Frontiers in Pharmacology | Pharmacogenetics and Pharmacogenomics

Review

Published on 29 Jan 2025

Uncovering the role of microRNAs in esophageal cancer: from pathogenesis to clinical applications

in Pharmacogenetics and Pharmacogenomics

Zhenglin He
Yishuo Ji
Yutong Yuan
Tianfang Liang
Chenglin Liu
Yiping Jiao
Yimeng Chen
Yiming Yang
Liang Han
Yue Hu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1532558

3,321 views
6 citations

Original Research

Published on 22 Jan 2025

Better understanding the phenotypic effects of drugs through shared targets in genetic disease networks

in Pharmacogenetics and Pharmacogenomics

Elena Díaz-Santiago
Aurelio A. Moya-García
Jesús Pérez-García
Raquel Yahyaoui
Christine Orengo
Florencio Pazos
James R. Perkins
Juan A. G. Ranea

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1470931

2,658 views
1 citation

Original Research

Published on 07 Jan 2025

Pharmacogenetic and pharmacokinetic factors for dexmedetomidine-associated hemodynamic instability in pediatric patients

in Pharmacogenetics and Pharmacogenomics

Yanping Guan
Bilian Li
Yiyu Zhang
Hao Luo
Xueding Wang
Xue Bai
Zhuoling Zheng
Yaying Huang
Wei Wei
Min Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1515523

2,513 views
1 citation

Editorial

Published on 03 Jan 2025

Editorial: Insights in pharmacogenetics and pharmacogenomics: 2023

in Pharmacogenetics and Pharmacogenomics

José A. G. Agúndez
Elena García-Martín

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1540478

1,608 views

Original Research

Published on 03 Jan 2025

Exploring perceived barriers and attitudes in young adults towards antidepressant pharmacotherapy, including the implementation of pharmacogenetic testing to optimize prescription practices

in Pharmacogenetics and Pharmacogenomics

Bradley Roberts
Zahra Cooper
Georgia Landery
Susanne Stanley
Bernadette T. Majda
Khan R. L. Collins
P. Anthony Akkari
Sean D. Hood
Jennifer Rodger

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1526101

3,179 views
5 citations

Original Research

Published on 20 Dec 2024

Integration of pharmacogenetic data in epic genomic module drives clinical decision support alerts

in Pharmacogenetics and Pharmacogenomics

Kimberly J. Newsom
Bradley Hall
Katherine A. Martinez
Scott Nelson
Petr Starostik
Khoa Nguyen

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1458095

5,848 views
3 citations

Review

Published on 20 Dec 2024

Pharmacogenomics for neurodegenerative disorders - a focused review

in Pharmacogenetics and Pharmacogenomics

S. Rehan Ahmad
Md. Zeyaullah
Mohammad Suhail Khan
Abdullah M. AlShahrani
Abdelrhman A. Galaleldin Altijani
Haroon Ali
Adam Dawria
Ali Mohieldin
Mohammad Shane Alam
Awad Osman Abdalla Mohamed

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1478964

5,518 views
12 citations

Case Report

Published on 19 Dec 2024

Severe liver injury induced by minocycline in hepatitis B patient: a Case Report

in Pharmacogenetics and Pharmacogenomics

Ran Wang
Yun Li
Xue Xia

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1516217

2,783 views
1 citation

Review

Published on 16 Dec 2024

Pediatric flecainide pharmacogenomics: a roadmap to delivering precision-based care to pediatrics arrhythmias

in Pharmacogenetics and Pharmacogenomics

Ronald Palmen
Mollie Walton
Jonathan Wagner

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1477485

2,825 views

Original Research

Published on 11 Dec 2024

Paromomycin targets HDAC1-mediated SUMOylation and IGF1R translocation in glioblastoma

