Frontiers in Pharmacology | Pharmacogenetics and Pharmacogenomics

Original Research

Published on 31 Jan 2024

Racial disparities in metastatic colorectal cancer outcomes revealed by tumor microbiome and transcriptome analysis with bevacizumab treatment

in Pharmacogenetics and Pharmacogenomics

Lei Feng
Rui Wang
Qian Zhao
Jun Wang
Gang Luo
Chongwen Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1320028

3,873 views
4 citations

Review

Published on 30 Jan 2024

Advances in the study of marketed antibody-drug Conjugates (ADCs) for the treatment of breast cancer

in Pharmacogenetics and Pharmacogenomics

Yan Liang
Purong Zhang
Feng Li
Houyun Lai
Tingting Qi
Yixin Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1332539

8,566 views
9 citations

Mini Review

Published on 24 Jan 2024

Precision medicine: a new era for inner ear diseases

in Pharmacogenetics and Pharmacogenomics

Elisa Tavazzani
Paolo Spaiardi
Donatella Contini
Giulio Sancini
Giancarlo Russo
Sergio Masetto

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1328460

5,889 views
6 citations

Review

Published on 19 Jan 2024

Potential of CDC25 phosphatases in cancer research and treatment: key to precision medicine

in Pharmacogenetics and Pharmacogenomics

Ibraheem Dakilah
Amani Harb
Eman Abu-Gharbieh
Waseem El-Huneidi
Jalal Taneera
Rifat Hamoudi
Mohammed H. Semreen
Yasser Bustanji

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1324001

7,714 views
17 citations

Review

Published on 09 Jan 2024

Machine learning in onco-pharmacogenomics: a path to precision medicine with many challenges

in Pharmacogenetics and Pharmacogenomics

Alessia Mondello
Michele Dal Bo
Giuseppe Toffoli
Maurizio Polano

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1260276

23,650 views
16 citations

Original Research

Published on 08 Jan 2024

CYP3A5 influences oral tacrolimus pharmacokinetics and timing of acute kidney injury following allogeneic hematopoietic stem cell transplantation

in Pharmacogenetics and Pharmacogenomics

Nathan D. Seligson
Xunjie Zhang
Mark C. Zemanek
Jasmine A. Johnson
Zachary VanGundy
Danxin Wang
Mitch A. Phelps
Julianna Roddy
Craig C. Hofmeister
Junan Li

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1334440

3,337 views
6 citations

Original Research

Published on 03 Jan 2024

Transcriptomic and metabolomic analysis of peri-tumoral hepatic tissue in hepatocellular carcinoma: unveiling the molecular landscape of immune checkpoint therapy resistance

in Pharmacogenetics and Pharmacogenomics

Huaqiang Bi
Kai Feng
Xiaofei Wang
Ping Zheng
Chengming Qu
Kuansheng Ma

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1304996

2,295 views
1 citation

Case Report

Published on 03 Jan 2024

Organ-specific immune-mediated reactions to polyethylene glycol and polysorbate excipients: three case reports

in Pharmacogenetics and Pharmacogenomics

Olga Rogozina
Carmen Ruiz-Fernández
Susana Martín-López
Ibtissam Akatbach-Bousaid
Miguel González-Muñoz
Elena Ramírez

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1293294

3,806 views
7 citations

Review

Published on 12 Dec 2023

Stilbenes: a promising small molecule modulator for epigenetic regulation in human diseases

in Pharmacogenetics and Pharmacogenomics

Jing Tian
Li Jin
Hongquan Liu
Zichun Hua

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1326682

5,330 views
23 citations

Review

Published on 11 Dec 2023

Drug repositioning in thyroid cancer treatment: the intriguing case of anti-diabetic drugs

in Pharmacogenetics and Pharmacogenomics

Alessia Greco
Francesca Coperchini
Laura Croce
Flavia Magri
Marsida Teliti
Mario Rotondi

