Frontiers in Pharmacology | Pharmacogenetics and Pharmacogenomics

Original Research

Published on 19 Mar 2025

Impact of CYP3A4 and ABCB1 genetic variants on tacrolimus dosing in Greek kidney transplant recipients

in Pharmacogenetics and Pharmacogenomics

Anna Tsironi
Konstantinos Lazaros
Effrosyni Mendrinou
Marios Papasotiriou
Stavroula Siamoglou
Kyriaki Kydonopoulou
Anne John
Alexandra Gerou
Spyridon Gerou
Bassam R. Ali

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1538432

2,578 views
1 citation

Editorial

Published on 17 Mar 2025

Editorial: Multi-omics technology: revealing the pathogenesis of diseases and the mechanism of drug efficacy of major diseases such as nutritional metabolism disorders and mental disorders

in Pharmacogenetics and Pharmacogenomics

Wenzhi Hao
Tianhao Liu
Xiliang Du
Gabriel Tao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1586223

1,108 views

Original Research

Published on 17 Mar 2025

Comprehensive pharmacogenomics profiling of the Serbian population

in Pharmacogenetics and Pharmacogenomics

Marina Jelovac
Djordje Pavlovic
Biljana Stankovic
Nikola Kotur
Bojan Ristivojevic
Sonja Pavlovic
Branka Zukic

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1553536

2,127 views

Brief Research Report

Published on 11 Mar 2025

Effect of CYP3A5 genotypes on pharmacokinetic of tacrolimus in colombian liver transplant patients

in Pharmacogenetics and Pharmacogenomics

Erica Fernanda Lindarte
Gonzalo De Jesus Vasquez
Luis Guillermo Toro Rendón
Andrés Felipe Zuluaga Salazar
Jefferson Antonio Buendia

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1505490

1,556 views

Original Research

Published on 05 Mar 2025

Allele and genotype frequencies of variants in P450 cytochromes, transports, and DNA repair enzymes in the Dominican Republic population

in Pharmacogenetics and Pharmacogenomics

Elizabeth Pérez-Duval
Berniza Calderón
Marlen Izquierdo
José A. Herrera-Isidrón
Elizabeth Reyes-Reyes
Alejandro Herrera
Manuel Soto
Alba Beltré
Idania Rodeiro-Guerra

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1494482

2,294 views
1 citation

Review

Published on 03 Mar 2025

Genome-wide functional annotation of variants: a systematic review of state-of-the-art tools, techniques and resources

in Pharmacogenetics and Pharmacogenomics

Eleftherios Pilalis
Dimitrios Zisis
Christina Andrinopoulou
Theodora Karamanidou
Maria Antonara
Thanos G. Stavropoulos
Aristotelis Chatziioannou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1474026

7,331 views
6 citations

Mini Review

Published on 27 Feb 2025

Precision medicine in colorectal cancer: genomics profiling and targeted treatment

in Pharmacogenetics and Pharmacogenomics

Adi Muradi Muhar
Adrian Joshua Velaro
Arya Tjipta Prananda
Sony Eka Nugraha
Princella Halim
Rony Abdi Syahputra

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1532971

3,954 views
4 citations

Original Research

Published on 21 Feb 2025

The CYP2D6 phenotyping performance of single-point saliva metabolic ratio in a healthy Chinese Han population

in Pharmacogenetics and Pharmacogenomics

Yongfa Huang
Zhangyuting He
Xiaoduo Guan
Pei Hu
Rui Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1438760

1,496 views

Mini Review

Published on 12 Feb 2025

Association between CYP2C19 polymorphism and proton pump inhibitors adverse drug reactions: a narrative review

in Pharmacogenetics and Pharmacogenomics

Asmaa Ibrahim
Kazeem Yusuff
Ahmed Awaisu
Hazem Elewa

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1523399

3,692 views
3 citations

Original Research

Published on 03 Feb 2025

Leveraging AI to automate detection and quantification of extrachromosomal DNA to decode drug responses

in Pharmacogenetics and Pharmacogenomics

Kohen Goble
Aarav Mehta
Damien Guilbaud
Jacob Fessler
Jingting Chen
William Nenad
Christina G. Ford
Oliver Cope
Darby Cheng
William Dennis

