Frontiers in Pharmacology | Pharmacology of Ion Channels and Channelopathies

Original Research

Published on 16 Dec 2022

Ameliorative effects of omega-lycotoxin-Gsp2671e purified from the spider venom of Lycosa praegrandis on memory deficits of glutamate-induced excitotoxicity rat model

in Pharmacology of Ion Channels and Channelopathies

Mohammad Keimasi
Kowsar Salehifard
Marzieh Shahidi
Fariba Esmaeili
Noushin Mirshah Jafar Esfahani
Siamak Beheshti
Mohammadreza Amirsadri
Faezeh Naseri
Mohammadjavad Keimasi
Najmeh Ghorbani

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1048563

3,015 views
4 citations

Original Research

Published on 14 Dec 2022

Prognostic and immunological significance of calcium-related gene signatures in renal clear cell carcinoma

in Pharmacology of Ion Channels and Channelopathies

An Liu
Fei Li
Bao Wang
Le Yang
Hai Xing
Chang Su
Li Gao
Minggao Zhao
Lanxin Luo

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1055841

2,854 views
3 citations

Original Research

Published on 03 Nov 2022

Mechanisms of sympathoexcitation via P2Y6 receptors

in Pharmacology of Ion Channels and Channelopathies

Anna Mosshammer
Lifang Zou
Stefan Boehm
Klaus Schicker

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1014284

2,136 views
3 citations

Original Research

Published on 01 Nov 2022

The anticonvulsant phytocannabinoids CBGVA and CBDVA inhibit recombinant T-type channels

in Pharmacology of Ion Channels and Channelopathies

Michael Udoh
Chris Bladen
Marika Heblinski
Jia Lin Luo
Vaishali S. Janve
Lyndsey L. Anderson
Iain S. McGregor
Jonathon C. Arnold

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1048259

4,699 views
4 citations

Original Research

Published on 20 Oct 2022

Evolutionary coupling analysis guides identification of mistrafficking-sensitive variants in cardiac K+ channels: Validation with hERG

in Pharmacology of Ion Channels and Channelopathies

Yihong Zhang
Amy L. Grimwood
Jules C. Hancox
Stephen C. Harmer
Christopher E. Dempsey

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1010119

6,520 views
1 citation

Review

Published on 13 Oct 2022

Regulation of transient receptor potential channels by traditional Chinese medicines and their active ingredients

in Pharmacology of Ion Channels and Channelopathies

Shidu Yan
Yuchan Huang
Qian Xiao
Zixia Su
Lei Xia
Jinling Xie
Fan Zhang
Zhengcai Du
Xiaotao Hou
Jiagang Deng

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1039412

5,849 views
3 citations

Original Research

Published on 28 Sep 2022

ARumenamides: A novel class of potential antiarrhythmic compounds

in Pharmacology of Ion Channels and Channelopathies

Mena Abdelsayed
Dana Page
Peter C. Ruben

Frontiers in Pharmacology

doi 10.3389/fphar.2022.976903

2,408 views
3 citations

Editorial

Published on 23 Sep 2022

Editorial: Emerging perspectives in sodium channelopathies

in Pharmacology of Ion Channels and Channelopathies

J. R. Groome
H. J. Ray
M. Chahine

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1019004

1,806 views

Original Research

Published on 16 Sep 2022

Structural modeling of the hERG potassium channel and associated drug interactions

in Pharmacology of Ion Channels and Channelopathies

Jan Maly
Aiyana M. Emigh
Kevin R. DeMarco
Kazuharu Furutani
Jon T. Sack
Colleen E. Clancy
Igor Vorobyov
Vladimir Yarov-Yarovoy

Frontiers in Pharmacology

doi 10.3389/fphar.2022.966463

8,043 views
14 citations

Original Research

Published on 16 Sep 2022

Open channel block of Kv1.5 channels by HMQ1611

in Pharmacology of Ion Channels and Channelopathies

Chao Dong
Jiawei Li
Weiguang Ding
Rika Ueda
Xiaolu Xie
Jie Wu
Hiroshi Matsuura
Minoru Horie

Frontiers in Pharmacology

doi 10.3389/fphar.2022.965086

3,781 views
1 citation

Original Research

Published on 16 Sep 2022

Alkaloid ligands enable function of homomeric human α10 nicotinic acetylcholine receptors

in Pharmacology of Ion Channels and Channelopathies

Arik J. Hone
J. Michael McIntosh

Frontiers in Pharmacology

doi 10.3389/fphar.2022.981760

4,950 views
11 citations

Brief Research Report

Published on 16 Sep 2022

Apamin structure and pharmacology revisited

in Pharmacology of Ion Channels and Channelopathies

Alexey I. Kuzmenkov
Steve Peigneur
Joshua A. Nasburg
Konstantin S. Mineev
Maxim V. Nikolaev
Ernesto Lopes Pinheiro-Junior
Alexander S. Arseniev
Heike Wulff
Jan Tytgat
Alexander A. Vassilevski

Frontiers in Pharmacology

doi 10.3389/fphar.2022.977440

6,718 views
32 citations

Review

Published on 07 Sep 2022

The contribution of ion channels to shaping macrophage behaviour

in Pharmacology of Ion Channels and Channelopathies

Anna Selezneva
Alasdair J. Gibb
Dean Willis

Frontiers in Pharmacology

doi 10.3389/fphar.2022.970234

10,236 views
18 citations

Correction

Published on 25 Aug 2022

Corrigendum: Crystal structure of the monomeric extracellular domain of α9 nicotinic receptor subunit in complex with α-conotoxin RgIA: Molecular dynamics insights into RgIA binding to α9α10 nicotinic receptors

in Pharmacology of Ion Channels and Channelopathies

Marios Zouridakis
Athanasios Papakyriakou
Igor A. Ivanov
Igor E. Kasheverov
Victor Tsetlin
Socrates Tzartos
Petros Giastas

Frontiers in Pharmacology

doi 10.3389/fphar.2022.980202

1,110 views
1 citation

Brief Research Report

Published on 24 Aug 2022

Diagnostic yield and variant reassessment in the genes encoding Nav1.5 channel in Russian patients with Brugada syndrome

in Pharmacology of Ion Channels and Channelopathies

Elena Zaklyazminskaya
Anna Shestak
Dmitry Podolyak
Vera Komoliatova
Leonid Makarov
Anna Novitskaya
Amiran Revishvili

Frontiers in Pharmacology

doi 10.3389/fphar.2022.984299

2,436 views
1 citation

Editorial

Published on 22 Aug 2022

Editorial: Ion channels and transporters in diabetes and metabolic diseases

in Pharmacology of Ion Channels and Channelopathies

Michael Puljung
Elizabeth Haythorne
Maria Rohm
Natascia Vedovato

Frontiers in Pharmacology

doi 10.3389/fphar.2022.975812

1,557 views