Frontiers in Pharmacology | Pharmacogenetics and Pharmacogenomics

Review

Published on 08 Sep 2016

From Metabonomics to Pharmacometabonomics: The Role of Metabolic Profiling in Personalized Medicine

in Pharmacogenetics and Pharmacogenomics

Jeremy R. Everett

Frontiers in Pharmacology

doi 10.3389/fphar.2016.00297

10,918 views
53 citations

Original Research

Published on 29 Aug 2016

Photosensitivity to Triflusal: Formation of a Photoadduct with Ubiquitin Demonstrated by Photophysical and Proteomic Techniques

in Pharmacogenetics and Pharmacogenomics

Edurne Nuin
Dolores Pérez-Sala
Virginie Lhiaubet-Vallet
Inmaculada Andreu
Miguel A. Miranda

Frontiers in Pharmacology

doi 10.3389/fphar.2016.00277

3,080 views
10 citations

Original Research

Published on 26 Aug 2016

Killer Immunoglobulin-Like Receptor Profiles Are not Associated with Risk of Amoxicillin-Clavulanate–Induced Liver Injury in Spanish Patients

in Pharmacogenetics and Pharmacogenomics

Camilla Stephens
Antonia Moreno-Casares
Miguel-Ángel López-Nevot
Miren García-Cortés
Inmaculada Medina-Cáliz
Hacibe Hallal
German Soriano
Eva Roman
Francisco Ruiz-Cabello
Manuel Romero-Gomez

Frontiers in Pharmacology

doi 10.3389/fphar.2016.00280

3,566 views
3 citations

Mini Review

Published on 22 Aug 2016

Biomarkers in DILI: One More Step Forward

in Pharmacogenetics and Pharmacogenomics

Mercedes Robles-Díaz
Inmaculada Medina-Caliz
Camilla Stephens
Raúl J. Andrade
M. Isabel Lucena

Frontiers in Pharmacology

doi 10.3389/fphar.2016.00267

12,994 views
57 citations

Original Research

Published on 08 Aug 2016

Transitioning Pharmacogenomics into the Clinical Setting: Training Future Pharmacists

in Pharmacogenetics and Pharmacogenomics

Amber Frick
Cristina S. Benton
Kelly L. Scolaro
Jacqueline E. McLaughlin
Courtney L. Bradley
Oscar T. Suzuki
Nan Wang
Tim Wiltshire

Frontiers in Pharmacology

doi 10.3389/fphar.2016.00241

6,520 views
36 citations

Original Research

Published on 05 Aug 2016

Genetic Polymorphisms Associated to Folate Transport as Predictors of Increased Risk for Acute Lymphoblastic Leukemia in Mexican Children

in Pharmacogenetics and Pharmacogenomics

Fausto Zaruma-Torres
Ismael Lares-Asseff
Aurea Lima
Aarón Reyes-Espinoza
Verónica Loera-Castañeda
Martha Sosa-Macías
Carlos Galaviz-Hernández
María C. Arias-Peláez
Miguel A. Reyes-López
Luis A. Quiñones

Frontiers in Pharmacology

doi 10.3389/fphar.2016.00238

4,975 views
6 citations

Perspective

Published on 04 Aug 2016

Detoxifying Enzymes at the Cross-Roads of Inflammation, Oxidative Stress, and Drug Hypersensitivity: Role of Glutathione Transferase P1-1 and Aldose Reductase

in Pharmacogenetics and Pharmacogenomics

Francisco J. Sánchez-Gómez
Beatriz Díez-Dacal
Elena García-Martín
José A. G. Agúndez
María A. Pajares
Dolores Pérez-Sala

Frontiers in Pharmacology

doi 10.3389/fphar.2016.00237

9,443 views
38 citations

Original Research

Published on 20 Jul 2016

Asthma and Rhinitis Induced by Selective Immediate Reactions to Paracetamol and Non-steroidal Anti-inflammatory Drugs in Aspirin Tolerant Subjects

in Pharmacogenetics and Pharmacogenomics

Diana Pérez-Alzate
Natalia Blanca-López
Inmaculada Doña
José A. Agúndez
Elena García-Martín
José A. Cornejo-García
James R. Perkins
Miguel Blanca
Gabriela Canto

Frontiers in Pharmacology

doi 10.3389/fphar.2016.00215

8,037 views
18 citations

Original Research

Published on 18 Jul 2016

HLA-B*58:01 for Allopurinol-Induced Cutaneous Adverse Drug Reactions: Implication for Clinical Interpretation in Thailand

in Pharmacogenetics and Pharmacogenomics

Chonlaphat Sukasem
Thawinee Jantararoungtong
Parnrat Kuntawong
Apichaya Puangpetch
Napatrupron Koomdee
Patompong Satapornpong
Patcharin Supapsophon
Jettanong Klaewsongkram
Ticha Rerkpattanapipat

