Frontiers in Pharmacology | Pharmacology of Infectious Diseases

Original Research

Published on 16 Dec 2022

Pharmacokinetics/pharmacodynamics of polymyxin B in patients with bloodstream infection caused by carbapenem-resistant Klebsiella pneumoniae

in Pharmacology of Infectious Diseases

Zhenwei Yu
Xiaofen Liu
Xiaoxing Du
Huiying Chen
Feng Zhao
Zhihui Zhou
Yu Wang
Yang Zheng
Phillip J. Bergen
Xi Li

Frontiers in Pharmacology

doi 10.3389/fphar.2022.975066

7,197 views
19 citations

Original Research

Published on 13 Dec 2022

Cell cycle block by p53 activation reduces SARS-CoV-2 release in infected alveolar basal epithelial A549-hACE2 cells

in Pharmacology of Infectious Diseases

Giada Lodi
Valentina Gentili
Fabio Casciano
Arianna Romani
Giorgio Zauli
Paola Secchiero
Enrico Zauli
Carolina Simioni
Silvia Beltrami
Mercedes Fernandez

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1018761

4,770 views
10 citations

Clinical Trial

Published on 12 Dec 2022

A randomized, double-blind, placebo-controlled phase I trial of inhalation treatment of recombinant TFF2-IFN protein: A multifunctional candidate for the treatment of COVID-19

in Pharmacology of Infectious Diseases

Yan Liu
Guanxing Zhai
Weihui Fu
Xiaoyan Zhang
Jianqing Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1063106

2,454 views
2 citations

Original Research

Published on 12 Dec 2022

Cerebrospinal fluid concentrations of fluoroquinolones and carbapenems in tuberculosis meningitis

in Pharmacology of Infectious Diseases

Nicole F. Maranchick
Mohammad H. Alshaer
Alison G. C. Smith
Teona Avaliani
Mariam Gujabidze
Tinatin Bakuradze
Shorena Sabanadze
Zaza Avaliani
Maia Kipiani
Charles A. Peloquin

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1048653

8,682 views
19 citations

Review

Published on 09 Dec 2022

Pharmacokinetics and pharmacodynamics of anti-tuberculosis drugs: An evaluation of in vitro, in vivo methodologies and human studies

in Pharmacology of Infectious Diseases

Jan-Willem C. Alffenaar
Jurriaan E. M. de Steenwinkel
Andreas H. Diacon
Ulrika S. H. Simonsson
Shashikant Srivastava
Sebastian G. Wicha

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1063453

13,049 views
28 citations

Original Research

Published on 01 Dec 2022

PKHB1 peptide induces antiviral effects through induction of immunogenic cell death in herpes simplex keratitis

in Pharmacology of Infectious Diseases

Yun He
Chenchen Wang
Qi Liang
Rongjie Guo
Jiaxuan Jiang
Wenhao Shen
Kai Hu

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1048978

5,643 views
15 citations

Original Research

Published on 30 Nov 2022

Prenylated phenolics from Morus alba against MRSA infections as a strategy for wound healing

in Pharmacology of Infectious Diseases

Gabriela Škovranová
Marie Čulenová
Jakub Treml
Lucia Dzurická
Ivana Marova
Alice Sychrová

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1068371

5,246 views
13 citations

Original Research

Published on 30 Nov 2022

Optimizing antimicrobial therapy in urinary tract infections: A focus on urine culture and sensitivity testing

in Pharmacology of Infectious Diseases

Rama Alkhawaldeh
Rana Abu Farha
Khawla Abu Hammour
Eman Alefishat

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1058669

6,754 views
18 citations

Review

Published on 30 Nov 2022

Selective serotonin reuptake inhibitors: New hope in the fight against COVID-19

in Pharmacology of Infectious Diseases

Mahsa Asadi Anar
Elaheh Foroughi
Elika Sohrabi
Samira Peiravi
Yasaman Tavakoli
Mozhgan Kameli Khouzani
Parisa Behshood
Melika Shamshiri
Arezoo Faridzadeh
Kimia Keylani

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1036093

16,259 views
8 citations

Original Research

Published on 24 Nov 2022

Appraisal of selected ethnomedicinal plants as alternative therapies against onychomycosis: Evaluation of synergy and time-kill kinetics

in Pharmacology of Infectious Diseases

Syeda Aroosa Mohsin
Shazia Shaukat
Marya Nawaz
Tofeeq Ur-Rehman
Nadeem Irshad
Muhammad Majid
Syed Shams ul Hassan
Simona Bungau
Humaira Fatima

