Frontiers in Pharmacology | Pharmacology of Anti-Cancer Drugs

Review

Accepted on 28 Jul 2025

Nanoengineered-Based Delivery Systems to Modulate CD4⁺ T Cell Responses in Cancer: Emerging Paradigms in Cancer Immunotherapy

in Pharmacology of Anti-Cancer Drugs

Nekhat Shahreen
Anukrati Agnihotri
Asfi Rizwan
Faizul Hasan
Mohd Danish Ansari
Zarif Mohamed Sofian
Nur Akmarina Mohd Said
Kenneth KW To
Syed Mahmood

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1643791

Original Research

Published on 28 Jul 2025

Doxorubicin delivery by pYEEIE peptide-functionalized rhodiola rosea-derived exosome-like nanovesicles for targeted melanoma therapy

in Pharmacology of Anti-Cancer Drugs

Meitao Duan
Binbin Chen
Xue Yi
Ahmed Mahal
Linwei Song
Moxun Xu
Ahmad J. Obaidullah
Shuwei Yu
Chen Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1619998

244 views

Systematic Review

Published on 28 Jul 2025

The protective role of curcumin in mitigating drug-induced toxicity in male reproductive system

in Pharmacology of Anti-Cancer Drugs

Mitra Tarlan
Shabnam Moradi
Niloofar Heidarizade
Omid Tavallaei
Saeed Khazayel
Mohamad Hosein Farzaei
Javier Echeverría

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1620732

164 views

Case Report

Accepted on 25 Jul 2025

Immune-Related Eruptive Keratoacanthoma with Fungal Coinfection Under PD-1 Inhibitor Therapy: A Diagnostic and Therapeutic Challenge

in Pharmacology of Anti-Cancer Drugs

Yingjie Su
Zheng Wu
Yanli Hou
Mengxia Yan
Xiumei Ma
Houwen Lin

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1619450

Data Report

Accepted on 25 Jul 2025

OncoAID: An Open Access Targeted Anti-Cancer Drugs Database

in Pharmacology of Anti-Cancer Drugs

Ohad Landau
Shai Magidi
Catherine Bresson
Fanny Wunder
Razelle Kurzrock
Wafik S El- Deiry
Kartheeswaran Thangathurai
Eitan Rubin

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1588191

234 views

Review

Published on 25 Jul 2025

CXCR3 inhibitors for therapeutic interventions: current status and perspectives

in Pharmacology of Anti-Cancer Drugs

Rongrong Huo
Yu Jiang
Li Zhang
Shufang Du
Dan Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1556196

314 views

Systematic Review

Published on 25 Jul 2025

Comparative long-term outcomes of first-line CDK4/6 inhibitors plus endocrine therapy versus endocrine therapy in patients with HR+/HER2-metastatic or advanced breast cancer: a meta-analysis

in Pharmacology of Anti-Cancer Drugs

Xiaojian Wang
Xinyi Liang
Chenchen Li
Mengtian Qin
Jianyu Wu
Yuechen Qin
Yue Zou
Haijian Zeng
Chunlan Li
Xiaomeng Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1600892

285 views

Original Research

Published on 25 Jul 2025

Targeting PGK1 as a Novel strategy to regulate the sensitivity of HER2 positive gastric cancer to lapatinib

in Pharmacology of Anti-Cancer Drugs

Xiaochen Ni
Kaiyuan Zhang
Xueru Huang
Mingsi Zhang
Jianing Guo
Wei Fan
Chuhang Wang
Zhongyan Du
Tao Jiang
Guangji Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1530492

191 views

Original Research

Published on 25 Jul 2025

Spatial deciphering of the transcriptomic heterogeneity of tumor spread through air spaces in lung cancer

in Pharmacology of Anti-Cancer Drugs

Wenhao Wang
Wenhao Zhou
Jingli Fan
Tao Jiang
Guang Yang
Congcong Song
Siwei Xu
Haitao Luo
Huining Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1567527

329 views

Original Research

Published on 24 Jul 2025

BCL6 promotes the progression of high-grade serous ovarian cancer cells by inhibiting PLAAT4

in Pharmacology of Anti-Cancer Drugs

An Wan
Wei-Dong Zhao
Gang Chen
Cheng Peng
Jin-Hui Tao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1634995

349 views

Original Research

Published on 24 Jul 2025

Inhibition of SIRT3 by a specific inhibitor induces cellular senescence and growth arrest of ovarian granulosa cell tumor via p53 and NF-κB axis

in Pharmacology of Anti-Cancer Drugs

Jingxin Ma
Sailing Lin
Chuimian Zeng
Wenhao Wu
Qi Zhang
Guli Zhu
Qi Zhang
Qiongfang Fang
Lijun Fan
Shunichi Takeda

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1608156

331 views

Original Research

Published on 23 Jul 2025

CDFA: Calibrated deep feature aggregation for screening synergistic drug combinations

in Pharmacology of Anti-Cancer Drugs

Xiaorui Kang
Xiaoyan Liu
Quan Zou
Tiantian Li
Ximei Luo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1608832

370 views

Review

Published on 23 Jul 2025

The role of ubiquitination and deubiquitination in urological tumours

in Pharmacology of Anti-Cancer Drugs

Lifeng Gan
Peiyue Luo
Junrong Zou
Wei Li
Qi Chen
Le Cheng
Fangtao Zhang
Haidong Zhong
Liying Zheng
Biao Qian

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1532878

256 views

Original Research

Published on 23 Jul 2025

Emerging trends and knowledge networks in pan-cancer sorafenib resistance: a 20-year bibliometric investigation

in Pharmacology of Anti-Cancer Drugs

Qiong Zhou
Rui Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1581820

358 views

Case Report

Published on 23 Jul 2025

Case Report: Tislelizumab-induced insulin-dependent diabetes mellitus: a case report and literature review

in Pharmacology of Anti-Cancer Drugs

Panpan Ji
Yahui Zhang
Wen Zhang
Bing Leng
Ruifang Nie
Chengwu Shen
Hengcai Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1499796

382 views

Original Research

Published on 23 Jul 2025

Phosphoglycerate kinase 1 as a potential prognostic biomarker in papillary thyroid carcinoma

in Pharmacology of Anti-Cancer Drugs

Xiao-Qing Shi
Xiao-Tong Liu
Xiao-Hui Liu
Hui-Wen Geng
Zhuo Zhang
Wei-Yi Wang
Xing Chen
Xian Zhao
Bo-Lin Jue
Bo Qin

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1542159

272 views