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1516621

3,336 views
3 citations

Original Research

Published on 30 Jan 2025

Deciphering the heterogeneity and plasticity of the tumor microenvironment in liver cancer provides insights for prognosis

in Pharmacogenetics and Pharmacogenomics

Yihao Sun
Guojuan Shi
Jian Yang
Chun-Zhong Zhou
Chuhan Peng
Yu-Hong Luo
Ying Pan
Rui-Qi Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1495280

2,601 views

Review

Published on 29 Jan 2025

Uncovering the role of microRNAs in esophageal cancer: from pathogenesis to clinical applications

in Pharmacogenetics and Pharmacogenomics

Zhenglin He
Yishuo Ji
Yutong Yuan
Tianfang Liang
Chenglin Liu
Yiping Jiao
Yimeng Chen
Yiming Yang
Liang Han
Yue Hu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1532558

3,023 views
3 citations

Original Research

Published on 22 Jan 2025

Better understanding the phenotypic effects of drugs through shared targets in genetic disease networks

in Pharmacogenetics and Pharmacogenomics

Elena Díaz-Santiago
Aurelio A. Moya-García
Jesús Pérez-García
Raquel Yahyaoui
Christine Orengo
Florencio Pazos
James R. Perkins
Juan A. G. Ranea

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1470931

2,394 views
1 citation

Original Research

Published on 07 Jan 2025

Pharmacogenetic and pharmacokinetic factors for dexmedetomidine-associated hemodynamic instability in pediatric patients

in Pharmacogenetics and Pharmacogenomics

Yanping Guan
Bilian Li
Yiyu Zhang
Hao Luo
Xueding Wang
Xue Bai
Zhuoling Zheng
Yaying Huang
Wei Wei
Min Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1515523

2,329 views
1 citation

Editorial

Published on 03 Jan 2025

Editorial: Insights in pharmacogenetics and pharmacogenomics: 2023

in Pharmacogenetics and Pharmacogenomics

José A. G. Agúndez
Elena García-Martín

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1540478

1,381 views

Original Research

Published on 03 Jan 2025

Exploring perceived barriers and attitudes in young adults towards antidepressant pharmacotherapy, including the implementation of pharmacogenetic testing to optimize prescription practices

in Pharmacogenetics and Pharmacogenomics

Bradley Roberts
Zahra Cooper
Georgia Landery
Susanne Stanley
Bernadette T. Majda
Khan R. L. Collins
P. Anthony Akkari
Sean D. Hood
Jennifer Rodger

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1526101

2,883 views
5 citations

Original Research

Published on 20 Dec 2024

Integration of pharmacogenetic data in epic genomic module drives clinical decision support alerts

in Pharmacogenetics and Pharmacogenomics

Kimberly J. Newsom
Bradley Hall
Katherine A. Martinez
Scott Nelson
Petr Starostik
Khoa Nguyen

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1458095

5,179 views
3 citations

Review

Published on 20 Dec 2024

Pharmacogenomics for neurodegenerative disorders - a focused review

in Pharmacogenetics and Pharmacogenomics

S. Rehan Ahmad
Md. Zeyaullah
Mohammad Suhail Khan
Abdullah M. AlShahrani
Abdelrhman A. Galaleldin Altijani
Haroon Ali
Adam Dawria
Ali Mohieldin
Mohammad Shane Alam
Awad Osman Abdalla Mohamed

