Frontiers in Pharmacology | Pharmacology of Infectious Diseases

Opinion

Published on 24 Oct 2025

Green-synthesized silver nanoparticle hydrogels for biofilm-infected wounds: Bridging sustainability and clinical translation

in Pharmacology of Infectious Diseases

M. Rifqi Fadillah Muslim
Lutfi Chabib
Betty Ekawati Suryaningsih
Farida Hayati
Viviane Annisa

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1694144

1,257 views
1 citation

Original Research

Published on 17 Oct 2025

GEODE: an in silico tool that translates in vitro to in vivo predictions of tuberculosis antibiotic combination efficacy

in Pharmacology of Infectious Diseases

Maral Budak
Mariana Pereira Moraes
Talia Greenstein
Pauline Maiello
H. Jacob Borish
Harris B. Chishti
Kara Kracinovsky
Mark Rodgers
Jaime Tomko
Philana Ling Lin

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1639673

2,243 views

Editorial

Published on 14 Oct 2025

Editorial: Multidrug resistant bacteria: new therapeutic approaches for a challenging problem

in Pharmacology of Infectious Diseases

Gabriela C. Fernández
Younes Smani
Sonia A. Gómez

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1712353

1,081 views

Original Research

Published on 10 Oct 2025

Optimizing antifungal dosing for invasive Cryptococcus infections: minimum inhibitory concentration distributions and pharmacokinetic/pharmacodynamic insights from 2010–2023 Antimicrobial Testing Leadership and Surveillance data

in Pharmacology of Infectious Diseases

Chia-Ying Liu
Chih-Cheng Lai
Chun-Chung Hsueh
Chih-Jen Weng
Wei-Lun Chang
Po-Ren Hsueh
Shio-Shin Jean

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1665253

1,773 views

Study Protocol

Published on 08 Oct 2025

Yiqi Gubiao Pill for tuberculosis-associated obstructive pulmonary disease: protocol for a double-blind randomized controlled trial

in Pharmacology of Infectious Diseases

Jin Dai
Yifan Zhang
Jun Su
Guoxiang Yuan
Fengsen Li
Zhian Zhou
Aziza
Chunying Ye
Aznamu Seyiti
Maihesebu Pida

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1610889

1,705 views

Review

Published on 30 Sep 2025

Evaluating the advancements and efficacies in pharmacological Mpox treatments: a comprehensive review

in Pharmacology of Infectious Diseases

Shuaibu Abdullahi Hudu
Najlaa Saadi
Albashir Tahir
Abdulgafar Olayiwola Jimoh
Aliyu Haruna

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1654467

2,964 views

Original Research

Published on 30 Sep 2025

Antimicrobial activity of β-lactam antibiotics against pneumococcal isolates causing pneumococcal disease in adults immediately before and after the COVID-19 pandemic in Spain (2019–2020)

in Pharmacology of Infectious Diseases

Mirella Llamosí
Covadonga Pérez-García
Aída Úbeda
Erick J. Vidal-Alcántara
Inés Pareja-Cerbán
Elena Gómez-Rubio
Pilar Coronel
Juan Carlos Sanz
Mirian Domenech
Julio Sempere

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1658431

1,897 views

Review

Published on 29 Sep 2025

Antibiotic-sparing strategies for multidrug-resistant organism (MDRO) infections

in Pharmacology of Infectious Diseases

Shuai Geng
Qing Tang
Ning Shi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1653424

4,166 views

Review

Published on 26 Sep 2025

Small nucleic acid drugs-the dawn of functional cure of chronic hepatitis B

in Pharmacology of Infectious Diseases

Lu Zhang
Yu Cao
Sijing Zhuang
Jingjing Sun
Qiao Tong
Jianjun Xi
Shourong Liu
Rangxiao Zhuang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1633001

4,676 views

Original Research

Published on 25 Sep 2025

Topical delivery of meropenem via spanlastic carbopol gel: in-vitro studies and in-vivo application in pressure ulcers

in Pharmacology of Infectious Diseases

Shadwa Abdelfattah
Fatma Mohamed Mady
Hatem A. Sarhan
Hazim O. Khalifa
Hamada Hashem
Hesham Hassan
Abdullah Alkhammash
Safy Hadiya
Reham Ali Ibrahem
Milad Reda Qelliny

