondrial DNA methylation analysis

in Pharmacogenetics and Pharmacogenomics

Dianpeng Wang
Caiping Li
Liuwei Shi
Dafeng Lin
Shaofan Weng
Xiangli Yang
Peimao Li
Zhimin Zhang
Wen Zhang
Yan Guo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1561791

2,882 views

Editorial

Published on 01 Jul 2025

Editorial: Pharmacogenomics for improving drug safety and efficacy in cancer

in Pharmacogenetics and Pharmacogenomics

Zhiyao He
Xuewei Fu
Zhijie Xu
Omar Alshargi
Roberto Rodríguez-Labrada
Xiao-Bo Zhong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1649258

3,366 views
2 citations

Systematic Review

Published on 19 Jun 2025

CYP2C19 variability and clinical outcomes of clopidogrel, proton pump inhibitors, and voriconazole in Southeast Asia: a systematic review and meta-analysis

in Pharmacogenetics and Pharmacogenomics

Harri Hardi
Agian Jeffilano Barinda
Liganda Endo Mahata
Zahra Fitrianti

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1572886

5,241 views
5 citations

Original Research

Published on 13 Jun 2025

Hsa_circ_0002238 promotes the malignant behavior of colorectal cancer

in Pharmacogenetics and Pharmacogenomics

Lin-Ting Zhang
Yuejia Zhou
Tiantian Wang
Boran Chen
Zhigao Cai
Shubin Wang
Gangling Tong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1541820

1,936 views
1 citation

Original Research

Published on 04 Jun 2025

Genetic polymorphisms as predictors of the response of hepatocellular carcinoma patients to doxorubicin chemotherapy: a genome-wide association study

in Pharmacogenetics and Pharmacogenomics

Sireen Abdul Rahim Shilbayeh
Naglaa F. Khedr
Mohammad A. Alshabeeb
Abdulmonem Ali Alsaleh
Abdalrhman Hamdan Alanizi
Omnia A. Abd El-Baset
Rehab H. Werida

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1604473

3,283 views
1 citation

Original Research

Published on 03 Jun 2025

Exosomal miR-24-3p mediates myoblast-macrophage crosstalk to promote abdominal muscle repair

in Pharmacogenetics and Pharmacogenomics

Yuchen Liu
Zhenyu Zou
Jinxin Cao
Tong Zhu
Yilin Zhu
Yingmo Shen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1604776

2,044 views

Brief Research Report

Published on 23 May 2025

Dynamic star allele definitions in Pharmacogenomics: impact on diplotype calls, Phenotype predictions and statin therapy recommendations

in Pharmacogenetics and Pharmacogenomics

Sven van der Maas
Simon Denil
Brigitte Maes
Gökhan Ertaylan
Pieter-Jan Volders

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1584658

2,835 views
2 citations

Original Research

Published on 22 May 2025

Biological and prognostic insights into the prostaglandin D2 signaling axis in lung adenocarcinoma

in Pharmacogenetics and Pharmacogenomics

Qiang Liu
Huiguo Chen
Dongfang Tang
Huibiao Zhang
Shaogeng Chen
Yiran Meng
Boying Zheng
Fei Liu
Jing Zhou
Wen Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1562261

5,739 views
1 citation

Brief Research Report

Published on 22 May 2025

Implementation and integration of a multidisciplinary pharmacogenomics service in an underserved integrated behavioral health clinic

in Pharmacogenetics and Pharmacogenomics

Bader M. Alghamdi
Sara Rogers
Susan Roberman
Meredith Williamson
Ladan Panahi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1594032

2,599 views
1 citation

Case Report

Published on 21 May 2025

The role of endoplasmic reticulum aminopeptidase ERAP2 pathogenic mutation rs1363907 in amoxicillin clavulanate-induced liver injury: a special case report

in Pharmacogenetics and Pharmacogenomics

Yan Zhan
Jin-Mao Liao
Ling Ye
Long Zhang
Zheng Zhang
Ji-Ye Yin

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1564124

2,134 views
2 citations

Original Research

Published on 20 May 2025

ARID1A deficiency attenuates the response to EGFR-TKI treatment in lung adenocarcinoma

in Pharmacogenetics and Pharmacogenomics

Fangfang Yang
Helei Hou
Guanqun Wang
Guangming Fu
Xingfa Huo
Xueqin Duan
Na Zhou
Xiaochun Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1582005

