Frontiers in Pharmacology | Pharmacology of Anti-Cancer Drugs

Original Research

Published on 02 Apr 2025

Therapeutic potential and mechanistic insights of silibinin targeting cancer-associated fibroblasts in colorectal cancer

in Pharmacology of Anti-Cancer Drugs

Shenglan He
Jianmei Ji
Kaisi Zhu
Youlan Chen
Xiaowen Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1527871

187 views

Original Research

Published on 02 Apr 2025

Discovery of benzethonium chloride as a potent STAT3 inhibitor for the treatment of HNSCC

in Pharmacology of Anti-Cancer Drugs

Yuefeng Han
Shumin Li
Deshang Chen
Mingjie Zhang
Guoying Han
QianQian Xu
Xianming Ge
Mengli Wang
Yan Pan
Sien Ma

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1569570

221 views

Original Research

Accepted on 01 Apr 2025

Elucidation of the Mechanism Underlying the Promotion of ferroptosis and Enhanced Antitumor Immunity by Citrus Polymethoxyflavones in CRC Cells

in Pharmacology of Anti-Cancer Drugs

SENLING FENG
Yingying Duan
Yu Wu
Jiaqi Tian
Yuqin Yin
Zhongwen Yuan
Wenting Zhu
Suyue Zhou
Chen Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1571178

Original Research

Published on 01 Apr 2025

New prognostic features and personalized treatment strategies of mitochondrial related genes in colorectal cancer patients

in Pharmacology of Anti-Cancer Drugs

Qizheng Xu
Zhiwen Wang
Shan-Tao Huang
Jia-Yu Shi
Yan Zhu
Han-Qing Pang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1540767

171 views

Original Research

Published on 01 Apr 2025

Exploring the impact of cuproptosis on prostate cancer prognosis via RNA methylation regulation based on single cell and bulk RNA sequencing data

in Pharmacology of Anti-Cancer Drugs

Junchao Wu
Wentian Wu
Jiaxuan Qin
Ziqi Chen
Rongfang Zhong
Peng Guo
Song Fan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1573611

202 views

Systematic Review

Published on 01 Apr 2025

Efficacy and safety of tirabrutinib monotherapy in relapsed or refractory B-cell lymphomas/leukemia: a meta-analysis

in Pharmacology of Anti-Cancer Drugs

Jingfei Wang
Hai-en Cheng
Yanhua Sun
Zhenfeng Li
Yunke Zang
Yuying Zhao
Guimao Yang
Zhijun Liu
Yaqi Sun
Yanli Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1559056

288 views

Case Report

Published on 01 Apr 2025

Case Report: Second-line favourable effect of pembrolizumab plus chemotherapy in a patient with metastatic hepatoid adenocarcinoma of the stomach

in Pharmacology of Anti-Cancer Drugs

Yao Tang
Xiaofen Li
Yu Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1387661

132 views

Systematic Review

Accepted on 31 Mar 2025

Global trends in resistance studies of gemcitabine and pancreatic cancer: a bibliometric and visual analysis from 2010 to 2024

in Pharmacology of Anti-Cancer Drugs

Dandan Gu
Shaoyang Huang
Kai Zhao
Xiaohong Zhang
Jinjing Zhang
Wei Xiong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1564561

Original Research

Accepted on 31 Mar 2025

SUMOylation substrate encoding genesRelated Genes as Prognostic Biomarkers in Pancreatic Ductal Adenocarcinoma with Functional Assessment of SAF-B2

in Pharmacology of Anti-Cancer Drugs

Xiangjun Wang
Chuanxin Yang
Yangming Liu
Jian Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1532658

Review

Accepted on 31 Mar 2025

SREBP2 as a central player in cancer progression: potential for targeted therapeutics

in Pharmacology of Anti-Cancer Drugs

Ruiqi Chen
Tianyu Chen
Xiang Li
Junfeng Yu
Min Lin
Siqi Wen
Man Zhang
Jinchi Chen
Bei Yi
Huage Zhong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1535691

Original Research

Accepted on 31 Mar 2025

Targeting PCNA/PARP1 axis inhibits the malignant progression of hepatocellular carcinoma

in Pharmacology of Anti-Cancer Drugs

Jipin Li
Tao Yong
Yali Chen
Tingyu Zeng
Kaifeng Zhang
Shuping Wang
Youcheng Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1571786

Original Research

Accepted on 31 Mar 2025

Dehydroleucodine Exerts an Antiproliferative Effect on Human Burkitt's Lymphoma Daudi Cells via SLC7A11-mediated Ferroptosis

in Pharmacology of Anti-Cancer Drugs

Rui Shen
Fang Cheng
Rui Guo
Wenjing Wang
Xiaolong Yang
Yemiao CHEN
Yaokai Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1572364

Original Research

Accepted on 28 Mar 2025

Pan-cancer analysis identified CD248 as a potential target for multiple tumor types

in Pharmacology of Anti-Cancer Drugs

Li Guo
Yan Liao
Xuyang Zhang
Rongjuan Guo
Zheng Wang
Deqin Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1554632

Review

Published on 28 Mar 2025

The multiple functions and mechanisms of long non-coding RNAs in regulating breast cancer progression

in Pharmacology of Anti-Cancer Drugs

Yongsheng Zhang
Yanjiao Xu
Yanping Zhang
Shoushi Wang
Mingqiang Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1559408

157 views

Review

Published on 28 Mar 2025

The potential of dibenzazepine carboxamides in cancer therapy

in Pharmacology of Anti-Cancer Drugs

Nastaran Afsordeh
Safura Pournajaf
Javad Mirnajafi-Zadeh
Mohammad Hossein Pourgholami

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1564911

253 views

Original Research

Published on 28 Mar 2025

Schisandrin B downregulates exosomal fibronectin 1 expression to inhibit hepatocellular carcinoma growth

in Pharmacology of Anti-Cancer Drugs

Baoyi Jiang
Jie Yang
Qingtian Huang
Wei Li
Qian Peng
Huoye Gan
Tieli Peng
Leyi Yao
Ling Qi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1547685

176 views