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1672677

2,394 views

Review

Published on 24 Sep 2025

Genomic variability and immunological aspects involved in response to MPXV infection

in Pharmacology of Infectious Diseases

Simone La Frazia
Anna Rosa Garbuglia
Silvia Pauciullo
Verdiana Zulian
Paola Del Porto

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1665830

3,337 views

Original Research

Published on 23 Sep 2025

β-tricalcium phosphate/calcium sulfate loaded with contezolid acefosamil (MRX-4) for antimicrobial potency, prevention and killing efficacy of MRSA biofilm

in Pharmacology of Infectious Diseases

Nan Jiang
Xin Zhang
Zi-Xian Liu
Hao-Yang Wan
Mou-Zhang Huang
Qing-Rong Lin
Guan-Qiao Liu
Peng Chen
Bin Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1657099

2,354 views

Original Research

Published on 11 Sep 2025

The role of curcumin in modulating nutritional status and susceptibility to Mycoplasma pneumoniae infection in children

in Pharmacology of Infectious Diseases

Chun-Jing Liu
Wei Liu
Hong-Xiu Yang
Li-Hua Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1651875

1,834 views

Original Research

Published on 11 Sep 2025

Antibacterial and wound healing effects of PEG-coated ciprofloxacin-loaded ZIF-8 nanozymes against ciprofloxacin-resistant Pseudomonas aeruginosa taken from burn wounds

in Pharmacology of Infectious Diseases

Mohadeseh Pahlevani
Masoumeh Beig
Seyed Mahmoud Barzi
Milad Sadeghzadeh
Morvarid Shafiei
Mohsen Chiani
Aria Sohrabi
Mohammad Sholeh
Shaghayegh Nasr

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1556335

2,620 views
1 citation

Original Research

Published on 10 Sep 2025

Real-world correlation between therapeutic drug monitoring and clinical outcomes of the antifungal drug posaconazole: a single-center retrospective cohort study

in Pharmacology of Infectious Diseases

Qiaoyan Yi
Lin Dong
Peng Wang
Yinping Shi
Yilei Yang
Zhonghua Dong
Siwen Li
Yan Li
Xin Huang
Jinjuan Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1592767

2,325 views

Editorial

Published on 10 Sep 2025

Editorial: Beyond traditional antibiotics: innovations in biologics, chemical modulators, and microbiome manipulation

in Pharmacology of Infectious Diseases

Anutthaman Parthasarathy

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1679268

1,342 views

Original Research

Published on 05 Sep 2025

Synthesis and biological activity evaluation of a novel pleuromutilin derivative 22-((2-methyl-1-(1H-pyrrole-2-carboxamido)propan-2-yl)thio)-deoxypleuromutilin

in Pharmacology of Infectious Diseases

Zhun Li
Danqian Ma
Chang Liu
Zhe Qin
Lixia Bai
Wenbo Ge
Xiao Xu
Jianyong Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1657973

1,819 views

Original Research

Published on 04 Sep 2025

Effectiveness of infection control measures informed by a modified Blue-Carba test in reducing rectal carriage of carbapenemase-producing bacteria in general wards: a prospective interrupted time series study

in Pharmacology of Infectious Diseases

Maximiliano Gabriel Castro
Fernanda Argarañá
Carla Bernasconi
Leticia Margenet
Ana Paula Amato
Joaquín Ignacio Coduri Anthonioz Blanc
Erwin Alexander Rottoli
Manuel Protto
Macarena Vicino
María José Sadonio

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1584646

2,160 views

Systematic Review

Published on 02 Sep 2025

Efficacy and safety of nebulized drugs in the treatment of non-severe mycoplasma pneumoniae pneumonia in children - a network meta-analysis

in Pharmacology of Infectious Diseases

Li Zeng
Hanlin Ye
Qiu Zhang
Ting Xu
Hong Xu
Dan Bi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1587152

3,221 views

Editorial

Published on 01 Sep 2025

Editorial: Natural products and nanotechnology: next-generation therapies for infectious diseases

in Pharmacology of Infectious Diseases

Dolores R. Serrano
Edilene Oliveira Silva
Vasundhra Bhandari

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1682331

1,304 views

Original Research

Published on 22 Aug 2025

Identification of gene signatures and potential pharmaceutical candidates linked to COVID-19-related depression based on gene expression profiles

in Pharmacology of Infectious Diseases

Shaojun Chen
Yiyuan Luo
Lihua Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1562774