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1067697

5,422 views
9 citations

Opinion

Published on 16 Nov 2022

Immunopathogenesis in SARS-CoV-2 and Mycobacterium tuberculosis: The danger of overlapping crises

in Pharmacology of Infectious Diseases

Prakasini Satapathy
Radha Kanta Ratho
Sunil Sethi

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1065124

2,295 views
2 citations

Original Research

Published on 14 Nov 2022

Pharmacodynamic evaluation of lefamulin in the treatment of gonorrhea using a hollow fiber infection model simulating Neisseria gonorrhoeae infections

in Pharmacology of Infectious Diseases

Susanne Jacobsson
Daniel Golparian
Joakim Oxelbark
Wolfgang W. Wicha
Renata Maria Augusto da Costa
Francois Franceschi
David Brown
Arnold Louie
Steven P. Gelone
George Drusano

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1035841

4,455 views
21 citations

Original Research

Published on 11 Nov 2022

Common recognition topology of mex transporters of Pseudomonas aeruginosa revealed by molecular modelling

in Pharmacology of Infectious Diseases

Andrea Catte
Venkata K. Ramaswamy
Attilio Vittorio Vargiu
Giuliano Malloci
Andrea Bosin
Paolo Ruggerone

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1021916

3,752 views
7 citations

Original Research

Published on 11 Nov 2022

Evaluation of vancomycin pharmacokinetics in patients with augmented renal clearances: A randomized clinical trial

in Pharmacology of Infectious Diseases

Zahra Sahraei
Ali Saffaei
Ilad Alavi Darazam
Jamshid Salamzadeh
Minoosh Shabani
Shervin Shokouhi
Najmeh Sarvmeili
Mohammadreza Hajiesmaeili
Masood Zangi

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1041152

5,760 views
8 citations

Review

Published on 11 Nov 2022

Review of preclinical data of PF-07304814 and its active metabolite derivatives against SARS-CoV-2 infection

in Pharmacology of Infectious Diseases

Wujun Chen
Yingchun Shao
Xiaojin Peng
Bing Liang
Jiazhen Xu
Dongming Xing

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1035969

5,939 views
14 citations

Opinion

Published on 08 Nov 2022

Emerging pneumonia-like illness “legionellosis” in Argentina in the COVID-19 era: Cause to panic?

in Pharmacology of Infectious Diseases

Ranjan K. Mohapatra
Ahmed Mahal
Venkataramana Kandi
L. V. Simhachalam Kutikuppala
Ashish K. Sarangi
Snehasish Mishra

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1063237

2,746 views
1 citation

Original Research

Published on 08 Nov 2022

The effect of Nigella sativa and vitamin D3 supplementation on the clinical outcome in COVID-19 patients: A randomized controlled clinical trial

in Pharmacology of Infectious Diseases

Shimaa A. Said
Alsayyed Abdulbaset
Amal A. El-Kholy
Osama Besckales
Nagwa A. Sabri

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1011522

12,546 views
19 citations

Review

Published on 08 Nov 2022

Nanodelivery of antiretroviral drugs to nervous tissues

in Pharmacology of Infectious Diseases

Sodiq Kolawole Lawal
Samuel Oluwaseun Olojede
Oluwaseun Samuel Faborode
Okikioluwa Stephen Aladeyelu
Matome Nadab Matshipi
Sheu Oluwadare Sulaiman
Edwin Coleridge Stephen Naidu
Carmen Olivia Rennie
Onyemaechi Okpara Azu

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1025160

4,791 views
7 citations

Original Research

Published on 03 Nov 2022

The recommended dosage regimen for caspofungin in patients with higher body weight or hypoalbuminaemia will result in low exposure: Five years of data based on a population pharmacokinetic model and Monte-Carlo simulations

in Pharmacology of Infectious Diseases

Qianting Yang
Tao Zhang
Ying Zhang
Dan Sun
Xiaowei Zheng
Qian Du
Xue Wang
Xiaoliang Cheng
Jianfeng Xing
Yalin Dong

Frontiers in Pharmacology

doi 10.3389/fphar.2022.993330

6,049 views
10 citations

Review

Published on 31 Oct 2022

Synthetic approaches to potent heterocyclic inhibitors of tuberculosis: A decade review

in Pharmacology of Infectious Diseases

Upala Dasmahapatra
Kaushik Chanda

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1021216

9,182 views
7 citations

Original Research

Published on 25 Oct 2022

Berberine prevents lethal EV71 neurological infection in newborn mice

in Pharmacology of Infectious Diseases

Guangyi Cui
Han Wang
Chongting Yang
Xiaoxiao Zhou
Junyi Wang
Tong Wang
Tonghui Ma