2,859 views
1 citation

Original Research

Published on 13 May 2025

Impact of CYP3A5 1* and 3* single nucleotide variants on tacrolimus pharmacokinetics and graft rejection risk in pediatric kidney transplant patients

in Pharmacogenetics and Pharmacogenomics

Lesly Yanira Xajil-Ramos
Jesús Alonso Gándara-Mireles
Rodrigo José Vargas Rosales
Oscar Kevin Sánchez García
Andrea Mariela Ruano Toledo
Amy Kateleen Aldana de la Cruz
Ismael Lares-Asseff
Leslie Patrón-Romero
Horacio Almanza-Reyes
Randall Lou-Meda

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1592134

4,320 views
6 citations

Case Report

Published on 13 May 2025

Primary hyperoxaluria type I diagnosed after a kidney transplant presenting with subcutaneous calcification: a case report of sodium thiosulfate treatment

in Pharmacogenetics and Pharmacogenomics

Min Wu
Jing Lu
Yu-Jia Wang
Yong-Qi Li
Qing Wei
Yu-Xiang Gong
Ri-Ning Tang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1485024

2,116 views

Original Research

Published on 01 May 2025

Unveiling the heritability of selected unexplored pharmacogenetic markers in the Saudi population

in Pharmacogenetics and Pharmacogenomics

Mohammad A. Alshabeeb
Deemah Alwadaani
Sireen A. R. Shilbayeh
Fatemah A. Alherz
Ali Alghubayshi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1559399

3,784 views
1 citation

656 articles

articles

Global variation in antibiotic prescribing guidelines and the implications for decreasing AMR in the future

Clinicians’ experience on the effectiveness of pharmacotherapy in patients with first-episode depression: a randomized controlled trial based on pharmacogenomics

The role and challenges of intratumoral microbiota in colorectal cancer immunotherapy

Clinical significance and gene prediction of a novel classification system based on tacrolimus concentration-to-dose ratio in the early post-liver transplant period

Statins and their impact on epigenetic regulation: insights into disease

Polymorphisms in CYP3A5, CYP3A4, and ABCB1 genes: implications for calcineurin inhibitors therapy in hematopoietic cell transplantation recipients—a systematic review

Epigenetic modifications of gut microbiota and their potential role in atherosclerosis

Clinical and cost-effectiveness of pharmacogenomic testing for anthracycline-induced cardiotoxicity in childhood cancer: a systematic review and meta-analysis

Editorial: Editor’s feature: negative findings in pharmacogenetics and pharmacogenomics volume II

Editorial: Post-translational modifications in human cancer: pharmacological insights and therapeutic opportunities

Exploring biomarkers for noise-induced hearing loss through mitochondrial DNA methylation analysis

Editorial: Pharmacogenomics for improving drug safety and efficacy in cancer

CYP2C19 variability and clinical outcomes of clopidogrel, proton pump inhibitors, and voriconazole in Southeast Asia: a systematic review and meta-analysis

Hsa_circ_0002238 promotes the malignant behavior of colorectal cancer

Genetic polymorphisms as predictors of the response of hepatocellular carcinoma patients to doxorubicin chemotherapy: a genome-wide association study

Exosomal miR-24-3p mediates myoblast-macrophage crosstalk to promote abdominal muscle repair

Dynamic star allele definitions in Pharmacogenomics: impact on diplotype calls, Phenotype predictions and statin therapy recommendations

Biological and prognostic insights into the prostaglandin D2 signaling axis in lung adenocarcinoma

Implementation and integration of a multidisciplinary pharmacogenomics service in an underserved integrated behavioral health clinic

The role of endoplasmic reticulum aminopeptidase ERAP2 pathogenic mutation rs1363907 in amoxicillin clavulanate-induced liver injury: a special case report

ARID1A deficiency attenuates the response to EGFR-TKI treatment in lung adenocarcinoma

Impact of CYP3A5 1* and 3* single nucleotide variants on tacrolimus pharmacokinetics and graft rejection risk in pediatric kidney transplant patients

Primary hyperoxaluria type I diagnosed after a kidney transplant presenting with subcutaneous calcification: a case report of sodium thiosulfate treatment

Unveiling the heritability of selected unexplored pharmacogenetic markers in the Saudi population