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1303844

5,403 views
9 citations

Review

Published on 01 Dec 2023

Antihypertensives associated adverse events: a review of mechanisms and pharmacogenomic biomarkers available evidence in multi-ethnic populations

in Pharmacogenetics and Pharmacogenomics

Sahar M. Altoum
Zeina N. Al-Mahayri
Bassam R. Ali

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1286494

6,355 views
4 citations

Original Research

Published on 28 Nov 2023

miR-6805-5p as a biomarker of cisplatin-induced nephrotoxicity in patients with head and neck cancer

in Pharmacogenetics and Pharmacogenomics

Nadine De Godoy Torso
Julia Coelho França Quintanilha
Maria Aparecida Cursino
Eder De Carvalho Pincinato
Pía Loren
Luis A. Salazar
Carmen Silvia Passos Lima
Patricia Moriel

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1275238

2,636 views
7 citations

Original Research

Published on 22 Nov 2023

Single-nucleotide polymorphism profiling by multimodal-targeted next-generation sequencing in methotrexate-resistant and -sensitive human osteosarcoma cell lines

in Pharmacogenetics and Pharmacogenomics

Chiara Casotti
Claudia Maria Hattinger
Maria Pia Patrizio
Silvia Luppi
Leonardo Fantoni
Michela Pasello
Katia Scotlandi
Toni Ibrahim
Massimo Serra

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1294873

3,073 views
1 citation

Brief Research Report

Published on 17 Nov 2023

Pharmacogenetics of pediatric acute lymphoblastic leukemia in Uruguay: adverse events related to induction phase drugs

in Pharmacogenetics and Pharmacogenomics

Gabriela Burgueño-Rodríguez
Yessika Méndez
Natalia Olano
Magdalena Schelotto
Luis Castillo
Ana María Soler
Julio da Luz

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1278769

4,002 views
2 citations

Original Research

Published on 15 Nov 2023

Human N-acetyltransferase 2 (NAT2) gene variability in Brazilian populations from different geographical areas

in Pharmacogenetics and Pharmacogenomics

Márcia Quinhones P. Lopes
Raquel Lima F. Teixeira
Pedro Hernan Cabello
José Augusto C. Nery
Anna Maria Sales
Edilbert Pellegrini Nahn J. R.
Marilda Vieira Moreira
Ewalda Von Rosen Stahlke
Lia Gonçalves Possuelo
Maria Lucia R. Rossetti

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1278720

5,003 views
4 citations

Original Research

Published on 15 Nov 2023

Construction of a risk scoring system using clinical factors and RYR2 polymorphisms for bleeding complications in patients on direct oral anticoagulants

in Pharmacogenetics and Pharmacogenomics

Eun Jeong Jang
Jung Sun Kim
Seo A. Choi
Jeong Yee
Tae-Jin Song
Junbeom Park
Hye Sun Gwak

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1290785

2,094 views
2 citations

Methods

Published on 14 Nov 2023

Evolution of pharmacogenomic services and implementation of a multi-state pharmacogenomics clinic across a large rural healthcare system

in Pharmacogenetics and Pharmacogenomics

Joel Van Heukelom
Jennifer Morgan
Amanda Massmann
Kristen Jacobsen
Natasha J. Petry
Jordan F. Baye
Samantha Frear
April Schultz

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1274165

4,170 views
4 citations

Original Research

Published on 13 Nov 2023

Targeted haplotyping in pharmacogenomics using Oxford Nanopore Technologies’ adaptive sampling

in Pharmacogenetics and Pharmacogenomics

Koen Deserranno
Laurentijn Tilleman
Kaat Rubben
Dieter Deforce
Filip Van Nieuwerburgh

