Frontiers in Pharmacology | Predictive Toxicology

Original Research

Accepted on 13 Aug 2025

Risk Factors for Voriconazole-Associated Hepatotoxicity in Patients with Liver Dysfunction: A Retrospective Nested Case–control Study

in Predictive Toxicology

Jing Ren
Xinfeng Cai
Wei Ge
Jinlin Guo
Shan Wang
Qinhui Wang
Linna Liu
Le Yang
Qi Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1625003

Case Report

Accepted on 11 Aug 2025

A Case of Sudden Death Due to Occupational Nicotine Poisoning: Clinical Presentation and MRI Findings

in Predictive Toxicology

Jianjian Liu
Jianjian Liu
Xiang Dong Jian
Baotian Kan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1567380

136 views

Original Research

Published on 11 Aug 2025

Viral infections and related fatal adverse events associated with complement inhibitors for PNH: a real-world pharmacovigilance analysis in FAERS

in Predictive Toxicology

Jinman Zhong
Chang Chen
Yunman Xu
Yueping He
Jiewen Tan
Dan Xiong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1639685

419 views

Original Research

Published on 08 Aug 2025

Enhancing the confidence of potential targets enriched by similarity-centric models: the crucial role of the similarity threshold

in Predictive Toxicology

Ling-Fei Tong
You-Jin Ge
Su-Qing Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1574540

313 views

Original Research

Accepted on 06 Aug 2025

Histopathological examination and transcriptomic profiling reveal gossypol toxicityresponsive genes related to fertility in mice

in Predictive Toxicology

Teame Gereziher Mehari
Jiang Maorong
Gu Dandan
Jiaxi Qian
Jungfeng Tang
Ashenafi Kiros Wubshet
Hui Fang
Kai Wang
Dengbing Yao
Baohua Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1654299

118 views

Original Research

Published on 06 Aug 2025

Safety assessment of temozolomidee: real-world adverse event analysis from the FAERS database

in Predictive Toxicology

Yu Liu
Lan Ma
Xiaojia Fu
Yi Zhang
Jinyu Zheng
Zhongjun Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1578406

514 views

Case Report

Accepted on 05 Aug 2025

Case Report: Rhabdomyolysis following initiation of tirzepatide

in Predictive Toxicology

Jonas Michael Bodanowitz
Isabell Mattes
Micha Löbermann
Carlos Fritzsche

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1660785

Original Research

Published on 01 Aug 2025

Assessment of embryotoxic effects of quinoline yellow using attention-based convolutional neural network and machine learning in zebrafish model

in Predictive Toxicology

Magdalena Majdan
Piotr S. Maciąg
Agata Rogalska

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1606214

553 views

Original Research

Published on 29 Jul 2025

An occupational pipe leak poisoning

in Predictive Toxicology

Xiangxing Zhang
Tianzi Jian
Mengdi Shi
Chen Wang
Xiangdong Jian
Qilu Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1514565

434 views

Review

Published on 29 Jul 2025

Assessing biomarkers of exposure to carcinogens associated with combustible cigarettes, electronic cigarettes, and heated tobacco products: a systematic review and meta-analysis

in Predictive Toxicology

Yue Cao
Lin Zhang
Mengqi Yang
Jiaxuan Li
Xi Chen
Fangzhen Zheng
Jianqiang Zhang
Xiao Xu
Xiaona Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1630961

1,290 views

Original Research

Published on 25 Jul 2025

Bridging the gaps in detection of structural cardiotoxicity in stem cell-derived cardiomyocytes: promise of miR-133b, miR-184 and miR-208b-3p

in Predictive Toxicology

M. Cherubin
A. Delaunois
J. P. Valentin
M. Alaerts
P. J. Guns
V. Gryshkova

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1584734

581 views

Case Report

Published on 23 Jul 2025

Case Report: A case of occupational methyl iodide-induced encephalopathy

in Predictive Toxicology

Hongyu Liu
Ruikai Shang
Qiaoxin Tian
Yuru Liu
Xiangdong Jian

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1574692

441 views

Case Report

Published on 21 Jul 2025

Case Report: Infliximab for hydroxychloroquine-induced AGEP with IL17A and IL36RN mutations: a case report and management considerations

in Predictive Toxicology

Xiaoyun Jiang
Chunting Hua
Chenxi Feng
Hao Cheng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1580170

649 views

Original Research

Accepted on 14 Jul 2025

Integrated Neurobehavioral and Organ-Specific Safety Profiling of Baicalin: Acute/Subacute Toxicity Studies

in Predictive Toxicology

Jiali Yang
Mengyu Chen
Wan Zhang
Jia Liu
Jing Zhao
Xin Ping
Ye Lu
Pei He
Lin Pei

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1607919

198 views

Original Research

Published on 11 Jul 2025

Osteoporosis diagnosis and ingredients of prescription medications: a population-based study

in Predictive Toxicology

Xiaohong Huang
Zhendong Feng
Xiaohua Li
Dongxu Zhu
Yingze Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1522937

1,306 views

Original Research

Published on 01 Jul 2025

A retrospective observational study on case reports of adverse drug reactions (ADRs) to tirzepatide

in Predictive Toxicology

Mengmeng Huang
Guangwei Liu
Chuanzhou Zhang
Ying Wang
Shengfen Liu
Jun Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1608657

1,843 views