Frontiers in Pharmacology | Pharmacology of Anti-Cancer Drugs

Original Research

Published on 21 Feb 2025

Adverse drug reactions to atezolizumab in combination with bevacizumab in hepatocellular carcinoma patients: an analysis of the food and drug administration adverse event reporting system database

in Pharmacology of Anti-Cancer Drugs

Wanming He
Lihua Tong
Yanling Yuan
Xia Yang
Wen Yang
Xingxi Pan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1448095

2,174 views

Original Research

Published on 21 Feb 2025

Elucidation of Callistemon lanceolatus-derived natural compounds in STAT 3 pathway against human cancer cells: in silico and in vitro studies

in Pharmacology of Anti-Cancer Drugs

Mubashir Zafar
Sadaf Anwar
Malik Asif Hussain
Naveed Iqbal
Abrar Ali
Sadaf
Mohammad Zeeshan Najm
Mohd Adnan Kausar

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1507002

958 views

Review

Published on 20 Feb 2025

Hepatotoxicity induced by arsenic trioxide: clinical features, mechanisms, preventive and potential therapeutic strategies

in Pharmacology of Anti-Cancer Drugs

Jun Wen
Aiwen Li
Ziliang Wang
Xiaoxiao Guo
Gaoling Zhang
Mark R. Litzow
Qiuju Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1536388

1,525 views

Review

Published on 20 Feb 2025

Sesquiterpene lactones and cancer: new insight into antitumor and anti-inflammatory effects of parthenolide-derived Dimethylaminomicheliolide and Micheliolide

in Pharmacology of Anti-Cancer Drugs

Jian Li
Xin Li
Hongwei Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1551115

1,107 views

Case Report

Published on 20 Feb 2025

Disitamab vedotin combined with pyrotinib as salvage treatment in Her-2-amplified treatment refractory metastatic colorectal cancer: a case report

in Pharmacology of Anti-Cancer Drugs

Jianxin Chen
Jian Wang
Qinhong Zheng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1431422

985 views

Original Research

Published on 20 Feb 2025

β-lapachone suppresses carcinogenesis of cervical cancer via interaction with AKT1

in Pharmacology of Anti-Cancer Drugs

Pan Du
Yue Li
Anna Han
Mengying Wang
Jiajing Liu
Yingshi Piao
Liyan Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1509568

1,412 views
1 citation

Case Report

Published on 19 Feb 2025

Case report: Pharmacokinetic interaction involving sirolimus and regorafenib in patients with post-transplant recurrent hepatocellular carcinoma

in Pharmacology of Anti-Cancer Drugs

Kongcai Zhu
Fang Xiong
Haihong Bai
Wei Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1472896

821 views
1 citation

Original Research

Published on 19 Feb 2025

Uncovering potential targets for antibody-drug conjugates in the treatment of gynecologic malignancies

in Pharmacology of Anti-Cancer Drugs

Yuying Jiang
Yuance Xu
Junqi He
Lei Sui
Tian Li
Nannan Xia
Qin Yao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1525733

2,220 views

Original Research

Published on 19 Feb 2025

Integration of multi-omics profiling reveals an epigenetic-based molecular classification of lung adenocarcinoma: implications for drug sensitivity and immunotherapy response prediction

in Pharmacology of Anti-Cancer Drugs

Ning Wang
Yinan Li
Yaoyao Wang
Wenting Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1540477

1,386 views

Original Research

Published on 19 Feb 2025

Dual inhibitor of MDM2 and NFAT1 for experimental therapy of breast cancer: in vitro and in vivo anticancer activities and newly discovered effects on cancer metabolic pathways

in Pharmacology of Anti-Cancer Drugs

Wei Wang
Marlene Aguilar
Sayantap Datta
Abigail Alley
Meheret Tadesse
Xinshi Wang
Xia Gao
Ruiwen Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1531667

1,858 views

Original Research

Published on 18 Feb 2025

Exploring the role of epigenetic regulation in cancer prognosis with epigenetic score

in Pharmacology of Anti-Cancer Drugs

Ruiguang Zhang
Shimin Jin
Qi Xu
Rongxiao Dai

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1538205

1,126 views

Correction

Published on 18 Feb 2025

Corrigendum: The role of epigenetic regulation in pancreatic ductal adenocarcinoma progression and drug response: an integrative genomic and pharmacological prognostic prediction model

in Pharmacology of Anti-Cancer Drugs

Kang Fu
Junzhe Su
Yiming Zhou
Xiaotong Chen
Xiao Hu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1560529

630 views

Review

Published on 18 Feb 2025

Potential mechanism of traditional Chinese medicine intervention in gastric cancer: targeted regulation of autophagy

in Pharmacology of Anti-Cancer Drugs

Siyuan Sun
Wenqian Yu
Guangheng Zhang
Xiangyu Li
Linjing Song
Yehan Lv
Yi Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1548672

2,888 views
3 citations

Original Research

Published on 18 Feb 2025

ASF1B promotes gastric cancer progression by modulating H2AC20 and activating PI3K/AKT and ERK1/2 pathways

in Pharmacology of Anti-Cancer Drugs

Mengyuan Zhao
Junchang Zhang
Yanjun He
Chongge You

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1533257

1,471 views

Review

Published on 17 Feb 2025

Regulatory role and therapeutic prospect of lactate modification in cancer

in Pharmacology of Anti-Cancer Drugs

Mengdi Sun
Kejing Wang
Fang Lu
Donghua Yu
Shumin Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1508552

4,005 views

Case Report

Published on 14 Feb 2025

Case report: Aumolertinib plus gumarontinib in a patient with EGFR mutated non-small-cell lung cancer harboring acquired MET amplification following progression on afatinib plus crizotinib

in Pharmacology of Anti-Cancer Drugs

Jia-Jun Hui
Sheng-Jun Ding
Bao-Dong Qin
Ning Ding

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1525251

1,366 views