Frontiers in Pharmacology | Pharmacology of Anti-Cancer Drugs

Original Research

Published on 10 Apr 2025

Pan-cancer analysis identified CD248 as a potential target for multiple tumor types

in Pharmacology of Anti-Cancer Drugs

Li Guo
Yan Liao
Xuyang Zhang
Rongjuan Guo
Zheng Wang
Deqin Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1554632

1,534 views

Original Research

Published on 09 Apr 2025

The biological function and prognostic significance of ferroptosis-related genes in clear cell renal cell carcinoma

in Pharmacology of Anti-Cancer Drugs

Huizhen Ye
Xiwen Wu
Gehao Liang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1515552

1,259 views

Review

Published on 08 Apr 2025

A novel perspective on bone tumors: advances in organoid research

in Pharmacology of Anti-Cancer Drugs

Zebing Ma
Yibing Liu
Rui Chen
Huayu Fan
Liang Kong
Xiangyang Cao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1550163

1,304 views

Original Research

Published on 08 Apr 2025

MDM2 inhibitor induces apoptosis in colon cancer cells through activation of the CHOP-DR5 pathway, independent of p53 phenotype

in Pharmacology of Anti-Cancer Drugs

Manman Lu
Yingli Ren
Sijia Feng
Shenggen Wang
Weiyue Xia
Baoru Gu
Yuhou Shen
Aimin Yue
Na Li
Yongxi Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1508421

1,490 views

Original Research

Published on 07 Apr 2025

Miltirone enhances the chemosensitivity of gastric cancer cells to cisplatin by suppressing the PI3K/AKT signaling pathway

in Pharmacology of Anti-Cancer Drugs

Yiping Wang
Hang Lv
Li Shen
Zhe Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1553791

1,346 views

Systematic Review

Published on 07 Apr 2025

A bibliometric and visual analysis based on immune checkpoint inhibitors for hepatocellular carcinoma: 2014 – 2024

in Pharmacology of Anti-Cancer Drugs

Gao-Min Liu
Rui Guo
Ji-Wei Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1520055

1,294 views

Original Research

Published on 04 Apr 2025

MicroRNA-665 and its potential role in drug response and survival outcomes in multiple myeloma: a preliminary study

in Pharmacology of Anti-Cancer Drugs

Rui Bergantim
Sara Peixoto da Silva
Vanessa Pinto
Joana M. Pereira
Diana Sousa
Fernanda Trigo
Rune Matthiesen
José E. Guimarães
M. Helena Vasconcelos

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1465814

1,268 views

Original Research

Published on 04 Apr 2025

Development and validation of hierarchical signature for precision individualized therapy based on the landscape associated with necroptosis in clear cell renal cell carcinoma

in Pharmacology of Anti-Cancer Drugs

Gao-Sheng Yao
Jun-Shang Dai
Liang-Min Fu
Juan Lin
Zhi-Ping Tan
Lei Dai
Wei Chen
Jun-Hang Luo
Jin-Huan Wei

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1470145

1,149 views

Original Research

Published on 03 Apr 2025

Norcantharidin inhibits TOP2A expression via H3K27me3 mediated epigenetic regulation to alleviate the progression of hepatocellular carcinoma

in Pharmacology of Anti-Cancer Drugs

Ruibing Wu
Hengye Yuan
Yuehua Wang
Xianggang Gou
Wanhua Hou
Zhongzheng Zhou
Xinran Wang
Xiuling Deng
Changshan Wang
Haisheng Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1541298

1,173 views

Original Research

Published on 03 Apr 2025

Synergistic anticancer potential of biogenic nanoparticles and cryptomeridiol from Sphaeranthus indicus: targeting gastric cancer through apoptosis and cell cycle arrest

in Pharmacology of Anti-Cancer Drugs

Pan Zhao
Jigang Wang
Chang Zou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1565308

1,208 views
1 citation

Original Research

Published on 03 Apr 2025

From COPD to cancer: indacaterol’s unexpected role in combating NSCLC

in Pharmacology of Anti-Cancer Drugs

Chenghao Liu
Jiaqi Huang
Pengjie Cai
Min Jiang
Honglei Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1579126

1,281 views

Original Research

Published on 02 Apr 2025

Reversal of sorafenib resistance in hepatocellular carcinoma by curcumol: insights from network pharmacology, molecular docking, and experimental validation

in Pharmacology of Anti-Cancer Drugs

Ni Zhang
Xinchen Tian
Fen Liu
Xiaohan Jin
Jiaqi Zhang
Lingli Hao
Shulong Jiang
Qingbin Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1514997

1,912 views
1 citation

Original Research

Published on 02 Apr 2025

Research mapping of cannabinoids and endocannabinoid system in cancer over the past three decades: insights from bibliometric analysis

in Pharmacology of Anti-Cancer Drugs

Yaqian Tan
Hui Xia
Qi Song

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1540619

1,187 views

Original Research

Published on 02 Apr 2025

Therapeutic potential and mechanistic insights of silibinin targeting cancer-associated fibroblasts in colorectal cancer

in Pharmacology of Anti-Cancer Drugs

Shenglan He
Jianmei Ji
Kaisi Zhu
Youlan Chen
Xiaowen Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1527871

1,043 views

Original Research

Published on 02 Apr 2025

Discovery of benzethonium chloride as a potent STAT3 inhibitor for the treatment of HNSCC

in Pharmacology of Anti-Cancer Drugs

Yuefeng Han
Shumin Li
Deshang Chen
Mingjie Zhang
Guoying Han
QianQian Xu
Xianming Ge
Mengli Wang
Yan Pan
Sien Ma

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1569570

1,220 views

Original Research

Published on 01 Apr 2025

New prognostic features and personalized treatment strategies of mitochondrial related genes in colorectal cancer patients

in Pharmacology of Anti-Cancer Drugs

Qizheng Xu
Zhiwen Wang
Shan-Tao Huang
Jia-Yu Shi
Yan Zhu
Han-Qing Pang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1540767

1,355 views