in Pharmacogenetics and Pharmacogenomics

Zhong Min
Yuejie Guo
Luo Ning

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1490878

1,924 views
1 citation

Brief Research Report

Published on 05 Dec 2024

Clinical implications of a gain-of-function genetic polymorphism in DPYD (rs4294451) in colorectal cancer patients treated with fluoropyrimidines

in Pharmacogenetics and Pharmacogenomics

Elena De Mattia
Jerry Polesel
Lucia Scarabel
Erika Cecchin

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1516375

2,562 views
5 citations

Original Research

Published on 04 Dec 2024

AH-6809 mediated regulation of lung adenocarcinoma metastasis through NLRP7 and prognostic analysis of key metastasis-related genes

in Pharmacogenetics and Pharmacogenomics

Xu Feng
Wei Wu
Feifei Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1486265

2,788 views
3 citations

Original Research

Published on 03 Dec 2024

Pharmacogenomic profiling of the South Korean population: Insights and implications for personalized medicine

in Pharmacogenetics and Pharmacogenomics

Mi Seon Youn
Se Hwan Ahn
Ju Han Kim

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1476765

4,727 views
4 citations

Review

Published on 28 Nov 2024

Advancements in precision medicine: multi-omics approach for tailored metformin treatment in type 2 diabetes

in Pharmacogenetics and Pharmacogenomics

Najeha Rizwana Anwardeen
Khaled Naja
Mohamed A. Elrayess

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1506767

5,291 views
10 citations

Original Research

Published on 25 Nov 2024

Comparing commercial pharmacogenetic testing results and recommendations for antidepressants with established CPIC guidelines

in Pharmacogenetics and Pharmacogenomics

Tiffany T. Nguyen
Emili J. W. Leary
Joshua T. Lee
Sanjay K. Shukla
Sara A. Griesbach

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1500235

3,736 views
3 citations

Original Research

Published on 20 Nov 2024

Metabolic pathways, genomic alterations, and post-translational modifications in pulmonary hypertension and cancer as therapeutic targets and biomarkers

in Pharmacogenetics and Pharmacogenomics

Xiujin Zhang
Zhiqing Fu
Haijun Wang
Li Sheng

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1490892

3,099 views
2 citations

Original Research

Published on 18 Nov 2024

Investigation on regulation of N-acetyltransferase 2 expression by nuclear receptors in human hepatocytes

in Pharmacogenetics and Pharmacogenomics

Kyung U. Hong
Anthony P. Aureliano
Kennedy M. Walls
David W. Hein

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1488367

2,486 views
1 citation

Original Research

Published on 15 Nov 2024

Population pharmacokinetic study of the effect of polymorphisms in the ABCB1 and CES1 genes on the pharmacokinetics of dabigatran

in Pharmacogenetics and Pharmacogenomics

Zhuan Yang
Wen Rui Tan
Qin Li
Ying Wang
Shijing Liu
Lu Chen
Yan Zhou
Chen Zeng
Yan Zeng
Yun Xiong

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1454612

2,422 views
1 citation

Original Research

Published on 14 Nov 2024

Novel genomic variants influencing methotrexate delayed clearance in pediatric patients with acute lymphoblastic leukemia

in Pharmacogenetics and Pharmacogenomics

Jung Yoon Choi
Hoshik Kwon
Hyery Kim
Kyung Taek Hong
Youngeun Ma
Kyung-Nam Koh
Sunmin Yun
Keon Hee Yoo
Sang Hoon Song
Ho Joon Im

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1480657

3,071 views
4 citations

Review

Published on 12 Nov 2024

Tumor microenvironment and cancer metastasis: molecular mechanisms and therapeutic implications

in Pharmacogenetics and Pharmacogenomics

Cigir Biray Avci
Bakiye Goker Bagca
Masoud Nikanfar
Leila Sabour Takanlou
Maryam Sabour Takanlou
Alireza Nourazarian

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1442888

12,436 views
52 citations

Original Research

Published on 01 Nov 2024

Multi-omics association study integrating GWAS and pQTL data revealed MIP-1α as a potential drug target for erectile dysfunction

in Pharmacogenetics and Pharmacogenomics

Jingwen Liu
Renbing Pan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1495970