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1286764

10,220 views
10 citations

Case Report

Published on 09 Nov 2023

HLA-targeted sequencing reveals the pathogenic role of HLA-B15:02/HLA-B13:01 in albendazole-induced liver failure: a case report and a review of the literature

in Pharmacogenetics and Pharmacogenomics

Jin-Mao Liao
Yan Zhan
Zheng Zhang
Jia-Jia Cui
Ji-Ye Yin

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1288068

2,693 views
8 citations

Original Research

Published on 06 Nov 2023

CYP450 and drug efflux transporters polymorphism influence clinical outcomes of Thai osimertinib-treated non-small cell lung cancer patients

in Pharmacogenetics and Pharmacogenomics

Teerapat Majam
Chonlaphat Sukasem
Thanyanan Reungwetwattana
Phichai Chansriwong
Chalirmporn Atasilp
Narumol Trachu
Thanaporn Thamrongjirapat
Rattanaporn Sukprasong
Jennis Meanwatthana

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1222435

4,237 views
7 citations

Editorial

Published on 03 Nov 2023

Editorial: Multi-omics approaches for decoding heterogeneity in cancer immunotherapy

in Pharmacogenetics and Pharmacogenomics

Aimin Jiang
Ying Liu
Ouyang Chen
Zhigang Liu
Hongzhou Cai
Linhui Wang
Lin Qi

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1324212

3,039 views
5 citations

Editorial

Published on 27 Oct 2023

Editorial: Emerging talents in frontiers in pharmacology: pharmacogenetics and pharmacogenomics 2022

in Pharmacogenetics and Pharmacogenomics

Sylvia D. Klomp
Ana Alfirevic

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1307602

6,585 views

Brief Research Report

Published on 20 Oct 2023

Pharmacogenomics in clinical trials: an overview

in Pharmacogenetics and Pharmacogenomics

Rita Nogueiras-Álvarez

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1247088

7,960 views
19 citations

Original Research

Published on 19 Oct 2023

Advancing pharmacogenetic testing in a tertiary hospital: a retrospective analysis after 10 years of activity

in Pharmacogenetics and Pharmacogenomics

Stefan Stewart
Jose Manuel Dodero-Anillo
Javier Guijarro-Eguinoa
Pedro Arias
Arturo Gómez López De Las Huertas
Enrique Seco-Meseguer
Irene García-García
Elena Ramírez García
Carlos Rodríguez-Antolín
Antonio J. Carcas

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1292416

4,110 views
10 citations

643 articles

articles

Racial disparities in metastatic colorectal cancer outcomes revealed by tumor microbiome and transcriptome analysis with bevacizumab treatment

Advances in the study of marketed antibody-drug Conjugates (ADCs) for the treatment of breast cancer

Precision medicine: a new era for inner ear diseases

Potential of CDC25 phosphatases in cancer research and treatment: key to precision medicine

Machine learning in onco-pharmacogenomics: a path to precision medicine with many challenges

CYP3A5 influences oral tacrolimus pharmacokinetics and timing of acute kidney injury following allogeneic hematopoietic stem cell transplantation

Transcriptomic and metabolomic analysis of peri-tumoral hepatic tissue in hepatocellular carcinoma: unveiling the molecular landscape of immune checkpoint therapy resistance

Organ-specific immune-mediated reactions to polyethylene glycol and polysorbate excipients: three case reports

Stilbenes: a promising small molecule modulator for epigenetic regulation in human diseases

Drug repositioning in thyroid cancer treatment: the intriguing case of anti-diabetic drugs

Antihypertensives associated adverse events: a review of mechanisms and pharmacogenomic biomarkers available evidence in multi-ethnic populations

miR-6805-5p as a biomarker of cisplatin-induced nephrotoxicity in patients with head and neck cancer

Single-nucleotide polymorphism profiling by multimodal-targeted next-generation sequencing in methotrexate-resistant and -sensitive human osteosarcoma cell lines

Pharmacogenetics of pediatric acute lymphoblastic leukemia in Uruguay: adverse events related to induction phase drugs