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1027566

5,115 views
21 citations

Review

Published on 21 Oct 2022

Polyphenolic promiscuity, inflammation-coupled selectivity: Whether PAINs filters mask an antiviral asset

in Pharmacology of Infectious Diseases

Rick Sheridan
Kevin Spelman

Frontiers in Pharmacology

doi 10.3389/fphar.2022.909945

5,400 views
16 citations

Original Research

Published on 20 Oct 2022

Genotype-phenotype association and biochemical analyses of glucose-6-phosphate dehydrogenase variants: Implications for the hemolytic risk of using 8-aminoquinolines for radical cure

in Pharmacology of Infectious Diseases

Sirapapha Sudsumrit
Kamonwan Chamchoy
Duantida Songdej
Poom Adisakwattana
Srivicha Krudsood
Emily R. Adams
Mallika Imwong
Ubolsree Leartsakulpanich
Usa Boonyuen

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1032938

4,094 views
4 citations

Original Research

Published on 18 Oct 2022

Minocycline intra-bacterial pharmacokinetic hysteresis as a basis for pharmacologic memory and a backbone for once-a-week pan-tuberculosis therapy

in Pharmacology of Infectious Diseases

Devyani Deshpande
Shashikant Srivastava
Jotam Garaimunashe Pasipanodya
Tawanda Gumbo

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1024608

3,133 views
1 citation

439 articles

articles

Pharmacokinetics/pharmacodynamics of polymyxin B in patients with bloodstream infection caused by carbapenem-resistant Klebsiella pneumoniae

Cell cycle block by p53 activation reduces SARS-CoV-2 release in infected alveolar basal epithelial A549-hACE2 cells

A randomized, double-blind, placebo-controlled phase I trial of inhalation treatment of recombinant TFF2-IFN protein: A multifunctional candidate for the treatment of COVID-19

Cerebrospinal fluid concentrations of fluoroquinolones and carbapenems in tuberculosis meningitis

Pharmacokinetics and pharmacodynamics of anti-tuberculosis drugs: An evaluation of in vitro, in vivo methodologies and human studies

PKHB1 peptide induces antiviral effects through induction of immunogenic cell death in herpes simplex keratitis

Prenylated phenolics from Morus alba against MRSA infections as a strategy for wound healing

Optimizing antimicrobial therapy in urinary tract infections: A focus on urine culture and sensitivity testing

Selective serotonin reuptake inhibitors: New hope in the fight against COVID-19

Appraisal of selected ethnomedicinal plants as alternative therapies against onychomycosis: Evaluation of synergy and time-kill kinetics

Immunopathogenesis in SARS-CoV-2 and Mycobacterium tuberculosis: The danger of overlapping crises

Pharmacodynamic evaluation of lefamulin in the treatment of gonorrhea using a hollow fiber infection model simulating Neisseria gonorrhoeae infections

Common recognition topology of mex transporters of Pseudomonas aeruginosa revealed by molecular modelling

Evaluation of vancomycin pharmacokinetics in patients with augmented renal clearances: A randomized clinical trial

Review of preclinical data of PF-07304814 and its active metabolite derivatives against SARS-CoV-2 infection

Emerging pneumonia-like illness “legionellosis” in Argentina in the COVID-19 era: Cause to panic?

The effect of Nigella sativa and vitamin D3 supplementation on the clinical outcome in COVID-19 patients: A randomized controlled clinical trial

Nanodelivery of antiretroviral drugs to nervous tissues

The recommended dosage regimen for caspofungin in patients with higher body weight or hypoalbuminaemia will result in low exposure: Five years of data based on a population pharmacokinetic model and Monte-Carlo simulations

Synthetic approaches to potent heterocyclic inhibitors of tuberculosis: A decade review

Berberine prevents lethal EV71 neurological infection in newborn mice

Polyphenolic promiscuity, inflammation-coupled selectivity: Whether PAINs filters mask an antiviral asset

Genotype-phenotype association and biochemical analyses of glucose-6-phosphate dehydrogenase variants: Implications for the hemolytic risk of using 8-aminoquinolines for radical cure

Minocycline intra-bacterial pharmacokinetic hysteresis as a basis for pharmacologic memory and a backbone for once-a-week pan-tuberculosis therapy