3,498 views
1 citation

Original Research

Published on 01 Nov 2024

Allele frequencies and genotype distribution of three metformin transporter polymorphisms in Mexican population and their application in pharmacogenomics of type 2 diabetes

in Pharmacogenetics and Pharmacogenomics

Oscar I. Chávez-Arreola
Brissia Lazalde
Marisol López-López
Alberto Ortega-Vázquez
Quitzia L. Torres-Salazar

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1466394

2,308 views

Original Research

Published on 30 Oct 2024

The role of candidate pharmacogenetic variants in determining valproic acid efficacy, toxicity and concentrations in patients with epilepsy

in Pharmacogenetics and Pharmacogenomics

Hady Yazbeck
Joe Youssef
Wassim Nasreddine
Abdullah El Kurdi
Nathalie Zgheib
Ahmad Beydoun

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1483723

2,710 views
2 citations

Original Research

Published on 25 Oct 2024

A mathematical model of glomerular fibrosis in diabetic kidney disease to predict therapeutic efficacy

in Pharmacogenetics and Pharmacogenomics

Haryana Y. Thomas
Ashlee N. Ford Versypt

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1481768

3,028 views
3 citations

656 articles

articles

Uncovering the role of microRNAs in esophageal cancer: from pathogenesis to clinical applications

Better understanding the phenotypic effects of drugs through shared targets in genetic disease networks

Pharmacogenetic and pharmacokinetic factors for dexmedetomidine-associated hemodynamic instability in pediatric patients

Editorial: Insights in pharmacogenetics and pharmacogenomics: 2023

Exploring perceived barriers and attitudes in young adults towards antidepressant pharmacotherapy, including the implementation of pharmacogenetic testing to optimize prescription practices

Integration of pharmacogenetic data in epic genomic module drives clinical decision support alerts

Pharmacogenomics for neurodegenerative disorders - a focused review

Severe liver injury induced by minocycline in hepatitis B patient: a Case Report

Pediatric flecainide pharmacogenomics: a roadmap to delivering precision-based care to pediatrics arrhythmias

Paromomycin targets HDAC1-mediated SUMOylation and IGF1R translocation in glioblastoma

Clinical implications of a gain-of-function genetic polymorphism in DPYD (rs4294451) in colorectal cancer patients treated with fluoropyrimidines

AH-6809 mediated regulation of lung adenocarcinoma metastasis through NLRP7 and prognostic analysis of key metastasis-related genes

Pharmacogenomic profiling of the South Korean population: Insights and implications for personalized medicine

Advancements in precision medicine: multi-omics approach for tailored metformin treatment in type 2 diabetes

Comparing commercial pharmacogenetic testing results and recommendations for antidepressants with established CPIC guidelines

Metabolic pathways, genomic alterations, and post-translational modifications in pulmonary hypertension and cancer as therapeutic targets and biomarkers

Investigation on regulation of N-acetyltransferase 2 expression by nuclear receptors in human hepatocytes

Population pharmacokinetic study of the effect of polymorphisms in the ABCB1 and CES1 genes on the pharmacokinetics of dabigatran

Novel genomic variants influencing methotrexate delayed clearance in pediatric patients with acute lymphoblastic leukemia

Tumor microenvironment and cancer metastasis: molecular mechanisms and therapeutic implications

Multi-omics association study integrating GWAS and pQTL data revealed MIP-1α as a potential drug target for erectile dysfunction

Allele frequencies and genotype distribution of three metformin transporter polymorphisms in Mexican population and their application in pharmacogenomics of type 2 diabetes

The role of candidate pharmacogenetic variants in determining valproic acid efficacy, toxicity and concentrations in patients with epilepsy

A mathematical model of glomerular fibrosis in diabetic kidney disease to predict therapeutic efficacy