Frontiers in Pharmacology | Pharmacology of Anti-Cancer Drugs

Original Research

Accepted on 04 Jul 2025

Doxorubicin Delivery by pYEEIE Peptide-Functionalized Rhodiola rosea-Derived Exosome-Like Nanovesicles for Targeted Melanoma Therapy

in Pharmacology of Anti-Cancer Drugs

Chen Wang
Duan Meitao
Binbin Chen
Xue Yi
Ahmed Mahal
Linwei Song
Moxun Xu
Ahmad J Obaidullah
Shuwei Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1619998

125 views

Review

Published on 04 Jul 2025

MicroRNA-145 in urologic tumors: biological roles, regulatory networks, and clinical translation

in Pharmacology of Anti-Cancer Drugs

Lifeng Gan
Wei Li
Qi Chen
Le Cheng
Fangtao Zhang
Haidong Zhong
Yiran Lu
Liying Zheng
Biao Qian

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1609646

220 views

Review

Published on 04 Jul 2025

Review projecting shikonin as a therapeutic candidate in female carcinomas: a preclinical perspective

in Pharmacology of Anti-Cancer Drugs

Pratibha Pandey
Sorabh Lakhanpal
K. V. Jamuna
Ajay Singh
Mohammad Abohassan
Moon Nyeo Park
Sang-Won Shin
Han Na Kang
Manaal Zahera
Mohd Saeed

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1627124

280 views

Methods

Published on 04 Jul 2025

HRS-4642 combined with nimotuzumab in the treatment of recurrent or metastatic pancreatic ductal adenocarcinoma: study protocol of a single-arm, prospective phase Ib/II trial

in Pharmacology of Anti-Cancer Drugs

Qingqing Leng
Jitao Zhou
Xin Wang
Pei Zhang
Huanji Xu
Dan Cao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1562481

293 views

Review

Accepted on 03 Jul 2025

Mechanism and Application of Copper-Based Nanomedicines in Activating Tumor Immunity through Oxidative Stress Modulation

in Pharmacology of Anti-Cancer Drugs

Cong Xia
Zirun Luo
Zhen Feng
Qianshi Zhang
Chenglai Xia

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1646890

Original Research

Published on 03 Jul 2025

Efficacy and safety of leuprorelin (Boennuokang®) plus endocrine therapy in premenopausal women with HR+/HER2− breast cancer

in Pharmacology of Anti-Cancer Drugs

Xiuping Wu
Yinfeng Lin
Wangmei Xie
Yan Jiang
Zhenchao Xu
Kai He
Shuyu Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1594799

314 views

Original Research

Published on 03 Jul 2025

Multi-omics analysis of the anti-cancer effects of curcumol in endometrial carcinoma

in Pharmacology of Anti-Cancer Drugs

Jumin Xie
Ying Zhu
Haozhen Bai
Zean Song
Shukai Qiu
Youyi Xie
Shuqiong Wan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1565959

375 views

Review

Published on 02 Jul 2025

Regulation of anti-tumour effects of Paris polyphylla saponins via ROS: molecular mechanisms and therapeutic potentials

in Pharmacology of Anti-Cancer Drugs

Jia Liu
Yongping Mu
Ke Qi
Jiayi Li
Yang Hu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1611911

274 views

Original Research

Accepted on 01 Jul 2025

Exposure-response analyses of venetoclax combined with hypomethylating agents in myelodysplastic syndromes: a retrospective study

in Pharmacology of Anti-Cancer Drugs

Jixin Tian
Ping Zhang
Xiao-Xu Wang
Jin-Wen Li
Dong-Xue Liu
Yi-Ying Liu
Zhijian Xiao
Wen-Juan Miao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1586910

194 views

Original Research

Accepted on 01 Jul 2025

The functional roles of deoxyelephantopin potential target circTNPO3 in regulating pancreatic cancer malignant phenotype and gemcitabine chemoresistance via miR-188-5p/CDCA3/TRAF2-mediated remodeling of NF-κB signaling pathway

in Pharmacology of Anti-Cancer Drugs

Daolin Ji
Jia Liu
Yanhui Zhang
Li Hou
Haonan Feng
Xue Xing
Deming Guan
Tiangang Cui
Yi Xu
Gang Tan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1613560

119 views

Review

Published on 01 Jul 2025

Curcumin, EGCG and apigenin in cervical cancer: mechanistic insights and therapeutic potential

in Pharmacology of Anti-Cancer Drugs

Abdulaziz Asiri
Bayan T. Bokahri
Sadaf
Alaa Abdulaziz Eisa
Hashim M. Aljohani
Wesam Nofal
Tahreem Kausar
Mohammad Zeeshan Najm

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1592395

438 views

Opinion

Accepted on 30 Jun 2025

The Rho/MRTF-Pirin Axis: A Promising Target for Overcoming Melanoma Drug Resistance

in Pharmacology of Anti-Cancer Drugs

Xiaoyan Chen
Junfeng Zhang
Jiuhu Li
Zhi Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1571933

116 views

Mini Review

Accepted on 30 Jun 2025

Advancements in Bladder Cancer Immunotherapy: A Focus on Intravesical Approaches

in Pharmacology of Anti-Cancer Drugs

Xia Tang
Tianlun Yu
Hongxuan Tong
Yufan Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1578146

123 views

Original Research

Accepted on 30 Jun 2025

Quercetin inhibits the cAMP/PKA/CREB/glycolysis axis to exert anti-acute lymphoblastic leukemia effects

in Pharmacology of Anti-Cancer Drugs

Qiuling Ma
Wenqing Liu
Yajing Su
Jue Guo
Man Zhang
Jiayuan Guo
Mingxin Liu
Wenbo Dong
Mingwei Li
Bo Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1614973

106 views

Original Research

Accepted on 30 Jun 2025

CDFA: calibrated deep feature aggregation for screening synergistic drug combinations

in Pharmacology of Anti-Cancer Drugs

Xiaorui Kang
XIAOYAN LIU
Quan Zou
Tiantian Li
Ximei Luo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1608832

109 views

Systematic Review

Accepted on 30 Jun 2025

Long-term Efficacy of CDK4/6 Inhibitors in Early HR+, HER2-High-Risk Breast Cancer: An Updated Systematic Review and Meta-Analysis

in Pharmacology of Anti-Cancer Drugs

Ying Liu
Jun Su
Ping Wu
Wenjie Lv

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1564437