1,901 views

Review

Published on 21 Aug 2025

Broad-spectrum therapeutic potential of 4-phenylbutyrate in neurological and systemic diseases of viral and non-viral origin

in Pharmacology of Infectious Diseases

Fatima Bobat
David Wu
Ethan Tu
Divya Kapoor
Pankaj Sharma
Joseph S. Adams
Chima Orameh
Tejabhiram Yadavalli
Abhijit Date
Deepak Shukla

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1621590

4,043 views

Original Research

Published on 20 Aug 2025

In vitro assessment of Brazilian red propolis against mycobacteria: antibacterial potency, synergy, inhibition of biofilm formation, and intramacrophage effects

in Pharmacology of Infectious Diseases

S. B. Martins
S. C. Teixeira
G. de Souza
Bader Y. Alhatlani
Emad M. Abdallah
S. R. Ambrosio
T. S. Silva
J. K. Bastos
M. H. Tanimoto
B. F. Barbosa

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1630134

1,946 views

Systematic Review

Published on 07 Aug 2025

Flavonoids in the treatment of Leishmania amazonensis: a review of efficacy and mechanisms

in Pharmacology of Infectious Diseases

Vinicius Lopes Lessa
Guilherme Drescher
Gustavo Gonçalves
João Carlos Baptista Lopes
Rafael Felipe da Costa Vieira
Fabiano Borges Figueiredo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1642005

2,221 views

439 articles

articles

Green-synthesized silver nanoparticle hydrogels for biofilm-infected wounds: Bridging sustainability and clinical translation

GEODE: an in silico tool that translates in vitro to in vivo predictions of tuberculosis antibiotic combination efficacy

Editorial: Multidrug resistant bacteria: new therapeutic approaches for a challenging problem

Optimizing antifungal dosing for invasive Cryptococcus infections: minimum inhibitory concentration distributions and pharmacokinetic/pharmacodynamic insights from 2010–2023 Antimicrobial Testing Leadership and Surveillance data

Yiqi Gubiao Pill for tuberculosis-associated obstructive pulmonary disease: protocol for a double-blind randomized controlled trial

Evaluating the advancements and efficacies in pharmacological Mpox treatments: a comprehensive review

Antimicrobial activity of β-lactam antibiotics against pneumococcal isolates causing pneumococcal disease in adults immediately before and after the COVID-19 pandemic in Spain (2019–2020)

Antibiotic-sparing strategies for multidrug-resistant organism (MDRO) infections

Small nucleic acid drugs-the dawn of functional cure of chronic hepatitis B

Topical delivery of meropenem via spanlastic carbopol gel: in-vitro studies and in-vivo application in pressure ulcers

Genomic variability and immunological aspects involved in response to MPXV infection

β-tricalcium phosphate/calcium sulfate loaded with contezolid acefosamil (MRX-4) for antimicrobial potency, prevention and killing efficacy of MRSA biofilm

The role of curcumin in modulating nutritional status and susceptibility to Mycoplasma pneumoniae infection in children

Antibacterial and wound healing effects of PEG-coated ciprofloxacin-loaded ZIF-8 nanozymes against ciprofloxacin-resistant Pseudomonas aeruginosa taken from burn wounds

Real-world correlation between therapeutic drug monitoring and clinical outcomes of the antifungal drug posaconazole: a single-center retrospective cohort study

Editorial: Beyond traditional antibiotics: innovations in biologics, chemical modulators, and microbiome manipulation

Synthesis and biological activity evaluation of a novel pleuromutilin derivative 22-((2-methyl-1-(1H-pyrrole-2-carboxamido)propan-2-yl)thio)-deoxypleuromutilin

Effectiveness of infection control measures informed by a modified Blue-Carba test in reducing rectal carriage of carbapenemase-producing bacteria in general wards: a prospective interrupted time series study

Efficacy and safety of nebulized drugs in the treatment of non-severe mycoplasma pneumoniae pneumonia in children - a network meta-analysis

Editorial: Natural products and nanotechnology: next-generation therapies for infectious diseases

Identification of gene signatures and potential pharmaceutical candidates linked to COVID-19-related depression based on gene expression profiles

Broad-spectrum therapeutic potential of 4-phenylbutyrate in neurological and systemic diseases of viral and non-viral origin

In vitro assessment of Brazilian red propolis against mycobacteria: antibacterial potency, synergy, inhibition of biofilm formation, and intramacrophage effects

Flavonoids in the treatment of Leishmania amazonensis: a review of efficacy and mechanisms