Human N-acetyltransferase 2 (NAT2) gene variability in Brazilian populations from different geographical areas

Construction of a risk scoring system using clinical factors and RYR2 polymorphisms for bleeding complications in patients on direct oral anticoagulants

Evolution of pharmacogenomic services and implementation of a multi-state pharmacogenomics clinic across a large rural healthcare system

Targeted haplotyping in pharmacogenomics using Oxford Nanopore Technologies’ adaptive sampling

HLA-targeted sequencing reveals the pathogenic role of HLA-B15:02/HLA-B13:01 in albendazole-induced liver failure: a case report and a review of the literature

CYP450 and drug efflux transporters polymorphism influence clinical outcomes of Thai osimertinib-treated non-small cell lung cancer patients

Editorial: Multi-omics approaches for decoding heterogeneity in cancer immunotherapy

Editorial: Emerging talents in frontiers in pharmacology: pharmacogenetics and pharmacogenomics 2022

Pharmacogenomics in clinical trials: an overview

Advancing pharmacogenetic testing in a tertiary hospital: a retrospective analysis after 10 years of activity

articles

Racial disparities in metastatic colorectal cancer outcomes revealed by tumor microbiome and transcriptome analysis with bevacizumab treatment

Advances in the study of marketed antibody-drug Conjugates (ADCs) for the treatment of breast cancer

Precision medicine: a new era for inner ear diseases

Potential of CDC25 phosphatases in cancer research and treatment: key to precision medicine

Machine learning in onco-pharmacogenomics: a path to precision medicine with many challenges

CYP3A5 influences oral tacrolimus pharmacokinetics and timing of acute kidney injury following allogeneic hematopoietic stem cell transplantation

Transcriptomic and metabolomic analysis of peri-tumoral hepatic tissue in hepatocellular carcinoma: unveiling the molecular landscape of immune checkpoint therapy resistance

Organ-specific immune-mediated reactions to polyethylene glycol and polysorbate excipients: three case reports

Stilbenes: a promising small molecule modulator for epigenetic regulation in human diseases

Drug repositioning in thyroid cancer treatment: the intriguing case of anti-diabetic drugs

Antihypertensives associated adverse events: a review of mechanisms and pharmacogenomic biomarkers available evidence in multi-ethnic populations

miR-6805-5p as a biomarker of cisplatin-induced nephrotoxicity in patients with head and neck cancer

Single-nucleotide polymorphism profiling by multimodal-targeted next-generation sequencing in methotrexate-resistant and -sensitive human osteosarcoma cell lines

Pharmacogenetics of pediatric acute lymphoblastic leukemia in Uruguay: adverse events related to induction phase drugs

Human N-acetyltransferase 2 (NAT2) gene variability in Brazilian populations from different geographical areas

Construction of a risk scoring system using clinical factors and RYR2 polymorphisms for bleeding complications in patients on direct oral anticoagulants

Evolution of pharmacogenomic services and implementation of a multi-state pharmacogenomics clinic across a large rural healthcare system

Targeted haplotyping in pharmacogenomics using Oxford Nanopore Technologies’ adaptive sampling

HLA-targeted sequencing reveals the pathogenic role of HLA-B*15:02/HLA-B*13:01 in albendazole-induced liver failure: a case report and a review of the literature

CYP450 and drug efflux transporters polymorphism influence clinical outcomes of Thai osimertinib-treated non-small cell lung cancer patients

Editorial: Multi-omics approaches for decoding heterogeneity in cancer immunotherapy

Editorial: Emerging talents in frontiers in pharmacology: pharmacogenetics and pharmacogenomics 2022

Pharmacogenomics in clinical trials: an overview

Advancing pharmacogenetic testing in a tertiary hospital: a retrospective analysis after 10 years of activity

HLA-targeted sequencing reveals the pathogenic role of HLA-B15:02/HLA-B13:01 in albendazole-induced liver failure: a case report and a review of the literature