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1478964

5,000 views
8 citations

Case Report

Published on 19 Dec 2024

Severe liver injury induced by minocycline in hepatitis B patient: a Case Report

in Pharmacogenetics and Pharmacogenomics

Ran Wang
Yun Li
Xue Xia

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1516217

2,435 views
1 citation

Review

Published on 16 Dec 2024

Pediatric flecainide pharmacogenomics: a roadmap to delivering precision-based care to pediatrics arrhythmias

in Pharmacogenetics and Pharmacogenomics

Ronald Palmen
Mollie Walton
Jonathan Wagner

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1477485

2,527 views

Original Research

Published on 11 Dec 2024

Paromomycin targets HDAC1-mediated SUMOylation and IGF1R translocation in glioblastoma

in Pharmacogenetics and Pharmacogenomics

Zhong Min
Yuejie Guo
Luo Ning

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1490878

1,752 views
1 citation

Brief Research Report

Published on 05 Dec 2024

Clinical implications of a gain-of-function genetic polymorphism in DPYD (rs4294451) in colorectal cancer patients treated with fluoropyrimidines

in Pharmacogenetics and Pharmacogenomics

Elena De Mattia
Jerry Polesel
Lucia Scarabel
Erika Cecchin

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1516375

2,366 views
5 citations

Original Research

Published on 04 Dec 2024

AH-6809 mediated regulation of lung adenocarcinoma metastasis through NLRP7 and prognostic analysis of key metastasis-related genes

in Pharmacogenetics and Pharmacogenomics

Xu Feng
Wei Wu
Feifei Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1486265

2,573 views
3 citations

Original Research

Published on 03 Dec 2024

Pharmacogenomic profiling of the South Korean population: Insights and implications for personalized medicine

in Pharmacogenetics and Pharmacogenomics

Mi Seon Youn
Se Hwan Ahn
Ju Han Kim

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1476765

4,417 views
3 citations

643 articles

articles

Impact of CYP3A4 and ABCB1 genetic variants on tacrolimus dosing in Greek kidney transplant recipients

Editorial: Multi-omics technology: revealing the pathogenesis of diseases and the mechanism of drug efficacy of major diseases such as nutritional metabolism disorders and mental disorders

Comprehensive pharmacogenomics profiling of the Serbian population

Effect of CYP3A5 genotypes on pharmacokinetic of tacrolimus in colombian liver transplant patients

Allele and genotype frequencies of variants in P450 cytochromes, transports, and DNA repair enzymes in the Dominican Republic population

Genome-wide functional annotation of variants: a systematic review of state-of-the-art tools, techniques and resources

Precision medicine in colorectal cancer: genomics profiling and targeted treatment

The CYP2D6 phenotyping performance of single-point saliva metabolic ratio in a healthy Chinese Han population

Association between CYP2C19 polymorphism and proton pump inhibitors adverse drug reactions: a narrative review

Leveraging AI to automate detection and quantification of extrachromosomal DNA to decode drug responses

Deciphering the heterogeneity and plasticity of the tumor microenvironment in liver cancer provides insights for prognosis

Uncovering the role of microRNAs in esophageal cancer: from pathogenesis to clinical applications

Better understanding the phenotypic effects of drugs through shared targets in genetic disease networks

Pharmacogenetic and pharmacokinetic factors for dexmedetomidine-associated hemodynamic instability in pediatric patients

Editorial: Insights in pharmacogenetics and pharmacogenomics: 2023

Exploring perceived barriers and attitudes in young adults towards antidepressant pharmacotherapy, including the implementation of pharmacogenetic testing to optimize prescription practices

Integration of pharmacogenetic data in epic genomic module drives clinical decision support alerts

Pharmacogenomics for neurodegenerative disorders - a focused review

Severe liver injury induced by minocycline in hepatitis B patient: a Case Report

Pediatric flecainide pharmacogenomics: a roadmap to delivering precision-based care to pediatrics arrhythmias

Paromomycin targets HDAC1-mediated SUMOylation and IGF1R translocation in glioblastoma

Clinical implications of a gain-of-function genetic polymorphism in DPYD (rs4294451) in colorectal cancer patients treated with fluoropyrimidines

AH-6809 mediated regulation of lung adenocarcinoma metastasis through NLRP7 and prognostic analysis of key metastasis-related genes

Pharmacogenomic profiling of the South Korean population: Insights and implications for personalized medicine