Frontiers in Pharmacology

doi 10.3389/fphar.2016.00186

17,367 views
65 citations

Review

Published on 12 Jul 2016

In vitro Models to Evaluate Drug-Induced Hypersensitivity: Potential Test Based on Activation of Dendritic Cells

in Pharmacogenetics and Pharmacogenomics

Valentina Galbiati
Angela Papale
Elena Kummer
Emanuela Corsini

Frontiers in Pharmacology

doi 10.3389/fphar.2016.00204

9,195 views
29 citations

Mini Review

Published on 17 Jun 2016

Basophil Reactivity as Biomarker in Immediate Drug Hypersensitivity Reactions—Potential and Limitations

in Pharmacogenetics and Pharmacogenomics

Markus Steiner
Andrea Harrer
Martin Himly

Frontiers in Pharmacology

doi 10.3389/fphar.2016.00171

9,498 views
28 citations

Original Research

Published on 14 Jun 2016

Pharmacometabolomic Assessment of Metformin in Non-diabetic, African Americans

in Pharmacogenetics and Pharmacogenomics

Daniel M. Rotroff
Noffisat O. Oki
Xiaomin Liang
Sook Wah Yee
Sophie L. Stocker
Daniel G. Corum
Michele Meisner
Oliver Fiehn
Alison A. Motsinger-Reif
Kathleen M. Giacomini

Frontiers in Pharmacology

doi 10.3389/fphar.2016.00135

7,270 views
35 citations

Mini Review

Published on 14 Jun 2016

MinION: A Novel Tool for Predicting Drug Hypersensitivity?

in Pharmacogenetics and Pharmacogenomics

Eng Wee Chua
Pei Yuen Ng

Frontiers in Pharmacology

doi 10.3389/fphar.2016.00156

6,492 views
8 citations

Original Research

Published on 25 Apr 2016

Functional Characterization of Human CYP2C9 Allelic Variants in COS-7 Cells

in Pharmacogenetics and Pharmacogenomics

Huihui Du
Zhiyun Wei
Yucai Yan
Yuyu Xiong
Xiaoqing Zhang
Lu Shen
Yunfeng Ruan
Xi Wu
Qingqing Xu
Lin He

Frontiers in Pharmacology

doi 10.3389/fphar.2016.00098

4,497 views
9 citations

Original Research

Published on 31 Mar 2016

Untargeted Metabolomics Reveals Dose-Response Characteristics for Effect of Rhubarb in a Rat Model of Cholestasis

in Pharmacogenetics and Pharmacogenomics

Cong-En Zhang
Ming Niu
Rui-Yu Li
Wu-Wen Feng
Xiao Ma
Qin Dong
Zhi-Jie Ma
Guang-Quan Li
Ya-Kun Meng
Ya Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2016.00085

6,767 views
31 citations

Original Research

Published on 28 Jan 2016

MicroRNA–mRNA Pairs Associated with Outcome in AML: From In Vitro Cell-Based Studies to AML Patients

in Pharmacogenetics and Pharmacogenomics

Neha S. Bhise
Lata Chauhan
Miyoung Shin
Xueyuan Cao
Stanley Pounds
Vishal Lamba
Jatinder K. Lamba

Frontiers in Pharmacology

doi 10.3389/fphar.2015.00324

6,842 views
22 citations

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Articles

From Metabonomics to Pharmacometabonomics: The Role of Metabolic Profiling in Personalized Medicine

Photosensitivity to Triflusal: Formation of a Photoadduct with Ubiquitin Demonstrated by Photophysical and Proteomic Techniques

Killer Immunoglobulin-Like Receptor Profiles Are not Associated with Risk of Amoxicillin-Clavulanate–Induced Liver Injury in Spanish Patients

Biomarkers in DILI: One More Step Forward

Transitioning Pharmacogenomics into the Clinical Setting: Training Future Pharmacists

Genetic Polymorphisms Associated to Folate Transport as Predictors of Increased Risk for Acute Lymphoblastic Leukemia in Mexican Children

Detoxifying Enzymes at the Cross-Roads of Inflammation, Oxidative Stress, and Drug Hypersensitivity: Role of Glutathione Transferase P1-1 and Aldose Reductase

Asthma and Rhinitis Induced by Selective Immediate Reactions to Paracetamol and Non-steroidal Anti-inflammatory Drugs in Aspirin Tolerant Subjects

HLA-B*58:01 for Allopurinol-Induced Cutaneous Adverse Drug Reactions: Implication for Clinical Interpretation in Thailand

In vitro Models to Evaluate Drug-Induced Hypersensitivity: Potential Test Based on Activation of Dendritic Cells

Basophil Reactivity as Biomarker in Immediate Drug Hypersensitivity Reactions—Potential and Limitations

Pharmacometabolomic Assessment of Metformin in Non-diabetic, African Americans

MinION: A Novel Tool for Predicting Drug Hypersensitivity?

Functional Characterization of Human CYP2C9 Allelic Variants in COS-7 Cells

Untargeted Metabolomics Reveals Dose-Response Characteristics for Effect of Rhubarb in a Rat Model of Cholestasis

MicroRNA–mRNA Pairs Associated with Outcome in AML: From In Vitro Cell-Based Studies to AML Patients